Niels Høiby

Niels Høiby

Professor, No job title

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    ORCID: 0000-0002-1347-725X

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    1. Published

      125 years anniversary of Christian Gram's staining method

      Høiby, Niels, 2008, In: ESCMID NEWS. 2, p. 49-51 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes

      Alhede, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Phipps, R. K., Moser, Claus Ernst, Christophersen, L., Hultqvist, Louise Dahl, van Gennip, M., Parsek, M., Høiby, Niels, Rasmussen, T. B. & Givskov, Michael, 2009, In: Microbiology. 155, 11, p. 3500-3508 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Pseudomonas aeruginosa septicaemia in a patient with severe Plasmodium falciparum

      Kharazmi, A., Høiby, Niels & Theander, Thor Grundtvig, 1987, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 81, 1, p. 49-50 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      P. aeruginosa flow-cell biofilms are enhanced by repeated phage treatments but can be eradicated by phage-ciprofloxacin combination: —monitoring the phage–P. aeruginosa biofilms interactions

      Henriksen, K., Rørbo, N., Rybtke, Morten Levin, Martinet, M. G., Tolker-Nielsen, Tim, Høiby, Niels, Middelboe, Mathias & Ciofu, Oana, 2019, In: Pathogens and Disease. 77, 2, 11 p., ftz011.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients

      Høiby, Niels, Johansen, Helle Krogh, Moser, Claus Ernst, Ciofu, Oana, Jensen, Peter Østrup, Kolpen, Mette, Mandsberg, L., Givskov, Michael, Molin, S. & Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer, p. 167-184 18 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    6. Published

      Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor

      Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Feb 2018, In: International Wound Journal. 15, 1, p. 123-132

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Burmølle, Mette, Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, Claus Ernst, Molin, S., Høiby, Niels & Givskov, Michael, Feb 2005, In: Microbiology. 151, Pt 2, p. 373-83 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Staphylococcus aureus alters growth activity, autolysis and antibiotic tolerance in a human host-adapted Pseudomonas aeruginosa lineage

      Michelsen, C. F., Christensen, A. J., Bojer, Martin Saxtorph, Høiby, Niels, Ingmer, Hanne & Jelsbak, L., 2014, In: Journal of Bacteriology. 196, 22, p. 3903-3911 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      A cohort study of the Copenhagen CF Centre eradication strategy against Staphylococcus aureus in patients with CF

      Dalbøge, C. S., Pressler, T., Høiby, Niels, Nielsen, Kim G. & Johansen, Helle Krogh, Jan 2013, In: Journal of Cystic Fibrosis. 12, 1, p. 42-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production

      Sautter, R., Ramos, D., Schneper, L., Ciofu, Oana, Wassermann, T., Koh, C., Heydorn, A., Hentzer, M., Høiby, Niels, Kharazmi, A., Molin, S., Devries, C. A., Ohman, D. E. & Mathee, K., 1 May 2012, In: Gene. 498, 2, p. 242-253 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia

      Alanin, M. C., Nielsen, K. G., von Buchwald, Christian, Skov, M., Aanæs, Kasper, Høiby, Niels & Johansen, Helle Krogh, Dec 2015, In: Clinical Microbiology and Infection. 21, 12, p. 1093.e1–1093.e7 7 p., 1093.e.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      A mariner transposon vector adapted for mutagenesis in oral streptococci

      Nilsson, M., Christiansen, N., Høiby, Niels, Twetman, Svante, Givskov, Michael & Tolker-Nielsen, Tim, Jun 2014, In: MicrobiologyOpen. 3, 3, p. 333-40 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      A non-fatal case of invasive zygomycete (Lichtheimia corymbifera) infection in an allogeneic haematopoietic cell transplant recipient

      Eickhardt, S., Braendstrup, P., Clasen-Linde, E., Jensen, K. E., Alhede, M., Bjarnsholt, Thomas, Høiby, Niels, Vindeløv, L. & Moser, Claus Ernst, May 2013, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 121, 5, p. 456-9 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      A normally occurring staphylococcus antibody in human serum - Commentary

      Forsgren, A. & Høiby, Niels, 2007, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 115, 5, p. 540-541 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      A personal history of research on microbial biofilms and biofilm infections

      Høiby, Niels, Apr 2014, In: Pathogens and Disease. 70, 3, p. 205-211 7 p.

      Research output: Contribution to journal › Review › Research › peer-review

    16. Published

      A short history of microbial biofilms and biofilm infections

      Høiby, Niels, Apr 2017, In: APMIS. 125, 4, p. 272-275 4 p.

      Research output: Contribution to journal › Review › Research › peer-review

    17. Published

      A systematic review of studies on the faecal microbiota in anorexia nervosa: future research may need to include microbiota from the small intestine

      Schwensen, H. F., Kan, C., Treasure, J., Høiby, Niels & Sjögren, M., 2018, In: Eating and Weight Disorders. 23, 4, p. 399-418

      Research output: Contribution to journal › Review › Research › peer-review

    18. Published

      Acetic acid and a buffer

      Bjarnsholt, Thomas, Givskov, Michael, P, H., Høiby, Niels, PO, J., HK, J. & K, K., 2010, Patent No. WO2009155931, 30 Jan 2010

      Research output: Patent

    19. Published

      Activation of pulmonary and lymph node dendritic cells during chronic Pseudomonas aeruginosa lung infection in mice

      Damlund, D. S. M., Christophersen, L., Jensen, Peter Østrup, Alhede, M., Høiby, Niels & Moser, Claus Ernst, Jun 2016, In: APMIS - Journal of Pathology, Microbiology and Immunology. 124, 6, p. 500-507 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Activation of the immune defence in blood and lung after ginseng treatment in a rat model with chronic Pseudomonas aeruginosa pneumonia

      Song, Z. J., Wu, H., Kharazmi, A., Faber, V., Moser, C., Johansen, Helle Krogh & Høiby, Niels, 1999, In: Netherlands Journal of Medicine. 54, p. 70-70

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

      Folkesson, A., Jelsbak, L., Yang, L., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels & Molin, S., Dec 2012, In: Nature Reviews. Microbiology. 10, 12, p. 841-851 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Adaptation of Pseudomonas aeruginosa to the chronic phenotype by mutations in the algTmucABD operon in isolates from Brazilian cystic fibrosis patients

      Caçador, N. C., Paulino da Costa Capizzani, C., Monteiro Marin Torres, L. A. G., Galetti, R., Ciofu, Oana, Lúcia da Costa Darini, A. & Høiby, Niels, 2018, In: PLoS ONE. 13, 11, 11 p., e0208013.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Adaptive Immune Response to Mycobacterium abscessus Complex (MABSC) in Cystic Fibrosis and the Implications of Cross-Reactivity

      Mauch, R. M., Jensen, Peter Østrup, Qvist, T., Kolpen, M., Moser, Claus Ernst, Pressler, T., Nolasco da Silva, M. T., Høiby, Niels & Copenhagen Study Group on Mycobacterial Infections in Cystic Fibrosis, C. S. G. O. M. I. I. C. F., 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 858398.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Adjunctive S100A8/A9 Immunomodulation Hinders Ciprofloxacin Resistance in Pseudomonas aeruginosa in a Murine Biofilm Wound Model

      Laulund, A. S., Schwartz, F., Trøstrup, H., Thomsen, K., Christophersen, L., Calum, Henrik Pierre, Ciofu, Oana, Høiby, Niels & Moser, Claus Ernst, 2021, In: Frontiers in Cellular and Infection Microbiology. 11, 652012.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Goetze, J. P., Nielsen, P. R., Thomsen, K., Enevold, C., Høiby, Niels, Jensen, Peter Østrup, Bundgård, Henning & Moser, Claus Ernst, 2019, In: PLoS ONE. 14, 4, 16 p., e0215333.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing

      Jakobsen, Tim Holm, van Gennip, M., Phipps, R. K., Shanmugham, M. S., Hultqvist, Louise Dahl, Alhede, M., Skindersoe, M. E., Rasmussen, T. B., Friedrich, K., Uthe, F., Jensen, Peter Østrup, Moser, Claus Ernst, Nielsen, Kristian Fog, Eberl, L., Larsen, T. O., Tanner, D. A., Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., May 2012, In: Antimicrobial Agents and Chemotherapy. 56, 5, p. 2314-25 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Alginate in infection

      Pedersen, S. S., Høiby, Niels, Espersen, F. & Kharazmi, A., 1991, In: Antibiotics and Chemotherapy. 44, p. 68-79 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Anaerobic bacteria in biofilm –and their tolerance to antibiotics

      Kragh, K. N., Kühl, Michael, Gregersen, A., Tvede, M., Høiby, Niels & Bjarnsholt, Thomas, 2011.

      Research output: Contribution to conference › Poster › Research

    29. Published

      Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

      Thomsen, K., Kobayashi, O., Kishi, K., Shirai, R., Jensen, Peter Østrup, Heydorn, A., Hentzer, M., Calum, Henrik Pierre, Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 7, p. 458-476

      Research output: Contribution to journal › Review › Research › peer-review

    30. Published

      Animal models of chronic wound care: the application of biofilms in clinical research

      Trøstrup, H., Thomsen, K., Calum, Henrik Pierre, Høiby, Niels & Moser, Claus Ernst, 2016, In: Chronic Wound Care Management and Research. 3, p. 123-132 10 p.

      Research output: Contribution to journal › Review › Research › peer-review

    31. Published

      Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils

      Thomsen, K., Christophersen, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, Claus Ernst & Høiby, Niels, Jul 2016, In: Human Vaccines & Immunotherapeutics. 12, 7, p. 1690-1699 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils

      Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Jul 2015, In: Infection and Immunity. 83, 7, p. 2686-2693 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model

      Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Anti-biofilm Approach in Infective Endocarditis Exposes New Treatment Strategies for Improved Outcome

      Lerche, C. J., Schwartz, F., Theut, M., Fosbøl, E. L., Iversen, Kasper, Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2021, In: Frontiers in Cell and Developmental Biology. 9, 25 p., 643335.

      Research output: Contribution to journal › Review › Research › peer-review

    35. Published

      Antibiofilm Properties of Acetic Acid

      Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model

      Cao, B., Christophersen, L., Thomsen, K., Sønderholm, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2015, In: The Journal of antimicrobial chemotherapy. 70, 7, p. 2057-2063 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system

      Mandsberg, L. F., Ciofu, Oana, Kirkby, N., Christiansen, L. E., Poulsen, Henrik Enghusen, Høiby, Niels, Mandsberg, L. F., Ciofu, O., Kirkby, N., Christiansen, L. E., Poulsen, Henrik Enghusen & Høiby, N., 1 Jun 2009, In: Antimicrobial Agents and Chemotherapy. 53, 6, p. 2483-91 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Antibiotic resistance of bacterial biofilms

      Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael, Molin, S. & Ciofu, Oana, 2010, In: International Journal of Antimicrobial Agents. 35, 4, p. 322-332 11 p.

      Research output: Contribution to journal › Review › Research › peer-review

    39. Published

      Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus

      Döring, G., Conway, S., Heijerman, H. G. M., Hodson, M. E., Høiby, Niels, Smyth, A. & Touw, D. J., 2000, In: European Respiratory Journal. 16, p. 749-767

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Antibiotic therapy as personalized medicine - general considerations and complicating factors

      Moser, Claus Ernst, Lerche, C. J., Thomsen, K., Hartvig, T., Schierbeck, J., Jensen, Peter Østrup, Ciofu, Oana & Høiby, Niels, 2019, In: APMIS. 127, 5, p. 361-371

      Research output: Contribution to journal › Review › Research › peer-review

    41. Published

      Antibiotika resistens hos E. coli isoleret fra raske normalpersoner

      Tvede, M., Høiby, Niels, Agerholm Larsen, L., Raben, A. & Astrup, A., 2001, In: Ugeskrift for læger. 163, 36, p. 4868-4871 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Antibodies against Pseudomonas aeruginosa chromosomal beta-lactamase inpatients with cystic fibrosis are markers of the development of resistance of P. aeruginosa to beta-lactams.

      Ciofu, Oana, Giwercman, B., Walter-Rasmussen, J., Pressler, T., Pedersen, S. S. & Høiby, Niels, 1995, In: Journal of Antimicrobial Chemotherapy. 35, 2, p. 295-304 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Antibodies against beta-lactamase can improve ceftazidime treatment of lung infection with beta-lactam-resistant Pseudomonas aeruginosa in a rat model of chronic lung infection.

      Ciofu, Oana, Bagge, N. & Høiby, Niels, 2002, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 110, 12, p. 881-91 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Antibodies against chromosomal beta-lactamase.

      Giwercman, B., Rasmussen, J. W., Ciofu, Oana, Clemmentsen, I., Schumacher, H. & Høiby, Niels, 1994, In: Antimicrobial Agents and Chemotherapy. 38, 10, p. 2306-10 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Antibody response against Pseudomonas aeruginosa and its relationship with immune mediators in the upper and lower airways of cystic fibrosis patients

      Mauch, R. M., Hentschel, J., Aanæs, Kasper, Barucha, A., Nolasco da Silva, M. T., Levy, C. E., Høiby, Niels & Mainz, J. G., 2020, In: Pediatric Pulmonology. 55, 4, p. 959-967

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Antibody response against Mycobacterium avium complex in cystic fibrosis patients measured by a novel IgG ELISA test

      Ravnholt, C., Qvist, T., Kolpen, M., Pressler, T., Skov, M. & Høiby, Niels, 2019, In: Journal of Cystic Fibrosis. 18, 4, p. 516-521

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Antibody response to Pseudomonas aeruginosa in cystic fibrosis patients: a marker of therapeutic success? - A 30-year cohort study of survival in Danish CF patients after onset of chronic P. aeruginosa lung infection

      Johansen, Helle Krogh, Nørregaard, L., Gøtzsche, P. C., Pressler, T., Koch, C. & Høiby, Niels, 2004, In: Pediatric Pulmonology. 37, 5, p. 427-432

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Antibody response to major cross-reactive Legionella antigens during infection

      Bangsborg, Jette Marie, Shand, G. & Høiby, Niels, 1993, Legionella: Current status and emerging perspectives. USA: ASM, p. 26-29

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    49. Published

      Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients

      Molchanova, N., Wang, H., Hansen, Paul Robert, Høiby, Niels, Nielsen, Hanne Mørck & Franzyk, Henrik, 2019, In: Frontiers in Microbiology. 10, 9 p., 275.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

      Ciofu, Oana, Tolker-Nielsen, Tim, Jensen, Peter Østrup, Wang, H. & Høiby, Niels, 2015, In: Advanced Drug Delivery Reviews. 85, p. 7-23 17 p.

      Research output: Contribution to journal › Review › Research › peer-review

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