Petasis three-component coupling reactions of hydrazides for the synthesis of oxadiazolones and oxazolidinones

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Petasis three-component coupling reactions of hydrazides for the synthesis of oxadiazolones and oxazolidinones. / Le Quement, Sebastian T; Flagstad, Thomas; Mikkelsen, Remi J T; Hansen, Mette R; Givskov, Michael; Nielsen, Thomas E.

In: Organic Letters, Vol. 14, No. 2, 2012, p. 640-643.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Le Quement, ST, Flagstad, T, Mikkelsen, RJT, Hansen, MR, Givskov, M & Nielsen, TE 2012, 'Petasis three-component coupling reactions of hydrazides for the synthesis of oxadiazolones and oxazolidinones', Organic Letters, vol. 14, no. 2, pp. 640-643. https://doi.org/10.1021/ol203280b

APA

Le Quement, S. T., Flagstad, T., Mikkelsen, R. J. T., Hansen, M. R., Givskov, M., & Nielsen, T. E. (2012). Petasis three-component coupling reactions of hydrazides for the synthesis of oxadiazolones and oxazolidinones. Organic Letters, 14(2), 640-643. https://doi.org/10.1021/ol203280b

Vancouver

Le Quement ST, Flagstad T, Mikkelsen RJT, Hansen MR, Givskov M, Nielsen TE. Petasis three-component coupling reactions of hydrazides for the synthesis of oxadiazolones and oxazolidinones. Organic Letters. 2012;14(2):640-643. https://doi.org/10.1021/ol203280b

Author

Le Quement, Sebastian T ; Flagstad, Thomas ; Mikkelsen, Remi J T ; Hansen, Mette R ; Givskov, Michael ; Nielsen, Thomas E. / Petasis three-component coupling reactions of hydrazides for the synthesis of oxadiazolones and oxazolidinones. In: Organic Letters. 2012 ; Vol. 14, No. 2. pp. 640-643.

Bibtex

@article{49b346e8a2d1481fa5ddabf2ecfef57d,
title = "Petasis three-component coupling reactions of hydrazides for the synthesis of oxadiazolones and oxazolidinones",
abstract = "An application of readily available hydrazides in the Petasis 3-component coupling reaction is presented. An investigation of the substrate scope was performed to establish a general, synthetically useful protocol for the formation of hydrazido alcohols, which were selectively converted to oxazolidinone and oxadiazolone ring systems through triphosgene-mediated cyclization reactions.",
keywords = "Aldehydes, Cyclization, Hydrazines, Molecular Structure, Oxazolidinones",
author = "{Le Quement}, {Sebastian T} and Thomas Flagstad and Mikkelsen, {Remi J T} and Hansen, {Mette R} and Michael Givskov and Nielsen, {Thomas E}",
note = "{\textcopyright} 2012 American Chemical Society",
year = "2012",
doi = "10.1021/ol203280b",
language = "English",
volume = "14",
pages = "640--643",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "2",

}

RIS

TY - JOUR

T1 - Petasis three-component coupling reactions of hydrazides for the synthesis of oxadiazolones and oxazolidinones

AU - Le Quement, Sebastian T

AU - Flagstad, Thomas

AU - Mikkelsen, Remi J T

AU - Hansen, Mette R

AU - Givskov, Michael

AU - Nielsen, Thomas E

N1 - © 2012 American Chemical Society

PY - 2012

Y1 - 2012

N2 - An application of readily available hydrazides in the Petasis 3-component coupling reaction is presented. An investigation of the substrate scope was performed to establish a general, synthetically useful protocol for the formation of hydrazido alcohols, which were selectively converted to oxazolidinone and oxadiazolone ring systems through triphosgene-mediated cyclization reactions.

AB - An application of readily available hydrazides in the Petasis 3-component coupling reaction is presented. An investigation of the substrate scope was performed to establish a general, synthetically useful protocol for the formation of hydrazido alcohols, which were selectively converted to oxazolidinone and oxadiazolone ring systems through triphosgene-mediated cyclization reactions.

KW - Aldehydes

KW - Cyclization

KW - Hydrazines

KW - Molecular Structure

KW - Oxazolidinones

U2 - 10.1021/ol203280b

DO - 10.1021/ol203280b

M3 - Journal article

C2 - 22233295

VL - 14

SP - 640

EP - 643

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 2

ER -

ID: 38230287