Tim Holm Jakobsen
Associate Professor
Bacteriology
Nørre Allé 14
2200 København N
- Published
Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors
Jakobsen, Tim Holm, Bjarnsholt, Thomas, Jensen, Peter Østrup, Givskov, Michael & Høiby, Niels, Jul 2013, In: Future Microbiology. 8, 7, p. 901-21 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa
Jakobsen, Tim Holm, Bragason, S. K., Phipps, R. K., Hultqvist, Louise Dahl, van Gennip, M., Alhede, M., Skindersoe, M., Larsen, T. O., Høiby, Niels, Bjarnsholt, Thomas & Givskov, Michael, 2012, In: Applied and Environmental Microbiology. 78, 7, p. 2410-2421 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing
Jakobsen, Tim Holm, van Gennip, M., Phipps, R. K., Shanmugham, M. S., Hultqvist, Louise Dahl, Alhede, M., Skindersoe, M. E., Rasmussen, T. B., Friedrich, K., Uthe, F., Jensen, Peter Østrup, Moser, Claus Ernst, Nielsen, Kristian Fog, Eberl, L., Larsen, T. O., Tanner, D. A., Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., May 2012, In: Antimicrobial Agents and Chemotherapy. 56, 5, p. 2314-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SAR study of 4-arylazo-3,5-diamino-1: H -pyrazoles: identification of small molecules that induce dispersal of Pseudomonas aeruginosa biofilms
Jansen, C. U., Uhd, J., Andersen, Jens Bo, Hultqvist, Louise Dahl, Jakobsen, Tim Holm, Nilsson, Carl Martin Peter, Nielsen, Thomas Eiland, Givskov, Michael, Tolker-Nielsen, Tim & Qvortrup, K. M., 2021, In: RSC Medicinal Chemistry. 12, 11, p. 1868-1878 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chemical Regulation of Pseudomonas aeruginosa Biofilm Formation as a Potential Treatment for Persistent Infections
Kristensen, Rasmus, Tolker-Nielsen, Tim & Jakobsen, Tim Holm, 2022, Antibiofilm Strategies: Current and Future Applications to Prevent, Control and Eradicate Biofilms. Springer, p. 159-179 (Springer Series on Biofilms; No. 11).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Inhibition of Pseudomonas aeruginosa quorum sensing by chemical induction of the MexEF-oprN efflux pump
Kristensen, Rasmus, Andersen, Jens Bo, Rybtke, Morten Levin, Jansen, C. U., Fritz, Blaine Gabriel, Kiilerich, R. O., Uhd, J., Bjarnsholt, Thomas, Qvortrup, K., Tolker-Nielsen, Tim, Givskov, Michael & Jakobsen, Tim Holm, 2024, In: Antimicrobial Agents and Chemotherapy. 68, 2Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Single cells and bacterial biofilm populations in chronic wound infections
Lichtenberg, Mads, Kirketerp-Møller, K., Kvich, Lasse Andersson, Christensen, Mads Holm, Fritz, Blaine Gabriel, Jakobsen, Tim Holm & Bjarnsholt, Thomas, 2024, (E-pub ahead of print) In: APMIS.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
What's in a name? Characteristics of clinical biofilms
Lichtenberg, Mads, Coenye, T., Parsek, M. R., Bjarnsholt, Thomas & Jakobsen, Tim Holm, 2023, In: FEMS Microbiology Reviews. 47, 5, p. 1-8 fuad050.Research output: Contribution to journal › Review › Research › peer-review
- Published
Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa
Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, Morten Levin, Toyofuku, M., Nomura, N., Kolpen, Mette, Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inoculum Concentration Influences Pseudomonas aeruginosa Phenotype and Biofilm Architecture
Lichtenberg, Mads, Kvich, Lasse Andersson, Larsen, S. L. B., Jakobsen, Tim Holm & Bjarnsholt, Thomas, 2022, In: Microbiology Spectrum. 10, 6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment
Lichtenberg, Mads, Jakobsen, Tim Holm, Kühl, Michael, Kolpen, Mette, Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: FEMS Microbiology Reviews. 46, 5, 13 p., fuac018.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidative stress response plays a role in antibiotic tolerance of Streptococcus mutans biofilms
Nilsson, Carl Martin Peter, Jakobsen, Tim Holm, Givskov, Michael, Twetman, Svante & Tolker-Nielsen, Tim, 2019, In: Microbiology. 165, 3, p. 334-342Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small Molecule Anti-biofilm Agents Developed on the Basis of Mechanistic Understanding of Biofilm Formation
Qvortrup, K., Hultqvist, Louise Dahl, Nilsson, Carl Martin Peter, Jakobsen, Tim Holm, Jansen, C. U., Uhd, J., Andersen, Jens Bo, Nielsen, Thomas Eiland, Givskov, Michael & Tolker-Nielsen, Tim, 2019, In: Frontiers in Chemistry. 7, 27 p., 742.Research output: Contribution to journal › Review › Research › peer-review
- Published
Identification of LasR ligands through a virtual screening approach
Skovstrup, S., Le Quement, S. T., Hansen, T., Jakobsen, Tim Holm, Harmsen, M., Tolker-Nielsen, Tim, Nielsen, T. E., Givskov, Michael & Taboureau, O., 2013, In: ChemMedChem. 8, 1, p. 157-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa aggregate formation in an alginate bead model system exhibits In Vivo-like characteristics
Sønderholm, M., Kragh, K. N., Koren, K., Jakobsen, Tim Holm, Darch, S., Alhede, M., Jensen, Peter Østrup, Whiteley, M., Kühl, Michael & Bjarnsholt, Thomas, May 2017, In: Applied and Environmental Microbiology. 83, 9, 15 p., e00113-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative systems biology analysis to study the mode of action of the isothiocyanate compound Iberin on Pseudomonas aeruginosa
Tan, S. Y., Liu, Y., Chua, S. L., Vejborg, R. M., Jakobsen, Tim Holm, Chew, S. C., Li, Y., Nielsen, T. E., Tolker-Nielsen, Tim, Yang, L. & Givskov, Michael, Nov 2014, In: Antimicrobial Agents and Chemotherapy. 58, 11, p. 6648-59 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilm Survival Strategies in Chronic Wounds
Thaarup, Ida Clement, Iversen, A. K. S., Lichtenberg, Mads, Bjarnsholt, Thomas & Jakobsen, Tim Holm, 2022, In: Microorganisms. 10, 4, 775.Research output: Contribution to journal › Review › Research › peer-review
- Published
Fusaric acid and analogues as gram-negative bacterial quorum sensing inhibitors
Thanh Tung, T., Jakobsen, Tim Holm, Dao, T. T., Fuglsang, Anja Thoe, Givskov, Michael, Christensen, Søren Brøgger & Nielsen, J., 2017, In: European Journal of Medicinal Chemistry. 126, p. 1011-1020 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computer-aided identification of recognized drugs as Pseudomonas aeruginosa quorum-sensing inhibitors
Yang, L., Rybtke, Morten Levin, Jakobsen, Tim Holm, Hentzer, M., Bjarnsholt, Thomas, Givskov, Michael & Tolker-Nielsen, Tim, 2009, In: Antimicrobial Agents and Chemotherapy. 53, 6, p. 2432-43 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synergistic bactericidal effect of nisin and phytic acid against Escherichia coli O157:H7
Zhao, G., Kempen, Paul Joseph, Zheng, T., Jakobsen, Tim Holm, Zhao, S., Gu, L., Solem, C. & Ruhdal Jensen, P., 2023, In: Food Control. 144, 109324.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9840851
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes
Research output: Contribution to journal › Review › Research › peer-review
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264
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Pseudomonas aeruginosa aggregate formation in an alginate bead model system exhibits In Vivo-like characteristics
Research output: Contribution to journal › Journal article › Research › peer-review
Published