Induction of beta-lactamase production in Pseudomonas aeruginosa biofilm
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Induction of beta-lactamase production in Pseudomonas aeruginosa biofilm. / Giwercman, B; Jensen, E T; Høiby, N; Kharazmi, A; Costerton, J W.
In: Antimicrobial Agents and Chemotherapy, Vol. 35, No. 5, 1991, p. 1008-10.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Induction of beta-lactamase production in Pseudomonas aeruginosa biofilm
AU - Giwercman, B
AU - Jensen, E T
AU - Høiby, N
AU - Kharazmi, A
AU - Costerton, J W
N1 - Keywords: Culture Media; Enzyme Induction; Hydrogen-Ion Concentration; Imipenem; Microbial Sensitivity Tests; Piperacillin; Pseudomonas aeruginosa; beta-Lactamases
PY - 1991
Y1 - 1991
N2 - Imipenem induced high levels of beta-lactamase production in Pseudomonas aeruginosa biofilms. Piperacillin also induced beta-lactamase production in these biofilms but to a lesser degree. The combination of beta-lactamase production with other protective properties of the biofilm mode of growth could be a major reason for the persistence of this sessile bacterium in chronic infections.
AB - Imipenem induced high levels of beta-lactamase production in Pseudomonas aeruginosa biofilms. Piperacillin also induced beta-lactamase production in these biofilms but to a lesser degree. The combination of beta-lactamase production with other protective properties of the biofilm mode of growth could be a major reason for the persistence of this sessile bacterium in chronic infections.
M3 - Journal article
C2 - 1906694
VL - 35
SP - 1008
EP - 1010
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 5
ER -
ID: 18177809