Detection of Pathogenic Biofilms with Bacterial Amyloid Targeting Fluorescent Probe, CDy11

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Detection of Pathogenic Biofilms with Bacterial Amyloid Targeting Fluorescent Probe, CDy11. / Kim, Jun Young; Sahu, Srikanta; Yau, Yin Hoe; Wang, Xu; Shochat, Susana Geifman; Nielsen, Per Halkjær; Dueholm, Morten Simonsen; Otzen, Daniel E.; Lee, Jungyeol; Delos Santos, May Margarette Salido; Yam, Joey Kuok Hoong; Kang, Nam Young; Park, Sung Jin; Kwon, Hawyoung; Seviour, Thomas; Yang, Liang; Givskov, Michael; Chang, Young Tae.

In: Journal of the American Chemical Society, Vol. 138, No. 1, 13.01.2016, p. 402-407.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Kim, JY, Sahu, S, Yau, YH, Wang, X, Shochat, SG, Nielsen, PH, Dueholm, MS, Otzen, DE, Lee, J, Delos Santos, MMS, Yam, JKH, Kang, NY, Park, SJ, Kwon, H, Seviour, T, Yang, L, Givskov, M & Chang, YT 2016, 'Detection of Pathogenic Biofilms with Bacterial Amyloid Targeting Fluorescent Probe, CDy11', Journal of the American Chemical Society, vol. 138, no. 1, pp. 402-407. https://doi.org/10.1021/jacs.5b11357

APA

Kim, J. Y., Sahu, S., Yau, Y. H., Wang, X., Shochat, S. G., Nielsen, P. H., Dueholm, M. S., Otzen, D. E., Lee, J., Delos Santos, M. M. S., Yam, J. K. H., Kang, N. Y., Park, S. J., Kwon, H., Seviour, T., Yang, L., Givskov, M., & Chang, Y. T. (2016). Detection of Pathogenic Biofilms with Bacterial Amyloid Targeting Fluorescent Probe, CDy11. Journal of the American Chemical Society, 138(1), 402-407. https://doi.org/10.1021/jacs.5b11357

Vancouver

Kim JY, Sahu S, Yau YH, Wang X, Shochat SG, Nielsen PH et al. Detection of Pathogenic Biofilms with Bacterial Amyloid Targeting Fluorescent Probe, CDy11. Journal of the American Chemical Society. 2016 Jan 13;138(1):402-407. https://doi.org/10.1021/jacs.5b11357

Author

Kim, Jun Young ; Sahu, Srikanta ; Yau, Yin Hoe ; Wang, Xu ; Shochat, Susana Geifman ; Nielsen, Per Halkjær ; Dueholm, Morten Simonsen ; Otzen, Daniel E. ; Lee, Jungyeol ; Delos Santos, May Margarette Salido ; Yam, Joey Kuok Hoong ; Kang, Nam Young ; Park, Sung Jin ; Kwon, Hawyoung ; Seviour, Thomas ; Yang, Liang ; Givskov, Michael ; Chang, Young Tae. / Detection of Pathogenic Biofilms with Bacterial Amyloid Targeting Fluorescent Probe, CDy11. In: Journal of the American Chemical Society. 2016 ; Vol. 138, No. 1. pp. 402-407.

Bibtex

@article{4e80994c808046258c457c07a95cb69f,
title = "Detection of Pathogenic Biofilms with Bacterial Amyloid Targeting Fluorescent Probe, CDy11",
abstract = "Bacterial biofilms are responsible for a wide range of persistent infections. In the clinic, diagnosis of biofilm-associated infections relies heavily on culturing methods, which fail to detect nonculturable bacteria. Identification of novel fluorescent probes for biofilm imaging will greatly facilitate diagnosis of pathogenic bacterial infection. Herein, we report a novel fluorescent probe, CDy11 (compound of designation yellow 11), which targets amyloid in the Pseudomonas aeruginosa biofilm matrix through a diversity oriented fluorescent library approach (DOFLA). CDy11 was further demonstrated for in vivo imaging of P. aeruginosa in implant and corneal infection mice models.",
author = "Kim, {Jun Young} and Srikanta Sahu and Yau, {Yin Hoe} and Xu Wang and Shochat, {Susana Geifman} and Nielsen, {Per Halkj{\ae}r} and Dueholm, {Morten Simonsen} and Otzen, {Daniel E.} and Jungyeol Lee and {Delos Santos}, {May Margarette Salido} and Yam, {Joey Kuok Hoong} and Kang, {Nam Young} and Park, {Sung Jin} and Hawyoung Kwon and Thomas Seviour and Liang Yang and Michael Givskov and Chang, {Young Tae}",
year = "2016",
month = jan,
day = "13",
doi = "10.1021/jacs.5b11357",
language = "English",
volume = "138",
pages = "402--407",
journal = "Journal of the American Chemical Society",
issn = "0002-7863",
publisher = "ACS Publications",
number = "1",

}

RIS

TY - JOUR

T1 - Detection of Pathogenic Biofilms with Bacterial Amyloid Targeting Fluorescent Probe, CDy11

AU - Kim, Jun Young

AU - Sahu, Srikanta

AU - Yau, Yin Hoe

AU - Wang, Xu

AU - Shochat, Susana Geifman

AU - Nielsen, Per Halkjær

AU - Dueholm, Morten Simonsen

AU - Otzen, Daniel E.

AU - Lee, Jungyeol

AU - Delos Santos, May Margarette Salido

AU - Yam, Joey Kuok Hoong

AU - Kang, Nam Young

AU - Park, Sung Jin

AU - Kwon, Hawyoung

AU - Seviour, Thomas

AU - Yang, Liang

AU - Givskov, Michael

AU - Chang, Young Tae

PY - 2016/1/13

Y1 - 2016/1/13

N2 - Bacterial biofilms are responsible for a wide range of persistent infections. In the clinic, diagnosis of biofilm-associated infections relies heavily on culturing methods, which fail to detect nonculturable bacteria. Identification of novel fluorescent probes for biofilm imaging will greatly facilitate diagnosis of pathogenic bacterial infection. Herein, we report a novel fluorescent probe, CDy11 (compound of designation yellow 11), which targets amyloid in the Pseudomonas aeruginosa biofilm matrix through a diversity oriented fluorescent library approach (DOFLA). CDy11 was further demonstrated for in vivo imaging of P. aeruginosa in implant and corneal infection mice models.

AB - Bacterial biofilms are responsible for a wide range of persistent infections. In the clinic, diagnosis of biofilm-associated infections relies heavily on culturing methods, which fail to detect nonculturable bacteria. Identification of novel fluorescent probes for biofilm imaging will greatly facilitate diagnosis of pathogenic bacterial infection. Herein, we report a novel fluorescent probe, CDy11 (compound of designation yellow 11), which targets amyloid in the Pseudomonas aeruginosa biofilm matrix through a diversity oriented fluorescent library approach (DOFLA). CDy11 was further demonstrated for in vivo imaging of P. aeruginosa in implant and corneal infection mice models.

U2 - 10.1021/jacs.5b11357

DO - 10.1021/jacs.5b11357

M3 - Journal article

C2 - 26684612

AN - SCOPUS:84954342145

VL - 138

SP - 402

EP - 407

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

SN - 0002-7863

IS - 1

ER -

ID: 168876732