Thomas Bjarnsholt
Professor
Bacteriology
Nørre Allé 14
2200 København N
- 2017
- Published
Diagnosis of biofilm infections in cystic fibrosis patients
Høiby, Niels, Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup, Kolpen, Mette, Qvist, T., Aanæs, Kasper, Pressler, T., Skov, M. & Ciofu, Oana, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 339-343 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Pseudomonas aeruginosa aggregate formation in an alginate bead model system exhibits In Vivo-like characteristics
Sønderholm, M., Kragh, K. N., Koren, K., Jakobsen, Tim Holm, Darch, S., Alhede, M., Jensen, Peter Østrup, Whiteley, M., Kühl, Michael & Bjarnsholt, Thomas, May 2017, In: Applied and Environmental Microbiology. 83, 9, 15 p., e00113-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The occurrence of biofilm in an equine experimental wound model of healing by secondary intention
Jørgensen, Elin , Bay, Lene, Bjarnsholt, Thomas, Bundgaard, L., Sørensen, M. A. & Jacobsen, Stine, May 2017, In: Veterinary Microbiology. 204, p. 90-95 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?
Jensen, Ramon Gordon, Johansen, Helle Krogh, Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R. & Homøe, Preben, Jul 2017, In: European Archives of Oto-Rhino-Laryngology. 274, 7, p. 2741-2747 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Consensus guidelines for the identification and treatment of biofilms in chronic nonhealing wounds
Schultz, G., Bjarnsholt, Thomas, James, G. A., Leaper, D. J., McBain, A. J., Malone, M., Stoodley, P., Swanson, T., Tachi, M. & Wolcott, R. D., Sep 2017, In: Wound Repair and Regeneration. 25, 5, p. 744-757 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
O-2 AFFECTS THE ACTIVITY OF AMIKACIN ON MYCOBACTERIUM ABSCESSUS BIOFILM
Kolpen, M., Ravnholt, C., Qvist, T., Kragh, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, Sep 2017, In: Pediatric Pulmonology. 52, S47, p. S359-S360 379.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Haematoxylin and eosin staining identifies medium to large bacterial aggregates with a reliable specificity: A comparative analysis of follicular bacterial aggregates in axillary biopsies using peptide nucleic acid-fluorescence in situ hybridization and haematoxylin and eosin staining
Ring, H. C., Riis, P. T., Bay, Lene, Kallenbach, K., Bjarnsholt, Thomas & Jemec, Gregor, Oct 2017, In: Experimental Dermatology. 26, 10, p. 943-945Research output: Contribution to journal › Letter › Research › peer-review
- Published
Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin
Kolpen, Mette, Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heading for centennial anniversary and beyond
Norrild, B., Ralfkiaer, E., Bjarnsholt, Thomas & Jensen, Peter Østrup, Dec 2017, In: APMIS. 125, 12, p. 1133-1133Research output: Contribution to journal › Editorial › Research
- 2018
- Published
Bacterial biofilms: a possible mechanism for chronic infection in patients with lumbar disc herniation - a prospective proof-of-concept study using fluorescence in situ hybridization
Ohrt-Nissen, S., Fritz, Blaine Gabriel, Walbom, J., Kragh, K. N., Bjarnsholt, Thomas, Dahl, Benny & Manniche, C., 2018, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 126, 5, p. 440-447 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilm formation – what we can learn from recent developments
Bjarnsholt, Thomas, Buhlin, K., Dufrêne, Y. F., Gomelsky, M., Moroni, A., Ramstedt, M., Rumbaugh, K. P., Schulte, T., Sun, L., Åkerlund, B. & Römling, U., 2018, In: Journal of Internal Medicine. 284, 4, p. 332-345 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Combined Staining Techniques for Demonstration of Staphylococcus aureus Biofilm in Routine Histopathology
Jensen, Louise Kruse, Henriksen, Nicole Lind, Bjarnsholt, Thomas, Kragh, K. N. & Jensen, Henrik Elvang, 2018, In: Journal of Bone and Joint Infection. 3, 1, p. 27-36Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In memoriam-Mark E. Shirtliff (1969-2018)
Coenye, T., Bjarnsholt, Thomas, Stoodley, P. & Rumbaugh, K., 2018, In: Pathogens and Disease. 76, 7, fty068.Research output: Contribution to journal › Editorial › Research
- Published
Inoculation method could impact the outcome of microbiological experiments
Kragh, K. N., Alhede, M., Rybtke, Morten Levin, Stavnsbjerg, Camilla, Tolker-Nielsen, Tim, Whiteley, M. & Bjarnsholt, Thomas, 2018, In: Applied and Environmental Microbiology. 84, 5, 14 p., e02264-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin
Woetmann, Anders , Alhede, M., Dabelsteen, Sally, Bjarnsholt, Thomas, Rybtke, Morten Levin, Nastasi, C., Krejsgaard, T., Andersen, Mads Hald, Bonefeld, Charlotte Menne, Geisler, Carsten, Givskov, Michael & Ødum, Niels, 2018, In: OncoTarget. 9, 28, p. 19481-19489 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Moderate to severe hidradenitis suppurativa patients do not have an altered bacterial composition in peripheral blood compared to healthy controls
Ring, H. C., Thorsen, Jonathan Jan Ilve, Saunte, Ditte Marie, Lilje, B., Bay, Lene, Theut Riis, P., Larsen, N., O'Brien Andersen, L., Vedel Nielsen, H., Miller, I. M., Bjarnsholt, Thomas, Fuursted, K. & Jemec, Gregor, 2018, In: Journal of the European Academy of Dermatology and Venereology. 32, 1, p. 125-128 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Morphological evidence of biofilm in chronic obstructive sialadenitis
Schrøder, S. A., Eickhardt, S., Bjarnsholt, Thomas, Nørgaard, T. & Homøe, Preben, 2018, In: Journal of Laryngology and Otology. 132, 7, p. 611-614 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa transcriptome during human infection
Cornforth, D. M., Dees, J. L., Ibberson, C. B., Huse, H. K., Mathiesen, I. H., Kirketerp-Møller, K., Wolcott, R. D., Rumbaugh, K. P., Bjarnsholt, Thomas & Whiteley, M., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 22, p. E5125-E5134Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Should standardized susceptibility testing for microbial biofilms be introduced in clinical practice?
Coenye, T., Goeres, D., Van Bambeke, F. & Bjarnsholt, Thomas, 2018, In: Clinical Microbiology and Infection. 24, 6, p. 570–572 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The use of fluorescent staining techniques for microscopic investigation of polymorphonuclear leukocytes and bacteria
Alhede, M., Stavnsbjerg, Camilla & Bjarnsholt, Thomas, 2018, In: APMIS. 126, 10, p. 779-794 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model
Sønderholm, M., Koren, K., Wangpraseurt, D., Jensen, Peter Østrup, Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas & Kühl, Michael, 2018, In: npj Biofilms and Microbiomes. 4, 11 p., 3.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV light assisted antibiotics for eradication of in vitro biofilms
Argyraki, A., Markvart, Merete, Stavnsbjerg, Camilla, Kragh, K. N., Ou, Y., Bjørndal, Lars, Bjarnsholt, Thomas & Petersen, P. M., 2018, In: Scientific Reports. 8, p. 1-9 16360.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial Aggregates Establish at the Edges of Acute Epidermal Wounds
Bay, Lene, Kragh, K. N., Eickhardt, S. R., Poulsen, Steen Seier, Gjerdrum, Lise Mette Rahbek, Ghathian, K., Calum, Henrik Pierre, Ågren, Magnus & Bjarnsholt, Thomas, Apr 2018, In: Advances in Wound Care. 7, 4, p. 105-113Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implants induce a new niche for microbiomes
Jakobsen, Tim Holm, Eickhardt, S. R., Gheorghe, Alexandra Gabriella, Stenqvist, C., Sønderholm, M., Stavnsberg, C., Jensen, Peter Østrup, Odgaard, Anders, Whiteley, M., Moser, Claus Ernst, Hvolris, J., Hougen, H. P. & Bjarnsholt, Thomas, 1 Aug 2018, In: APMIS - Journal of Pathology, Microbiology and Immunology. 126, 8, p. 685-692 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial biofilm formation inside colonic crypts may accelerate colorectal carcinogenesis
Raskov, H., Kragh, K. N., Bjarnsholt, Thomas, Alamili, M. & Gögenur, Ismail, 17 Sep 2018, In: Clinical and Translational Medicine. 7, 4 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Samspillet mellem mikrobiota og immunsystemet ved kolorektal cancer
Raskov, H., Bjarnsholt, Thomas, Alamili, M., Kragh, K. N. & Gögenur, Ismail, 5 Nov 2018, In: Ugeskrift for Laeger. 180, 45, V04180253.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
An equine wound model to study effects of bacterial aggregates on wound healing
Jørgensen, Elin , Bay, Lene, Skovgaard, Lene Theil, Bjarnsholt, Thomas & Jacobsen, Stine, 2019, In: Advances in Wound Care. 8, 10, p. 487-498Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of proximal bone margins in diabetic foot osteomyelitis by conventional culture, DNA sequencing and microscopy
Malone, M., Fritz, Blaine Gabriel, Vickery, K., Schwarzer, S., Sharma, V., Biggs, N., Radzieta, M., Jeffries, T. T., Dickson, H. G., Jensen, S. O. & Bjarnsholt, Thomas, 2019, In: APMIS. 127, 10, p. 660-670 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms
Crabbé, A., Jensen, Peter Østrup, Bjarnsholt, Thomas & Coenye, T., 2019, In: Trends in Microbiology. 27, 10, p. 850-863Research output: Contribution to journal › Review › Research › peer-review
- Published
Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth
Høiby, Niels, Henneberg, K. Å., Wang, H., Stavnsbjerg, Camilla, Bjarnsholt, Thomas, Ciofu, Oana, Johansen, U. R. & Sams, T., 2019, In: International Journal of Antimicrobial Agents. 53, 5, p. 564-573Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients
Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air
Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-Jepsen, Daniel, Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Situ Monitoring of the Antibacterial Activity of a Copper-Silver Alloy Using Confocal Laser Scanning Microscopy and pH Microsensors
Ciacotich, N., Kragh, K. N., Lichtenberg, Mads, Tesdorpf, J. E., Bjarnsholt, Thomas & Gram, L., 2019, In: Global Challenges. 3, 11, 9 p., 1900044.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo gentamicin susceptibility test for prevention of bacterial biofilms in bone tissue and on implants
Jensen, Louise Kruse, Bjarnsholt, Thomas, Kragh, K. N., Aalbæk, Bent, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie, Pankoke, K., Petersen, A. & Jensen, Henrik Elvang, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 2, 10 p., e01889-18.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Into the well—A close look at the complex structures of a microtiter biofilm and the crystal violet assay
Kragh, K. N., Alhede, M., Kvich, Lasse Andersson & Bjarnsholt, Thomas, 2019, In: Biofilm. 1, 9 p., 100006.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is pseudarthrosis after spinal instrumentation caused by a chronic infection?
Ohrt-Nissen, S., Fritz, Blaine Gabriel, Valentin, L., Kragh, K. N., Manniche, C., Dahl, B. & Bjarnsholt, Thomas, 2019, In: European Spine Journal. 28, p. 2996–3002Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxygen restriction generates difficult-to-culture p. Aeruginosa
Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Crone, S., Kragh, K. N., Kolpen, Mette, Sønderholm, M., Andersson, M., Koch, A., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2019, In: Frontiers in Microbiology. 10, AUG, 15 p., 1992.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction
Bjarnsholt, Thomas, Jensen, Peter Østrup & Alhede, M., 2019, In: Pathogens and Disease. 77, 5, ftz052.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shotgun sequencing of clinical biofilm following scanning electron microscopy identifies bacterial community composition
Fritz, Blaine Gabriel, Stavnsbjerg, Camilla, Markvart, Merete, Damgaard, P. D. B., Nielsen, Sofie Holtsmark, Bjørndal, Lars, Qvortrup, Klaus & Bjarnsholt, Thomas, 2019, In: Pathogens and Disease. 77, 1, 7 p., ftz013.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Understanding the microbiome of diabetic foot osteomyelitis: insights from molecular and microscopic approaches
Johani, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Lipsky, B. A., Jensen, S. O., Yang, M., Dean, A., Hu, H., Vickery, K. & Malone, M., 2019, In: Clinical Microbiology and Infection. 25, 3, p. 332-339Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Staphylococcus aureus augments release of matrix metalloproteinase-8 from human polymorphonuclear leukocytes
Kirketerp-Møller, K., Bjarnsholt, Thomas, Jensen, Peter Østrup & Ågren, Magnus, 2020, In: Acta Dermato-Venereologica. 100, 15, p. 1-2 2 p., adv00232.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic susceptibility of cystic fibrosis lung microbiome members in a multispecies biofilm
Vandeplassche, E., Sass, A., Ostyn, L., Burmølle, Mette, Kragh, K. N., Bjarnsholt, Thomas, Coenye, T. & Crabbé, A., 2020, In: Biofilm. 2, 9 p., 100031.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes
Alhede, M., Lorenz, M., Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, H. C., Bay, Lene & Bjarnsholt, Thomas, 2020, In: Medical Microbiology and Immunology. 209, p. 669–680Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation
Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Copper-Silver alloy coated door handles as a potential antibacterial strategy in clinical settings
Ciacotich, N., Kvich, Lasse Andersson, Sanford, N., Wolcott, J., Bjarnsholt, Thomas & Gram, L., 2020, In: Coatings. 10, 8, 9 p., 790.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do Mixed-Species Biofilms Dominate in Chronic Infections? Need for in situ Visualization of Bacterial Organization
Kvich, Lasse Andersson, Burmølle, Mette, Bjarnsholt, Thomas & Lichtenberg, Mads, 2020, In: Frontiers in Cellular and Infection Microbiology. 10, 12 p., 396.Research output: Contribution to journal › Review › Research › peer-review
- Published
Does an Antimicrobial Incision Drape Prevent Intraoperative Contamination? A Randomized Controlled Trial of 1187 Patients
Hesselvig, A. B., Arpi, M., Madsen, F., Bjarnsholt, Thomas, Odgaard, Anders & ICON Study Group, I. S. G., 2020, In: Clinical Orthopaedics and Related Research. 478, 5, p. 1007-1015Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology
Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eradication of biofilms on tympanostomy tubes with acetic acid treatment: an in vitro study
Kjeldsen, M., Homøe, Preben, Nielsen, Anne Kirstine, Crone, S., Nørskov Kragh, K. & Bjarnsholt, Thomas, 2020, In: APMIS. 128, 6, p. 445-450Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histologic changes and gene expression patterns in biopsy specimens from bacteria-inoculated and noninoculated excisional body and limb wounds in horses healing by second intention
Jørgensen, Elin , Hjerpe, F. B., Hougen, H. P., Bjarnsholt, Thomas, Berg, Lise Charlotte & Jacobsen, Stine, 2020, In: American Journal of Veterinary Research. 81, 3, p. 276-284 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9755066
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
Research output: Contribution to journal › Journal article › Research › peer-review
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
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