Niels Høiby
Professor, No job title
Bacteriology
Blegdamsvej 3B, 2200 København N, 24 Bygning 24, Building: 24-1-16
Member of:
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Diagnosis and treatment of cystic fibrosis
Koch, C. & Høiby, Niels, 2000, In: Tanaffos. 67, p. 239-247Research output: Contribution to journal › Journal article › Research › peer-review
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O-2 AFFECTS THE ACTIVITY OF AMIKACIN ON MYCOBACTERIUM ABSCESSUS BIOFILM
Kolpen, M., Ravnholt, C., Qvist, T., Kragh, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, Sep 2017, In: Pediatric Pulmonology. 52, S47, p. S359-S360 379.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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RE-SENSITIZATION OF ANOXIC PSEUDOMONAS AERUGINOSA BIOFILMS WITH RE-OXYGENATION USING HYPERBARIC OXYGEN TREATMENT
Kolpen, Mette, Mousavi, N., Sams, T., Kragh, K. N., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, P. O., Oct 2015, In: Pediatric Pulmonology. 50, S41, p. 312-312 1 p., 322.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment
Kolpen, Mette, Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin
Kolpen, Mette, Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.Research output: Contribution to journal › Journal article › Research › peer-review
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Nitric oxide production by polymorphonuclear leukocytes in sputum from cystic fibrosis patients with chronic lung infection
Kolpen, Mette, Bjarnsholt, Thomas, Moser, C., Hansen, C. R., Kühl, Michael, Høiby, Niels & Jensen, P. Ø., 2010, In: Journal of Cystic Fibrosis. Supplement 1, p. S49 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Nitric oxide production by polymorphonuclear leukocytes in sputum from cystic fibrosis patients with chronic lung infection
Kolpen, M., Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Kühl, M., Høiby, Niels & Jensen, Peter Østrup, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Nitric oxide production by polymorphonuclear leukocytes in infected cystic fibrosis sputum consumes oxygen
Kolpen, Mette, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Rickelt, L. F., Kühl, Michael, Hempel, C., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Clinical and Experimental Immunology. 177, 1, p. 310–319 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Denitrification by cystic fibrosis pathogens - Stenotrophomonas maltophilia is dormant in sputum
Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas, Line, L., Hansen, C. R., Dalbøge, C. S., Hansen, N., Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2015, In: International Journal of Medical Microbiology. 305, 1, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
Kolpen, Mette, Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Liengaard, L., Kharazmi, A., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: PLOS ONE. 9, 1, p. e84353 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis
Kolpen, Mette, Hansen, C. R., Bjarnsholt, Thomas, Moser, C., Hultqvist, Louise Dahl, van Gennip, M., Ciofu, Oana, Mandsberg, L., Kharazmi, A., Döring, G., Givskov, Michael, Høiby, Niels & Jensen, Peter Østrup, 1 Jan 2010, In: Thorax. 65, 1, p. 57-62 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation
Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions
Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.Research output: Contribution to journal › Journal article › Research › peer-review
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Anaerobic bacteria in biofilm –and their tolerance to antibiotics
Kragh, K. N., Kühl, Michael, Gregersen, A., Tvede, M., Høiby, Niels & Bjarnsholt, Thomas, 2011.Research output: Contribution to conference › Poster › Research
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Polymorphonuclear leukocytes restrict growth of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients
Kragh, K. N., Alhede, M., Jensen, Peter Østrup, Moser, Claus Ernst, Scheike, Thomas, Jacobsen, C. S., Poulsen, Steen Seier, Eickhardt-Sørensen, S. R., Trostrup, H., Christoffersen, L., Hougen, H. P., Rickelt, L. F., Kühl, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2014, In: Infection and Immunity. 82, 11, p. 4477-4486 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Induction of oxidative burst response in human neutrophils by immune complexes made in vitro of lipopolysaccharide and hyperimmune serum from chronically infected patients
Kronborg, Gitte, Fomsgaard, A., Jensen, E. T., Kharazmi, A. & Høiby, Niels, 1993, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 101, 11, p. 887-94 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Experimental chronic Pseudomonas aeruginosa lung infection in rats. Non-specific stimulation with LPS reduces lethality as efficiently as specific immunization
Lange, Kai, Hougen, H. P., Høiby, Niels, Fomsgaard, A., Rygaard, J. & Johansen, Helle Krogh, 1995, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 103, 5, p. 367-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kolera i Danmark--et importeret sygdomstilfoelde
Lange, Kai, Pedersen, K. M., Nielsen, S. E. & Høiby, Niels, 17 Apr 1995, In: Ugeskrift for Laeger. 157, 16, p. 2325-6 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Use of cultivation-dependent and -independent techniques to assess contamination of central venous catheters: a pilot study
Larsen, M. K., Thomsen, T. R., Moser, C., Nielsen, P. H. & Høiby, Niels, 2008, In: BMC Clinical Pathology. 8, p. 10 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adjunctive S100A8/A9 Immunomodulation Hinders Ciprofloxacin Resistance in Pseudomonas aeruginosa in a Murine Biofilm Wound Model
Laulund, A. S., Schwartz, F., Trøstrup, H., Thomsen, K., Christophersen, L., Calum, Henrik Pierre, Ciofu, Oana, Høiby, Niels & Moser, Claus Ernst, 2021, In: Frontiers in Cellular and Infection Microbiology. 11, 652012.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperbaric oxygen therapy augments ciprofloxacin effect against Pseudomonas aeruginosa biofilm infected chronic wounds in a mouse model
Laulund, A. S., Schwartz, F. A., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Calum, Henrik Pierre, Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 5, 100100.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperbaric oxygen therapy counteracts Pseudomonas aeruginosa biofilm micro-compartment phenomenon in murine thermal wounds
Laulund, A. S., Schwartz, F. A., Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 6, 8 p., 100159.Research output: Contribution to journal › Journal article › Research › peer-review
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Lactoferricin-inspired peptide AMC-109 augments the effect of ciprofloxacin against Pseudomonas aeruginosa biofilm in chronic murine wounds
Laulund, A. S., Schwartz, F. A., Christophersen, L., Høiby, Niels, Svendsen, J. S. M., Stensen, W., Thomsen, K., Cavanagh, J. P. & Moser, Claus Ernst, 2022, In: Journal of Global Antimicrobial Resistance. 29, p. 185-193 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mucoid Pseudomonas aeruginosa isolates maintain the biofilm formation capacity and the gene expression profiles during the chronic lung infection of CF patients
Lee, B., Schjerling, C. K., Kirkby, N., Hoffmann, N., Borup, R., Molin, S., Høiby, Niels & Ciofu, Oana, 2011, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 119, 4-5, p. 263-74 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterogeneity of biofilms formed by nonmucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis.
Lee, B., Haagensen, J. A. J., Ciofu, Oana, Andersen, Jens Bo, Høiby, Niels & Molin, S., 2005, In: Journal of Clinical Microbiology. 43, 10, p. 5247-55 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperbaric oxygen treatment augments tobramycin efficacy in experimental staphylococcus aureus endocarditis
Lerche, C. J., Christophersen, L. J., Kolpen, Mette, Nielsen, P. R., Trøstrup, H., Thomsen, K., Hyldegaard, Ole, Bundgård, Henning, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Antimicrobial Agents. 50, 3, p. 406-412Research output: Contribution to journal › Journal article › Research › peer-review
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Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis
Lerche, C. J., Christophersen, L. J., Trøstrup, H., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Bundgaard, H., Høiby, Niels & Moser, C., 1 Dec 2015, In: European Journal of Clinical Microbiology & Infectious Diseases. 34, 12, p. 2349-2357 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis
Lerche, C. J., Christophersen, L. J., Goetze, J. P., Nielsen, P. R., Thomsen, K., Enevold, C., Høiby, Niels, Jensen, Peter Østrup, Bundgård, Henning & Moser, Claus Ernst, 2019, In: PLoS ONE. 14, 4, 16 p., e0215333.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-biofilm Approach in Infective Endocarditis Exposes New Treatment Strategies for Improved Outcome
Lerche, C. J., Schwartz, F., Theut, M., Fosbøl, E. L., Iversen, Kasper, Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2021, In: Frontiers in Cell and Developmental Biology. 9, 25 p., 643335.Research output: Contribution to journal › Review › Research › peer-review
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Potential Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis
Lerche, C. J., Schwartz, F., Pries-Heje, M. M., Fosbøl, E. L., Iversen, Kasper, Jensen, Peter Østrup, Høiby, Niels, Hyldegaard, Ole, Bundgård, Henning & Moser, Claus Ernst, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 805964.Research output: Contribution to journal › Review › Research › peer-review
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
Line, L., Alhede, M., Kolpen, Mette, Kühl, Michael, Ciofu, Oana, Bjarnsholt, Thomas, Moser, Claus Ernst, Toyofuku, M., Nomura, N., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Frontiers in Microbiology. 5, 11 p., 554.Research output: Contribution to journal › Journal article › Research › peer-review
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Mycobacterium avium subspecies paratuberculosis
Lisby, J. G. & Høiby, Niels, 2003, In: Ugeskrift for læger. 165(50), p. 4865-4866Research output: Contribution to journal › Journal article › Research › peer-review
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Mutator P. aeruginosa with Impaired Oxidative Repair System (mutT) forms thicker biofilms with increased tolerance to antibiotics compared to PAO1
Mandsberg, L. F., Sternberg, C., Molin, S., Poulsen, Henrik Enghusen, Høiby, Niels & Ciofu, O., 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system
Mandsberg, L. F., Ciofu, Oana, Kirkby, N., Christiansen, L. E., Poulsen, Henrik Enghusen, Høiby, Niels, Mandsberg, L. F., Ciofu, O., Kirkby, N., Christiansen, L. E., Poulsen, Henrik Enghusen & Høiby, N., 1 Jun 2009, In: Antimicrobial Agents and Chemotherapy. 53, 6, p. 2483-91 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of antibiotic resistance and up-regulation of the antimutator gene pfpI in mutator Pseudomonas aeruginosa due to inactivation of two DNA oxidative repair genes (mutY, mutM)
Mandsberg, L. F., Maciá, M. D., Bergmann, K. R., Christiansen, L., Alhede, M., Kirkby, N., Høiby, Niels, Oliver, A. & Ciofu, Oana, 2011, In: F E M S Microbiology Letters. 324, 1, p. 28-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Environmental Heterogeneity Drives Within-Host Diversification and Evolution of Pseudomonas aeruginosa
Markussen, T., Marvig, R. L., Gómez-Lozano, M., Aanæs, K., Burleigh, A. E., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., 2014, In: mBio. 5, 5, p. 1-10 10 p., e01592-14.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa
Marvig, R. L., Søndergaard, M. S. R., Damkiær, S., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., Aug 2012, In: Antimicrobial Agents and Chemotherapy. 56, 8, p. 4519-4521 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.
Mathee, K., Ciofu, Oana, Sternberg, C., Lindum, P. W., Campbell, J. I., Jensen, P., Johnsen, A. H., Givskov, Michael, Ohman, D. E., Molin, S., Høiby, Niels & Kharazmi, A., 1999, In: Microbiology. 145 ( Pt 6), p. 1349-57 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of exopolysaccharide in biofilm matrix formation: The alginate paradigm
Mathee, K., Kharazmi, A. & Høiby, Niels, 2002, Molecular Ecology of Biofilms. Wymondham, UK: Horizon Scientific Press, p. 1-34Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Antibody response against Pseudomonas aeruginosa and its relationship with immune mediators in the upper and lower airways of cystic fibrosis patients
Mauch, R. M., Hentschel, J., Aanæs, Kasper, Barucha, A., Nolasco da Silva, M. T., Levy, C. E., Høiby, Niels & Mainz, J. G., 2020, In: Pediatric Pulmonology. 55, 4, p. 959-967Research output: Contribution to journal › Journal article › Research › peer-review
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Secretory IgA response against Pseudomonas aeruginosa in the upper airways and the link with chronic lung infection in cystic fibrosis
Mauch, R. M., Rossi, C. L., Aiello, T. B., Ribeiro, J. D., Ribeiro, A. F., Høiby, Niels & Levy, C. E., 2017, In: Pathogens and Disease. 75, 6, 4 p., ftx069.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretory IgA-mediated immune response in saliva and early detection of Pseudomonas aeruginosa in the lower airways of pediatric cystic fibrosis patients
Mauch, R. M., Rossi, C. L., Nolasco da Silva, M. T., Bianchi Aiello, T., Ribeiro, J. D., Ribeiro, A. F., Høiby, Niels & Levy, C. E., 2019, In: Medical Microbiology and Immunology. 208, 2, p. 205-213 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adaptive Immune Response to Mycobacterium abscessus Complex (MABSC) in Cystic Fibrosis and the Implications of Cross-Reactivity
Mauch, R. M., Jensen, Peter Østrup, Qvist, T., Kolpen, M., Moser, Claus Ernst, Pressler, T., Nolasco da Silva, M. T., Høiby, Niels & Copenhagen Study Group on Mycobacterial Infections in Cystic Fibrosis, C. S. G. O. M. I. I. C. F., 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 858398.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis
Mauch, R. M., Jensen, Peter Østrup, Moser, Claus Ernst, Levy, C. E. & Høiby, Niels, 2018, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17, 2, p. 143-152Research output: Contribution to journal › Review › Research › peer-review
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IgG avidity to Pseudomonas aeruginosa over the course of chronic lung biofilm infection in cystic fibrosis
Mauch, R. M., Nørregaard, L. L., Ciofu, Oana, Levy, C. E. & Høiby, Niels, 2018, In: Journal of Cystic Fibrosis. 17, 3, p. 356-359Research output: Contribution to journal › Journal article › Research › peer-review
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Bakteriel meningitis i Danmark 2002 og 2003. Landsdaekkende registrering baseret på laboratoriedata
Meyer, Christian, Schønheyder, H. C., Bangsborg, Jette Marie, Nielsen, X. C., Møller, J. K., Mølbak, K., Korshin, A., Rønneberg, E., Køster-Rasmussen, Rasmus, Høiby, Niels & Dansk Bakteriel Meningitis Gruppe, D. B. M. G., 2007, In: Ugeskrift for Laeger. 169, 6, p. 503-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bakteriel meningitis i Danmark 2002 og 2003: Landsdækkende registrering baseret pa laboratoriedata
Meyer, Christian, Schonheyder, H. C., Bangsborg, J., Nielsen, X. C., Moller, J. K., Molbak, K., Korshin, A., Ronneberg, E., Koster-Rasmussen, R. & Høiby, Niels, 2007, In: Ugeskrift for læger. 169, 6, p. 503-506 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Staphylococcus aureus alters growth activity, autolysis and antibiotic tolerance in a human host-adapted Pseudomonas aeruginosa lineage
Michelsen, C. F., Christensen, A. J., Bojer, Martin Saxtorph, Høiby, Niels, Ingmer, Hanne & Jelsbak, L., 2014, In: Journal of Bacteriology. 196, 22, p. 3903-3911 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients
Miller, A. K., Brannon, M. K., Stevens, L., Johansen, Helle Krogh, Selgrade, S. E., Miller, S. I., Høiby, Niels & Moskowitz, S. M., 3 Oct 2011, In: Antimicrobial Agents and Chemotherapy. 55, 12, p. 5761-5769Research output: Contribution to journal › Journal article › Research › peer-review
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Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients
Molchanova, N., Wang, H., Hansen, Paul Robert, Høiby, Niels, Nielsen, Hanne Mørck & Franzyk, Henrik, 2019, In: Frontiers in Microbiology. 10, 9 p., 275.Research output: Contribution to journal › Journal article › Research › peer-review
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The immune response to chronic Pseudomonas aeruginosa lung infection in cystic fibrosis patients is predominantly of the Th2 type
Moser, C., Kjaergaard, S., Pressler, T., Kharazmi, A., Koch, C. & Høiby, Niels, 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 5, p. 329-35 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early immune response in susceptible and resistant mice strains with chronic Pseudomonas aeruginosa lung infection determines the type of T-helper cell response
Moser, C., Hougen, H. P., Song, Z., Rygaard, J., Kharazmi, A. & Høiby, Niels, 1999, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 107, 12, p. 1093-100 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selective recruitment of Th I cells induced by re-infection of succeptible and resistant mice with Pseudomonas aerugionosa in the lungs indicates protective role of IL-12.
Moser, Claus Ernst, Jensen, Peter Østrup, Kobayashi, O., Hougen, H. P., Song, Z., Rygaard, J., Kharazmi, A. & Høiby, Niels, 2002, In: Clinical and Experimental Immunology. 127, 2, p. 206-213 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improved outcome of chronic Pseudomonas aeruginosa lung infection is associated with induction of a Th1-dominated cytokine response
Moser, C., Jensen, P. O., Kobayashi, O., Hougen, H. P., Song, Z., Rygaard, J., Kharazmi, A. & Høiby, Niels, 1 Feb 2002, In: Clinical and Experimental Immunology. 127, 2, p. 206-213 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chronic Pseudomonas aeruginosa lung infection is more severe in Th2 responding BALB/c mice compared to Th1 responding C3H/HeN mice
Moser, Claus Ernst, Johansen, Helle Krogh, Song, Z., Hougen, H. P., Rygaard, J. & Høiby, Niels, 1997, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 105, 11, p. 838-42 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis
Moser, C., Gennip, M. V., Bjarnsholt, Thomas, Jensen, Peter Østrup, Lee, B., Hougen, H. P., Calum, H., Ciofu, Oana, Givskov, Michael, Molin, S. & Høiby, Niels, 1 Feb 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 2, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The immune response to chronic Pseudomonas aeruginosa lung infection in cystic fibrosis patients is predominantly of a Th2 type
Moser, C., Kjærgaard, S., Pressler, T., Kharazmi, A., Koch, C. & Høiby, Niels, 2000, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 108, p. 329-335Research output: Contribution to journal › Journal article › Research › peer-review
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Next generation microbiology and cystic fibrosis diagnostics: are we there yet?
Moser, Claus Ernst, Thomsen, T. R. & Høiby, Niels, 2018, In: Current Opinion in Pulmonary Medicine. 24, 6, p. 599-605Research output: Contribution to journal › Review › Research › peer-review
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Nye retningslinjer for antibiotikadosering til patienter med nedsat nyrefunktion og patienter i haemodialyse
Moser, C., Elung-Jensen, T. & Høiby, Niels, 2008, In: Ugeskrift for læger. 170, 8, p. 629-32 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Editorial comment
Moser, Claus Ernst, Song, Z. & Høiby, Niels, 2019, In: APMIS. 127, 5, 1 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Forøget renal udskillelse af antibiotika kan resultere i underdosering ved sepsis
Moser, Claus Ernst, Hartvig, T., Schierbeck, J. & Høiby, Niels, 2016, In: Ugeskrift for Laeger. 178, p. 2-6 5 p., V05150426.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibiotic therapy as personalized medicine - general considerations and complicating factors
Moser, Claus Ernst, Lerche, C. J., Thomsen, K., Hartvig, T., Schierbeck, J., Jensen, Peter Østrup, Ciofu, Oana & Høiby, Niels, 2019, In: APMIS. 127, 5, p. 361-371Research output: Contribution to journal › Review › Research › peer-review
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Serum concentrations of GM-CSF and G-CSF correlate with the Th1/Th2 cytokine response in cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
Moser, Claus Ernst, Jensen, Peter Østrup, Pressler, T., Frederiksen, B., Lanng, S., Kharazmi, A., Koch, C. & Høiby, Niels, Jun 2005, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 113, 6, p. 400-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biofilms and host response - helpful or harmful
Moser, Claus Ernst, Pedersen, H. T., Lerche, C. J., Kolpen, Mette, Line, L., Thomsen, K., Høiby, Niels & Jensen, Peter Østrup, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 320-338 19 p.Research output: Contribution to journal › Review › Research › peer-review
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Novel experimental Pseudomonas aeruginosa infection model mimicking long-term host-pathogen interactions in cystic fibrosis.
Moser, Claus Ernst, van Gennip, M., Bjarnsholt, Thomas, Jensen, P. Ø., Lee, B., Hougen, H. P., Calum, Henrik Pierre, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2009, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 117, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PmrB Mutations Promote Polymyxin Resistance of Pseudomonas aeruginosa Isolated from Colistin-Treated Cystic Fibrosis Patients
Moskowitz, S. M., Brannon, M. K., Dasgupta, N., Pier, M., Sgambati, N., Miller, A. K., Selgrade, S. E., Miller, S. I., Denton, M., Conway, S. P., Johansen, Helle Krogh & Høiby, Niels, Feb 2012, In: Antimicrobial Agents and Chemotherapy. 56, 2, p. 1019-1030 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sinus bacteriology in patients with cystic fibrosis or primary ciliary dyskinesia: A systematic review
Møller, M. E., Alanin, M. C., Grønhøj, C., Aanæs, Kasper, Høiby, Niels & von Buchwald, Christian, 2017, In: American Journal of Rhinology and Allergy. 31, 5, p. 293-298 6 p.Research output: Contribution to journal › Review › Research › peer-review
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Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients
Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New technology markedly improves hand-hygiene performance among healthcare workers after restroom visits
Møller-Sørensen, H., Korshin, A., Mogensen, T. & Høiby, Niels, Apr 2016, In: Journal of Hospital Infection. 92, 4, p. 337-339 3 p.Research output: Contribution to journal › Letter › Research › peer-review
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Susceptibility of Legionella species to five antibiotics and development of resistance by exposure to erythromycin, ciproflocxacin, and rifampicin
Nielsen, K., Bangsborg, Jette Marie & Høiby, Niels, 2000, In: Diagnostic Microbiology and Infectious Disease. 36, p. 43-48Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequencing of the rpoB gene in Legionella pneumophila and characterization of mutations associated with rifampicin resistance in the Legionellaceae
Nielsen, K., Hindersson, P., Høiby, Niels & Bangsborg, Jette Marie, 2000, In: Antimicrobial Agents and Chemotherapy. 44, p. 2679-2683Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dlt genes play a role in antimicrobial tolerance of Streptococcus mutans biofilms
Nilsson, Carl Martin Peter, Rybtke, Morten Levin, Givskov, Michael, Høiby, Niels, Twetman, Svante & Tolker-Nielsen, Tim, Sep 2016, In: International Journal of Antimicrobial Agents. 48, 3, p. 298–304Research output: Contribution to journal › Journal article › Research › peer-review
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A mariner transposon vector adapted for mutagenesis in oral streptococci
Nilsson, M., Christiansen, N., Høiby, Niels, Twetman, Svante, Givskov, Michael & Tolker-Nielsen, Tim, Jun 2014, In: MicrobiologyOpen. 3, 3, p. 333-40 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome sequence of Pseudomonas aeruginosa strain DK1-NH57388A, a stable mucoid cystic fibrosis isolate
Norman, A., Ciofu, Oana, Amador, C. I., Høiby, Niels & Jelsbak, L., 2016, In: Genome Announcements. 4, 1, e00008-16.Research output: Contribution to journal › Journal article › Research
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Unusual distribution of Burkholderia cepacia complex species in Danish cystic fibrosis clinics may stem from restricted transmission between patients
Nørskov-Lauritsen, N., Johansen, Helle Krogh, Fenger, M. G., Nielsen, X. C., Pressler, T., Olesen, H. V. & Høiby, Niels, 1 Aug 2010, In: Journal of Clinical Microbiology. 48, 8, p. 2981-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prehospital diagnostic and therapeutic management of otogenic Streptococcus pneumoniae meningitis
Ostergaard, C., Høiby, Niels, Konradsen, H. B. & Samuelsson, S., 2006, In: Scandinavian Journal of Infectious Diseases. 38, 3, p. 172-180 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alginate in infection
Pedersen, S. S., Høiby, Niels, Espersen, F. & Kharazmi, A., 1991, In: Antibiotics and Chemotherapy. 44, p. 68-79 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Diagnostik ved infektionssygdomme. Nocardiosis
Permin, H. & Høiby, Niels, 2002, In: Ugeskrift for læger. 164, p. 883Research output: Contribution to journal › Journal article › Research › peer-review
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Diagnostik ved infektionssygdomme
Permin, H. & Høiby, Niels, 2001, In: Ugeskrift for læger. 163, p. 2657-2658Research output: Contribution to journal › Journal article › Research › peer-review
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Diagnostik ved infektionssygdomme. Meningitis
Permin, H., Moser, C. & Høiby, Niels, 2001, In: Ugeskrift for læger. 163, p. 4174-4175Research output: Contribution to journal › Journal article › Research › peer-review
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Diagnostik ved infektionssygdomme. Pneumoni
Permin, H., Johansen, Helle Krogh & Høiby, Niels, 2001, In: Ugeskrift for læger. 163, p. 6259-6260Research output: Contribution to journal › Journal article › Research › peer-review
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Diagnostik ved infektionssygdomme. Hjerneabsces
Permin, H. & Høiby, Niels, 2002, In: Ugeskrift for læger. 164, p. 749-750Research output: Contribution to journal › Journal article › Research › peer-review
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Diagnostik ved infektionssygdomme. Actinomycosis
Permin, H. & Høiby, Niels, 2002, In: Ugeskrift for læger. 164, p. 1195-1196Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative analysis of the IgG and IgG subclass immune responses to chromosomal Pseudomonas aeruginosa beta-lactamase in serum from patients with cystic fibrosis by western blotting and laser scanning densitometry.
Petersen, T. D., Ciofu, Oana, Pressler, T., Giwercman, B., Pedersen, S. S. & Høiby, Niels, 1996, In: Thorax. 51, 7, p. 733-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Photoactivated Titanium Dioxide Nanopowders and Coating on Planktonic and Biofilm Growth of Pseudomonas aeruginosa
Polo, A., Diamanti, M. V., Bjarnsholt, Thomas, Høiby, Niels, Villa, F., Pedeferri, M. P. & Cappitelli, F., 25 Jul 2011, In: Photochemistry and Photobiology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic Pseudomonas aeruginosa infection definition: EuroCareCF Working Group report
Pressler, T., Bohmova, C., Conway, S., Dumcius, S., Hjelte, L., Høiby, Niels, Kollberg, H., Tümmler, B. & Vavrova, V., 1 Jun 2011, In: Journal of Cystic Fibrosis. 10 Suppl 2, p. S75-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnostic significance of measurements of specific IgG antibodies to Pseudomonas aeruginosa by three different serological methods
Pressler, T., Karpati, F., Granstrom, M., Knudsen, P. K., Lindblad, A., Hjelte, L., Olesen, H. V., Meyer, P. & Høiby, Niels, 2008, In: Journal of Cystic Fibrosis. 8, 1, p. 37-42 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early rise of anti-pseudomonas antibodies and a mucoid phenotype of pseudomonas aeruginosa are risk factors for development of chronic lung infection--a case control study
Pressler, T., Frederiksen, B., Skov, M., Garred, P., Koch, C. & Høiby, Niels, 2006, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 5, 1, p. 9-15 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early rise of anti-Pseudomonas antibodies and a mucoid phenotype of Pseudomonas aeruginosa are risk factors for development of chronic lung infection - A case control study (vol 5, pg 9, 2006)
Pressler, T., Frederiksen, B., Skov, M., Garred, Peter, Koch, C. & Høiby, Niels, 2007, In: Journal of Cystic Fibrosis. 6, 1, p. 79-79Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IMPACT OF EARLY AGGRESSIVE ANTIBIOTIC ERADICATION THERAPY FOR RESPIRATORY
Pressler, T., Nielsen, K. G. & Høiby, Niels, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Evaluating the "Leeds criteria'' for Pseudomonas aeruginosa infection in a cystic fibrosis centre
Proesmans, M., Balinska-Miskiewicz, W., Dupont, L., Bossuyt, X., Verhaegen, J., Høiby, Niels & Boeck, K. D., 2006, In: European Respiratory Journal. 27, 5, p. 937-943 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chronic pulmonary disease with Mycobacterium abscessus complex is a biofilm infection
Qvist, T., Eickhardt-Dalbøge, S. R., Kragh, K. N., Andersen, C. B., Iversen, M., Høiby, Niels & Bjarnsholt, Thomas, Dec 2015, In: European Respiratory Journal. 46, 6, p. 1823-1826 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Shifting paradigms of nontuberculous mycobacteria in cystic fibrosis
Qvist, T., Pressler, T., Høiby, Niels & Katzenstein, T. L., 2014, In: Respiratory research. 15, p. 1-6 6 p., 41.Research output: Contribution to journal › Comment/debate › Research
- Published
Urine lipoarabinomannan point-of-care testing in patients affected by pulmonary nontuberculous mycobacteria - experiences from the Danish Cystic Fibrosis cohort study
Qvist, T., Johansen, I. S., Pressler, T., Høiby, Niels, Andersen, A. B., Katzenstein, T. L. & Bjerrum, S., 4 Dec 2014, In: BMC Infectious Diseases. 14, p. 1-8 8 p., 655.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of a bovine antibody test for diagnosing Mycobacterium avium complex in patients with cystic fibrosis
Qvist, T., Pressler, T., Katzenstein, T. L., Høiby, Niels & Collins, M. T., Jan 2017, In: Pediatric Pulmonology. 52, 1, p. 34-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietzia papillomatosis Bacteremia
Rammer, P., Calum, Henrik Pierre, Moser, Claus Ernst, Björnsdóttir, M. K., Smedegaard, H., Høiby, Niels & Bjarnsholt, Thomas, Jun 2013, In: Journal of Clinical Microbiology. 51, 6, p. 1977-8 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Terminal truncations in Amp C beta-lactamase from a clinical isolate of Pseudomonas aeruginosa
Rasmussen, J. W., Johnsen, A. H. & Høiby, Niels, 1999, In: European Journal of Biochemistry. 263, p. 478-485Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hydrophobic character of surface regions and total hydrophobicity of four variants of chromosomal class C beta-lactamase from Pseudomonas aeruginosa are identical. Chromatographic comparison of the hydrophobic character of the variants and the effect of focusing buffer composition on the separation of the variants by chromatofocusing with internal and external pH gradients
Rasmussen, J. W. & Høiby, Niels, 2000, In: Journal of Chromatography - B. 746, p. 161-172Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SARS-CoV-2 infection dynamics in Denmark, February through October 2020: Nature of the past epidemic and how it may develop in the future
Rasmussen, S., Petersen, M. S. & Høiby, Niels, 2021, In: PLoS ONE. 16, 4 April, e0249733.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identity and effects of quorum-sensing inhibitors produced by Penicillium species
Rasmussen, T. B., Skindersoe, M. E., Bjarnsholt, T., Phipps, R. K., Christensen, K. B., Jensen, Peter Østrup, Andersen, Jens Bo, Koch, B., Larsen, T. O., Hentzer, M., Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: Microbiology. 151, Pt 5, p. 1325-40 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8427
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
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