Induction of beta-lactamase production in Pseudomonas aeruginosa biofilm
Research output: Contribution to journal › Journal article › Research › peer-review
Imipenem induced high levels of beta-lactamase production in Pseudomonas aeruginosa biofilms. Piperacillin also induced beta-lactamase production in these biofilms but to a lesser degree. The combination of beta-lactamase production with other protective properties of the biofilm mode of growth could be a major reason for the persistence of this sessile bacterium in chronic infections.
| Original language | English |
|---|---|
| Journal | Antimicrobial Agents and Chemotherapy |
| Volume | 35 |
| Issue number | 5 |
| Pages (from-to) | 1008-10 |
| Number of pages | 2 |
| ISSN | 0066-4804 |
| Publication status | Published - 1991 |
Bibliographical note
Keywords: Culture Media; Enzyme Induction; Hydrogen-Ion Concentration; Imipenem; Microbial Sensitivity Tests; Piperacillin; Pseudomonas aeruginosa; beta-Lactamases
ID: 18177809