Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling
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Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling. / Givskov, M; de Nys, R; Manefield, M; Gram, L; Maximilien, R; Eberl, Leo; Molin, Søren; Steinberg, P D; Kjelleberg, S.
In: Journal of Bacteriology, Vol. 178, No. 22, 1996, p. 6618-22.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling
AU - Givskov, M
AU - de Nys, R
AU - Manefield, M
AU - Gram, L
AU - Maximilien, R
AU - Eberl, Leo
AU - Molin, Søren
AU - Steinberg, P D
AU - Kjelleberg, S
PY - 1996
Y1 - 1996
N2 - Acylated homoserine lactones (AHLs) play a widespread role in intercellular communication among bacteria. The Australian macroalga Delisea pulchra produces secondary metabolites which have structural similarities to AHL molecules. We report here that these metabolites inhibited AHL-controlled processes in prokaryotes. Our results suggest that the interaction between higher organisms and their surface-associated bacteria may be mediated by interference with bacterial regulatory systems.
AB - Acylated homoserine lactones (AHLs) play a widespread role in intercellular communication among bacteria. The Australian macroalga Delisea pulchra produces secondary metabolites which have structural similarities to AHL molecules. We report here that these metabolites inhibited AHL-controlled processes in prokaryotes. Our results suggest that the interaction between higher organisms and their surface-associated bacteria may be mediated by interference with bacterial regulatory systems.
M3 - Journal article
C2 - 8932319
VL - 178
SP - 6618
EP - 6622
JO - Journal of Bacteriology
JF - Journal of Bacteriology
SN - 0021-9193
IS - 22
ER -
ID: 44309661