Michael Givskov
Professor
Bacteriology
Blegdamsvej 3B, 2200 København N, 22 Bygning 22, Building: 22-2-22
Member of:
- Published
Antibiotics inhibit tumor and disease activity in cutaneous T cell lymphoma
Lindahl, L. M., Willerslev-Olsen, A., Gjerdrum, L. M. R., Nielsen, P. R., Blümel, E., Rittig, A. H., Celis, P., Herpers, B., Becker, J. C., Stausbøl-Grøn, B., Wasik, M. A., Gluud, M., Fredholm, S., Buus, T. B., Johansen, C., Nastasi, C., Peiffer, L., Kubat, L., Bzorek, M., Eriksen, J. O. & 11 others, , 26 Sep 2019, In: Blood. 134, 13, p. 1072-1083Research output: Contribution to journal › Journal article › Research › peer-review
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N-Acyl-L-homoserine lactone autoinducers control production of an extracellular lipopeptide biosurfactant required for swarming motility of Serratia liquefaciens MG1
Lindum, P. W., Anthoni, U., Christophersen, C., Eberl, L., Molin, S. & Givskov, Michael, 1998, In: Journal of Bacteriology. 180, 23, p. 6384-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Molecular characterization of the pH-inducible and growth phase-dependent promoter P170 of Lactococcus lactis
Madsen, S. M., Arnau, J., Vrang, A., Givskov, Michael & Israelsen, H., 1999, In: Molecular Microbiology. 32, 1, p. 75-87 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence that halogenated furanones from Delisea pulchra inhibit acylated homoserine lactone (AHL)-mediated gene expression by displacing the AHL signal from its receptor protein
Manefield, M., de Nys, R., Kumar, N., Read, R., Givskov, Michael, Steinberg, P. & Kjelleberg, S., 1999, In: Microbiology. 145 ( Pt 2), p. 283-91 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Halogenated furanones from the red alga, Delisea pulchra, inhibit carbapenem antibiotic synthesis and exoenzyme virulence factor production in the phytopathogen Erwinia carotovora
Manefield, M., Welch, M., Givskov, Michael, Salmond, G. P. & Kjelleberg, S., 2001, In: F E M S Microbiology Letters. 205, 1, p. 131-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover
Manefield, M., Rasmussen, T. B., Henzter, M., Andersen, Jens Bo, Steinberg, P., Kjelleberg, S. & Givskov, Michael, 2002, In: Microbiology. 148, Pt 4, p. 1119-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A genetic switch controls Pseudomonas aeruginosa surface colonization
Manner, C., Dias Teixeira, R., Saha, D., Kaczmarczyk, A., Zemp, R., Wyss, F., Jaeger, T., Laventie, B. J., Boyer, S., Malone, J. G., Qvortrup, K., Andersen, Jens Bo, Givskov, Michael, Tolker-Nielsen, Tim, Hiller, S., Drescher, K. & Jenal, U., 2023, In: Nature Microbiology. 8, p. 1520–1533Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of a quorum sensing modulator pharmacophore by 3D small-molecule microarray screening
Marsden, D. M., Nicholson, R. L., Skindersoe, M. E., Galloway, W. R. J. D., Sore, H. F., Givskov, Michael, Salmond, G. P. C., Ladlow, M., Welch, M. & Spring, D. R., 7 Dec 2010, In: Organic & Biomolecular Chemistry. 8, 23, p. 5313-23 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.
Mathee, K., Ciofu, Oana, Sternberg, C., Lindum, P. W., Campbell, J. I., Jensen, P., Johnsen, A. H., Givskov, Michael, Ohman, D. E., Molin, S., Høiby, Niels & Kharazmi, A., 1999, In: Microbiology. 145 ( Pt 6), p. 1349-57 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial genotoxins induce T cell senescence
Mathiasen, S. L., Gall Mas, Laura, Pateras, I. S., Theodorou, S. D. P., Namini, Martin Rich Javadi, Hansen, Morten Bagge, Martin, O. C. B., Vadivel, Chella Krishna, Ntostoglou, K., Butter, D., Givskov, Michael, Geisler, Carsten, Akbar, A. N., Gorgoulis, V. G., Frisan, T., Ødum, Niels & Krejsgaard, T., 2021, In: Cell Reports. 35, 10, 109220.Research output: Contribution to journal › Journal article › Research › peer-review
Pseudomonas aeruginosa uses type III secretion system to kill biofilm-associated amoebae
Matz, C., Moreno, A. M., Alhede, M., Manefield, M., Hauser, A. R., Givskov, Michael & Kjelleberg, S., 2008, In: ISME Journal. 2, 8, p. 843-852 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemical mediation of bacterial surface colonisation by secondary metabolites from the red alga Delisea pulchra
Maximilian, R., De Nys, R., Holmström, C., Gram, L., Givskov, Michael, Crass, K., Kjelleberg, S. A. & Steinberg, P. D., 1998, In: Aquatic Microbial Ecology. 15, 3, p. 233-246 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination
Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.Research output: Contribution to journal › Journal article › Research › peer-review
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Biofilms and type III secretion are not mutually exclusive in Pseudomonas aeruginosa
Mikkelsen, H., Bond, N. J., Skindersoe, M. E., Givskov, Michael, Lilley, K. S. & Welch, M., 2009, In: Microbiology. 155, Pt 3, p. 687-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In silico analyses of metagenomes from human atherosclerotic plaque samples
Mitra, S., Drautz-Moses, D. I., Alhede, M., Maw, M. T., Liu, Y., Purbojati, R. W., Yap, Z. H., Kushwaha, K. K., Gheorghe, Alexandra Gabriella, Bjarnsholt, Thomas, Hansen, G. M., Sillesen, Henrik, Hougen, H. P., Hansen, Peter Riis, Yang, L., Tolker-Nielsen, Tim, Schuster, S. C. & Givskov, Michael, 2015, In: Microbiome. 3, p. 1-14 38.Research output: Contribution to journal › Journal article › Research › peer-review
Suicidal genetic elements and their use in biological containment of bacteria
Molin, S., Boe, L., Jensen, L. B., Kristensen, C. S., Givskov, Michael, Ramos, J. L. & Bej, A. K., 1993, In: Annual Review of Microbiology. 47, p. 139-66 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
Application of molecular tools for in situ monitoring of bacterial growth activity
Molin, S. & Givskov, Michael, 1999, In: Environmental Microbiology. 1, 5, p. 383-91 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis
Moser, C., Gennip, M. V., Bjarnsholt, Thomas, Jensen, Peter Østrup, Lee, B., Hougen, H. P., Calum, H., Ciofu, Oana, Givskov, Michael, Molin, S. & Høiby, Niels, 1 Feb 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 2, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel experimental Pseudomonas aeruginosa infection model mimicking long-term host-pathogen interactions in cystic fibrosis.
Moser, Claus Ernst, van Gennip, M., Bjarnsholt, Thomas, Jensen, P. Ø., Lee, B., Hougen, H. P., Calum, Henrik Pierre, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2009, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 117, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
In situ gene expression in mixed-culture biofilms: evidence of metabolic interactions between community members
Møller, S., Sternberg, C., Andersen, J. B., Christensen, B. B., Ramos, J. L., Givskov, Michael & Molin, S., 1998, In: Applied and Environmental Microbiology. 64, 2, p. 721-32 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Carbon starvation of Pseudomonas aeruginosa biofilms selects for dispersal insensitive mutants
Nair, H. A. S., Subramoni, S., Poh, W. H., Hasnuddin, N. T. B., Tay, M., Givskov, Michael, Tolker-Nielsen, Tim, Kjelleberg, S., McDougald, D. & Rice, S. A., 2021, In: BMC Microbiology. 21, 10 p., 255.Research output: Contribution to journal › Journal article › Research › peer-review
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A convenient procedure for the solid-phase synthesis of hydroxamic acids on PEGA resins
Nandurkar, N. S., Petersen, R., Qvortrup, K., Komnatnyy, V. V., Taveras, K. M., Le Quement, S. T., Frauenlob, R., Givskov, Michael & Nielsen, Thomas Eiland, 28 Dec 2011, In: Tetrahedron Letters. 52, 52, p. 7121-7124 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibiotic and biosurfactant properties of cyclic lipopeptides produced by fluorescent Pseudomonas spp. from the sugar beet rhizosphere
Nielsen, T. H., Sørensen, D., Tobiasen, C., Andersen, Jens Bo, Christophersen, C., Givskov, Michael & Sørensen, J., 2002, In: Applied and Environmental Microbiology. 68, 7, p. 3416-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The dlt genes play a role in antimicrobial tolerance of Streptococcus mutans biofilms
Nilsson, Carl Martin Peter, Rybtke, Morten Levin, Givskov, Michael, Høiby, Niels, Twetman, Svante & Tolker-Nielsen, Tim, Sep 2016, In: International Journal of Antimicrobial Agents. 48, 3, p. 298–304Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of putative exopolysaccharide genes on Pseudomonas putida KT2440 biofilm stability
Nilsson, M., Chiang, W., Fazli, M., Gjermansen, M., Givskov, Michael & Tolker-Nielsen, Tim, 2011, In: Environmental Microbiology. 13, 5, p. 1357-69Research output: Contribution to journal › Journal article › Research › peer-review
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Inactivation of the pgmA Gene in Streptococcus mutans Significantly Decreases Biofilm-Associated Antimicrobial Tolerance
Nilsson, Carl Martin Peter, Givskov, Michael, Twetman, Svante & Tolker-Nielsen, Tim, 2019, In: Microorganisms. 7, 9, 12 p., 310.Research output: Contribution to journal › Journal article › Research › peer-review
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A mariner transposon vector adapted for mutagenesis in oral streptococci
Nilsson, M., Christiansen, N., Høiby, Niels, Twetman, Svante, Givskov, Michael & Tolker-Nielsen, Tim, Jun 2014, In: MicrobiologyOpen. 3, 3, p. 333-40 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidative stress response plays a role in antibiotic tolerance of Streptococcus mutans biofilms
Nilsson, Carl Martin Peter, Jakobsen, Tim Holm, Givskov, Michael, Twetman, Svante & Tolker-Nielsen, Tim, 2019, In: Microbiology. 165, 3, p. 334-342Research output: Contribution to journal › Journal article › Research › peer-review
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Transposon Mutagenesis in Streptococcus Species
Nilsson, Carl Martin Peter, Givskov, Michael & Tolker-Nielsen, Tim, 2019, Microbial Transposon Mutagenesis: Protocols and Applications. Humana Press, p. 39-49 11 p. (Methods in Molecular Biology, Vol. 2016).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers
Olsen, J. A., Severinsen, R. E., Rasmussen, T. B., Hentzer, M., Givskov, Michael & Nielsen, J., 2002, In: Bioorganic & Medicinal Chemistry Letters. 12, 3, p. 325-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers
Olsen, J. A., Severinsen, R., Rasmussen, T. B., Hentzer, M., Givskov, Michael, Nielsen, J. & Nielsen, J., 11 Feb 2002, In: Bioorganic and Medicinal Chemistry Letters. 12, 3, p. 325-328 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparative microarray analysis reveals that the core biofilm-associated transcriptome of Pseudomonas aeruginosa comprises relatively few genes
Patell, S., Gu, M., Davenport, P., Givskov, Michael, Waite, R. D. & Welch, M., Jun 2010, In: Environmental Microbiology Reports. 2, 3, p. 440-448 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing inhibition: targeting chemical communication in gram-negative bacteria
Persson, T., Givskov, Michael & Nielsen, J., 2005, In: Current Medicinal Chemistry. 12, 26, p. 3103-15 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Rational design and synthesis of new quorum-sensing inhibitors derived from acylated homoserine lactones and natural products from garlic
Persson, T., Hansen, T. H., Rasmussen, T. B., Skindersø, M. E., Givskov, Michael & Nielsen, J., 2004, In: Organic & Biomolecular Chemistry. 3, 2, p. 253-62 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biofilm formation by Staphylococcus epidermidis on peritoneal dialysis catheters and the effects of extracellular products from Pseudomonas aeruginosa
Pihl, M., Arvidsson, A., Skepö, M., Nilsson, M., Givskov, Michael, Tolker-Nielsen, Tim, Svensäter, G. & Davies, J. R., Apr 2013, In: Pathogens and Disease. 67, 3, p. 192-198 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Small Molecule Anti-biofilm Agents Developed on the Basis of Mechanistic Understanding of Biofilm Formation
Qvortrup, K., Hultqvist, Louise Dahl, Nilsson, Carl Martin Peter, Jakobsen, Tim Holm, Jansen, C. U., Uhd, J., Andersen, Jens Bo, Nielsen, Thomas Eiland, Givskov, Michael & Tolker-Nielsen, Tim, 2019, In: Frontiers in Chemistry. 7, 27 p., 742.Research output: Contribution to journal › Review › Research › peer-review
Well-known quorum sensing inhibitors do not affect bacterial quorum sensing-regulated bean sprout spoilage
Rasch, M., Rasmussen, T. B., Andersen, J. B., Persson, T., Nielsen, J., Givskov, Michael & Gram, L., 2007, In: Journal of Applied Microbiology. 102, 3, p. 826-37 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Involvement of bacterial quorum-sensing signals in spoilage of bean sprouts
Rasch, M., Andersen, Jens Bo, Nielsen, K. F., Flodgaard, L. R., Christensen, Henrik, Givskov, Michael & Gram, L., 2005, In: Applied and Environmental Microbiology. 71, 6, p. 3321-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing signals are produced by Aeromonas salmonicida and quorum sensing inhibitors can reduce production of a potential virulence factor
Rasch, M., Kastbjerg, V. G., Bruhn, J. B., Dalsgaard, I., Givskov, Michael & Gram, L., 2007, In: Diseases of Aquatic Organisms. 78, 2, p. 105-13 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
An inhibitor of bacterial quorum sensing reduces mortalities caused by Vibriosis in rainbow trout (Oncorhynchus mykiss, Walbaum)
Rasch, M., Buch, C., Austin, B., Slierendrecht, W. J., Ekmann, K. S., Larsen, J. L., Johansen, C., Riedel, K., Eberl, L., Givskov, Michael & Gram, L., 2004, In: Systematic and Applied Microbiology. 27, 3, p. 350-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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How Delisea pulchra furanones affect quorum sensing and swarming motility in Serratia liquefaciens MG1
Rasmussen, T. B., Manefield, M., Andersen, Jens Bo, Eberl, L., Anthoni, U., Christophersen, C., Steinberg, P., Kjelleberg, S. & Givskov, Michael, 2000, In: Microbiology. 146 Pt 12, p. 3237-44 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing inhibitors: a bargain of effects
Rasmussen, T. B. & Givskov, Michael, 2006, In: Microbiology. 152, Pt 4, p. 895-904 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum-sensing inhibitors as anti-pathogenic drugs
Rasmussen, T. B. & Givskov, Michael, 2006, In: International Journal of Medical Microbiology. 296, 2-3, p. 149-61 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identity and effects of quorum-sensing inhibitors produced by Penicillium species
Rasmussen, T. B., Skindersoe, M. E., Bjarnsholt, T., Phipps, R. K., Christensen, K. B., Jensen, Peter Østrup, Andersen, Jens Bo, Koch, B., Larsen, T. O., Hentzer, M., Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: Microbiology. 151, Pt 5, p. 1325-40 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector
Rasmussen, T. B., Bjarnsholt, T., Skindersoe, M. E., Hentzer, M., Kristoffersen, P., Köte, M., Nielsen, J., Eberl, L. & Givskov, Michael, 2005, In: Journal of Bacteriology. 187, 5, p. 1799-814 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Methods for detecting acylated homoserine lactones produced by Gram-negative bacteria and their application in studies of AHL-production kinetics
Ravn, L., Christensen, A. B., Molin, S., Givskov, Michael & Gram, L., 2001, In: Journal of Microbiological Methods. 44, 3, p. 239-51 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Observations on the formation of deletions on monomeric and dimeric plasmids in Escherichia coli
Ravn, P., Givskov, Michael, Eegholm, K. M., Madsen, S. M. & Boe, L., 1994, In: Molecular Microbiology. 14, 2, p. 263-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Influence of food preservation parameters and associated microbiota on production rate, profile and stability of acylated homoserine lactones from food-derived Enterobacteriaceae
Ravn Flodgaard, L., Christensen, A. B., Molin, S., Givskov, Michael & Gram, L., 2003, In: International Journal of Food Microbiology. 84, 2, p. 145-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Bacterial signals and antagonists: the interaction between bacteria and higher organisms
Rice, S. A., Givskov, Michael, Steinberg, P. & Kjelleberg, S., 1999, In: Journal of Molecular Microbiology and Biotechnology. 1, 1, p. 23-31 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Detection and inhibition of bacterial cell-cell communication
Rice, S. A., McDougald, D., Givskov, Michael & Kjelleberg, S., 2008, In: Methods in Molecular Biology. 431, p. 55-68 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Key Players and Individualists of Cyclic-di-GMP Signaling in Burkholderia cenocepacia
Richter, A. M., Fazli, M., Schmid, N., Shilling, R., Suppiger, A., Givskov, Michael, Eberl, L. & Tolker-Nielsen, Tim, 2019, In: Frontiers in Microbiology. 9, 15 p., 3286.Research output: Contribution to journal › Journal article › Research › peer-review
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N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms
Riedel, K., Hentzer, M., Geisenberger, O., Huber, B., Steidle, A., Wu, H., Høiby, Niels, Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, Pt 12, p. 3249-62 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
N-acyl-L-homoserine lactone-mediated regulation of the lip secretion system in Serratia liquefaciens MG1
Riedel, K., Ohnesorg, T., Krogfelt, K. A., Hansen, T. S., Omori, K., Givskov, Michael & Eberl, L., 2001, In: Journal of Bacteriology. 183, 5, p. 1805-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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N-acyl homoserinelactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms
Riedel, K., Mentzer, M., Geisenberger, O., Huber, B., Steidle, A., Wu, H., Høiby, Niels, Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, p. 3249-3262Research output: Contribution to journal › Journal article › Research › peer-review
Identification and characterization of a GDSL esterase gene located proximal to the swr quorum-sensing system of Serratia liquefaciens MG1
Riedel, K., Talker-Huiber, D., Givskov, Michael, Schwab, H. & Eberl, L., 2003, In: Applied and Environmental Microbiology. 69, 7, p. 3901-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In Vitro Evaluation of Biofilm Dispersal as a Therapeutic Strategy To Restore Antimicrobial Efficacy
Roizman, D., Vidaillac, C., Givskov, Michael & Yang, L., 2017, In: Antimicrobial Agents and Chemotherapy. 61, 10, 5 p., e01088-17.Research output: Contribution to journal › Journal article › Research › peer-review
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The microorganisms in chronically infected end-stage and non-end-stage cystic fibrosis patients
Rudkjøbing, V. B., Thomsen, T. R., Alhede, M., Kragh, K. N., Nielsen, P. H., Johansen, U. R., Givskov, Michael, Høiby, Niels & Bjarnsholt, Thomas, Jul 2011, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 236-244 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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True microbiota involved in chronic lung infection of cystic fibrosis patients found by culturing and 16S rRNA gene analysis
Rudkjøbing, V. B., Thomsen, T. R., Alhede, M., Kragh, K. N., Nielsen, P. H., Johansen, U., Givskov, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2011, In: Journal of Clinical Microbiology. 49, 12, p. 4352-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The LapG protein plays a role in Pseudomonas aeruginosa biofilm formation by controlling the presence of the CdrA adhesin on the cell surface
Rybtke, Morten Levin, Berthelsen, J., Yang, L., Høiby, Niels, Givskov, Michael & Tolker-Nielsen, Tim, Dec 2015, In: MicrobiologyOpen. 4, 6, p. 917-930 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas aeruginosa Biofilm Infections: Community Structure, Antimicrobial Tolerance and Immune Response
Rybtke, Morten Levin, Hultqvist, Louise Dahl, Givskov, Michael & Tolker-Nielsen, Tim, 2015, In: Journal of Molecular Biology. 427, 23, p. 3628-3645Research output: Contribution to journal › Review › Research › peer-review
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Gauging and visualizing c-di-GMP levels in pseudomonas aeruginosa using fluorescence-based biosensors
Rybtke, Morten Levin, Chua, S. L., Yam, J. K. H., Givskov, Michael, Yang, L. & Tolker-Nielsen, Tim, Jan 2017, c-di-GMP Signaling: Methods and Protocols. Sauer, K. (ed.). Humana Press, Vol. 1657. p. 87-98 12 p. (Methods in Molecular Biology, Vol. 1657).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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The implication of Pseudomonas aeruginosa biofilms in infections
Rybtke, Morten Levin, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: Inflammation & Allergy - Drug Targets. 10, 2, p. 141-57 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fluorescence-based reporter for gauging cyclic di-GMP Levels in Pseudomonas aeruginosa.
Rybtke, Morten Levin, Borlee, B. R., Murakami, K., Irie, Y., Hentzer, M., Nielsen, T. E., Givskov, Michael, Parsek, M. R. & Tolker-Nielsen, Tim, 2012, In: Applied and Environmental Microbiology. 78, 15, p. 5060-5069 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
An attractive surface: gram-negative bacterial biofilms
Schembri, M., Givskov, Michael & Klemm, P., 2002, In: Science Signaling. 2002, 132, p. re6Research output: Contribution to journal › Journal article › Research › peer-review
Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein
Schreiber, K., Boes, N., Eschbach, M., Jaensch, L., Wehland, J., Bjarnsholt, T., Givskov, Michael, Hentzer, M. & Schobert, M., 2006, In: Journal of Bacteriology. 188, 2, p. 659-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of Burkholderia cenocepacia strain H111 virulence factors using nonmammalian infection hosts
Schwager, S., Agnoli, K., Köthe, M., Feldmann, F., Givskov, Michael, Carlier, A. & Eberl, L., 2013, In: Infection and Immunity. 81, 1, p. 143-53 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quorum sensing in Aeromonas salmonicida subsp. achromogenes and the effect of the autoinducer synthase AsaI on bacterial virulence
Schwenteit, J., Gram, L., Nielsen, K. F., Fridjonsson, O. H., Bornscheuer, U. T., Givskov, Michael & Gudmundsdottir, B. K., 2011, In: Veterinary Microbiology. 147, 3-4, p. 389-97Research output: Contribution to journal › Journal article › Research › peer-review
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Functional Amyloids Keep Quorum-sensing Molecules in Check
Seviour, T., Hansen, S. H., Yang, L., Yau, Y. H., Wang, V. B., Stenvang, M. R., Christiansen, G., Marsili, E., Givskov, Michael, Chen, Y., Otzen, D. E., Nielsen, P. H., Geifman-Shochat, S., Kjelleberg, S. & Dueholm, M. S., 6 Mar 2015, In: Journal of Biological Chemistry. 290, 10, p. 6457-6469 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional
Shrout, J. D., Chopp, D. L., Just, C. L., Hentzer, M., Givskov, Michael & Parsek, M. R., 2006, In: Molecular Microbiology. 62, 5, p. 1264-77 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The contribution of cell-cell signaling and motility to bacterial biofilm formation
Shrout, J. D., Tolker-Nielsen, Tim, Givskov, Michael & Parsek, M. R., May 2011, In: M R S Bulletin. 36, 5, p. 367-373 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa
Skindersoe, M. E., Alhede, M., Phipps, R., Yang, L., Jensen, P. O., Rasmussen, T. B., Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 1 Oct 2008, In: Antimicrobial Agents and Chemotherapy. 52, 10, p. 3648-63 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa quorum-sensing signal molecules interfere with dendritic cell-induced T-cell proliferation
Skindersoe, M. E., Zeuthen, L. H., Brix, Susanne, Fink, L. N., Lazenby, J., Whittall, C., Williams, P., Diggle, S. P., Frøkiær, Hanne, Cooley, M. & Givskov, Michael, 2009, In: FEMS Immunology and Medical Microbiology. 55, 3, p. 335-45 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quorum sensing antagonism from marine organisms
Skindersoe, M. E., Ettinger-Epstein, P., Rasmussen, T. B., Bjarnsholt, Thomas, de Nys, R. & Givskov, Michael, 2007, In: Marine Biotechnology. 10, 1, p. 56-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing antagonism from marine organisms
Skindersoe, M. E., Ettinger-Epstein, P., Rasmussen, T. B., Bjarnsholt, T., de Nys, R. & Givskov, Michael, 2007, In: Marine Biotechnology. 10, 1, p. 56-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of LasR ligands through a virtual screening approach
Skovstrup, S., Le Quement, S. T., Hansen, T., Jakobsen, Tim Holm, Harmsen, M., Tolker-Nielsen, Tim, Nielsen, T. E., Givskov, Michael & Taboureau, O., 2013, In: ChemMedChem. 8, 1, p. 157-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Garlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis--a pilot randomized controlled trial
Smyth, A. R., Cifelli, P. M., Ortori, C. A., Righetti, K., Lewis, S., Erskine, P., Holland, E. D., Givskov, Michael, Williams, P., Cámara, M., Barrett, D. A. & Knox, A., 1 Apr 2010, In: Pediatric Pulmonology. 45, 4, p. 356-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through loss of the Rieske cytochrome bc1 sub-unit
Soh, E., Smith, F., Gimenez, M. R., Yang, L., Vejborg, R. M., Fletcher, M., Halliday, N., Bleves, S., Heeb, S., Camara, M., Givskov, Michael, Hardie, K. R., Tolker-Nielsen, Tim, Ize, B. & Williams, P., 2021, bioRxiv, 43 p.Research output: Working paper › Preprint › Research
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Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through lack of the Rieske cytochrome bc1sub-unit
Soh, E. Y. C., Smith, F., Gimenez, M. R., Yang, L., Vejborg, R. M., Fletcher, M., Halliday, N., Bleves, S., Heeb, S., Cámara, M., Givskov, Michael, Hardie, K. R., Tolker-Nielsen, Tim, Ize, B. & Williams, P., 2021, In: PLOS Pathogens. 17, 8, 25 p., e1009425.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and biological evaluation of triazole-containing N-acyl homoserine lactones as quorum sensing modulators
Stacy, D. M., Le Quement, S. T., Hansen, C., Clausen, J. W., Tolker-Nielsen, Tim, Brummond, J. W., Givskov, Michael, Nielsen, T. E. & Blackwell, H. E., 2013, In: Organic & Biomolecular Chemistry. 11, 6, p. 938-54 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Visualization of N-acylhomoserine lactone-mediated cell-cell communication between bacteria colonizing the tomato rhizosphere
Steidle, A., Sigl, K., Schuhegger, R., Ihring, A., Schmid, M., Gantner, S., Stoffels, M., Riedel, K., Givskov, Michael, Hartmann, A., Langebartels, C. & Eberl, L., 2001, In: Applied and Environmental Microbiology. 67, 12, p. 5761-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification and characterization of an N-acylhomoserine lactone-dependent quorum-sensing system in Pseudomonas putida strain IsoF
Steidle, A., Allesen-Holm, M., Riedel, K., Berg, G., Givskov, Michael, Molin, S. & Eberl, L., 2002, In: Applied and Environmental Microbiology. 68, 12, p. 6371-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Distribution of bacterial growth activity in flow-chamber biofilms
Sternberg, C., Christensen, B. B., Johansen, T., Toftgaard Nielsen, A., Andersen, J. B., Givskov, Michael & Molin, S., 1999, In: Applied and Environmental Microbiology. 65, 9, p. 4108-17 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cranberry (Vaccinium macrocarpon) oligosaccharides decrease biofilm formation by uropathogenic Escherichia coli
Sun, J., Marais, J. P. J., Khoo, C., LaPlante, K., Vejborg, R. M., Givskov, Michael, Tolker-Nielsen, Tim, Seeram, N. P. & Rowley, D. C., Aug 2015, In: Journal of Functional Foods. 17, p. 235-242 8 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Acetic acid and a buffer
Bjarnsholt, Thomas, Givskov, Michael, P, H., Høiby, Niels, PO, J., HK, J. & K, K., 2010, Patent No. WO2009155931, 30 Jan 2010Research output: Patent
- Published
In vitro and In vivo efficacy of an LpxC inhibitor, CHIR-090, alone or combined with colistin against Pseudomonas aeruginosa biofilm
Tan, J. H., Vidaillac, C., Yam, J. K. H., Chua, S. L., Givskov, Michael & Yang, L., 2017, In: Antimicrobial Agents and Chemotherapy. 61, 7, 9 p., e02223-16.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative genomic analysis of rapid evolution of an extreme-drug- resistant Acinetobacter baumannii clone
Tan, S., Chua, S. L., Liu, Y., Høiby, Niels, Andersen, L. P., Givskov, Michael, Song, Z. & Yang, L., 2013, In: Genome Biology and Evolution. p. 807–818Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Emerging frontiers in detection and control of bacterial biofilms
Tan, S. Y. E., Chew, S. C., Tan, S. Y. Y., Givskov, Michael & Yang, L., 2014, In: Current Opinion in Biotechnology. 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of five structurally unrelated quorum-sensing inhibitors of Pseudomonas aeruginosa from a natural-derivative database
Tan, S. Y. Y., Chua, S. L., Chen, Y., Rice, S. A., Kjelleberg, S., Nielsen, Thomas Eiland, Yang, L. & Givskov, Michael, Nov 2013, In: Antimicrobial Agents and Chemotherapy. 57, 11, p. 5629-5641 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative systems biology analysis to study the mode of action of the isothiocyanate compound Iberin on Pseudomonas aeruginosa
Tan, S. Y., Liu, Y., Chua, S. L., Vejborg, R. M., Jakobsen, Tim Holm, Chew, S. C., Li, Y., Nielsen, T. E., Tolker-Nielsen, Tim, Yang, L. & Givskov, Michael, Nov 2014, In: Antimicrobial Agents and Chemotherapy. 58, 11, p. 6648-59 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Draft Genome Sequence of the Model Naphthalene-Utilizing Organism Pseudomonas putida OUS82
Tay, M., Roizman, D., Cohen, Y., Tolker-Nielsen, Tim, Givskov, Michael & Yang, L., 2014, In: Genome Announcements. 2, 1, p. 1 1 p., e01161-13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Intracellular Cyclic di-AMP Levels Sensitize Streptococcus gallolyticus subsp. gallolyticus to Osmotic Stress and Reduce Biofilm Formation and Adherence on Intestinal Cells
Teh, W. K., Dramsi, S., Tolker-Nielsen, Tim, Yang, L. & Givskov, Michael, 2019, In: Journal of Bacteriology. 201, 6, p. 1-16 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of TelE, a T7SS LXG Effector Exhibiting a Conserved C-Terminal Glycine Zipper Motif Required for Toxicity
Teh, W. K., Ding, Y., Gubellini, F., Filloux, A., Poyart, C., Givskov, Michael & Dramsi, S., 2023, In: Microbiology Spectrum. 11, 4, e0148123.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative genomic analysis of malariamosquito vector-associated novel pathogen elizabethkingia anophelis
Teo, J., Tan, S., Liu, Y., Tay, M., Ding, Y., Li, Y., Kjelleberg, S., Givskov, Michael, Lin, R. T. P. & Yang, L., 2014, In: Genome Biology and Evolution. p. 1158–1165 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First case of E anophelis outbreak in an intensive-care unit
Teo, J., Tan, S. Y. Y., Tay, M., Ding, Y., Kjelleberg, S., Givskov, Michael, Lin, R. T. P. & Yang, L., 2013, In: The Lancet. 382, 9895, p. 855-856 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Fusaric acid and analogues as gram-negative bacterial quorum sensing inhibitors
Thanh Tung, T., Jakobsen, Tim Holm, Dao, T. T., Fuglsang, Anja Thoe, Givskov, Michael, Christensen, Søren Brøgger & Nielsen, J., 2017, In: European Journal of Medicinal Chemistry. 126, p. 1011-1020 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The bacteriology of chronic venous leg ulcer examined by culture-independent molecular methods
Thomsen, T. R., Aasholm, M. S., Rudkjøbing, V. B., Saunders, A. M., Bjarnsholt, Thomas, Givskov, Michael, Kirketerp-Møller, K. & Nielsen, P. H., 2010, In: Wound Repair and Regeneration. 18, 1, p. 38-49 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The bactericidal activity of β-lactam antibiotics is increased by metabolizable sugar species
Thorsing, M., Bentin, Thomas, Givskov, Michael, Tolker-Nielsen, Tim & Goltermann, Lise, Oct 2015, In: Microbiology. 161, 10, p. 1999-2007 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Pseudomonas aeruginosa Type III Translocon Is Required for Biofilm Formation at the Epithelial Barrier
Tran, C. S., Rangel, S. M., Almblad, H., Kierbel, A., Givskov, Michael, Tolker-Nielsen, Tim, Hauser, A. R. & Engel, J. N., Nov 2014, In: P L o S Pathogens. 10, 11, p. 1-11 12 p., e1004479.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes
Van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Phipps, R., Jensen, Peter Østrup, Christophersen, L., Pamp, S. J., Moser, C., Mikkelsen, P. J., Koh, A. Y., Tolker-Nielsen, Tim, Pier, G. B., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Jul 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 7, p. 537-46 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing in Serratia
Van Houdt, R., Givskov, Michael & Michiels, C. W., 2007, In: FEMS Microbiology Reviews. 31, 4, p. 407-24 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5838523
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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C-di-GMP regulates Pseudomonas aeruginosa stress response to tellurite during both planktonic and biofilm modes of growth
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Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes
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