Niels Høiby
Professor, No job title
Bacteriology
Blegdamsvej 3B, 2200 København N, 24 Bygning 24, Building: 24-1-16
Member of:
- 2012
- Published
Colonisation and infection of the paranasal sinuses in cystic fibrosis patients is accompanied by a reduced PMN response
Johansen, Helle Krogh, Aanæs, Kasper, Pressler, T., Nielsen, Kim G., Fisker, J., Skov, M., Høiby, Niels & von Buchwald, Christian, Dec 2012, In: Journal of Cystic Fibrosis. 11, 6, p. 525-531 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of lung infection in patients with cystic fibrosis: current and future strategies
Döring, G., Flume, P., Heijerman, H., Elborn, J. S. & Consensus Study Group, C. S. G., Dec 2012, In: Journal of Cystic Fibrosis. 11, 6, p. 461-479 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular epidemiology of chronic Pseudomonas aeruginosa airway infections in cystic fibrosis
Cramer, N., Wiehlmann, L., Ciofu, Oana, Tamm, S., Høiby, Niels & Tümmler, B., Nov 2012, In: PLOS ONE. 7, 11, e50731.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo
van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Qvortrup, Klaus, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Aug 2012, In: Infection and Immunity. 80, 8, p. 2601-2607 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa
Marvig, R. L., Søndergaard, M. S. R., Damkiær, S., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., Aug 2012, In: Antimicrobial Agents and Chemotherapy. 56, 8, p. 4519-4521 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combination of microscopic techniques reveals a comprehensive visual impression of biofilm structure and composition
Alhede, M., Qvortrup, Klaus, Liebrechts, R., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 335-342 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phenotypes selected during chronic lung infection in cystic fibrosis patients: implications for the treatment of Pseudomonas aeruginosa biofilm infections
Ciofu, Oana, Mandsberg, L. F., Wang, H. & Høiby, Niels, Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 215-225 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polysaccharides serve as scaffold of biofilms formed by mucoid Pseudomonas aeruginosa
Yang, L., Hengzhuang, W., Wu, H., Damkiaer, S., Jochumsen, N., Song, Z., Givskov, Michael, Høiby, Niels & Molin, S., Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 366-376 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards diagnostic guidelines for biofilm-associated infections
Hall-Stoodley, L., Stoodley, P., Kathju, S., Høiby, Niels, Moser, Claus Ernst, William Costerton, J., Moter, A. & Bjarnsholt, Thomas, Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 127-145 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Understanding biofilms - Are we there yet?
Bjarnsholt, Thomas, Høiby, Niels, Donelli, G., Imbert, C. & Försberg, A., Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 125-126 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Process for the manufacture of ajoene derivatives
Bjarnsholt, Thomas, Høiby, Niels, Jensen, Peter Østrup, Phipps, R., Shanmugham, Meenakshi, S., Alhede, M., Hultqvist, Louise Dahl, Jakobsen, Tim Holm, Tanner, D., Larsen, Thomas, O. & Givskov, Michael, 14 Jun 2012, IPC No. C07C 323/ 65 A I, Patent No. WO2012076016, Priority date 8 Dec 2010, Priority No. EP20100194154Research output: Patent
- Published
A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production
Sautter, R., Ramos, D., Schneper, L., Ciofu, Oana, Wassermann, T., Koh, C., Heydorn, A., Hentzer, M., Høiby, Niels, Kharazmi, A., Molin, S., Devries, C. A., Ohman, D. E. & Mathee, K., 1 May 2012, In: Gene. 498, 2, p. 242-253 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing
Jakobsen, Tim Holm, van Gennip, M., Phipps, R. K., Shanmugham, M. S., Hultqvist, Louise Dahl, Alhede, M., Skindersoe, M. E., Rasmussen, T. B., Friedrich, K., Uthe, F., Jensen, Peter Østrup, Moser, Claus Ernst, Nielsen, Kristian Fog, Eberl, L., Larsen, T. O., Tanner, D. A., Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., May 2012, In: Antimicrobial Agents and Chemotherapy. 56, 5, p. 2314-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo pharmacokinetics/pharmacodynamics of colistin and imipenem in Pseudomonas aeruginosa biofilm infection
Hengzhuang, W., Wu, H., Ciofu, Oana, Song, Z. & Høiby, Niels, May 2012, In: Antimicrobial Agents and Chemotherapy. 56, 5, p. 2683-2690 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model
Christensen, L., van Gennip, M., Jakobsen, Tim Holm, Alhede, M., Hougen, H. P., Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., May 2012, In: The Journal of antimicrobial chemotherapy. 67, 5, p. 1198-206 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PmrB Mutations Promote Polymyxin Resistance of Pseudomonas aeruginosa Isolated from Colistin-Treated Cystic Fibrosis Patients
Moskowitz, S. M., Brannon, M. K., Dasgupta, N., Pier, M., Sgambati, N., Miller, A. K., Selgrade, S. E., Miller, S. I., Denton, M., Conway, S. P., Johansen, Helle Krogh & Høiby, Niels, Feb 2012, In: Antimicrobial Agents and Chemotherapy. 56, 2, p. 1019-1030 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bead-size directed distribution of Pseudomonas aeruginosa results in distinct inflammatory response in a mouse model of chronic lung infection
Christophersen, L. J., Trøstrup, H., Damlund, D. S. M., Bjarnsholt, Thomas, Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, 2012, In: Experimental and clinical endocrinology. 170, 2, p. 222-30 10 p., 170.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combating biofilms
Yang, L., Liu, Y., Wu, H., Song, Z., Høiby, Niels, Molin, S. & Givskov, Michael, 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 146–157Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Culture-dependent and -independent investigations of microbial diversity on urinary catheters
Xu, Y., Moser, Claus Ernst, Abu Al-Soud, W., Sørensen, Søren Johannes, Høiby, Niels, Nielsen, P. H. & Thomsen, T. R., 2012, In: Journal of Clinical Microbiology. 50, 12, p. 3901-3908 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection
Hansen, S. K., Rau, M. H., Johansen, Helle Krogh, Ciofu, Oana, Jelsbak, L., Yang, L., Folkesson, A., Jarmer, H. Ø., Aanæs, Kasper, von Buchwald, Christian, Høiby, Niels & Molin, S., 2012, In: I S M E Journal. 6, 1, p. 31-45Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extensive endoscopic image-guided sinus surgery decreases BPI-ANCA in patients with cystic fibrosis
Aanæs, Kasper, Rasmussen, N., Pressler, T., Segelmark, M., Johansen, Helle Krogh, Lindberg, U., Høiby, Niels, Carlsson, M., Wieslander, J. & Buchwald, C., 2012, In: Scandinavian Journal of Immunology. 76, 6, p. 573-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa
Jakobsen, Tim Holm, Bragason, S. K., Phipps, R. K., Hultqvist, Louise Dahl, van Gennip, M., Alhede, M., Skindersoe, M., Larsen, T. O., Høiby, Niels, Bjarnsholt, Thomas & Givskov, Michael, 2012, In: Applied and Environmental Microbiology. 78, 7, p. 2410-2421 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathology and biofilm formation in a porcine model of staphylococcal osteomyelitis
Johansen, L. K., Koch, J., Frees, Dorte, Aalbæk, Bent, Nielsen, O. L., Leifsson, Páll S., Iburg, T. M., Svalastoga, Eiliv Lars, Buelund, Lene Elisabeth, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Henrik Elvang, 2012, In: Journal of Comparative Pathology. 147, 2-3, p. 343-353 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in Guinea Pigs
Jensen, Peter Østrup, Lykkesfeldt, Jens, Bjarnsholt, Thomas, Hougen, H. P., Høiby, Niels & Ciofu, Oana, 2012, In: Basic & Clinical Pharmacology & Toxicology. 110, 4, p. 353-358 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization
Aanæs, Kasper, Johansen, Helle Krogh, Poulsen, Steen Seier, Pressler, T., Buchwald, C. & Høiby, Niels, 2012, In: Journal of Cystic Fibrosis. 12, 1, p. 81-87 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorom sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model.
Hultqvist, Louise Dahl, van Gennip, M., Jakobsen, Tim Holm, Alhede, M., Hougen, H. P., Høiby, Niels, Bjarnsholt, Thomas & Givskov, Michael, 2012, In: Journal of Antimicrobial Chemotherapy. 67, 5, p. 1198-1206 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients
Miller, A. K., Brannon, M. K., Stevens, L., Johansen, Helle Krogh, Selgrade, S. E., Miller, S. I., Høiby, Niels & Moskowitz, S. M., 3 Oct 2011, In: Antimicrobial Agents and Chemotherapy. 55, 12, p. 5761-5769Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic pulmonary infection with Stenotrophomonas maltophilia and lung function in patients with cystic fibrosis
Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 1 Sep 2011, In: Journal of Cystic Fibrosis. 10, 5, p. 318-25 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacokinetics/Pharmacodynamics of Colistin and Imipenem on Mucoid and Nonmucoid Pseudomonas aeruginosa Biofilms
Hengzhuang, W., Wu, H., Ciofu, Oana, Song, Z. & Høiby, Niels, 1 Sep 2011, In: Antimicrobial Agents and Chemotherapy. 55, 9, p. 4469-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacokinetics/pharmacodynamics of colistin and imipenem on mucoid and nonmucoid Pseudomonas aeruginosa biofilms
Hengzhuang, W., Wu, H., Ciofu, Oana, Song, Z., Høiby, Niels & Wang, H., Sep 2011, In: Antimicrobial Agents and Chemotherapy. 55, 9, p. 4469-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of microbial diversity in endocarditis using cultivation-independent molecular techniques
Wolff, T. Y., Moser, Claus Ernst, Bundgaard, H., Høiby, Niels, Nielsen, P. H. & Thomsen, T. R., 26 Aug 2011, In: Scandinavian Journal of Infectious Diseases. 43, 11-12, p. 857-869Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pattern differentiation in co-culture biofilms formed by Staphylococcus aureus and Pseudomonas aeruginosa
Yang, L., Liu, Y., Markussen, T., Høiby, Niels, Tolker-Nielsen, Tim & Molin, S., 1 Aug 2011, In: F E M S Immunology and Medical Microbiology. 62, 3, p. 339-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Photoactivated Titanium Dioxide Nanopowders and Coating on Planktonic and Biofilm Growth of Pseudomonas aeruginosa
Polo, A., Diamanti, M. V., Bjarnsholt, Thomas, Høiby, Niels, Villa, F., Pedeferri, M. P. & Cappitelli, F., 25 Jul 2011, In: Photochemistry and Photobiology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The microorganisms in chronically infected end-stage and non-end-stage cystic fibrosis patients
Rudkjøbing, V. B., Thomsen, T. R., Alhede, M., Kragh, K. N., Nielsen, P. H., Johansen, U. R., Givskov, Michael, Høiby, Niels & Bjarnsholt, Thomas, Jul 2011, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 236-244 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic Pseudomonas aeruginosa infection definition: EuroCareCF Working Group report
Pressler, T., Bohmova, C., Conway, S., Dumcius, S., Hjelte, L., Høiby, Niels, Kollberg, H., Tümmler, B. & Vavrova, V., 1 Jun 2011, In: Journal of Cystic Fibrosis. 10 Suppl 2, p. S75-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of ginseng on Pseudomonas aeruginosa motility and biofilm formation
Wu, H., Lee, B., Yang, L., Wang, H., Givskov, Michael, Molin, S., Høiby, Niels & Song, Z., 1 Jun 2011, In: F E M S Immunology and Medical Microbiology. 62, 1, p. 49-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary dynamics of bacteria in a human host environment
Yang, L., Jelsbak, L., Marvig, R. L., Damkiær, S., Workman, C., Rau, M. H., Hansen, S. K., Folkesson, A., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels, Sommer, M. & Molin, S., 3 May 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 18, p. 7481-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Current understanding of multi-species biofilms
Yang, L., Liu, Y., Wu, H., Høiby, Niels, Molin, S. & Song, Z., 1 Apr 2011, In: International Journal of Oral Science. 3, 2, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data
Yang, L., Rau, M. H., Yang, L., Høiby, Niels, Molin, S. & Jelsbak, L., 1 Jan 2011, In: B M C Microbiology. 11, p. 184Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis
Høiby, Niels, 1 Jan 2011, In: B M C Medicine. 9, p. 32Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients
Høiby, Niels, Johansen, Helle Krogh, Moser, Claus Ernst, Ciofu, Oana, Jensen, Peter Østrup, Kolpen, Mette, Mandsberg, L., Givskov, Michael, Molin, S. & Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer, p. 167-184 18 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Anaerobic bacteria in biofilm –and their tolerance to antibiotics
Kragh, K. N., Kühl, Michael, Gregersen, A., Tvede, M., Høiby, Niels & Bjarnsholt, Thomas, 2011.Research output: Contribution to conference › Poster › Research
- Published
- Published
Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis
Aanæs, Kasper, Rickelt, L. F., Johansen, Helle Krogh, von Buchwald, Christian, Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2011, In: Journal of Cystic Fibrosis. 10, 2, p. 114-120 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of antibiotic resistance and up-regulation of the antimutator gene pfpI in mutator Pseudomonas aeruginosa due to inactivation of two DNA oxidative repair genes (mutY, mutM)
Mandsberg, L. F., Maciá, M. D., Bergmann, K. R., Christiansen, L., Alhede, M., Kirkby, N., Høiby, Niels, Oliver, A. & Ciofu, Oana, 2011, In: F E M S Microbiology Letters. 324, 1, p. 28-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hvad er stafylokokker?
Høiby, Niels, 2011Research output: Other contribution › Net publication - Internet publication › Research
- Published
Methods to classify bacterial pathogens in cystic fibrosis
Bjarnsholt, Thomas, Nielsen, X. C., Johansen, U., Nørgaard, L. & Høiby, Niels, 2011, In: Methods in Molecular Biology. 742, p. 143-71 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mucoid Pseudomonas aeruginosa isolates maintain the biofilm formation capacity and the gene expression profiles during the chronic lung infection of CF patients
Lee, B., Schjerling, C. K., Kirkby, N., Hoffmann, N., Borup, R., Molin, S., Høiby, Niels & Ciofu, Oana, 2011, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 119, 4-5, p. 263-74 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm
Alhede, M., Kragh, K. N., Qvortrup, Klaus, Allesen-Holm, M., van Gennip, M., Hultqvist, Louise Dahl, Jensen, Peter Østrup, Nielsen, A. K., Parsek, M., Wozniak, D., Molin, S., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2011, In: P L o S One. 6, 11, p. e27943Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevention of biofilm formation in the soft tissue filler Aquamid
Er, Ö., Kühl, Michael, Tvede, M., Høiby, Niels, Nielsen, A. K. & Bjarnsholt, Thomas, 2011.Research output: Contribution to conference › Poster › Research › peer-review
ID: 8427
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2962
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
Research output: Contribution to journal › Journal article › Research › peer-review
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2836
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
Research output: Contribution to journal › Journal article › Research › peer-review
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1909
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
Research output: Contribution to journal › Journal article › Research › peer-review
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