Thomas Eiland Nielsen

Thomas Eiland Nielsen

Affiliate Professor


  1. 2011
  2. Published

    A convenient procedure for the solid-phase synthesis of hydroxamic acids on PEGA resins

    Nandurkar, N. S., Petersen, R., Qvortrup, K., Komnatnyy, V. V., Taveras, K. M., Le Quement, S. T., Frauenlob, R., Givskov, Michael & Nielsen, Thomas Eiland, 28 Dec 2011, In: Tetrahedron Letters. 52, 52, p. 7121-7124 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2013
  4. Published

    Identification of five structurally unrelated quorum-sensing inhibitors of Pseudomonas aeruginosa from a natural-derivative database

    Tan, S. Y. Y., Chua, S. L., Chen, Y., Rice, S. A., Kjelleberg, S., Nielsen, Thomas Eiland, Yang, L. & Givskov, Michael, Nov 2013, In: Antimicrobial Agents and Chemotherapy. 57, 11, p. 5629-5641 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2014
  6. Published

    Synthesis of 4-halogenated 3-fluoro-6-methoxyquinolines: Key building blocks for the synthesis of antibiotics

    Flagstad, T., Petersen, M. T., Hinnerfeldt, D. M., Givskov, Michael & Nielsen, Thomas Eiland, 28 Aug 2014, In: Synthesis (Germany). 46, 23, p. 3263-3267 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2015
  8. Published

    In vitro and in vivo generation and characterization of Pseudomonas aeruginosa biofilm-dispersed cells via c-di-GMP manipulation

    Chua, S. L., Hultqvist, Louise Dahl, Yuan, M., Rybtke, Morten Levin, Nielsen, Thomas Eiland, Givskov, Michael, Tolker-Nielsen, Tim & Yang, L., Aug 2015, In: Nature Protocols (Print). 10, 8, p. 1165-80 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2016
  10. Published

    The anti-cancerous drug doxorubicin decreases the c-di-GMP content in Pseudomonas aeruginosa but promotes biofilm formation

    Groizeleau, J., Rybtke, Morten Levin, Andersen, Jens Bo, Berthelsen, J., Liu, Y., Yang, L., Nielsen, Thomas Eiland, Kaever, V., Givskov, Michael & Tolker-Nielsen, Tim, 1 Oct 2016, In: Microbiology. 162, 10, p. 1797-1807 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2017
  12. Published

    A Linker for the Solid-Phase Synthesis of Hydroxamic Acids and Identification of HDAC6 Inhibitors

    Bang, C. G., Jensen, J. F., O'Hanlon Cohrt, E., Olsen, L. B., Siyum, S. G., Mortensen, K. T., Skovgaard, T., Berthelsen, J., Yang, L., Givskov, Michael, Qvortrup, K. & Nielsen, Thomas Eiland, Oct 2017, In: ACS Combinatorial Science. 19, 10, p. 657-669 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Synergy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Inhibiting P.aeruginosa Quorum Sensing

    Fong, J., Zhang, C., Yang, R., Boo, Z. Z., Tan, S. K., Nielsen, Thomas Eiland, Givskov, Michael, Wu, B., Su, H. & Yang, L., 2017, bioRxiv, 27 p.

    Research output: Working paperPreprintResearch

  14. Published

    Disulfide Bond-Containing Ajoene Analogues As Novel Quorum Sensing Inhibitors of Pseudomonas aeruginosa

    Fong, J., Yuan, M., Jakobsen, Tim Holm, Mortensen, K. T., Delos Santos, M. M. S., Chua, S. L., Yang, L., Tan, C. H., Nielsen, Thomas Eiland & Givskov, Michael, 12 Jan 2017, In: Journal of Medicinal Chemistry. 60, 1, p. 215-227

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Diastereoselective synthesis of novel heterocyclic scaffolds through tandem Petasis 3-component/intramolecular Diels-Alder and ROM-RCM reactions

    Ishoey, M., Petersen, R. G., Petersen, M. A., Wu, P., Clausen, M. H. & Nielsen, Thomas Eiland, 2017, In: Chemical Communications. 53, 68, p. 9410-9413

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A broad range quorum sensing inhibitor working through sRNA inhibition

    Jakobsen, Tim Holm, Warming, A. N., Vejborg, R. M., Moscoso, J. A., Stegger, M., Lorenzen, F., Rybtke, Morten Levin, Andersen, Jens Bo, Petersen, R., Andersen, P. S., Nielsen, Thomas Eiland, Tolker-Nielsen, Tim, Filloux, A., Ingmer, Hanne & Givskov, Michael, 2017, In: Scientific Reports. 7, 1, 12 p., 9857.

    Research output: Contribution to journalJournal articleResearchpeer-review

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