Michael Givskov

Michael Givskov

Professor

Member of:


    1. 2006
    2. A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms

      Allesen-Holm, M., Barken, K. B., Yang, L., Klausen, M., Webb, J. S., Kjelleberg, S., Molin, S., Givskov, Michael & Tolker-Nielsen, T., 2006, In: Molecular Microbiology. 59, 4, p. 1114-28 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein

      Schreiber, K., Boes, N., Eschbach, M., Jaensch, L., Wehland, J., Bjarnsholt, T., Givskov, Michael, Hentzer, M. & Schobert, M., 2006, In: Journal of Bacteriology. 188, 2, p. 659-68 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Biological Trojan horse: Antigen 43 provides specific bacterial uptake and survival in human neutrophils

      Fexby, S., Bjarnsholt, Thomas, Jensen, Peter Østrup, Roos, V., Høiby, Niels, Givskov, Michael & Klemm, P., 2006, In: Infection and Immunity. 75, 1, p. 30-4 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Expedient total synthesis of pyrrothine natural products and analogs

      Hjelmgaard, T., Givskov, Michael & Nielsen, J., 2006, In: Organic & Biomolecular Chemistry. 5, 2, p. 344-8 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Furanones

      de Nys, R., Givskov, Michael, Kumar, N., Kjelleberg, S. & Steinberg, P. D., 2006, In: Progress in Molecular and Subcellular Biology. 42, p. 55-86 31 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Quorum sensing inhibitors: a bargain of effects

      Rasmussen, T. B. & Givskov, Michael, 2006, In: Microbiology. 152, Pt 4, p. 895-904 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Quorum-sensing inhibitors as anti-pathogenic drugs

      Rasmussen, T. B. & Givskov, Michael, 2006, In: International Journal of Medical Microbiology. 296, 2-3, p. 149-61 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional

      Shrout, J. D., Chopp, D. L., Just, C. L., Hentzer, M., Givskov, Michael & Parsek, M. R., 2006, In: Molecular Microbiology. 62, 5, p. 1264-77 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. 2005
    11. Published

      Erratum: Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis (Infection and Immunity (2005) 73, 4 (2504-2514))

      Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, Aug 2005, In: Infection and Immunity. 73, 8, p. 5290 1 p.

      Research output: Contribution to journalComment/debateResearchpeer-review

    12. Published

      Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Burmølle, Mette, Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, Claus Ernst, Molin, S., Høiby, Niels & Givskov, Michael, Feb 2005, In: Microbiology. 151, Pt 2, p. 373-83 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Enhancer-binding proteins with a forkhead-associated domain and the sigma54 regulon in Myxococcus xanthus fruiting body development

      Jelsbak, L., Givskov, Michael & Kaiser, D., 2005, In: Proceedings of the National Academy of Science of the United States of America. 102, 8, p. 3010-5 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudo-monas aeruginosa infections.

      Bjarnsholt, Thomas, Jensen, P. Ø., Rasmussen, T. B., Christoffersen, L., Calum, Henrik Pierre, Hentzer, M., Hougen, H. P., Rygaard, J., Moser, Claus Ernst, Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: F E M S Microbiology. 151, p. 3873-3880 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections

      Bjarnsholt, T., Jensen, P. Ø., Rasmussen, T. B., Christophersen, L., Calum, H., Hentzer, M., Hougen, H., Rygaard, J., Moser, C., Eberl, L., Høiby, N. & Givskov, Michael, 2005, In: Microbiology. 151, Pt 12, p. 3873-80 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Identity and effects of quorum-sensing inhibitors produced by Penicillium species

      Rasmussen, T. B., Skindersoe, M. E., Bjarnsholt, T., Phipps, R. K., Christensen, K. B., Jensen, Peter Østrup, Andersen, Jens Bo, Koch, B., Larsen, T. O., Hentzer, M., Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: Microbiology. 151, Pt 5, p. 1325-40 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Involvement of bacterial quorum-sensing signals in spoilage of bean sprouts

      Rasch, M., Andersen, Jens Bo, Nielsen, K. F., Flodgaard, L. R., Christensen, Henrik, Givskov, Michael & Gram, L., 2005, In: Applied and Environmental Microbiology. 71, 6, p. 3321-30 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Nonbioluminescent strains of Photobacterium phosphoreum produce the cell-to-cell communication signal N-(3-Hydroxyoctanoyl)homoserine lactone

      Flodgaard, L. R., Dalgaard, P., Andersen, Jens Bo, Nielsen, K. F., Givskov, Michael & Gram, L., 2005, In: Applied and Environmental Microbiology. 71, 4, p. 2113-20 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model

      Bragonzi, A., Worlitzsch, D., Pier, G. B., Timpert, P., Ulrich, M., Hentzer, M., Andersen, Jens Bo, Givskov, Michael, Conese, M. & Doring, G., 2005, In: Journal of Infectious Diseases. 192, 3, p. 410-9 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis

      Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, 2005, In: Infection and Immunity. 73, 4, p. 2504-14 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Quorum sensing inhibition: targeting chemical communication in gram-negative bacteria

      Persson, T., Givskov, Michael & Nielsen, J., 2005, In: Current Medicinal Chemistry. 12, 26, p. 3103-15 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector

      Rasmussen, T. B., Bjarnsholt, T., Skindersoe, M. E., Hentzer, M., Kristoffersen, P., Köte, M., Nielsen, J., Eberl, L. & Givskov, Michael, 2005, In: Journal of Bacteriology. 187, 5, p. 1799-814 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. The LuxR receptor: the sites of interaction with quorum-sensing signals and inhibitors

      Koch, B., Liljefors, T., Persson, T., Nielsen, J., Kjelleberg, S. & Givskov, Michael, 2005, In: Microbiology. 151, Pt 11, p. 3589-602 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Transcriptome analysis of Pseudomonas aeruginosa biofilm development: Anaerobic respiration and iron limitation

      Hentzer, M., Eberl, L. & Givskov, Michael, 2005, In: Biofilms. 2, 1, p. 37-61 25 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. 2004
    26. Published

      Quorum sensing in Gram-negative bacteria

      Wu, H., Song, Z., Høiby, Niels & Givskov, Michael, May 2004, In: Progress in Natural Science. 14, 5, p. 377-387 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. An inhibitor of bacterial quorum sensing reduces mortalities caused by Vibriosis in rainbow trout (Oncorhynchus mykiss, Walbaum)

      Rasch, M., Buch, C., Austin, B., Slierendrecht, W. J., Ekmann, K. S., Larsen, J. L., Johansen, C., Riedel, K., Eberl, L., Givskov, Michael & Gram, L., 2004, In: Systematic and Applied Microbiology. 27, 3, p. 350-9 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Dynamics and spatial distribution of beta-lactamase expression in Pseudomonas aeruginosa biofilms.

      Bagge, N., Hentzer, M., Andersen, Jens Bo, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1168-74 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Effects of quorum-sensing on immunoglobulin G responses in a rat model of chronic lung infection with Pseudomonas aeruginosa

      Wu, H., Song, Z., Givskov, Michael & Høiby, N., 2004, In: Microbes and Infection. 6, 1, p. 34-7 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Phosphorus limitation enhances biofilm formation of the plant pathogen Agrobacterium tumefaciens through the PhoR-PhoB regulatory system

      Danhorn, T., Hentzer, M., Givskov, Michael, Parsek, M. R. & Fuqua, C., 2004, In: Journal of Bacteriology. 186, 14, p. 4492-501 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Presence of acylated homoserine lactones (AHLs) and AHL-producing bacteria in meat and potential role of AHL in spoilage of meat

      Bruhn, J. B., Christensen, A. B., Flodgaard, L. R., Nielsen, K. F., Larsen, T. O., Givskov, Michael & Gram, L., 2004, In: Applied and Environmental Microbiology. 70, 7, p. 4293-302 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production.

      Bagge, N., Schuster, M., Hentzer, M., Ciofu, Oana, Givskov, Michael, Greenberg, E. P. & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1175-87 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Pseudomonas aeruginosa with lasI quorum-sensing deficiency during corneal infection

      Zhu, H., Bandara, R., Conibear, T. C. R., Thuruthyil, S. J., Rice, S. A., Kjelleberg, S., Givskov, Michael & Willcox, M. D. P., 2004, In: Investigative Ophthalmology & Visual Science. 45, 6, p. 1897-903 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1

      Labbate, M., Queck, S. Y., Koh, K. S., Rice, S. A., Givskov, Michael & Kjelleberg, S., 2004, In: Journal of Bacteriology. 186, 3, p. 692-8 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Rational design and synthesis of new quorum-sensing inhibitors derived from acylated homoserine lactones and natural products from garlic

      Persson, T., Hansen, T. H., Rasmussen, T. B., Skindersø, M. E., Givskov, Michael & Nielsen, J., 2004, In: Organic & Biomolecular Chemistry. 3, 2, p. 253-62 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice

      Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Molin, S., Givskov, Michael & Høiby, Niels, 2004, In: Journal of Antimicrobial Chemotherapy. 53, 6, p. 1054-61 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. 2003
    38. Published

      Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors

      Hentzer, M., Wu, H., Andersen, Jens Bo, Riedel, K., Rasmussen, T. B., Bagge, N., Kumar, N., Schembri, M. A., Song, Z., Kristoffersen, P., Manefield, M., Costerton, J. W., Molin, S., Eberl, L., Steinberg, P., Kjelleberg, S., Høiby, Niels & Givskov, Michael, 2003, In: EMBO Journal. 22, 15, p. 3803-15 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Bacterial biofilms: prokaryotic adventures in multicellularity

      Webb, J. S., Givskov, Michael & Kjelleberg, S., 2003, In: Current Opinion in Microbiology. 6, 6, p. 578-85 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Cell death in Pseudomonas aeruginosa biofilm development

      Webb, J. S., Thompson, L. S., James, S., Charlton, T., Tolker-Nielsen, T., Koch, B., Givskov, Michael & Kjelleberg, S., 2003, In: Journal of Bacteriology. 185, 15, p. 4585-92 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Identification and characterization of a GDSL esterase gene located proximal to the swr quorum-sensing system of Serratia liquefaciens MG1

      Riedel, K., Talker-Huiber, D., Givskov, Michael, Schwab, H. & Eberl, L., 2003, In: Applied and Environmental Microbiology. 69, 7, p. 3901-10 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics

      Arevalo-Ferro, C., Hentzer, M., Reil, G., Görg, A., Kjelleberg, S., Givskov, Michael, Riedel, K. & Eberl, L., 2003, In: Environmental Microbiology. 5, 12, p. 1350-69 19 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Influence of food preservation parameters and associated microbiota on production rate, profile and stability of acylated homoserine lactones from food-derived Enterobacteriaceae

      Ravn Flodgaard, L., Christensen, A. B., Molin, S., Givskov, Michael & Gram, L., 2003, In: International Journal of Food Microbiology. 84, 2, p. 145-56 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections

      Hentzer, M. & Givskov, Michael, 2003, In: Journal of Clinical Investigation. 112, 9, p. 1300-7 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Quorum sensing : a novel target for the treatment of biofilm infections

      Hentzer, M., Eberl, L., Nielsen, J. & Givskov, Michael, 2003, In: BioDrugs. 17, 4, p. 241-50 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Quorum-sensing-directed protein expression in Serratia proteamaculans B5a

      Christensen, A. B., Riedel, K., Eberl, L., Flodgaard, L. R., Molin, S., Gram, L. & Givskov, Michael, 2003, In: Microbiology. 149, Pt 2, p. 471-83 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Surface motility in Pseudomonas sp. DSS73 is required for efficient biological containment of the root-pathogenic microfungi Rhizoctonia solani and Pythium ultimum

      Andersen, Jens Bo, Koch, B., Nielsen, T. H., Sørensen, D., Hansen, M., Nybroe, O., Christophersen, C., Sørensen, J., Molin, S. & Givskov, Michael, 2003, In: Microbiology. 149, Pt 1, p. 37-46 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Synthesis of furanone-based natural product analogues with quorum sensing antagonist activity

      Hjelmgaard, T., Persson, T., Rasmussen, T. B., Givskov, Michael & Nielsen, J., 2003, In: Bioorganic & Medicinal Chemistry. 11, 15, p. 3261-71 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. 2002
    50. Published

      Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers

      Olsen, J. A., Severinsen, R., Rasmussen, T. B., Hentzer, M., Givskov, Michael, Nielsen, J. & Nielsen, J., 11 Feb 2002, In: Bioorganic and Medicinal Chemistry Letters. 12, 3, p. 325-328 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. An attractive surface: gram-negative bacterial biofilms

      Schembri, M., Givskov, Michael & Klemm, P., 2002, In: Science Signaling. 2002, 132, p. re6

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Antibiotic and biosurfactant properties of cyclic lipopeptides produced by fluorescent Pseudomonas spp. from the sugar beet rhizosphere

      Nielsen, T. H., Sørensen, D., Tobiasen, C., Andersen, Jens Bo, Christophersen, C., Givskov, Michael & Sørensen, J., 2002, In: Applied and Environmental Microbiology. 68, 7, p. 3416-23 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD.

      Bagge, N., Ciofu, Oana, Hentzer, M., Campbell, J. I. A., Givskov, Michael & Høiby, Niels, 2002, In: Antimicrobial Agents and Chemotherapy. 46, 11, p. 3406-11 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Food spoilage--interactions between food spoilage bacteria

      Gram, L., Ravn, L., Rasch, M., Bruhn, J. B., Christensen, A. B. & Givskov, Michael, 2002, In: International Journal of Food Microbiology. 78, 1-2, p. 79-97 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. Genetic analysis of functions involved in the late stages of biofilm development in Burkholderia cepacia H111

      Huber, B., Riedel, K., Köthe, M., Givskov, Michael, Molin, S. & Eberl, L., 2002, In: Molecular Microbiology. 46, 2, p. 411-26 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. Published

      Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover

      Manefield, M., Rasmussen, T. B., Henzter, M., Andersen, Jens Bo, Steinberg, P., Kjelleberg, S. & Givskov, Michael, 2002, In: Microbiology. 148, Pt 4, p. 1119-27 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. Identification and characterization of an N-acylhomoserine lactone-dependent quorum-sensing system in Pseudomonas putida strain IsoF

      Steidle, A., Allesen-Holm, M., Riedel, K., Berg, G., Givskov, Michael, Molin, S. & Eberl, L., 2002, In: Applied and Environmental Microbiology. 68, 12, p. 6371-82 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound

      Hentzer, M., Riedel, K., Rasmussen, T. B., Heydorn, A., Andersen, Jens Bo, Parsek, M. R., Rice, S. A., Eberl, L., Molin, S., Høiby, Niels, Kjelleberg, S. & Givskov, Michael, 2002, In: Microbiology. 148, Pt 1, p. 87-102 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    59. Lipopeptide production in Pseudomonas sp. strain DSS73 is regulated by components of sugar beet seed exudate via the Gac two-component regulatory system

      Koch, B., Nielsen, T. H., Sørensen, D., Andersen, J. B., Christophersen, C., Molin, S., Givskov, Michael, Sørensen, J. & Nybroe, O., 2002, In: Applied and Environmental Microbiology. 68, 9, p. 4509-16 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    60. Lysophosphatidic acid inhibition of the accumulation of Pseudomonas aeruginosa PAO1 alginate, pyoverdin, elastase and LasA

      Laux, D. C., Corson, J. M., Givskov, Michael, Hentzer, M., Møller, A., Wosencroft, K. A., Olson, J. C., Krogfelt, K. A., Goldberg, J. B. & Cohen, P., 2002, In: Microbiology. 148, Pt 6, p. 1709-23 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    61. Quantitative effects of medium hardness and nutrient availability on the swarming motility of Serratia liquefaciens

      Bees, M. A., Andresén, P., Mosekilde, E. & Givskov, Michael, 2002, In: Bulletin of Mathematical Biology. 64, 3, p. 565-87 22 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    62. Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers

      Olsen, J. A., Severinsen, R. E., Rasmussen, T. B., Hentzer, M., Givskov, Michael & Nielsen, J., 2002, In: Bioorganic & Medicinal Chemistry Letters. 12, 3, p. 325-8 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    63. Published

      Targeting quorum sensing for treatment of chronic bacterial biofilm infections

      Hentzer, M., Givskov, Michael & Parsek, M. R., 2002, In: Laboratory Medicine. 33, 4, p. 295-306 12 p.

      Research output: Contribution to journalReviewResearchpeer-review

    64. The identification of a tetracycline resistance gene tet(M), on a Tn916-like transposon, in the Bacillus cereus group

      Agersø, Y., Jensen, L. B., Givskov, Michael & Roberts, M. C., 2002, In: FEMS Microbiology Letters. 214, 2, p. 251-6 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    65. 2001
    66. Alginate overproduction affects Pseudomonas aeruginosa biofilm structure and function

      Hentzer, M., Teitzel, G. M., Balzer, G. J., Heydorn, A., Molin, S., Givskov, Michael & Parsek, M. R., 2001, In: Journal of Bacteriology. 183, 18, p. 5395-401 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    67. Genetic and chemical tools for investigating signaling processes in biofilms

      Charlton, T., Givskov, Michael, deNys, R., Andersen, Jens Bo, Hentzer, M., Rice, S. & Kjelleberg, S., 2001, In: Methods in Enzymology. 336, p. 108-28 21 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    68. Halogenated furanones from the red alga, Delisea pulchra, inhibit carbapenem antibiotic synthesis and exoenzyme virulence factor production in the phytopathogen Erwinia carotovora

      Manefield, M., Welch, M., Givskov, Michael, Salmond, G. P. & Kjelleberg, S., 2001, In: F E M S Microbiology Letters. 205, 1, p. 131-8 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    69. Methods for detecting acylated homoserine lactones produced by Gram-negative bacteria and their application in studies of AHL-production kinetics

      Ravn, L., Christensen, A. B., Molin, S., Givskov, Michael & Gram, L., 2001, In: Journal of Microbiological Methods. 44, 3, p. 239-51 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    70. Published

      N-acyl homoserinelactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms

      Riedel, K., Mentzer, M., Geisenberger, O., Huber, B., Steidle, A., Wu, H., Høiby, Niels, Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, p. 3249-3262

      Research output: Contribution to journalJournal articleResearchpeer-review

    71. N-acyl-L-homoserine lactone-mediated regulation of the lip secretion system in Serratia liquefaciens MG1

      Riedel, K., Ohnesorg, T., Krogfelt, K. A., Hansen, T. S., Omori, K., Givskov, Michael & Eberl, L., 2001, In: Journal of Bacteriology. 183, 5, p. 1805-9 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    72. Published

      N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms

      Riedel, K., Hentzer, M., Geisenberger, O., Huber, B., Steidle, A., Wu, H., Høiby, Niels, Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, Pt 12, p. 3249-62 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    73. Published

      Pseudomonas aeruginosa mutations in lasI and rhlI quorum sensing systems result in milder chronic lung infection

      Wu, H., Song, Z., Givskov, Michael, Doring, G., Worlitzsch, D., Mathee, K., Rygaard, J. & Høiby, Niels, 2001, In: Microbiology. 147, Pt 5, p. 1105-1113 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    74. The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility

      Huber, B., Riedel, K., Hentzer, M., Heydorn, A., Gotschlich, A., Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, Pt 9, p. 2517-28 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    75. Visualization of N-acylhomoserine lactone-mediated cell-cell communication between bacteria colonizing the tomato rhizosphere

      Steidle, A., Sigl, K., Schuhegger, R., Ihring, A., Schmid, M., Gantner, S., Stoffels, M., Riedel, K., Givskov, Michael, Hartmann, A., Langebartels, C. & Eberl, L., 2001, In: Applied and Environmental Microbiology. 67, 12, p. 5761-70 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    76. gfp-based N-acyl homoserine-lactone sensor systems for detection of bacterial communication

      Andersen, J. B., Heydorn, A., Hentzer, M., Eberl, L., Geisenberger, O., Christensen, B. B., Molin, S. & Givskov, Michael, 2001, In: Applied and Environmental Microbiology. 67, 2, p. 575-85 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    77. 2000
    78. A novel and sensitive method for the quantification of N-3-oxoacyl homoserine lactones using gas chromatography-mass spectrometry: application to a model bacterial biofilm

      Charlton, T. S., de Nys, R., Netting, A., Kumar, N., Hentzer, M., Givskov, Michael & Kjelleberg, S., 2000, In: Environmental Microbiology. 2, 5, p. 530-41 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    79. Published

      Detection of N-acyl-homoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa

      Wu, H., Song, Z., Hentzer, M., Andersen, J. B., Heydorn, A., Mathee, K., Moser, C., Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146, p. 2481-2493

      Research output: Contribution to journalJournal articleResearchpeer-review

    80. Published

      Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa

      Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Heydorn, A., Mathee, K., Moser, Claus Ernst, Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146 ( Pt 10), p. 2481-93 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    81. Experimental reproducibility in flow-chamber biofilms

      Heydorn, A., Ersbøll, B. K., Hentzer, M., Parsek, M. R., Givskov, Michael & Molin, S., 2000, In: Microbiology. 146 ( Pt 10), p. 2409-15 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    82. Published

      How Delisea pulchra furanones affect quorum sensing and swarming motility in Serratia liquefaciens MG1

      Rasmussen, T. B., Manefield, M., Andersen, Jens Bo, Eberl, L., Anthoni, U., Christophersen, C., Steinberg, P., Kjelleberg, S. & Givskov, Michael, 2000, In: Microbiology. 146 Pt 12, p. 3237-44 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    83. Inactivation of gltB abolishes expression of the assimilatory nitrate reductase gene (nasB) in Pseudomonas putida KT2442

      Eberl, L., Ammendola, A., Rothballer, M. H., Givskov, Michael, Sternberg, C., Kilstrup, M., Schleifer, K. H. & Molin, S., 2000, In: Journal of Bacteriology. 182, 12, p. 3368-76 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    84. Published

      Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis

      Geisenberger, O., Givskov, Michael, Riedel, K., Høiby, Niels, Tümmler, B. & Eberl, L., 2000, In: F E M S Microbiology Letters. 184, 2, p. 273-8 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    85. Published

      Production of N-acyl-L-homoserine lactones by Pseudomonas aeruginosa isolates from chronic lung infections associated with cystic fibrosis

      Geisenberger, O., Givskov, Michael, Riedel, K., Høiby, Niels, Tümmler, B. & Eberl, L., 2000, In: FEMS Microbiology Letters. 184, p. 273-278

      Research output: Contribution to journalJournal articleResearchpeer-review

    86. Quantification of biofilm structures by the novel computer program COMSTAT

      Heydorn, A., Nielsen, A. T., Hentzer, M., Sternberg, C., Givskov, Michael, Ersbøll, B. K. & Molin, S., 2000, In: Microbiology. 146 ( Pt 10), p. 2395-407 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    87. The interaction of thin-film flow, bacterial swarming and cell differentiation in colonies of Serratia liquefaciens

      Bees, M. A., Andresén, P., Mosekilde, E. & Givskov, Michael, 2000, In: Journal of Mathematical Biology. 40, 1, p. 27-63 37 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    88. rpoS gene function is a disadvantage for Escherichia coli BJ4 during competitive colonization of the mouse large intestine

      Krogfelt, K. A., Hjulgaard, M., Sørensen, K., Cohen, P. & Givskov, Michael, 2000, In: Infection and Immunity. 68, 5, p. 2518-24 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    89. 1999
    90. Application of molecular tools for in situ monitoring of bacterial growth activity

      Molin, S. & Givskov, Michael, 1999, In: Environmental Microbiology. 1, 5, p. 383-91 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    91. Bacterial signals and antagonists: the interaction between bacteria and higher organisms

      Rice, S. A., Givskov, Michael, Steinberg, P. & Kjelleberg, S., 1999, In: Journal of Molecular Microbiology and Biotechnology. 1, 1, p. 23-31 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    92. Distribution of bacterial growth activity in flow-chamber biofilms

      Sternberg, C., Christensen, B. B., Johansen, T., Toftgaard Nielsen, A., Andersen, J. B., Givskov, Michael & Molin, S., 1999, In: Applied and Environmental Microbiology. 65, 9, p. 4108-17 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    93. Evidence that halogenated furanones from Delisea pulchra inhibit acylated homoserine lactone (AHL)-mediated gene expression by displacing the AHL signal from its receptor protein

      Manefield, M., de Nys, R., Kumar, N., Read, R., Givskov, Michael, Steinberg, P. & Kjelleberg, S., 1999, In: Microbiology. 145 ( Pt 2), p. 283-91 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    94. Molecular characterization of the pH-inducible and growth phase-dependent promoter P170 of Lactococcus lactis

      Madsen, S. M., Arnau, J., Vrang, A., Givskov, Michael & Israelsen, H., 1999, In: Molecular Microbiology. 32, 1, p. 75-87 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    95. Molecular tools for study of biofilm physiology

      Christensen, B. B., Sternberg, C., Andersen, J. B., Palmer, R. J., Nielsen, A. T., Givskov, Michael & Molin, S., 1999, In: Methods in Enzymology. 310, p. 20-42 23 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    96. Published

      Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.

      Mathee, K., Ciofu, Oana, Sternberg, C., Lindum, P. W., Campbell, J. I., Jensen, P., Johnsen, A. H., Givskov, Michael, Ohman, D. E., Molin, S., Høiby, Niels & Kharazmi, A., 1999, In: Microbiology. 145 ( Pt 6), p. 1349-57 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    97. Production of acylated homoserine lactones by psychrotrophic members of the Enterobacteriaceae isolated from foods

      Gram, L., Christensen, A. B., Ravn, L., Molin, S. & Givskov, Michael, 1999, In: Applied and Environmental Microbiology. 65, 8, p. 3458-63 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    98. Published

      Quorum sensing systems contribute to the severity of the lung infection of pseudomonas aeruginosa in rats

      Wu, H., Song, Z. J., Givskov, Michael, Mathee, K., Rygaard, J. & Høiby, Niels, 1999, In: Pediatric Pulmonology. Suppl 19, p. 269-269

      Research output: Contribution to journalJournal articleResearchpeer-review

    99. Quorum-sensing cross talk: isolation and chemical characterization of cyclic dipeptides from Pseudomonas aeruginosa and other gram-negative bacteria

      Holden, M. T., Ram Chhabra, S., de Nys, R., Stead, P., Bainton, N. J., Hill, P. J., Manefield, M., Kumar, N., Labatte, M., England, D., Rice, S., Givskov, Michael, Salmond, G. P., Stewart, G. S., Bycroft, B. W., Kjelleberg, S. & Williams, P. F., 1999, In: Molecular Microbiology. 33, 6, p. 1254-66 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    100. Surface motility of serratia liquefaciens MG1

      Eberl, L., Molin, S. & Givskov, Michael, 1999, In: Journal of Bacteriology. 181, 6, p. 1703-12 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    101. Published

      The N-acyl-homoserine lactones from Pseudomonas aeruginosa can be monitored by green flourescent protein in vivo

      Wu, H., Song, Z. J., Lindum, P. W., Moser, C., Givskov, Michael & Høiby, Niels, 1999, In: Netherlands Journal of Medicine. 54, p. 42-42

      Research output: Contribution to journalJournal articleResearchpeer-review

    102. 1998
    103. Published

      Chemical mediation of bacterial surface colonisation by secondary metabolites from the red alga Delisea pulchra

      Maximilian, R., De Nys, R., Holmström, C., Gram, L., Givskov, Michael, Crass, K., Kjelleberg, S. A. & Steinberg, P. D., 1998, In: Aquatic Microbial Ecology. 15, 3, p. 233-246 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    104. Establishment of new genetic traits in a microbial biofilm community

      Christensen, B. B., Sternberg, C., Andersen, J. B., Eberl, L., Moller, S., Givskov, Michael & Molin, S., 1998, In: Applied and Environmental Microbiology. 64, 6, p. 2247-55 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    105. In situ gene expression in mixed-culture biofilms: evidence of metabolic interactions between community members

      Møller, S., Sternberg, C., Andersen, J. B., Christensen, B. B., Ramos, J. L., Givskov, Michael & Molin, S., 1998, In: Applied and Environmental Microbiology. 64, 2, p. 721-32 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    106. Published

      N-Acyl-L-homoserine lactone autoinducers control production of an extracellular lipopeptide biosurfactant required for swarming motility of Serratia liquefaciens MG1

      Lindum, P. W., Anthoni, U., Christophersen, C., Eberl, L., Molin, S. & Givskov, Michael, 1998, In: Journal of Bacteriology. 180, 23, p. 6384-8 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    107. New unstable variants of green fluorescent protein for studies of transient gene expression in bacteria

      Andersen, J. B., Sternberg, C., Poulsen, L. K., Bjorn, S. P., Givskov, Michael & Molin, S., 1998, In: Applied and Environmental Microbiology. 64, 6, p. 2240-6 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    108. Serratia liquefaciens swarm cells exhibit enhanced resistance to predation by Tetrahymena sp

      Ammendola, A., Geisenberger, O., Andersen, J. B., Givskov, Michael, Schleifer, K. H. & Eberl, L., 1998, In: F E M S Microbiology Letters. 164, 1, p. 69-75 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    109. Two separate regulatory systems participate in control of swarming motility of Serratia liquefaciens MG1

      Givskov, Michael, Ostling, J., Eberl, L., Lindum, P. W., Christensen, A. B., Christiansen, G., Molin, S. & Kjelleberg, S., 1998, In: Journal of Bacteriology. 180, 3, p. 742-5 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 5838523