Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis. / Geisenberger, O; Givskov, M; Riedel, K; Høiby, N; Tümmler, B; Eberl, Leo.

In: F E M S Microbiology Letters, Vol. 184, No. 2, 2000, p. 273-8.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Geisenberger, O, Givskov, M, Riedel, K, Høiby, N, Tümmler, B & Eberl, L 2000, 'Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis', F E M S Microbiology Letters, vol. 184, no. 2, pp. 273-8.

APA

Geisenberger, O., Givskov, M., Riedel, K., Høiby, N., Tümmler, B., & Eberl, L. (2000). Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis. F E M S Microbiology Letters, 184(2), 273-8.

Vancouver

Geisenberger O, Givskov M, Riedel K, Høiby N, Tümmler B, Eberl L. Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis. F E M S Microbiology Letters. 2000;184(2):273-8.

Author

Geisenberger, O ; Givskov, M ; Riedel, K ; Høiby, N ; Tümmler, B ; Eberl, Leo. / Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis. In: F E M S Microbiology Letters. 2000 ; Vol. 184, No. 2. pp. 273-8.

Bibtex

@article{acf044997a894b2f8d137d051ad76ffc,
title = "Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis",
abstract = "The N-acyl-L-homoserine lactones (AHLs) produced by sequential Pseudomonas aeruginosa isolates from chronically infected patients with cystic fibrosis were analyzed by thin-layer chromatography. It is demonstrated that both the amounts and the types of molecules synthesized by isolates from patients who were monitored over periods of up to 11 years do not change significantly during chronic colonization. However, in the case of a patient who became co-infected with an AHL-producing Burkholderia cepacia strain a dramatic reduction in the amounts of AHLs produced by the co-residing P. aeruginosa isolates was observed.",
keywords = "4-Butyrolactone, Burkholderia Infections, Burkholderia cepacia, Chromatography, Thin Layer, Chronic Disease, Cystic Fibrosis, Gene Expression Regulation, Bacterial, Humans, Lung Diseases, Pseudomonas Infections, Pseudomonas aeruginosa, Signal Transduction",
author = "O Geisenberger and M Givskov and K Riedel and N H{\o}iby and B T{\"u}mmler and Leo Eberl",
year = "2000",
language = "English",
volume = "184",
pages = "273--8",
journal = "F E M S Microbiology Letters",
issn = "0378-1097",
publisher = "Oxford University Press",
number = "2",

}

RIS

TY - JOUR

T1 - Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis

AU - Geisenberger, O

AU - Givskov, M

AU - Riedel, K

AU - Høiby, N

AU - Tümmler, B

AU - Eberl, Leo

PY - 2000

Y1 - 2000

N2 - The N-acyl-L-homoserine lactones (AHLs) produced by sequential Pseudomonas aeruginosa isolates from chronically infected patients with cystic fibrosis were analyzed by thin-layer chromatography. It is demonstrated that both the amounts and the types of molecules synthesized by isolates from patients who were monitored over periods of up to 11 years do not change significantly during chronic colonization. However, in the case of a patient who became co-infected with an AHL-producing Burkholderia cepacia strain a dramatic reduction in the amounts of AHLs produced by the co-residing P. aeruginosa isolates was observed.

AB - The N-acyl-L-homoserine lactones (AHLs) produced by sequential Pseudomonas aeruginosa isolates from chronically infected patients with cystic fibrosis were analyzed by thin-layer chromatography. It is demonstrated that both the amounts and the types of molecules synthesized by isolates from patients who were monitored over periods of up to 11 years do not change significantly during chronic colonization. However, in the case of a patient who became co-infected with an AHL-producing Burkholderia cepacia strain a dramatic reduction in the amounts of AHLs produced by the co-residing P. aeruginosa isolates was observed.

KW - 4-Butyrolactone

KW - Burkholderia Infections

KW - Burkholderia cepacia

KW - Chromatography, Thin Layer

KW - Chronic Disease

KW - Cystic Fibrosis

KW - Gene Expression Regulation, Bacterial

KW - Humans

KW - Lung Diseases

KW - Pseudomonas Infections

KW - Pseudomonas aeruginosa

KW - Signal Transduction

M3 - Journal article

C2 - 10713433

VL - 184

SP - 273

EP - 278

JO - F E M S Microbiology Letters

JF - F E M S Microbiology Letters

SN - 0378-1097

IS - 2

ER -

ID: 44305765