Michael Givskov

Michael Givskov

Professor

Member of:


    1. 2008
    2. Published

      The Pseudomonas aeruginosa autoinducer dodecanoyl-homoserine lactone inhibits the putrescine synthesis in human cells

      Kristiansen, S., Bjarnsholt, Thomas, Adeltoft, D., Ifversen, P. & Givskov, Michael, 2008, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 116, 5, p. 361-371 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Thermal injury induces impaired function in polymorphonuclear neutrophil granulocytes and reduced control of burn wound infection

      Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Christoffersen, L., Damlund, D. S. M., Alhede, M., Bjarnsholt, Thomas, Hougen, H. P., Givskov, Michael, Jacobsen, G. K. & Høiby, Niels, 2008, In: Clinical and Experimental Immunology. 156, 1, p. 102-110 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Why chronic wounds will not heal: a novel hypothesis

      Bjarnsholt, Thomas, Kirketerp-Møller, K., Jensen, Peter Østrup, Madsen, K. G., Phipps, R. K., Krogfelt, K., Høiby, Niels & Givskov, Michael, 2008, In: Wound Repair and Regeneration. 16, 1, p. 2-10 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. 2007
    6. Published

      Microbiological aspects of phyllosoma rearing of the ornate rock lobster Panulirus ornatus

      Bourne, D., Høj, L., Webster, N., Payne, M., Skindersøe, M., Givskov, Michael & Hall, M., 22 Aug 2007, In: Aquaculture. 268, 1-4 SPEC. ISS., p. 274-287 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cftr(-/-) mice

      Hoffmann, N., Lee, B., Hentzer, M., Rasmussen, T. B., Song, Z., Johansen, H. K., Givskov, Michael & Høiby, N., 2007, In: Antimicrobial Agents and Chemotherapy. 51, 10, p. 3677-87 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Effects of iron on DNA release and biofilm development by Pseudomonas aeruginosa

      Yang, L., Barken, K. B., Skindersoe, M. E., Christensen, A. B., Givskov, Michael & Tolker-Nielsen, T., 2007, In: Microbiology. 153, Pt 5, p. 1318-28 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.

      Høiby, Niels, Johansen, Helle Krogh, Ciofu, Oana, Jensen, Peter Østrup, Bjarnsholt, Thomas & Givskov, Michael, 2007, In: Ugeskrift for læger. 169, 48, p. 4163-6 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model

      Hultqvist, Louise Dahl, Moser, C., Jensen, Peter Østrup, Rasmussen, T. B., Christophersen, L., Kjelleberg, S., Kumar, N., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2007, In: Microbiology. 153, Pt 7, p. 2312-20 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Profiling acylated homoserine lactones in Yersinia ruckeri and influence of exogenous acyl homoserine lactones and known quorum-sensing inhibitors on protease production

      Kastbjerg, V. G., Nielsen, K. F., Dalsgaard, I., Rasch, M., Bruhn, J. B., Givskov, Michael & Gram, L., 2007, In: Journal of Applied Microbiology. 102, 2, p. 363-74 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Quorum sensing antagonism from marine organisms

      Skindersoe, M. E., Ettinger-Epstein, P., Rasmussen, T. B., Bjarnsholt, T., de Nys, R. & Givskov, Michael, 2007, In: Marine Biotechnology. 10, 1, p. 56-63 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Quorum sensing antagonism from marine organisms

      Skindersoe, M. E., Ettinger-Epstein, P., Rasmussen, T. B., Bjarnsholt, Thomas, de Nys, R. & Givskov, Michael, 2007, In: Marine Biotechnology. 10, 1, p. 56-63 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Quorum sensing in Serratia

      Van Houdt, R., Givskov, Michael & Michiels, C. W., 2007, In: FEMS Microbiology Reviews. 31, 4, p. 407-24 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Quorum sensing signals are produced by Aeromonas salmonicida and quorum sensing inhibitors can reduce production of a potential virulence factor

      Rasch, M., Kastbjerg, V. G., Bruhn, J. B., Dalsgaard, I., Givskov, Michael & Gram, L., 2007, In: Diseases of Aquatic Organisms. 78, 2, p. 105-13 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens

      Bjarnsholt, T. & Givskov, Michael, 2007, In: Philosophical Transactions of the Royal Society of London. Biological Sciences. 362, 1483, p. 1213-22 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Quorum-sensing regulation of adhesion in Serratia marcescens MG1 is surface dependent

      Labbate, M., Zhu, H., Thung, L., Bandara, R., Larsen, M. R., Willcox, M. D. P., Givskov, Michael, Rice, S. A. & Kjelleberg, S., 2007, In: Journal of Bacteriology. 189, 7, p. 2702-11 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa

      Jensen, Peter Østrup, Bjarnsholt, Thomas, Phipps, R., Rasmussen, T. B., Calum, H., Christoffersen, L., Moser, C., Williams, P., Pressler, T., Givskov, Michael & Høiby, Niels, 2007, In: Microbiology. 153, Pt 5, p. 1329-38 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Silver against Pseudomonas aeruginosa biofilms

      Bjarnsholt, Thomas, Kirketerp-Møller, K., Kristiansen, S., Phipps, R., Nielsen, A. K., Jensen, Peter Østrup, Høiby, Niels & Givskov, Michael, 2007, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 115, 8, p. 921-8 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Well-known quorum sensing inhibitors do not affect bacterial quorum sensing-regulated bean sprout spoilage

      Rasch, M., Rasmussen, T. B., Andersen, J. B., Persson, T., Nielsen, J., Givskov, Michael & Gram, L., 2007, In: Journal of Applied Microbiology. 102, 3, p. 826-37 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. 2006
    22. A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms

      Allesen-Holm, M., Barken, K. B., Yang, L., Klausen, M., Webb, J. S., Kjelleberg, S., Molin, S., Givskov, Michael & Tolker-Nielsen, T., 2006, In: Molecular Microbiology. 59, 4, p. 1114-28 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein

      Schreiber, K., Boes, N., Eschbach, M., Jaensch, L., Wehland, J., Bjarnsholt, T., Givskov, Michael, Hentzer, M. & Schobert, M., 2006, In: Journal of Bacteriology. 188, 2, p. 659-68 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Biological Trojan horse: Antigen 43 provides specific bacterial uptake and survival in human neutrophils

      Fexby, S., Bjarnsholt, Thomas, Jensen, Peter Østrup, Roos, V., Høiby, Niels, Givskov, Michael & Klemm, P., 2006, In: Infection and Immunity. 75, 1, p. 30-4 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Expedient total synthesis of pyrrothine natural products and analogs

      Hjelmgaard, T., Givskov, Michael & Nielsen, J., 2006, In: Organic & Biomolecular Chemistry. 5, 2, p. 344-8 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Furanones

      de Nys, R., Givskov, Michael, Kumar, N., Kjelleberg, S. & Steinberg, P. D., 2006, In: Progress in Molecular and Subcellular Biology. 42, p. 55-86 31 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Quorum sensing inhibitors: a bargain of effects

      Rasmussen, T. B. & Givskov, Michael, 2006, In: Microbiology. 152, Pt 4, p. 895-904 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Quorum-sensing inhibitors as anti-pathogenic drugs

      Rasmussen, T. B. & Givskov, Michael, 2006, In: International Journal of Medical Microbiology. 296, 2-3, p. 149-61 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional

      Shrout, J. D., Chopp, D. L., Just, C. L., Hentzer, M., Givskov, Michael & Parsek, M. R., 2006, In: Molecular Microbiology. 62, 5, p. 1264-77 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. 2005
    31. Published

      Erratum: Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis (Infection and Immunity (2005) 73, 4 (2504-2514))

      Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, Aug 2005, In: Infection and Immunity. 73, 8, p. 5290 1 p.

      Research output: Contribution to journalComment/debateResearchpeer-review

    32. Published

      Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Burmølle, Mette, Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, Claus Ernst, Molin, S., Høiby, Niels & Givskov, Michael, Feb 2005, In: Microbiology. 151, Pt 2, p. 373-83 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Enhancer-binding proteins with a forkhead-associated domain and the sigma54 regulon in Myxococcus xanthus fruiting body development

      Jelsbak, L., Givskov, Michael & Kaiser, D., 2005, In: Proceedings of the National Academy of Science of the United States of America. 102, 8, p. 3010-5 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudo-monas aeruginosa infections.

      Bjarnsholt, Thomas, Jensen, P. Ø., Rasmussen, T. B., Christoffersen, L., Calum, Henrik Pierre, Hentzer, M., Hougen, H. P., Rygaard, J., Moser, Claus Ernst, Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: F E M S Microbiology. 151, p. 3873-3880 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections

      Bjarnsholt, T., Jensen, P. Ø., Rasmussen, T. B., Christophersen, L., Calum, H., Hentzer, M., Hougen, H., Rygaard, J., Moser, C., Eberl, L., Høiby, N. & Givskov, Michael, 2005, In: Microbiology. 151, Pt 12, p. 3873-80 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Identity and effects of quorum-sensing inhibitors produced by Penicillium species

      Rasmussen, T. B., Skindersoe, M. E., Bjarnsholt, T., Phipps, R. K., Christensen, K. B., Jensen, Peter Østrup, Andersen, Jens Bo, Koch, B., Larsen, T. O., Hentzer, M., Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: Microbiology. 151, Pt 5, p. 1325-40 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Involvement of bacterial quorum-sensing signals in spoilage of bean sprouts

      Rasch, M., Andersen, Jens Bo, Nielsen, K. F., Flodgaard, L. R., Christensen, Henrik, Givskov, Michael & Gram, L., 2005, In: Applied and Environmental Microbiology. 71, 6, p. 3321-30 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Nonbioluminescent strains of Photobacterium phosphoreum produce the cell-to-cell communication signal N-(3-Hydroxyoctanoyl)homoserine lactone

      Flodgaard, L. R., Dalgaard, P., Andersen, Jens Bo, Nielsen, K. F., Givskov, Michael & Gram, L., 2005, In: Applied and Environmental Microbiology. 71, 4, p. 2113-20 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model

      Bragonzi, A., Worlitzsch, D., Pier, G. B., Timpert, P., Ulrich, M., Hentzer, M., Andersen, Jens Bo, Givskov, Michael, Conese, M. & Doring, G., 2005, In: Journal of Infectious Diseases. 192, 3, p. 410-9 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis

      Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, 2005, In: Infection and Immunity. 73, 4, p. 2504-14 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Quorum sensing inhibition: targeting chemical communication in gram-negative bacteria

      Persson, T., Givskov, Michael & Nielsen, J., 2005, In: Current Medicinal Chemistry. 12, 26, p. 3103-15 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector

      Rasmussen, T. B., Bjarnsholt, T., Skindersoe, M. E., Hentzer, M., Kristoffersen, P., Köte, M., Nielsen, J., Eberl, L. & Givskov, Michael, 2005, In: Journal of Bacteriology. 187, 5, p. 1799-814 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. The LuxR receptor: the sites of interaction with quorum-sensing signals and inhibitors

      Koch, B., Liljefors, T., Persson, T., Nielsen, J., Kjelleberg, S. & Givskov, Michael, 2005, In: Microbiology. 151, Pt 11, p. 3589-602 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Transcriptome analysis of Pseudomonas aeruginosa biofilm development: Anaerobic respiration and iron limitation

      Hentzer, M., Eberl, L. & Givskov, Michael, 2005, In: Biofilms. 2, 1, p. 37-61 25 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. 2004
    46. Published

      Quorum sensing in Gram-negative bacteria

      Wu, H., Song, Z., Høiby, Niels & Givskov, Michael, May 2004, In: Progress in Natural Science. 14, 5, p. 377-387 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. An inhibitor of bacterial quorum sensing reduces mortalities caused by Vibriosis in rainbow trout (Oncorhynchus mykiss, Walbaum)

      Rasch, M., Buch, C., Austin, B., Slierendrecht, W. J., Ekmann, K. S., Larsen, J. L., Johansen, C., Riedel, K., Eberl, L., Givskov, Michael & Gram, L., 2004, In: Systematic and Applied Microbiology. 27, 3, p. 350-9 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Dynamics and spatial distribution of beta-lactamase expression in Pseudomonas aeruginosa biofilms.

      Bagge, N., Hentzer, M., Andersen, Jens Bo, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1168-74 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Effects of quorum-sensing on immunoglobulin G responses in a rat model of chronic lung infection with Pseudomonas aeruginosa

      Wu, H., Song, Z., Givskov, Michael & Høiby, N., 2004, In: Microbes and Infection. 6, 1, p. 34-7 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Phosphorus limitation enhances biofilm formation of the plant pathogen Agrobacterium tumefaciens through the PhoR-PhoB regulatory system

      Danhorn, T., Hentzer, M., Givskov, Michael, Parsek, M. R. & Fuqua, C., 2004, In: Journal of Bacteriology. 186, 14, p. 4492-501 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Presence of acylated homoserine lactones (AHLs) and AHL-producing bacteria in meat and potential role of AHL in spoilage of meat

      Bruhn, J. B., Christensen, A. B., Flodgaard, L. R., Nielsen, K. F., Larsen, T. O., Givskov, Michael & Gram, L., 2004, In: Applied and Environmental Microbiology. 70, 7, p. 4293-302 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production.

      Bagge, N., Schuster, M., Hentzer, M., Ciofu, Oana, Givskov, Michael, Greenberg, E. P. & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1175-87 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Pseudomonas aeruginosa with lasI quorum-sensing deficiency during corneal infection

      Zhu, H., Bandara, R., Conibear, T. C. R., Thuruthyil, S. J., Rice, S. A., Kjelleberg, S., Givskov, Michael & Willcox, M. D. P., 2004, In: Investigative Ophthalmology & Visual Science. 45, 6, p. 1897-903 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1

      Labbate, M., Queck, S. Y., Koh, K. S., Rice, S. A., Givskov, Michael & Kjelleberg, S., 2004, In: Journal of Bacteriology. 186, 3, p. 692-8 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. Rational design and synthesis of new quorum-sensing inhibitors derived from acylated homoserine lactones and natural products from garlic

      Persson, T., Hansen, T. H., Rasmussen, T. B., Skindersø, M. E., Givskov, Michael & Nielsen, J., 2004, In: Organic & Biomolecular Chemistry. 3, 2, p. 253-62 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 5838523