Niels Høiby

Niels Høiby

Professor, No job title

Member of:


    1. Published

      Diagnosis and treatment of cystic fibrosis

      Koch, C. & Høiby, Niels, 2000, In: Tanaffos. 67, p. 239-247

      Research output: Contribution to journalJournal articleResearchpeer-review

    2. Published

      O-2 AFFECTS THE ACTIVITY OF AMIKACIN ON MYCOBACTERIUM ABSCESSUS BIOFILM

      Kolpen, M., Ravnholt, C., Qvist, T., Kragh, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, Sep 2017, In: Pediatric Pulmonology. 52, S47, p. S359-S360 379.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    3. Published

      RE-SENSITIZATION OF ANOXIC PSEUDOMONAS AERUGINOSA BIOFILMS WITH RE-OXYGENATION USING HYPERBARIC OXYGEN TREATMENT

      Kolpen, Mette, Mousavi, N., Sams, T., Kragh, K. N., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, P. O., Oct 2015, In: Pediatric Pulmonology. 50, S41, p. 312-312 1 p., 322.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    4. Published

      Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment

      Kolpen, Mette, Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.

      Research output: Contribution to journalLetterResearchpeer-review

    5. Published

      Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin

      Kolpen, Mette, Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Nitric oxide production by polymorphonuclear leukocytes in sputum from cystic fibrosis patients with chronic lung infection

      Kolpen, Mette, Bjarnsholt, Thomas, Moser, C., Hansen, C. R., Kühl, Michael, Høiby, Niels & Jensen, P. Ø., 2010, In: Journal of Cystic Fibrosis. Supplement 1, p. S49 1 p.

      Research output: Contribution to journalConference abstract in journalResearch

    7. Published

      Nitric oxide production by polymorphonuclear leukocytes in sputum from cystic fibrosis patients with chronic lung infection

      Kolpen, M., Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Kühl, M., Høiby, Niels & Jensen, Peter Østrup, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    8. Published

      Nitric oxide production by polymorphonuclear leukocytes in infected cystic fibrosis sputum consumes oxygen

      Kolpen, Mette, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Rickelt, L. F., Kühl, Michael, Hempel, C., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Clinical and Experimental Immunology. 177, 1, p. 310–319 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Denitrification by cystic fibrosis pathogens - Stenotrophomonas maltophilia is dormant in sputum

      Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas, Line, L., Hansen, C. R., Dalbøge, C. S., Hansen, N., Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2015, In: International Journal of Medical Microbiology. 305, 1, p. 1-10 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

      Kolpen, Mette, Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Liengaard, L., Kharazmi, A., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: PLOS ONE. 9, 1, p. e84353 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

      Kolpen, Mette, Hansen, C. R., Bjarnsholt, Thomas, Moser, C., Hultqvist, Louise Dahl, van Gennip, M., Ciofu, Oana, Mandsberg, L., Kharazmi, A., Döring, G., Givskov, Michael, Høiby, Niels & Jensen, Peter Østrup, 1 Jan 2010, In: Thorax. 65, 1, p. 57-62 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

      Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions

      Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Anaerobic bacteria in biofilm –and their tolerance to antibiotics

      Kragh, K. N., Kühl, Michael, Gregersen, A., Tvede, M., Høiby, Niels & Bjarnsholt, Thomas, 2011.

      Research output: Contribution to conferencePosterResearch

    15. Published

      Polymorphonuclear leukocytes restrict growth of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients

      Kragh, K. N., Alhede, M., Jensen, Peter Østrup, Moser, Claus Ernst, Scheike, Thomas, Jacobsen, C. S., Poulsen, Steen Seier, Eickhardt-Sørensen, S. R., Trostrup, H., Christoffersen, L., Hougen, H. P., Rickelt, L. F., Kühl, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2014, In: Infection and Immunity. 82, 11, p. 4477-4486 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Induction of oxidative burst response in human neutrophils by immune complexes made in vitro of lipopolysaccharide and hyperimmune serum from chronically infected patients

      Kronborg, Gitte, Fomsgaard, A., Jensen, E. T., Kharazmi, A. & Høiby, Niels, 1993, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 101, 11, p. 887-94 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Experimental chronic Pseudomonas aeruginosa lung infection in rats. Non-specific stimulation with LPS reduces lethality as efficiently as specific immunization

      Lange, Kai, Hougen, H. P., Høiby, Niels, Fomsgaard, A., Rygaard, J. & Johansen, Helle Krogh, 1995, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 103, 5, p. 367-74 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Kolera i Danmark--et importeret sygdomstilfoelde

      Lange, Kai, Pedersen, K. M., Nielsen, S. E. & Høiby, Niels, 17 Apr 1995, In: Ugeskrift for Laeger. 157, 16, p. 2325-6 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Use of cultivation-dependent and -independent techniques to assess contamination of central venous catheters: a pilot study

      Larsen, M. K., Thomsen, T. R., Moser, C., Nielsen, P. H. & Høiby, Niels, 2008, In: BMC Clinical Pathology. 8, p. 10 1 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Adjunctive S100A8/A9 Immunomodulation Hinders Ciprofloxacin Resistance in Pseudomonas aeruginosa in a Murine Biofilm Wound Model

      Laulund, A. S., Schwartz, F., Trøstrup, H., Thomsen, K., Christophersen, L., Calum, Henrik Pierre, Ciofu, Oana, Høiby, Niels & Moser, Claus Ernst, 2021, In: Frontiers in Cellular and Infection Microbiology. 11, 652012.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Hyperbaric oxygen therapy augments ciprofloxacin effect against Pseudomonas aeruginosa biofilm infected chronic wounds in a mouse model

      Laulund, A. S., Schwartz, F. A., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Calum, Henrik Pierre, Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 5, 100100.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Hyperbaric oxygen therapy counteracts Pseudomonas aeruginosa biofilm micro-compartment phenomenon in murine thermal wounds

      Laulund, A. S., Schwartz, F. A., Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 6, 8 p., 100159.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Lactoferricin-inspired peptide AMC-109 augments the effect of ciprofloxacin against Pseudomonas aeruginosa biofilm in chronic murine wounds

      Laulund, A. S., Schwartz, F. A., Christophersen, L., Høiby, Niels, Svendsen, J. S. M., Stensen, W., Thomsen, K., Cavanagh, J. P. & Moser, Claus Ernst, 2022, In: Journal of Global Antimicrobial Resistance. 29, p. 185-193 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Mucoid Pseudomonas aeruginosa isolates maintain the biofilm formation capacity and the gene expression profiles during the chronic lung infection of CF patients

      Lee, B., Schjerling, C. K., Kirkby, N., Hoffmann, N., Borup, R., Molin, S., Høiby, Niels & Ciofu, Oana, 2011, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 119, 4-5, p. 263-74 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Heterogeneity of biofilms formed by nonmucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis.

      Lee, B., Haagensen, J. A. J., Ciofu, Oana, Andersen, Jens Bo, Høiby, Niels & Molin, S., 2005, In: Journal of Clinical Microbiology. 43, 10, p. 5247-55 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Hyperbaric oxygen treatment augments tobramycin efficacy in experimental staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Kolpen, Mette, Nielsen, P. R., Trøstrup, H., Thomsen, K., Hyldegaard, Ole, Bundgård, Henning, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Antimicrobial Agents. 50, 3, p. 406-412

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Trøstrup, H., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Bundgaard, H., Høiby, Niels & Moser, C., 1 Dec 2015, In: European Journal of Clinical Microbiology & Infectious Diseases. 34, 12, p. 2349-2357 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Goetze, J. P., Nielsen, P. R., Thomsen, K., Enevold, C., Høiby, Niels, Jensen, Peter Østrup, Bundgård, Henning & Moser, Claus Ernst, 2019, In: PLoS ONE. 14, 4, 16 p., e0215333.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Anti-biofilm Approach in Infective Endocarditis Exposes New Treatment Strategies for Improved Outcome

      Lerche, C. J., Schwartz, F., Theut, M., Fosbøl, E. L., Iversen, Kasper, Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2021, In: Frontiers in Cell and Developmental Biology. 9, 25 p., 643335.

      Research output: Contribution to journalReviewResearchpeer-review

    30. Published

      Potential Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis

      Lerche, C. J., Schwartz, F., Pries-Heje, M. M., Fosbøl, E. L., Iversen, Kasper, Jensen, Peter Østrup, Høiby, Niels, Hyldegaard, Ole, Bundgård, Henning & Moser, Claus Ernst, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 805964.

      Research output: Contribution to journalReviewResearchpeer-review

    31. Published

      Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum

      Line, L., Alhede, M., Kolpen, Mette, Kühl, Michael, Ciofu, Oana, Bjarnsholt, Thomas, Moser, Claus Ernst, Toyofuku, M., Nomura, N., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Frontiers in Microbiology. 5, 11 p., 554.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Mycobacterium avium subspecies paratuberculosis

      Lisby, J. G. & Høiby, Niels, 2003, In: Ugeskrift for læger. 165(50), p. 4865-4866

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Mutator P. aeruginosa with Impaired Oxidative Repair System (mutT) forms thicker biofilms with increased tolerance to antibiotics compared to PAO1

      Mandsberg, L. F., Sternberg, C., Molin, S., Poulsen, Henrik Enghusen, Høiby, Niels & Ciofu, O., 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    34. Published

      Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system

      Mandsberg, L. F., Ciofu, Oana, Kirkby, N., Christiansen, L. E., Poulsen, Henrik Enghusen, Høiby, Niels, Mandsberg, L. F., Ciofu, O., Kirkby, N., Christiansen, L. E., Poulsen, Henrik Enghusen & Høiby, N., 1 Jun 2009, In: Antimicrobial Agents and Chemotherapy. 53, 6, p. 2483-91 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Development of antibiotic resistance and up-regulation of the antimutator gene pfpI in mutator Pseudomonas aeruginosa due to inactivation of two DNA oxidative repair genes (mutY, mutM)

      Mandsberg, L. F., Maciá, M. D., Bergmann, K. R., Christiansen, L., Alhede, M., Kirkby, N., Høiby, Niels, Oliver, A. & Ciofu, Oana, 2011, In: F E M S Microbiology Letters. 324, 1, p. 28-37 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Environmental Heterogeneity Drives Within-Host Diversification and Evolution of Pseudomonas aeruginosa

      Markussen, T., Marvig, R. L., Gómez-Lozano, M., Aanæs, K., Burleigh, A. E., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., 2014, In: mBio. 5, 5, p. 1-10 10 p., e01592-14.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa

      Marvig, R. L., Søndergaard, M. S. R., Damkiær, S., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., Aug 2012, In: Antimicrobial Agents and Chemotherapy. 56, 8, p. 4519-4521 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.

      Mathee, K., Ciofu, Oana, Sternberg, C., Lindum, P. W., Campbell, J. I., Jensen, P., Johnsen, A. H., Givskov, Michael, Ohman, D. E., Molin, S., Høiby, Niels & Kharazmi, A., 1999, In: Microbiology. 145 ( Pt 6), p. 1349-57 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Role of exopolysaccharide in biofilm matrix formation: The alginate paradigm

      Mathee, K., Kharazmi, A. & Høiby, Niels, 2002, Molecular Ecology of Biofilms. Wymondham, UK: Horizon Scientific Press, p. 1-34

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    40. Published

      Antibody response against Pseudomonas aeruginosa and its relationship with immune mediators in the upper and lower airways of cystic fibrosis patients

      Mauch, R. M., Hentschel, J., Aanæs, Kasper, Barucha, A., Nolasco da Silva, M. T., Levy, C. E., Høiby, Niels & Mainz, J. G., 2020, In: Pediatric Pulmonology. 55, 4, p. 959-967

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Secretory IgA response against Pseudomonas aeruginosa in the upper airways and the link with chronic lung infection in cystic fibrosis

      Mauch, R. M., Rossi, C. L., Aiello, T. B., Ribeiro, J. D., Ribeiro, A. F., Høiby, Niels & Levy, C. E., 2017, In: Pathogens and Disease. 75, 6, 4 p., ftx069.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Secretory IgA-mediated immune response in saliva and early detection of Pseudomonas aeruginosa in the lower airways of pediatric cystic fibrosis patients

      Mauch, R. M., Rossi, C. L., Nolasco da Silva, M. T., Bianchi Aiello, T., Ribeiro, J. D., Ribeiro, A. F., Høiby, Niels & Levy, C. E., 2019, In: Medical Microbiology and Immunology. 208, 2, p. 205-213 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Adaptive Immune Response to Mycobacterium abscessus Complex (MABSC) in Cystic Fibrosis and the Implications of Cross-Reactivity

      Mauch, R. M., Jensen, Peter Østrup, Qvist, T., Kolpen, M., Moser, Claus Ernst, Pressler, T., Nolasco da Silva, M. T., Høiby, Niels & Copenhagen Study Group on Mycobacterial Infections in Cystic Fibrosis, C. S. G. O. M. I. I. C. F., 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 858398.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis

      Mauch, R. M., Jensen, Peter Østrup, Moser, Claus Ernst, Levy, C. E. & Høiby, Niels, 2018, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17, 2, p. 143-152

      Research output: Contribution to journalReviewResearchpeer-review

    45. Published

      IgG avidity to Pseudomonas aeruginosa over the course of chronic lung biofilm infection in cystic fibrosis

      Mauch, R. M., Nørregaard, L. L., Ciofu, Oana, Levy, C. E. & Høiby, Niels, 2018, In: Journal of Cystic Fibrosis. 17, 3, p. 356-359

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Bakteriel meningitis i Danmark 2002 og 2003. Landsdaekkende registrering baseret på laboratoriedata

      Meyer, Christian, Schønheyder, H. C., Bangsborg, Jette Marie, Nielsen, X. C., Møller, J. K., Mølbak, K., Korshin, A., Rønneberg, E., Køster-Rasmussen, Rasmus, Høiby, Niels & Dansk Bakteriel Meningitis Gruppe, D. B. M. G., 2007, In: Ugeskrift for Laeger. 169, 6, p. 503-6 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Bakteriel meningitis i Danmark 2002 og 2003: Landsdækkende registrering baseret pa laboratoriedata

      Meyer, Christian, Schonheyder, H. C., Bangsborg, J., Nielsen, X. C., Moller, J. K., Molbak, K., Korshin, A., Ronneberg, E., Koster-Rasmussen, R. & Høiby, Niels, 2007, In: Ugeskrift for læger. 169, 6, p. 503-506 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Staphylococcus aureus alters growth activity, autolysis and antibiotic tolerance in a human host-adapted Pseudomonas aeruginosa lineage

      Michelsen, C. F., Christensen, A. J., Bojer, Martin Saxtorph, Høiby, Niels, Ingmer, Hanne & Jelsbak, L., 2014, In: Journal of Bacteriology. 196, 22, p. 3903-3911 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients

      Miller, A. K., Brannon, M. K., Stevens, L., Johansen, Helle Krogh, Selgrade, S. E., Miller, S. I., Høiby, Niels & Moskowitz, S. M., 3 Oct 2011, In: Antimicrobial Agents and Chemotherapy. 55, 12, p. 5761-5769

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients

      Molchanova, N., Wang, H., Hansen, Paul Robert, Høiby, Niels, Nielsen, Hanne Mørck & Franzyk, Henrik, 2019, In: Frontiers in Microbiology. 10, 9 p., 275.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      The immune response to chronic Pseudomonas aeruginosa lung infection in cystic fibrosis patients is predominantly of the Th2 type

      Moser, C., Kjaergaard, S., Pressler, T., Kharazmi, A., Koch, C. & Høiby, Niels, 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 5, p. 329-35 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Early immune response in susceptible and resistant mice strains with chronic Pseudomonas aeruginosa lung infection determines the type of T-helper cell response

      Moser, C., Hougen, H. P., Song, Z., Rygaard, J., Kharazmi, A. & Høiby, Niels, 1999, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 107, 12, p. 1093-100 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      Selective recruitment of Th I cells induced by re-infection of succeptible and resistant mice with Pseudomonas aerugionosa in the lungs indicates protective role of IL-12.

      Moser, Claus Ernst, Jensen, Peter Østrup, Kobayashi, O., Hougen, H. P., Song, Z., Rygaard, J., Kharazmi, A. & Høiby, Niels, 2002, In: Clinical and Experimental Immunology. 127, 2, p. 206-213 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Published

      Improved outcome of chronic Pseudomonas aeruginosa lung infection is associated with induction of a Th1-dominated cytokine response

      Moser, C., Jensen, P. O., Kobayashi, O., Hougen, H. P., Song, Z., Rygaard, J., Kharazmi, A. & Høiby, Niels, 1 Feb 2002, In: Clinical and Experimental Immunology. 127, 2, p. 206-213 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. Published

      Chronic Pseudomonas aeruginosa lung infection is more severe in Th2 responding BALB/c mice compared to Th1 responding C3H/HeN mice

      Moser, Claus Ernst, Johansen, Helle Krogh, Song, Z., Hougen, H. P., Rygaard, J. & Høiby, Niels, 1997, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 105, 11, p. 838-42 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. Published

      Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis

      Moser, C., Gennip, M. V., Bjarnsholt, Thomas, Jensen, Peter Østrup, Lee, B., Hougen, H. P., Calum, H., Ciofu, Oana, Givskov, Michael, Molin, S. & Høiby, Niels, 1 Feb 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 2, p. 95-107 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. Published

      The immune response to chronic Pseudomonas aeruginosa lung infection in cystic fibrosis patients is predominantly of a Th2 type

      Moser, C., Kjærgaard, S., Pressler, T., Kharazmi, A., Koch, C. & Høiby, Niels, 2000, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 108, p. 329-335

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Next generation microbiology and cystic fibrosis diagnostics: are we there yet?

      Moser, Claus Ernst, Thomsen, T. R. & Høiby, Niels, 2018, In: Current Opinion in Pulmonary Medicine. 24, 6, p. 599-605

      Research output: Contribution to journalReviewResearchpeer-review

    59. Published

      Nye retningslinjer for antibiotikadosering til patienter med nedsat nyrefunktion og patienter i haemodialyse

      Moser, C., Elung-Jensen, T. & Høiby, Niels, 2008, In: Ugeskrift for læger. 170, 8, p. 629-32 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    60. Published

      Editorial comment

      Moser, Claus Ernst, Song, Z. & Høiby, Niels, 2019, In: APMIS. 127, 5, 1 p.

      Research output: Contribution to journalEditorialResearchpeer-review

    61. Published

      Forøget renal udskillelse af antibiotika kan resultere i underdosering ved sepsis

      Moser, Claus Ernst, Hartvig, T., Schierbeck, J. & Høiby, Niels, 2016, In: Ugeskrift for Laeger. 178, p. 2-6 5 p., V05150426.

      Research output: Contribution to journalJournal articleResearchpeer-review

    62. Published

      Antibiotic therapy as personalized medicine - general considerations and complicating factors

      Moser, Claus Ernst, Lerche, C. J., Thomsen, K., Hartvig, T., Schierbeck, J., Jensen, Peter Østrup, Ciofu, Oana & Høiby, Niels, 2019, In: APMIS. 127, 5, p. 361-371

      Research output: Contribution to journalReviewResearchpeer-review

    63. Published

      Serum concentrations of GM-CSF and G-CSF correlate with the Th1/Th2 cytokine response in cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

      Moser, Claus Ernst, Jensen, Peter Østrup, Pressler, T., Frederiksen, B., Lanng, S., Kharazmi, A., Koch, C. & Høiby, Niels, Jun 2005, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 113, 6, p. 400-9 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    64. Published

      Biofilms and host response - helpful or harmful

      Moser, Claus Ernst, Pedersen, H. T., Lerche, C. J., Kolpen, Mette, Line, L., Thomsen, K., Høiby, Niels & Jensen, Peter Østrup, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 320-338 19 p.

      Research output: Contribution to journalReviewResearchpeer-review

    65. Published

      Novel experimental Pseudomonas aeruginosa infection model mimicking long-term host-pathogen interactions in cystic fibrosis.

      Moser, Claus Ernst, van Gennip, M., Bjarnsholt, Thomas, Jensen, P. Ø., Lee, B., Hougen, H. P., Calum, Henrik Pierre, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2009, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 117, p. 95-107 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    66. Published

      PmrB Mutations Promote Polymyxin Resistance of Pseudomonas aeruginosa Isolated from Colistin-Treated Cystic Fibrosis Patients

      Moskowitz, S. M., Brannon, M. K., Dasgupta, N., Pier, M., Sgambati, N., Miller, A. K., Selgrade, S. E., Miller, S. I., Denton, M., Conway, S. P., Johansen, Helle Krogh & Høiby, Niels, Feb 2012, In: Antimicrobial Agents and Chemotherapy. 56, 2, p. 1019-1030 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    67. Published

      Sinus bacteriology in patients with cystic fibrosis or primary ciliary dyskinesia: A systematic review

      Møller, M. E., Alanin, M. C., Grønhøj, C., Aanæs, Kasper, Høiby, Niels & von Buchwald, Christian, 2017, In: American Journal of Rhinology and Allergy. 31, 5, p. 293-298 6 p.

      Research output: Contribution to journalReviewResearchpeer-review

    68. Published

      Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients

      Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664

      Research output: Contribution to journalJournal articleResearchpeer-review

    69. Published

      New technology markedly improves hand-hygiene performance among healthcare workers after restroom visits

      Møller-Sørensen, H., Korshin, A., Mogensen, T. & Høiby, Niels, Apr 2016, In: Journal of Hospital Infection. 92, 4, p. 337-339 3 p.

      Research output: Contribution to journalLetterResearchpeer-review

    70. Published

      Susceptibility of Legionella species to five antibiotics and development of resistance by exposure to erythromycin, ciproflocxacin, and rifampicin

      Nielsen, K., Bangsborg, Jette Marie & Høiby, Niels, 2000, In: Diagnostic Microbiology and Infectious Disease. 36, p. 43-48

      Research output: Contribution to journalJournal articleResearchpeer-review

    71. Published

      Sequencing of the rpoB gene in Legionella pneumophila and characterization of mutations associated with rifampicin resistance in the Legionellaceae

      Nielsen, K., Hindersson, P., Høiby, Niels & Bangsborg, Jette Marie, 2000, In: Antimicrobial Agents and Chemotherapy. 44, p. 2679-2683

      Research output: Contribution to journalJournal articleResearchpeer-review

    72. Published

      The dlt genes play a role in antimicrobial tolerance of Streptococcus mutans biofilms

      Nilsson, Carl Martin Peter, Rybtke, Morten Levin, Givskov, Michael, Høiby, Niels, Twetman, Svante & Tolker-Nielsen, Tim, Sep 2016, In: International Journal of Antimicrobial Agents. 48, 3, p. 298–304

      Research output: Contribution to journalJournal articleResearchpeer-review

    73. Published

      A mariner transposon vector adapted for mutagenesis in oral streptococci

      Nilsson, M., Christiansen, N., Høiby, Niels, Twetman, Svante, Givskov, Michael & Tolker-Nielsen, Tim, Jun 2014, In: MicrobiologyOpen. 3, 3, p. 333-40 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    74. Published

      Genome sequence of Pseudomonas aeruginosa strain DK1-NH57388A, a stable mucoid cystic fibrosis isolate

      Norman, A., Ciofu, Oana, Amador, C. I., Høiby, Niels & Jelsbak, L., 2016, In: Genome Announcements. 4, 1, e00008-16.

      Research output: Contribution to journalJournal articleResearch

    75. Published

      Unusual distribution of Burkholderia cepacia complex species in Danish cystic fibrosis clinics may stem from restricted transmission between patients

      Nørskov-Lauritsen, N., Johansen, Helle Krogh, Fenger, M. G., Nielsen, X. C., Pressler, T., Olesen, H. V. & Høiby, Niels, 1 Aug 2010, In: Journal of Clinical Microbiology. 48, 8, p. 2981-3 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    76. Published

      Prehospital diagnostic and therapeutic management of otogenic Streptococcus pneumoniae meningitis

      Ostergaard, C., Høiby, Niels, Konradsen, H. B. & Samuelsson, S., 2006, In: Scandinavian Journal of Infectious Diseases. 38, 3, p. 172-180 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    77. Published

      Alginate in infection

      Pedersen, S. S., Høiby, Niels, Espersen, F. & Kharazmi, A., 1991, In: Antibiotics and Chemotherapy. 44, p. 68-79 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    78. Published

      Diagnostik ved infektionssygdomme. Nocardiosis

      Permin, H. & Høiby, Niels, 2002, In: Ugeskrift for læger. 164, p. 883

      Research output: Contribution to journalJournal articleResearchpeer-review

    79. Published

      Diagnostik ved infektionssygdomme

      Permin, H. & Høiby, Niels, 2001, In: Ugeskrift for læger. 163, p. 2657-2658

      Research output: Contribution to journalJournal articleResearchpeer-review

    80. Published

      Diagnostik ved infektionssygdomme. Meningitis

      Permin, H., Moser, C. & Høiby, Niels, 2001, In: Ugeskrift for læger. 163, p. 4174-4175

      Research output: Contribution to journalJournal articleResearchpeer-review

    81. Published

      Diagnostik ved infektionssygdomme. Pneumoni

      Permin, H., Johansen, Helle Krogh & Høiby, Niels, 2001, In: Ugeskrift for læger. 163, p. 6259-6260

      Research output: Contribution to journalJournal articleResearchpeer-review

    82. Published

      Diagnostik ved infektionssygdomme. Hjerneabsces

      Permin, H. & Høiby, Niels, 2002, In: Ugeskrift for læger. 164, p. 749-750

      Research output: Contribution to journalJournal articleResearchpeer-review

    83. Published

      Diagnostik ved infektionssygdomme. Actinomycosis

      Permin, H. & Høiby, Niels, 2002, In: Ugeskrift for læger. 164, p. 1195-1196

      Research output: Contribution to journalJournal articleResearchpeer-review

    84. Published

      Quantitative analysis of the IgG and IgG subclass immune responses to chromosomal Pseudomonas aeruginosa beta-lactamase in serum from patients with cystic fibrosis by western blotting and laser scanning densitometry.

      Petersen, T. D., Ciofu, Oana, Pressler, T., Giwercman, B., Pedersen, S. S. & Høiby, Niels, 1996, In: Thorax. 51, 7, p. 733-8 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    85. Published

      Effects of Photoactivated Titanium Dioxide Nanopowders and Coating on Planktonic and Biofilm Growth of Pseudomonas aeruginosa

      Polo, A., Diamanti, M. V., Bjarnsholt, Thomas, Høiby, Niels, Villa, F., Pedeferri, M. P. & Cappitelli, F., 25 Jul 2011, In: Photochemistry and Photobiology.

      Research output: Contribution to journalJournal articleResearchpeer-review

    86. Published

      Chronic Pseudomonas aeruginosa infection definition: EuroCareCF Working Group report

      Pressler, T., Bohmova, C., Conway, S., Dumcius, S., Hjelte, L., Høiby, Niels, Kollberg, H., Tümmler, B. & Vavrova, V., 1 Jun 2011, In: Journal of Cystic Fibrosis. 10 Suppl 2, p. S75-8

      Research output: Contribution to journalJournal articleResearchpeer-review

    87. Published

      Diagnostic significance of measurements of specific IgG antibodies to Pseudomonas aeruginosa by three different serological methods

      Pressler, T., Karpati, F., Granstrom, M., Knudsen, P. K., Lindblad, A., Hjelte, L., Olesen, H. V., Meyer, P. & Høiby, Niels, 2008, In: Journal of Cystic Fibrosis. 8, 1, p. 37-42 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    88. Published

      Early rise of anti-pseudomonas antibodies and a mucoid phenotype of pseudomonas aeruginosa are risk factors for development of chronic lung infection--a case control study

      Pressler, T., Frederiksen, B., Skov, M., Garred, P., Koch, C. & Høiby, Niels, 2006, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 5, 1, p. 9-15 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    89. Published

      Early rise of anti-Pseudomonas antibodies and a mucoid phenotype of Pseudomonas aeruginosa are risk factors for development of chronic lung infection - A case control study (vol 5, pg 9, 2006)

      Pressler, T., Frederiksen, B., Skov, M., Garred, Peter, Koch, C. & Høiby, Niels, 2007, In: Journal of Cystic Fibrosis. 6, 1, p. 79-79

      Research output: Contribution to journalJournal articleResearchpeer-review

    90. Published

      IMPACT OF EARLY AGGRESSIVE ANTIBIOTIC ERADICATION THERAPY FOR RESPIRATORY

      Pressler, T., Nielsen, K. G. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    91. Published

      Evaluating the "Leeds criteria'' for Pseudomonas aeruginosa infection in a cystic fibrosis centre

      Proesmans, M., Balinska-Miskiewicz, W., Dupont, L., Bossuyt, X., Verhaegen, J., Høiby, Niels & Boeck, K. D., 2006, In: European Respiratory Journal. 27, 5, p. 937-943 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    92. Published

      Chronic pulmonary disease with Mycobacterium abscessus complex is a biofilm infection

      Qvist, T., Eickhardt-Dalbøge, S. R., Kragh, K. N., Andersen, C. B., Iversen, M., Høiby, Niels & Bjarnsholt, Thomas, Dec 2015, In: European Respiratory Journal. 46, 6, p. 1823-1826 4 p.

      Research output: Contribution to journalComment/debateResearchpeer-review

    93. Published

      Shifting paradigms of nontuberculous mycobacteria in cystic fibrosis

      Qvist, T., Pressler, T., Høiby, Niels & Katzenstein, T. L., 2014, In: Respiratory research. 15, p. 1-6 6 p., 41.

      Research output: Contribution to journalComment/debateResearch

    94. Published

      Urine lipoarabinomannan point-of-care testing in patients affected by pulmonary nontuberculous mycobacteria - experiences from the Danish Cystic Fibrosis cohort study

      Qvist, T., Johansen, I. S., Pressler, T., Høiby, Niels, Andersen, A. B., Katzenstein, T. L. & Bjerrum, S., 4 Dec 2014, In: BMC Infectious Diseases. 14, p. 1-8 8 p., 655.

      Research output: Contribution to journalJournal articleResearchpeer-review

    95. Published

      Evaluation of a bovine antibody test for diagnosing Mycobacterium avium complex in patients with cystic fibrosis

      Qvist, T., Pressler, T., Katzenstein, T. L., Høiby, Niels & Collins, M. T., Jan 2017, In: Pediatric Pulmonology. 52, 1, p. 34-40 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    96. Published

      Dietzia papillomatosis Bacteremia

      Rammer, P., Calum, Henrik Pierre, Moser, Claus Ernst, Björnsdóttir, M. K., Smedegaard, H., Høiby, Niels & Bjarnsholt, Thomas, Jun 2013, In: Journal of Clinical Microbiology. 51, 6, p. 1977-8 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    97. Published

      Terminal truncations in Amp C beta-lactamase from a clinical isolate of Pseudomonas aeruginosa

      Rasmussen, J. W., Johnsen, A. H. & Høiby, Niels, 1999, In: European Journal of Biochemistry. 263, p. 478-485

      Research output: Contribution to journalJournal articleResearchpeer-review

    98. Published
    99. Published

      SARS-CoV-2 infection dynamics in Denmark, February through October 2020: Nature of the past epidemic and how it may develop in the future

      Rasmussen, S., Petersen, M. S. & Høiby, Niels, 2021, In: PLoS ONE. 16, 4 April, e0249733.

      Research output: Contribution to journalJournal articleResearchpeer-review

    100. Published

      Identity and effects of quorum-sensing inhibitors produced by Penicillium species

      Rasmussen, T. B., Skindersoe, M. E., Bjarnsholt, T., Phipps, R. K., Christensen, K. B., Jensen, Peter Østrup, Andersen, Jens Bo, Koch, B., Larsen, T. O., Hentzer, M., Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: Microbiology. 151, Pt 5, p. 1325-40 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 8427