Thomas Bjarnsholt
Professor
Bacteriology
Nørre Allé 14
2200 København N
- 2014
- Published
Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
Line, L., Alhede, M., Kolpen, Mette, Kühl, Michael, Ciofu, Oana, Bjarnsholt, Thomas, Moser, Claus Ernst, Toyofuku, M., Nomura, N., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Frontiers in Microbiology. 5, 11 p., 554.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymorphonuclear leukocytes restrict growth of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients
Kragh, K. N., Alhede, M., Jensen, Peter Østrup, Moser, Claus Ernst, Scheike, Thomas, Jacobsen, C. S., Poulsen, Steen Seier, Eickhardt-Sørensen, S. R., Trostrup, H., Christoffersen, L., Hougen, H. P., Rickelt, L. F., Kühl, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2014, In: Infection and Immunity. 82, 11, p. 4477-4486 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa Biofilms: Mechanisms of Immune Evasion
Alhede, M., Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., 2014, In: Advances in Applied Microbiology. 86, p. 1-40 40 p.Research output: Contribution to journal › Journal article › Research
- Published
Rapid identification of Stenotrophomonas maltophilia by peptide nucleic acid fluorescence in situ hybridization
Knudsen, N. R., Rasmussen, A. K. I., Fiandaca, M. J., Kragh, K. N., Bjarnsholt, Thomas, Høiby, Niels, Stender, H. & Guardabassi, Luca, 2014, In: New Microbes and New Infections. 2, 3, p. 79-81 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?
Aanæs, Kasper, Eickhardt, S., Johansen, Helle Krogh, von Buchwald, Christian, Skov, M., Høiby, Niels & Bjarnsholt, Thomas, 2014, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial biofilm formation and treatment in soft tissue fillers
Alhede, M., Er, O., Eickhardt, S., Kragh, K., Alhede, M., Hultqvist, Louise Dahl, Poulsen, Steen Seier, Givskov, Michael, Christensen, L. H., Høiby, Niels, Tvede, M. & Bjarnsholt, Thomas, 30 Jan 2014, In: Pathogens and Disease. 70, p. 339-346 8 p.Research output: Contribution to journal › Journal article › Research
- Published
Microbial biofilms--the coming of age of a research field
Coenye, T., Van Dijck, P., Bjarnsholt, Thomas & Forsberg, A., Apr 2014, In: Pathogens and Disease. 70, 3, p. 203-4 2 p.Research output: Contribution to journal › Journal article › Research
- Published
Biofilms in wounds: a review of present knowledge
Cooper, R. A., Bjarnsholt, Thomas & Alhede, M., Nov 2014, In: Journal of Wound Care. 23, 11, p. 570, 572-4, 576-80 passim 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model
Cao, B., Christophersen, L., Thomsen, K., Sønderholm, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2015, In: The Journal of antimicrobial chemotherapy. 70, 7, p. 2057-2063 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Autofluorescence in samples obtained from chronic biofilm infections – “all that glitters is not gold”
Eickhardt-Dalbøge, S. R., Kragh, K. N., Schrøder, S., Poulsen, Steen Seier, Sillesen, Henrik, Givskov, Michael, Høiby, Niels, Bjarnsholt, Thomas & Alhede, M., 2015, In: Pathogens and Disease. 73, 4, 4 p., ftv012.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Denitrification by cystic fibrosis pathogens - Stenotrophomonas maltophilia is dormant in sputum
Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas, Line, L., Hansen, C. R., Dalbøge, C. S., Hansen, N., Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2015, In: International Journal of Medical Microbiology. 305, 1, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluorescence in situ hybridization for the tissue detection of bacterial pathogens associated with porcine infections.
Jensen, Henrik Elvang, Jensen, Louise Kruse, Barington, Kristiane, Pors, S. E., Bjarnsholt, Thomas & Boye, M., 2015, In: Methods in Molecular Biology. 1247, p. 219-134 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HUMAN SKIN MICROORGANISMS ARE DISTRIBUTED IN BIOFILM AGGREGATES AT WOUND EDGES
Bay, Lene, Agren, M. S., Poulsen, Steen Seier, Ghathian, K. S. A., Calum, H. & Bjarnsholt, Thomas, 2015, In: Wound Repair and Regeneration. 23, 4, p. A3-A3 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
In silico analyses of metagenomes from human atherosclerotic plaque samples
Mitra, S., Drautz-Moses, D. I., Alhede, M., Maw, M. T., Liu, Y., Purbojati, R. W., Yap, Z. H., Kushwaha, K. K., Gheorghe, Alexandra Gabriella, Bjarnsholt, Thomas, Hansen, G. M., Sillesen, Henrik, Hougen, H. P., Hansen, Peter Riis, Yang, L., Tolker-Nielsen, Tim, Schuster, S. C. & Givskov, Michael, 2015, In: Microbiome. 3, p. 1-14 38.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbial biofilms and adverse reactions to gel fillers used in cosmetic surgery
Alhede, M., Christensen, L. H. & Bjarnsholt, Thomas, 2015, In: Advances in Experimental Medicine and Biology. 831, p. 45-52 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific antibodies to Staphylococcus aureus biofilm are present in serum from pigs with osteomyelitis
Jensen, Louise Kruse, Jensen, Henrik Elvang, Koch, J., Bjarnsholt, Thomas, Eickhardt-Dalbøge, S. R. & Shirtliff, M., 2015, In: In Vivo. 29, p. 555-560 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ESCMID guideline for the diagnosis and treatment of biofilm infections 2014
Høiby, Niels, Bjarnsholt, Thomas, Moser, C., Bassi, G. L., Coenye, T., Donelli, G., Hall-Stoodley, L., Holá, V., Imbert, C., Kirketerp-Møller, K., Lebeaux, D., Oliver, A., Ullmann, A. J., Williams, C. & ESCMID Study Group for Biofilms (ESGB) and Consulting External Expert Werner Zimmerli, E. S. G. F. B. (. A. C. E. E. W. Z., 14 Jan 2015, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 21, Suppl. 1, p. s1-s25 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Density of Competitors in a Stratified Environment Determines the Relative Fitness of Biofilm Structures
Gordon, V. D., Kragh, K. N., Hutchison, J. B., Melaugh, G., Rodesney, C. A., Irie, Y., Diggle, S., Allen, R. J. & Bjarnsholt, Thomas, 9 Feb 2015, In: Biophysical Journal. 108, 2, supplement 1, p. 313A-313A 1 p., 1568-Pos.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
A novel in vitro wound biofilm model used to evaluate low-frequency ultrasonic-assisted wound debridement
Crone, S., Garde, C., Bjarnsholt, Thomas & Alhede, M., Mar 2015, In: Journal of Wound Care. 24, 2, p. 64-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mucosal biofilm detection in chronic otitis media: a study of middle ear biopsies from Greenlandic patients
Wessman, M., Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R., Johansen, Helle Krogh & Homøe, Preben, May 2015, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 272, 5, p. 1079-1085 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiofilm Properties of Acetic Acid
Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unexpected Diagnosis of Cerebral Toxoplasmosis by 16S and D2 Large-Subunit Ribosomal DNA PCR and Sequencing
Kruse, Alexandra Yasmin Collin, Kvich, Lasse Andersson, Eickhardt-Dalbøge, S. R., Omland, L. H., Bjarnsholt, Thomas & Moser, Claus Ernst, Jun 2015, In: Journal of Clinical Microbiology. 53, 6, p. 1983-1985 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils
Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Jul 2015, In: Infection and Immunity. 83, 7, p. 2686-2693 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RE-SENSITIZATION OF ANOXIC PSEUDOMONAS AERUGINOSA BIOFILMS WITH RE-OXYGENATION USING HYPERBARIC OXYGEN TREATMENT
Kolpen, Mette, Mousavi, N., Sams, T., Kragh, K. N., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, P. O., Oct 2015, In: Pediatric Pulmonology. 50, S41, p. 312-312 1 p., 322.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The Limitations of In Vitro Experimentation in Understanding Biofilms and Chronic Infection
Roberts, A. E. L., Kragh, K. N., Bjarnsholt, Thomas & Diggle, S. P., 20 Nov 2015, In: Journal of Molecular Biology. 427, 23, p. 3646-3661 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Chronic pulmonary disease with Mycobacterium abscessus complex is a biofilm infection
Qvist, T., Eickhardt-Dalbøge, S. R., Kragh, K. N., Andersen, C. B., Iversen, M., Høiby, Niels & Bjarnsholt, Thomas, Dec 2015, In: European Respiratory Journal. 46, 6, p. 1823-1826 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2016
- Published
Interspecific bacterial interactions are reflected in multispecies biofilm spatial organization
Liu, W., Røder, Henriette Lyng, Madsen, Jonas Stenløkke, Bjarnsholt, Thomas, Sørensen, Søren Johannes & Burmølle, Mette, 2016, In: Frontiers in Microbiology. 7, 8 p., 1366.Research output: Contribution to journal › Review › Research › peer-review
- Published
Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment
Kolpen, Mette, Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions
Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model
Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shaping the growth behaviour of biofilms initiated from bacterial aggregates
Melaugh, G., Hutchison, J., Kragh, K. N., Irie, Y., Roberts, A., Bjarnsholt, Thomas, Diggle, S. P., Gordon, V. D. & Allen, R. J., 2 Mar 2016, In: P L o S One. 11, 3, 18 p., e0149683.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of multicellular aggregates in biofilm formation
Kragh, K. N., Hutchison, J. B., Melaugh, G., Rodesney, C., Roberts, A. E. L., Irie, Y., Jensen, Peter Østrup, Diggle, S. P., Allen, R. J., Gordon, V. & Bjarnsholt, Thomas, 22 Mar 2016, In: mBio. 7, 2, 11 p., e00237-16.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The phenotypic evolution of pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin
Wassermann, T., Jørgensen, K. M., Ivanyshyn, K., Bjarnsholt, Thomas, Hossein Khademi, S. M., Jelsbak, L., Høiby, Niels & Ciofu, Oana, 1 May 2016, In: Microbiology. 162, 5, p. 865-875 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils
Thomsen, K., Christophersen, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, Claus Ernst & Høiby, Niels, Jul 2016, In: Human Vaccines & Immunotherapeutics. 12, 7, p. 1690-1699 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Achromobacter Species Isolated from Cystic Fibrosis Patients Reveal Distinctly Different Biofilm Morphotypes
Nielsen, S. M., Nørskov-Lauritsen, N., Bjarnsholt, Thomas & Meyer, R. L., Sep 2016, In: Microorganisms. 4, 3, 16 p., 33.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Editorial: The complexity of microbial biofilm research-an introduction to the third thematic issue on biofilms
Coenye, T. & Bjarnsholt, Thomas, Oct 2016, In: Pathogens and Disease. 74, 7, 2 p., ftw053.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Maxillary Sinus Impaction of a Core Carrier Causing Sustained Apical Periodontitis, Sinusitis, and Nasal Stenosis: A 3-year Follow-up
Bjørndal, Lars, Amaloo, C., Markvart, Merete, Rud, V., Qvortrup, Klaus, Stavnsbjerg, Camilla & Bjarnsholt, Thomas, 18 Oct 2016, In: The Journal of Endodontics. 42, 12, p. 1851-1858 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incidence of Propionibacterium acnes in initially culture-negative thioglycollate broths: a prospective cohort study at a Danish University Hospital
Kvich, Lasse Andersson, Jensen, Peter Østrup, Justesen, U. S. & Bjarnsholt, Thomas, Nov 2016, In: Clinical Microbiology and Infection. 22, 11, p. 941-945Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparing culture and molecular methods for the identification of microorganisms involved in necrotizing soft tissue infections
Rudkjøbing, V. B., Thomsen, T. R., Xu, Y., Melton-Kreft, R., Ahmed, A., Eickhardt-Dalbøge, S. R., Bjarnsholt, Thomas, Poulsen, Steen Seier, Nielsen, P. H., Earl, J. P., Ehrlich, G. D. & Moser, Claus Ernst, 8 Nov 2016, In: B M C Infectious Diseases. 16, 13 p., 652.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Bacterial biofilm in chronic lesions of Hidradenitis Suppurativa
Ring, H. C., Bay, Lene, Nilsson, Carl Martin Peter, Kallenbach, K., Miller, I. M., Saunte, Ditte Marie, Bjarnsholt, Thomas, Tolker-Nielsen, Tim & Jemec, Gregor, 2017, In: British Journal of Dermatology. 176, 4, p. 993–1000Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inactivation of Pseudomonas aeruginosa biofilm after ultraviolet light-emitting diode treatment: a comparative study between ultraviolet C and ultraviolet B
Argyraki, A., Markvart, Merete, Bjørndal, Lars, Bjarnsholt, Thomas & Petersen, P. M., 2017, In: Journal of Biomedical Optics. 22, 6, 7 p., 65004.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel porcine model of implant-associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response
Jensen, Louise Kruse, Koch, J., Dich-Jørgensen, K., Aalbæk, Bent, Petersen, A., Fuursted, K., Bjarnsholt, Thomas, Kragh, K. N., Tøtterup, M., Bue, M., Hanberg, P., Søballe, K., Heegaard, P. M. H. & Jensen, Henrik Elvang, 2017, In: Journal of Orthopaedic Research. 35, 10, p. 2211–2221Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Pseudomonas aeruginosa PSL polysaccharide is a social but noncheatable trait in biofilms
Irie, Y., Roberts, A. E. L., Kragh, K. N., Gordon, V. D., Hutchison, J., Allen, R. J., Melaugh, G., Bjarnsholt, Thomas, West, S. A. & Diggle, S. P., 2017, In: mBio. 8, 3, 13 p., e00374-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The consequences of being in an infectious biofilm – microenvironmental conditions governing antibiotic tolerance
Sønderholm, M., Bjarnsholt, Thomas, Alhede, M., Kolpen, Mette, Jensen, Peter Østrup, Kühl, Michael & Kragh, K. N., 2017, In: International Journal of Molecular Sciences. 18, 12, 14 p., 2688.Research output: Contribution to journal › Review › Research › peer-review
- Published
The follicular skin microbiome in patients with hidradenitis suppurativa and healthy controls
Ring, H. C., Thorsen, J., Saunte, Ditte Marie, Lilje, B., Bay, Lene, Riis, P. T., Larsen, N., Andersen, L. O., Nielsen, H. V., Miller, I. M., Bjarnsholt, Thomas, Fuursted, K. & Jemec, Gregor, 2017, In: JAMA Dermatology. 153, 9, p. 897-905 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early implant-associated osteomyelitis results in a peri-implanted bacterial reservoir
Jensen, Louise Kruse, Koch, J., Aalbæk, Bent, Moodley, Arshnee, Bjarnsholt, Thomas, Kragh, K. N., Petersen, A. & Jensen, Henrik Elvang, Jan 2017, In: APMIS - Journal of Pathology, Microbiology and Immunology. 125, 1, p. 38-45 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The prevalence of biofilms in chronic wounds: a systematic review and meta-analysis of published data
Malone, M., Bjarnsholt, Thomas, McBain, A. J., James, G. A., Stoodley, P., Leaper, D., Tachi, M., Schultz, G., Swanson, T. & Wolcott, R. D., Jan 2017, In: Journal of Wound Care. 26, 1, p. 20-25Research output: Contribution to journal › Review › Research › peer-review
- Published
Normal Skin Microbiota is Altered in Pre-clinical Hidradenitis Suppurativa
Ring, H. C., Bay, Lene, Kallenbach, K., Miller, I. M., Prens, E., Saunte, Ditte Marie, Bjarnsholt, Thomas & Jemec, Gregor, Feb 2017, In: Acta Dermato-Venereologica. 97, 2, p. 208-213Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phage inhibit pathogen dissemination by targeting bacterial migrants in a chronic infection model
Darch, S. E., Kragh, K. N., Abbott, E. A., Bjarnsholt, Thomas, Bull, J. J. & Whiteley, M., Mar 2017, In: mBio. 8, 2, 15 p., e00240-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of two commercial broadrange PCR and sequencing assays for identification of bacteria in culture-negative clinical samples
Stavnsbjerg, Camilla, Frimodt-Moller, N., Moser, C. E. & Bjarnsholt, Thomas, 27 Mar 2017, In: B M C Infectious Diseases. 17, 7 p., 233.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnosis of biofilm infections in cystic fibrosis patients
Høiby, Niels, Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup, Kolpen, Mette, Qvist, T., Aanæs, Kasper, Pressler, T., Skov, M. & Ciofu, Oana, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 339-343 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Pseudomonas aeruginosa aggregate formation in an alginate bead model system exhibits In Vivo-like characteristics
Sønderholm, M., Kragh, K. N., Koren, K., Jakobsen, Tim Holm, Darch, S., Alhede, M., Jensen, Peter Østrup, Whiteley, M., Kühl, Michael & Bjarnsholt, Thomas, May 2017, In: Applied and Environmental Microbiology. 83, 9, 15 p., e00113-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The occurrence of biofilm in an equine experimental wound model of healing by secondary intention
Jørgensen, Elin , Bay, Lene, Bjarnsholt, Thomas, Bundgaard, L., Sørensen, M. A. & Jacobsen, Stine, May 2017, In: Veterinary Microbiology. 204, p. 90-95 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?
Jensen, Ramon Gordon, Johansen, Helle Krogh, Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R. & Homøe, Preben, Jul 2017, In: European Archives of Oto-Rhino-Laryngology. 274, 7, p. 2741-2747 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Consensus guidelines for the identification and treatment of biofilms in chronic nonhealing wounds
Schultz, G., Bjarnsholt, Thomas, James, G. A., Leaper, D. J., McBain, A. J., Malone, M., Stoodley, P., Swanson, T., Tachi, M. & Wolcott, R. D., Sep 2017, In: Wound Repair and Regeneration. 25, 5, p. 744-757 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
O-2 AFFECTS THE ACTIVITY OF AMIKACIN ON MYCOBACTERIUM ABSCESSUS BIOFILM
Kolpen, M., Ravnholt, C., Qvist, T., Kragh, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, Sep 2017, In: Pediatric Pulmonology. 52, S47, p. S359-S360 379.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Haematoxylin and eosin staining identifies medium to large bacterial aggregates with a reliable specificity: A comparative analysis of follicular bacterial aggregates in axillary biopsies using peptide nucleic acid-fluorescence in situ hybridization and haematoxylin and eosin staining
Ring, H. C., Riis, P. T., Bay, Lene, Kallenbach, K., Bjarnsholt, Thomas & Jemec, Gregor, Oct 2017, In: Experimental Dermatology. 26, 10, p. 943-945Research output: Contribution to journal › Letter › Research › peer-review
- Published
Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin
Kolpen, Mette, Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heading for centennial anniversary and beyond
Norrild, B., Ralfkiaer, E., Bjarnsholt, Thomas & Jensen, Peter Østrup, Dec 2017, In: APMIS. 125, 12, p. 1133-1133Research output: Contribution to journal › Editorial › Research
- 2018
- Published
Bacterial biofilms: a possible mechanism for chronic infection in patients with lumbar disc herniation - a prospective proof-of-concept study using fluorescence in situ hybridization
Ohrt-Nissen, S., Fritz, Blaine Gabriel, Walbom, J., Kragh, K. N., Bjarnsholt, Thomas, Dahl, Benny & Manniche, C., 2018, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 126, 5, p. 440-447 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilm formation – what we can learn from recent developments
Bjarnsholt, Thomas, Buhlin, K., Dufrêne, Y. F., Gomelsky, M., Moroni, A., Ramstedt, M., Rumbaugh, K. P., Schulte, T., Sun, L., Åkerlund, B. & Römling, U., 2018, In: Journal of Internal Medicine. 284, 4, p. 332-345 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Combined Staining Techniques for Demonstration of Staphylococcus aureus Biofilm in Routine Histopathology
Jensen, Louise Kruse, Henriksen, Nicole Lind, Bjarnsholt, Thomas, Kragh, K. N. & Jensen, Henrik Elvang, 2018, In: Journal of Bone and Joint Infection. 3, 1, p. 27-36Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In memoriam-Mark E. Shirtliff (1969-2018)
Coenye, T., Bjarnsholt, Thomas, Stoodley, P. & Rumbaugh, K., 2018, In: Pathogens and Disease. 76, 7, fty068.Research output: Contribution to journal › Editorial › Research
- Published
Inoculation method could impact the outcome of microbiological experiments
Kragh, K. N., Alhede, M., Rybtke, Morten Levin, Stavnsbjerg, Camilla, Tolker-Nielsen, Tim, Whiteley, M. & Bjarnsholt, Thomas, 2018, In: Applied and Environmental Microbiology. 84, 5, 14 p., e02264-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin
Woetmann, Anders , Alhede, M., Dabelsteen, Sally, Bjarnsholt, Thomas, Rybtke, Morten Levin, Nastasi, C., Krejsgaard, T., Andersen, Mads Hald, Bonefeld, Charlotte Menne, Geisler, Carsten, Givskov, Michael & Ødum, Niels, 2018, In: OncoTarget. 9, 28, p. 19481-19489 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Moderate to severe hidradenitis suppurativa patients do not have an altered bacterial composition in peripheral blood compared to healthy controls
Ring, H. C., Thorsen, Jonathan Jan Ilve, Saunte, Ditte Marie, Lilje, B., Bay, Lene, Theut Riis, P., Larsen, N., O'Brien Andersen, L., Vedel Nielsen, H., Miller, I. M., Bjarnsholt, Thomas, Fuursted, K. & Jemec, Gregor, 2018, In: Journal of the European Academy of Dermatology and Venereology. 32, 1, p. 125-128 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Morphological evidence of biofilm in chronic obstructive sialadenitis
Schrøder, S. A., Eickhardt, S., Bjarnsholt, Thomas, Nørgaard, T. & Homøe, Preben, 2018, In: Journal of Laryngology and Otology. 132, 7, p. 611-614 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa transcriptome during human infection
Cornforth, D. M., Dees, J. L., Ibberson, C. B., Huse, H. K., Mathiesen, I. H., Kirketerp-Møller, K., Wolcott, R. D., Rumbaugh, K. P., Bjarnsholt, Thomas & Whiteley, M., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 22, p. E5125-E5134Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Should standardized susceptibility testing for microbial biofilms be introduced in clinical practice?
Coenye, T., Goeres, D., Van Bambeke, F. & Bjarnsholt, Thomas, 2018, In: Clinical Microbiology and Infection. 24, 6, p. 570–572 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The use of fluorescent staining techniques for microscopic investigation of polymorphonuclear leukocytes and bacteria
Alhede, M., Stavnsbjerg, Camilla & Bjarnsholt, Thomas, 2018, In: APMIS. 126, 10, p. 779-794 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model
Sønderholm, M., Koren, K., Wangpraseurt, D., Jensen, Peter Østrup, Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas & Kühl, Michael, 2018, In: npj Biofilms and Microbiomes. 4, 11 p., 3.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV light assisted antibiotics for eradication of in vitro biofilms
Argyraki, A., Markvart, Merete, Stavnsbjerg, Camilla, Kragh, K. N., Ou, Y., Bjørndal, Lars, Bjarnsholt, Thomas & Petersen, P. M., 2018, In: Scientific Reports. 8, p. 1-9 16360.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial Aggregates Establish at the Edges of Acute Epidermal Wounds
Bay, Lene, Kragh, K. N., Eickhardt, S. R., Poulsen, Steen Seier, Gjerdrum, Lise Mette Rahbek, Ghathian, K., Calum, Henrik Pierre, Ågren, Magnus & Bjarnsholt, Thomas, Apr 2018, In: Advances in Wound Care. 7, 4, p. 105-113Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implants induce a new niche for microbiomes
Jakobsen, Tim Holm, Eickhardt, S. R., Gheorghe, Alexandra Gabriella, Stenqvist, C., Sønderholm, M., Stavnsberg, C., Jensen, Peter Østrup, Odgaard, Anders, Whiteley, M., Moser, Claus Ernst, Hvolris, J., Hougen, H. P. & Bjarnsholt, Thomas, 1 Aug 2018, In: APMIS - Journal of Pathology, Microbiology and Immunology. 126, 8, p. 685-692 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial biofilm formation inside colonic crypts may accelerate colorectal carcinogenesis
Raskov, H., Kragh, K. N., Bjarnsholt, Thomas, Alamili, M. & Gögenur, Ismail, 17 Sep 2018, In: Clinical and Translational Medicine. 7, 4 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Samspillet mellem mikrobiota og immunsystemet ved kolorektal cancer
Raskov, H., Bjarnsholt, Thomas, Alamili, M., Kragh, K. N. & Gögenur, Ismail, 5 Nov 2018, In: Ugeskrift for Laeger. 180, 45, V04180253.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
An equine wound model to study effects of bacterial aggregates on wound healing
Jørgensen, Elin , Bay, Lene, Skovgaard, Lene Theil, Bjarnsholt, Thomas & Jacobsen, Stine, 2019, In: Advances in Wound Care. 8, 10, p. 487-498Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of proximal bone margins in diabetic foot osteomyelitis by conventional culture, DNA sequencing and microscopy
Malone, M., Fritz, Blaine Gabriel, Vickery, K., Schwarzer, S., Sharma, V., Biggs, N., Radzieta, M., Jeffries, T. T., Dickson, H. G., Jensen, S. O. & Bjarnsholt, Thomas, 2019, In: APMIS. 127, 10, p. 660-670 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms
Crabbé, A., Jensen, Peter Østrup, Bjarnsholt, Thomas & Coenye, T., 2019, In: Trends in Microbiology. 27, 10, p. 850-863Research output: Contribution to journal › Review › Research › peer-review
- Published
Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth
Høiby, Niels, Henneberg, K. Å., Wang, H., Stavnsbjerg, Camilla, Bjarnsholt, Thomas, Ciofu, Oana, Johansen, U. R. & Sams, T., 2019, In: International Journal of Antimicrobial Agents. 53, 5, p. 564-573Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients
Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air
Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-Jepsen, Daniel, Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Situ Monitoring of the Antibacterial Activity of a Copper-Silver Alloy Using Confocal Laser Scanning Microscopy and pH Microsensors
Ciacotich, N., Kragh, K. N., Lichtenberg, Mads, Tesdorpf, J. E., Bjarnsholt, Thomas & Gram, L., 2019, In: Global Challenges. 3, 11, 9 p., 1900044.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo gentamicin susceptibility test for prevention of bacterial biofilms in bone tissue and on implants
Jensen, Louise Kruse, Bjarnsholt, Thomas, Kragh, K. N., Aalbæk, Bent, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie, Pankoke, K., Petersen, A. & Jensen, Henrik Elvang, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 2, 10 p., e01889-18.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Into the well—A close look at the complex structures of a microtiter biofilm and the crystal violet assay
Kragh, K. N., Alhede, M., Kvich, Lasse Andersson & Bjarnsholt, Thomas, 2019, In: Biofilm. 1, 9 p., 100006.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is pseudarthrosis after spinal instrumentation caused by a chronic infection?
Ohrt-Nissen, S., Fritz, Blaine Gabriel, Valentin, L., Kragh, K. N., Manniche, C., Dahl, B. & Bjarnsholt, Thomas, 2019, In: European Spine Journal. 28, p. 2996–3002Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxygen restriction generates difficult-to-culture p. Aeruginosa
Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Crone, S., Kragh, K. N., Kolpen, Mette, Sønderholm, M., Andersson, M., Koch, A., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2019, In: Frontiers in Microbiology. 10, AUG, 15 p., 1992.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction
Bjarnsholt, Thomas, Jensen, Peter Østrup & Alhede, M., 2019, In: Pathogens and Disease. 77, 5, ftz052.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shotgun sequencing of clinical biofilm following scanning electron microscopy identifies bacterial community composition
Fritz, Blaine Gabriel, Stavnsbjerg, Camilla, Markvart, Merete, Damgaard, P. D. B., Nielsen, Sofie Holtsmark, Bjørndal, Lars, Qvortrup, Klaus & Bjarnsholt, Thomas, 2019, In: Pathogens and Disease. 77, 1, 7 p., ftz013.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Understanding the microbiome of diabetic foot osteomyelitis: insights from molecular and microscopic approaches
Johani, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Lipsky, B. A., Jensen, S. O., Yang, M., Dean, A., Hu, H., Vickery, K. & Malone, M., 2019, In: Clinical Microbiology and Infection. 25, 3, p. 332-339Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Staphylococcus aureus augments release of matrix metalloproteinase-8 from human polymorphonuclear leukocytes
Kirketerp-Møller, K., Bjarnsholt, Thomas, Jensen, Peter Østrup & Ågren, Magnus, 2020, In: Acta Dermato-Venereologica. 100, 15, p. 1-2 2 p., adv00232.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic susceptibility of cystic fibrosis lung microbiome members in a multispecies biofilm
Vandeplassche, E., Sass, A., Ostyn, L., Burmølle, Mette, Kragh, K. N., Bjarnsholt, Thomas, Coenye, T. & Crabbé, A., 2020, In: Biofilm. 2, 9 p., 100031.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes
Alhede, M., Lorenz, M., Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, H. C., Bay, Lene & Bjarnsholt, Thomas, 2020, In: Medical Microbiology and Immunology. 209, p. 669–680Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation
Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Copper-Silver alloy coated door handles as a potential antibacterial strategy in clinical settings
Ciacotich, N., Kvich, Lasse Andersson, Sanford, N., Wolcott, J., Bjarnsholt, Thomas & Gram, L., 2020, In: Coatings. 10, 8, 9 p., 790.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do Mixed-Species Biofilms Dominate in Chronic Infections? Need for in situ Visualization of Bacterial Organization
Kvich, Lasse Andersson, Burmølle, Mette, Bjarnsholt, Thomas & Lichtenberg, Mads, 2020, In: Frontiers in Cellular and Infection Microbiology. 10, 12 p., 396.Research output: Contribution to journal › Review › Research › peer-review
- Published
Does an Antimicrobial Incision Drape Prevent Intraoperative Contamination? A Randomized Controlled Trial of 1187 Patients
Hesselvig, A. B., Arpi, M., Madsen, F., Bjarnsholt, Thomas, Odgaard, Anders & ICON Study Group, I. S. G., 2020, In: Clinical Orthopaedics and Related Research. 478, 5, p. 1007-1015Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology
Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eradication of biofilms on tympanostomy tubes with acetic acid treatment: an in vitro study
Kjeldsen, M., Homøe, Preben, Nielsen, Anne Kirstine, Crone, S., Nørskov Kragh, K. & Bjarnsholt, Thomas, 2020, In: APMIS. 128, 6, p. 445-450Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histologic changes and gene expression patterns in biopsy specimens from bacteria-inoculated and noninoculated excisional body and limb wounds in horses healing by second intention
Jørgensen, Elin , Hjerpe, F. B., Hougen, H. P., Bjarnsholt, Thomas, Berg, Lise Charlotte & Jacobsen, Stine, 2020, In: American Journal of Veterinary Research. 81, 3, p. 276-284 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9755066
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
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