Niels Høiby

Niels Høiby

Professor, No job title

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    ORCID: 0000-0002-1347-725X

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    1. Published

      Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes

      Jakobsen, T. H., Hansen, M. A., Jensen, P. Ø., Hansen, L., Riber, L., Cockburn, A. P. I., Kolpen, M., Hansen, C. R., Ridderberg, W., Eickhardt-Sørensen, S. R., Hansen, M., Kerpedjiev, P., Alhede, M., Qvortrup, K., Burmølle, M., Moser, C. E., Kühl, M., Ciofu, O., Givskov, M., Sørensen, S. J. & 2 others, Høiby, Niels & Bjarnsholt, Thomas, 2013, In: P L o S One. 8, 7, 17 p., e68484.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors

      Jakobsen, Tim Holm, Bjarnsholt, Thomas, Jensen, Peter Østrup, Givskov, Michael & Høiby, Niels, Jul 2013, In: Future Microbiology. 8, 7, p. 901-21 21 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa

      Jakobsen, Tim Holm, Bragason, S. K., Phipps, R. K., Hultqvist, Louise Dahl, van Gennip, M., Alhede, M., Skindersoe, M., Larsen, T. O., Høiby, Niels, Bjarnsholt, Thomas & Givskov, Michael, 2012, In: Applied and Environmental Microbiology. 78, 7, p. 2410-2421 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.

      Jalal, S., Ciofu, Oana, Høiby, Niels, Gotoh, N. & Wretlind, B., 2000, In: Antimicrobial Agents and Chemotherapy. 44, 3, p. 710-2 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients.

      Jelsbak, L., Johansen, Helle Krogh, Frost, A., Thøgersen, R., Thomsen, Line Elnif, Ciofu, Oana, Yang, L., Haagensen, J. A. J., Høiby, Niels & Molin, S., 2007, In: Infection and Immunity. 75, 5, p. 2214-24 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Complement activation by Pseudomonas aeruginosa biofilms

      Jensen, E. T., Kharazmi, A., Garred, Peter, Kronborg, Gitte, Fomsgaard, A., Mollnes, T. E. & Høiby, Niels, 1993, In: Microbial Pathogenesis. 15, 5, p. 377-88 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Some bacterial parameters influencing the neutrophil oxidative burst response to Pseudomonas aeruginosa biofilms

      Jensen, E. T., Kharazmi, A., Høiby, Niels & Costerton, J. W., 1992, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 100, 8, p. 727-33 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Epidemiology of Pseudomonas aeruginosa in cystic fibrosis and the possible role of contamination by dental equipment

      Jensen, E. T., Giwercman, B., Ojeniyi, B., Bangsborg, Jette Marie, Hansen, A., Koch, C., Fiehn, Nils-Erik & Høiby, Niels, 1997, In: Journal of Hospital Infection. 36, 2, p. 117-22 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Epidemiology of Pseudomonas aeruginosa in cystic frbrosis patients and the possible role of contamination by dental equipment

      Jensen, E. T., Giwercman, B., Ojeniyi, B., Bangsborg, J. M., Hansen, A., Kock, C., Fiehn, Nils-Erik & Høiby, Niels, 1997, In: Journal of Hospital Infection. 36, p. 117-122

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Autoantibodies to pancreatic hsp60 precede the development of glucose intolerance in patients with cystic fibrosis

      Jensen, P., Johansen, Helle Krogh, Carmi, P., Høiby, Niels & Cohen, I. R., 2001, In: J. Autoimmunity. 17, p. 165-172

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air

      Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-Jepsen, Daniel, Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in Guinea Pigs

      Jensen, Peter Østrup, Lykkesfeldt, Jens, Bjarnsholt, Thomas, Hougen, H. P., Høiby, Niels & Ciofu, Oana, 2012, In: Basic & Clinical Pharmacology & Toxicology. 110, 4, p. 353-358 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Nitric oxide production by polymorphonuclear leukocytes in sputum from CF patients with chronic lung infection

      Jensen, Peter Østrup, Kolpen, M., Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Pressler, T. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    14. Published

      Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa

      Jensen, Peter Østrup, Bjarnsholt, Thomas, Phipps, R., Rasmussen, T. B., Calum, H., Christoffersen, L., Moser, C., Williams, P., Pressler, T., Givskov, Michael & Høiby, Niels, 2007, In: Microbiology. 153, Pt 5, p. 1329-38 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms

      Jensen, Peter Østrup, Briales, A., Brochmann, R. P., Wang, H., Kragh, K. N., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Ciofu, Oana, 2014, In: Pathogens and Disease. 70, 3, p. 440-443 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Hyperbaric Oxygen Treatment May Advance the Outcome of Antibiotic Treatment of Biofilm Infections

      Jensen, Peter Østrup, Møller, S. A., Stjernekilde, S., Olsen, P., Moser, Claus Ernst, Schwartz, F. A., Lerche, C. J., Høiby, Niels, Hyldegaard, Ole, Faurholt-jepsen, D. & Kolpen, Mette, 2022, Antibiofilm Strategies: Current and Future Applications to Prevent, Control and Eradicate Biofilms. Springer, p. 201-223 (Antibiofilm Strategies, Vol. 11).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    17. Published

      Faster activation of polymorphonuclear neutrophils in resistant mice during early innate response to Pseudomonas aeruginosa lung infection

      Jensen, Peter Østrup, Moser, Claus Ernst, Kobayashi, O., Hougen, H. P., Kharazmi, A. & Høiby, Niels, 2004, In: Clinical and Experimental Immunology. 137, 3, p. 478-485 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Increased serum concentration of G-CSF in cystic fibrosis patients with chronic Pseudomonas aeruginosa pneumonia

      Jensen, Peter Østrup, Moser, Claus Ernst, Kharazmi, A., Presler, T., Koch, C. & Høiby, Niels, Aug 2006, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 5, 3, p. 145-51 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia in rats

      Johansen, Helle Krogh, Hougen, H. P., Cryz, S. J., Rygaard, J. & Høiby, Niels, 1995, In: American Journal of Respiratory and Critical Care Medicine. 152, 4 Pt 1, p. 1337-46 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Chronic Pseudomonas aeruginosa lung infection in normal and athymic rats

      Johansen, Helle Krogh, Espersen, F., Pedersen, S. S., Hougen, H. P., Rygaard, J. & Høiby, Niels, 1993, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 101, 3, p. 207-225 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Immunization with Pseudomonas aeruginosa vaccines and adjuvant can modulate the type of inflammatory response subsequent to infection

      Johansen, Helle Krogh, Espersen, F., Cryz, S. J., Hougen, H. P., Fomsgaard, A., Rygaard, J. & Høiby, Niels, 1994, In: Infection and Immunity. 62, 8, p. 3146-55 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Interferon-gamma (IFN-gamma) treatment decreases the inflammatory response in chronic Pseudomonas aeruginosa pneumonia in rats

      Johansen, Helle Krogh, Hougen, H. P., Rygaard, J. & Høiby, Niels, 1996, In: Clinical and Experimental Immunology. 103, 2, p. 212-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia. A new prophylactic principle

      Johansen, Helle Krogh, Cryz, S. J., Hougen, H. P., Moser, Claus Ernst & Høiby, Niels, 1997, In: Behring Institute Mitteilungen. 98, p. 269-73 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      [Has the new technology made Gram's staining method redundant? The Danish Society of Clinical Microbiology]

      Johansen, H. K., Bjarnsholt, T. & Høiby, Niels, 2008, In: Ugeskrift for læger. 170, 12, p. 1041-

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Klinisk bakteriologi, infektionshygiejne og antibiotikabehandling

      Johansen, H. K., Andersen, L. P., Skinhoj, P., Høiby, Niels & Johansen, Helle Krogh, 2008, Klinisk Mikrobiologi og Infektionsmedicin. 3rd ed. København: FADL's Forlag, Vol. 6. p. 223-298 75 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    26. Published

      Antibody response to Pseudomonas aeruginosa in cystic fibrosis patients: a marker of therapeutic success? - A 30-year cohort study of survival in Danish CF patients after onset of chronic P. aeruginosa lung infection

      Johansen, Helle Krogh, Nørregaard, L., Gøtzsche, P. C., Pressler, T., Koch, C. & Høiby, Niels, 2004, In: Pediatric Pulmonology. 37, 5, p. 427-432

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Randomised trial of pivampicillin plus pivmecillinam vs. pivampicillin in children and young adults with chronic obstructive pulmonary disease and infection with Haemophilus influenzae

      Johansen, Helle Krogh, Børch, K., Espersen, F., Koch, C. & Høiby, Niels, 1999, In: Current Medical Research and Opinion. 15(4), p. 300-309

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Gene transcription profiles of paired mucoid & non-mucoid P. aeruginosa isolates from sinuses and lungs of patients with cystic fibrosis

      Johansen, Helle Krogh, Wassermann, T., Alhede, M., Aanæs, Kasper, Buchwald, C. V. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    29. Published

      Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients.

      Johansen, Helle Krogh, Moskowitz, S. M., Ciofu, Oana, Pressler, T. & Høiby, Niels, 2008, In: Journal of Cystic Fibrosis. 7, 5, p. 391-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Pseudomonas mendocina as a cause of chronic infective endocarditis in a patient with situs inversus

      Johansen, Helle Krogh, Kjeldsen, K. & Høiby, Niels, 2001, In: Clinical Microbiology and Infection. 7, p. 650-652

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Colonisation and infection of the paranasal sinuses in cystic fibrosis patients is accompanied by a reduced PMN response

      Johansen, Helle Krogh, Aanæs, Kasper, Pressler, T., Nielsen, Kim G., Fisker, J., Skov, M., Høiby, Niels & von Buchwald, Christian, Dec 2012, In: Journal of Cystic Fibrosis. 11, 6, p. 525-531 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Har ny teknologi overflødiggjort Grams farvemetode? Dansk Selskab for Klinisk Mikrobiologi

      Johansen, Helle Krogh, Bjarnsholt, Thomas, Høiby, Niels & Dansk Selskab for Klinisk Mikrobiologi, D. S. F. K. M., 17 Mar 2008, In: Ugeskrift for læger. 170, 12, p. 1041

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Rat model of chronic Pseudomonas aeruginosa lung infection

      Johansen, Helle Krogh & Høiby, Niels, 1999, Handbook of animal models of infection. Academic Press, p. 517-526

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

    34. Published

      Pathology and biofilm formation in a porcine model of staphylococcal osteomyelitis

      Johansen, L. K., Koch, J., Frees, Dorte, Aalbæk, Bent, Nielsen, O. L., Leifsson, Páll S., Iburg, T. M., Svalastoga, Eiliv Lars, Buelund, Lene Elisabeth, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Henrik Elvang, 2012, In: Journal of Comparative Pathology. 147, 2-3, p. 343-353 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Epidemic spread of Pandoraea apista, a new pathogen causing severe lung disease in cystic fibrosis patients

      Jorgensen, I. M., Johansen, Helle Krogh, Frederiksen, B., Pressler, T., Hansen, A., Vandamme, P., Høiby, Niels & Koch, C., 2003, In: Pediatric Pulmonology. 36(5), p. 439-446

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection

      Jorgensen, K. M., Wassermann, T., Johansen, Helle Krogh, Christiansen, L. E., Molin, S., Høiby, Niels & Ciofu, Oana, Jul 2015, In: Microbiology. 161, 7, p. 1447-1462 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Sublethal ciprofloxacin treatment leads to rapid development of high-level ciprofloxacin resistance during long-term experimental evolution of Pseudomonas aeruginosa

      Jørgensen, K. M., Wassermann, T., Jensen, Peter Østrup, Hengzuang, W., Molin, S., Høiby, Niels & Ciofu, Oana, Sep 2013, In: Antimicrobial Agents and Chemotherapy. 57, 9, p. 4215-21 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Pseudomonas aeruginosa pyocyanin and 1-hydroxyphenazine inhibit fungal growth

      Kerr, J. R., Taylor, G. W., Rutman, A., Høiby, Niels, Cole, P. J. & Wilson, R., 1999, In: Journal of Clinical Pathology. 52, p. 385-387

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Relationship between chemical composition and biological function of Pseudomonas aeruginosa lipopolysaccharide: effect on human neutrophil chemotaxis and oxidative burst

      Kharazmi, A., Fomsgaard, A., Conrad, R. S., Galanos, C. & Høiby, Niels, 1991, In: Journal of Leukocyte Biology. 49, 1, p. 15-20 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Pseudomonas aeruginosa septicaemia in a patient with severe Plasmodium falciparum

      Kharazmi, A., Høiby, Niels & Theander, Thor Grundtvig, 1987, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 81, 1, p. 49-50 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Polymorphonuclear leukocytes and pseudomonas aeruginosa biofilm

      Kharazmi, A., Mathee, K., Jensen, E. T., Molin, S. & Høiby, Niels, 1999, In: Clinical Microbiology and Infection. 5, p. S27-S28

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Robbins device in biofilm research

      Kharazmi, A., Giwercman, B. & Høiby, Niels, 1999, Methods in enzymology, vol. 310. San Diego, USA: Academic Press, p. 207-215

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    43. Published

      Experimental Pseudomonas aeruginosa mediated rhino sinusitis in mink

      Kirkeby, Svend, Hammer, Anne Sofie Vedsted, Høiby, Niels & Salomonsen, C. M., May 2017, In: International Journal of Pediatric Otorhinolaryngology. 96, p. 156-163 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Distribution, organization, and ecology of bacteria in chronic wounds

      Kirketerp-Møller, K., Jensen, Peter Østrup, Fazli, M., Madsen, K. G., Pedersen, J., Moser, C., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Aug 2008, In: Journal of Clinical Microbiology. 46, 8, p. 2717-22 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Infektiøs endokardit

      Kjeldsen, K., Høiby, Niels, Egeblad, H., Muckadell, O. B. S. D., Haunsoe, S. & Vilstrup, H., 2009, Medicinsk Kompendium. 17th ed. København: Dansk Sygeplejeråd, p. 1047-1057 10 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    46. Published

      Mindre endokarditisprofylakse

      Kjeldsen, K., Haunsø, S. & Høiby, Niels, 22 Feb 2010, In: Ugeskrift for Laeger. 172, 8, p. 599

      Research output: Contribution to journal › Editorial › Research

    47. Published

      Serological diagnosis of experimental Enterococcus faecalis endocarditis

      Kjerulf, A., Espersen, F., Gutschik, E., Majcherczyk, P. A., Hougen, H. P., Rygaard, J. & Høiby, Niels, 1998, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 106, 10, p. 997-1008 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Listerias følsomhed for penicillin, ampicillin, piperacillin og meropenem. Hvad er den bedste behandling?

      Knudsen, J. D., Østergaard, C. & Høiby, Niels, 2002, In: Nyt om Mikrobiologi. 59, p. 6-9

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Rapid identification of Stenotrophomonas maltophilia by peptide nucleic acid fluorescence in situ hybridization

      Knudsen, N. R., Rasmussen, A. K. I., Fiandaca, M. J., Kragh, K. N., Bjarnsholt, Thomas, Høiby, Niels, Stender, H. & Guardabassi, Luca, 2014, In: New Microbes and New Infections. 2, 3, p. 79-81 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Differences in prevalence and treatment of Pseudomonas aeruginosa in cystic fibrosis centres in Denmark, Norway and Sweden

      Knudsen, P. K., Olesen, H. V., Høiby, Niels, Johannesson, M., Karpati, F., Laerum, B. N., Meyer, P., Pressler, T., Lindblad, A. & Scandinavian CF Study Consortium (SCFSC), S. C. S. C. (., 2009, In: Journal of Cystic Fibrosis. 8, 2, p. 135-42 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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