Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.

Research output: Contribution to journalJournal articleResearchpeer-review

Biofilms are structured consortia of bacteria embedded in self-produced polymer matrix. Biofilms are resistant to antibiotics, disinfectives and phagocytosis. The persistence of foreign body infections is due to biofilms. Chronic P. aeruginosa lung infection in cystic fibrosis patients is a biofilm. Bacteria in biofilms communicate by means of quorum sensing which activates genes for virulence factors. Biofilms can be prevented by antibiotic prophylaxis or early therapy or by quorum sensing inhibitors which make them susceptible to antibiotics and phagocytosis.
Udgivelsesdato: 2007-Nov-26
Translated title of the contributionForeign body infections--biofilms and quorum sensing
Original languageDanish
JournalUgeskrift for læger
Issue number48
Pages (from-to)4163-6
Number of pages3
Publication statusPublished - 2007

Bibliographical note

Keywords: Anti-Bacterial Agents; Antibiotic Prophylaxis; Biofilms; Drug Resistance, Bacterial; Foreign-Body Reaction; Humans; Infection Control; Pseudomonas Infections; Pseudomonas aeruginosa; Quorum Sensing

ID: 8744681