Niels Høiby
Professor, No job title
Bacteriology
Blegdamsvej 3B, 2200 København N, 24 Bygning 24, Building: 24-1-16
Member of:
- 2024
- Published
In vivo evolution of antimicrobial resistance in a biofilm model of Pseudomonas aeruginosa lung infection
Higazy, Doaa Mohamed Mohamed E, Pham, A. D., van Hasselt, C., Høiby, Niels, Jelsbak, L., Moser, Claus Ernst & Ciofu, Oana, 2024, In: The ISME Journal. 18, 1Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Centennial celebrations of the Danish Pasteur Society
Høiby, Niels & Bjarnsholt, Thomas, 2024, In: APMIS. 132, 1, p. 3Research output: Contribution to journal › Editorial › Research
- Published
Louis Pasteur and the birth of microbiology in Denmark
Høiby, Niels, 2024, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 132, 1, p. 43-52Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Colistin Enhances Rifampicin's Antimicrobial Action in Colistin-Resistant Pseudomonas aeruginosa Biofilms
Armengol, E., Kragh, K. N., Tolker-Nielsen, Tim, Sierra, J. M., Higazy, Doaa Mohamed Mohamed E, Ciofu, Oana, Viñas, M. & Høiby, Niels, 2023, In: Antimicrobial Agents and Chemotherapy. 67, 4, e0164122.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Attainment of Target Antibiotic Levels by Oral Treatment of Left-sided Infective Endocarditis: A POET Substudy
Bock, M., Theut, A. M., van Hasselt, J. G. C., Wang, H., Fuursted, K., Hoiby, N., Lerche, C. J., Ihlemann, N., Gill, S., Christiansen, U., Nielsen, H. L., Lemming, L., Elming, H., Povlsen, J. A., Bruun, N. E., Hofsten, D., Fosbøl, E. L., Kober, L., Schultz, M., Pries-Heje, M. M. & 9 others, , 2023, In: Clinical Infectious Diseases. 77, 2, p. 242–251 10 p., 168.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rifampicin reduces plasma concentration of linezolid in patients with infective endocarditis
Bock, M., Van Hasselt, J. G. C., Schwartz, F., Wang, H., Høiby, N., Fuursted, K., Ihlemann, N., Gill, S., Christiansen, U., Bruun, N. E., Elming, H., Povlsen, J. A., Køber, L., Høfsten, D. E., Fosbøl, E. L., Pries-Heje, M. M., Christensen, J. J., Rosenvinge, F. S., Torp-Pedersen, C., Helweg-Larsen, J. & 4 others, , 2023, In: The Journal of antimicrobial chemotherapy. 78, 12, p. 2840–2848 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperbaric oxygen therapy augments ciprofloxacin effect against Pseudomonas aeruginosa biofilm infected chronic wounds in a mouse model
Laulund, A. S., Schwartz, F. A., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Calum, Henrik Pierre, Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 5, 100100.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperbaric oxygen therapy counteracts Pseudomonas aeruginosa biofilm micro-compartment phenomenon in murine thermal wounds
Laulund, A. S., Schwartz, F. A., Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 6, 8 p., 100159.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Murine burn lesion model for studying acute and chronic wound infections
Calum, Henrik Pierre, Trøstrup, H., Laulund, A. S., Thomsen, K., Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 7, p. 477-490 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Tolerance and resistance of microbial biofilms
Ciofu, Oana, Moser, Claus Ernst, Jensen, Peter Østrup & Høiby, Niels, 2022, In: Nature Reviews Microbiology. 20, p. 621–635Research output: Contribution to journal › Review › Research › peer-review
- Published
Hyperbaric Oxygen Treatment May Advance the Outcome of Antibiotic Treatment of Biofilm Infections
Jensen, Peter Østrup, Møller, S. A., Stjernekilde, S., Olsen, P., Moser, Claus Ernst, Schwartz, F. A., Lerche, C. J., Høiby, Niels, Hyldegaard, Ole, Faurholt-jepsen, D. & Kolpen, Mette, 2022, Antibiofilm Strategies: Current and Future Applications to Prevent, Control and Eradicate Biofilms. Springer, p. 201-223 (Antibiofilm Strategies, Vol. 11).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Lactoferricin-inspired peptide AMC-109 augments the effect of ciprofloxacin against Pseudomonas aeruginosa biofilm in chronic murine wounds
Laulund, A. S., Schwartz, F. A., Christophersen, L., Høiby, Niels, Svendsen, J. S. M., Stensen, W., Thomsen, K., Cavanagh, J. P. & Moser, Claus Ernst, 2022, In: Journal of Global Antimicrobial Resistance. 29, p. 185-193 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis
Lerche, C. J., Schwartz, F., Pries-Heje, M. M., Fosbøl, E. L., Iversen, Kasper, Jensen, Peter Østrup, Høiby, Niels, Hyldegaard, Ole, Bundgård, Henning & Moser, Claus Ernst, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 805964.Research output: Contribution to journal › Review › Research › peer-review
- Published
Adaptive Immune Response to Mycobacterium abscessus Complex (MABSC) in Cystic Fibrosis and the Implications of Cross-Reactivity
Mauch, R. M., Jensen, Peter Østrup, Qvist, T., Kolpen, M., Moser, Claus Ernst, Pressler, T., Nolasco da Silva, M. T., Høiby, Niels & Copenhagen Study Group on Mycobacterial Infections in Cystic Fibrosis, C. S. G. O. M. I. I. C. F., 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 858398.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chicken IgY reduces the risk of Pseudomonas aeruginosa urinary tract infections in a murine model
Schwartz, F. A., Christophersen, L., Thomsen, K., Baekdal, S., Pals Bendixen, M., Jørgensen, M., Bull Rasmussen, I. K., Laulund, A. S., Høiby, Niels & Moser, Claus Ernst, 2022, In: Frontiers in Microbiology. 13, 988386.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamics of a Staphylococcus aureus infective endocarditis simulation model
Schwartz, F. A., Nielsen, L., Struve Andersen, J., Bock, M., Christophersen, L., Sunnerhagen, T., Lerche, C. J., Bay, Lene, Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 8, p. 515-523Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment
Thomsen, K., Kobayashi, O., Kishi, K., Shirai, R., Jensen, Peter Østrup, Heydorn, A., Hentzer, M., Calum, Henrik Pierre, Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 7, p. 458-476Research output: Contribution to journal › Review › Research › peer-review
- Published
Immune Response to Biofilm Growing Pulmonary Pseudomonas aeruginosa Infection
Thomsen, K., Høiby, Niels, Jensen, Peter Østrup, Ciofu, Oana & Moser, Claus Ernst, 2022, In: Biomedicines. 10, 9, 2064.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of antibiotic treatment and phagocyte infiltration on development of Pseudomonas aeruginosa biofilm—Insights from the application of a novel PF hydrogel model in vitro and in vivo
Wu, H., Song, L., Yam, J. K. H., Plotkin, M., Wang, H., Rybtke, Morten Levin, Seliktar, D., Kofidis, T., Høiby, Niels, Tolker-Nielsen, Tim, Song, Z. & Givskov, Michael, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 826450.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combination and nanotechnology based pharmaceutical strategies for combating respiratory bacterial biofilm infections
Zhang, L., Bera, H., Wang, H., Wang, J., Guo, Y., Shi, C., Cun, D., Moser, Claus Ernst, Høiby, Niels & Yang, Mingshi, 2022, In: International Journal of Pharmaceutics. 616, 121507.Research output: Contribution to journal › Review › Research › peer-review
- 2021
- Published
Autologous fibrin sealant co-delivered with antibiotics is a robust method for topical antibiotic treatment after sinus surgery
Aanæs, Kasper, Nielsen, Kim G., Arndal, E., von Buchwald, Christian, Pressler, T. & Høiby, Niels, 1 Feb 2021, In: Acta Oto-Laryngologica. 141, 2, p. 181-186 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maintaining normal lung function in children with cystic fibrosis is possible with aggressive treatment regardless of Pseudomonas aeruginosa infections
Hansen, C. R., Gilljam, M., Olesen, H. V., Høiby, Niels, Karpati, F., Johansson, E., Krantz, C., Skov, M., Pressler, T. & Lindblad, A., 2021, In: Acta Pædiatrica. 110, 9, p. 2607-2609 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adjunctive S100A8/A9 Immunomodulation Hinders Ciprofloxacin Resistance in Pseudomonas aeruginosa in a Murine Biofilm Wound Model
Laulund, A. S., Schwartz, F., Trøstrup, H., Thomsen, K., Christophersen, L., Calum, Henrik Pierre, Ciofu, Oana, Høiby, Niels & Moser, Claus Ernst, 2021, In: Frontiers in Cellular and Infection Microbiology. 11, 652012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-biofilm Approach in Infective Endocarditis Exposes New Treatment Strategies for Improved Outcome
Lerche, C. J., Schwartz, F., Theut, M., Fosbøl, E. L., Iversen, Kasper, Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2021, In: Frontiers in Cell and Developmental Biology. 9, 25 p., 643335.Research output: Contribution to journal › Review › Research › peer-review
- Published
SARS-CoV-2 infection dynamics in Denmark, February through October 2020: Nature of the past epidemic and how it may develop in the future
Rasmussen, S., Petersen, M. S. & Høiby, Niels, 2021, In: PLoS ONE. 16, 4 April, e0249733.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct contribution of hyperbaric oxygen therapy to human neutrophil function and antibiotic efficacy against Staphylococcus aureus
Schwartz, F. A., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Laulund, A. S., Woetmann, Anders , Høiby, Niels & Moser, Claus Ernst, 2021, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 129, 9, p. 566-573Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel human in vitro vegetation simulation model for infective endocarditis
Schwartz, F. A., Christophersen, L., Laulund, A. S., Lundquist, R., Lerche, C., Rude Nielsen, P., Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2021, In: APMIS. 129, 11, p. 653-662 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Azithromycin potentiates avian IgY effect against Pseudomonas aeruginosa in a murine pulmonary infection model
Thomsen, K., Christophersen, L., Lerche, C. J., Holmgaard, D. B., Calum, Henrik Pierre, Høiby, Niels & Moser, Claus Ernst, 2021, In: International Journal of Antimicrobial Agents. 57, 1, 106213.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
The evolutionary trajectories of P. aeruginosa in biofilm and planktonic growth modes exposed to ciprofloxacin: beyond selection of antibiotic resistance
Ahmed, M. N., Abdelsamad, A., Wassermann, T., Porse, A., Becker, J., Sommer, M. O. A., Høiby, Niels & Ciofu, Oana, 2020, In: npj Biofilms and Microbiomes. 6, 1, 10 p., 28.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs
Arndal, E., Johansen, Helle Krogh, Haagensen, J. A. J., Bartell, J. A., Marvig, R. L., Alanin, M., Aanæs, Kasper, Høiby, Niels, Nielsen, Kim G., Backer, Vibeke & von Buchwald, Christian, 2020, In: The European Respiratory Journal. 55, 1, 4 p., 1901472.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology
Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo demonstration of Pseudomonas aeruginosa biofilms as independent pharmacological microcompartments
Christophersen, L., Schwartz, F. A., Lerche, C. J., Svanekjær, T., Kragh, K. N., Laulund, A. S., Thomsen, K., Henneberg, K. Å., Sams, T., Høiby, Niels & Moser, Claus Ernst, 2020, In: Journal of Cystic Fibrosis. 19, 6, p. 996-1003Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Further Commentary
Hengzhuang, W. & Høiby, Niels, 2020, In: Pediatric Pulmonology. 55, 1, 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation
Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibody response against Pseudomonas aeruginosa and its relationship with immune mediators in the upper and lower airways of cystic fibrosis patients
Mauch, R. M., Hentschel, J., Aanæs, Kasper, Barucha, A., Nolasco da Silva, M. T., Levy, C. E., Høiby, Niels & Mainz, J. G., 2020, In: Pediatric Pulmonology. 55, 4, p. 959-967Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa antibody response in cystic fibrosis decreases rapidly following lung transplantation
Schwensen, H. F., Moser, Claus Ernst, Perch, Michael, Pressler, T. & Høiby, Niels, 2020, In: Journal of Cystic Fibrosis. 19, 4, p. 587-594Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Lack of the Major Multifunctional Catalase KatA in Pseudomonas aeruginosa Accelerates Evolution of Antibiotic Resistance in Ciprofloxacin-Treated Biofilms
Ahmed, M. N., Porse, A., Abdelsamad, A., Sommer, M., Høiby, Niels & Ciofu, Oana, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 10, 12 p., e00766-19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimization of colistin dosing regimen for cystic fibrosis patients with chronic Pseudomonas aeruginosa biofilm lung infections
Hengzhuang, W., Green, K., Pressler, T., Skov, M., Katzenstein, T. L., Wu, X. & Høiby, Niels, 2019, In: Pediatric Pulmonology. 54, 5, p. 575-580Research output: Contribution to journal › Journal article › Research › peer-review
- Published
P. aeruginosa flow-cell biofilms are enhanced by repeated phage treatments but can be eradicated by phage-ciprofloxacin combination: —monitoring the phage–P. aeruginosa biofilms interactions
Henriksen, K., Rørbo, N., Rybtke, Morten Levin, Martinet, M. G., Tolker-Nielsen, Tim, Høiby, Niels, Middelboe, Mathias & Ciofu, Oana, 2019, In: Pathogens and Disease. 77, 2, 11 p., ftz011.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth
Høiby, Niels, Henneberg, K. Å., Wang, H., Stavnsbjerg, Camilla, Bjarnsholt, Thomas, Ciofu, Oana, Johansen, U. R. & Sams, T., 2019, In: International Journal of Antimicrobial Agents. 53, 5, p. 564-573Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air
Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-Jepsen, Daniel, Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis
Lerche, C. J., Christophersen, L. J., Goetze, J. P., Nielsen, P. R., Thomsen, K., Enevold, C., Høiby, Niels, Jensen, Peter Østrup, Bundgård, Henning & Moser, Claus Ernst, 2019, In: PLoS ONE. 14, 4, 16 p., e0215333.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretory IgA-mediated immune response in saliva and early detection of Pseudomonas aeruginosa in the lower airways of pediatric cystic fibrosis patients
Mauch, R. M., Rossi, C. L., Nolasco da Silva, M. T., Bianchi Aiello, T., Ribeiro, J. D., Ribeiro, A. F., Høiby, Niels & Levy, C. E., 2019, In: Medical Microbiology and Immunology. 208, 2, p. 205-213 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients
Molchanova, N., Wang, H., Hansen, Paul Robert, Høiby, Niels, Nielsen, Hanne Mørck & Franzyk, Henrik, 2019, In: Frontiers in Microbiology. 10, 9 p., 275.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic therapy as personalized medicine - general considerations and complicating factors
Moser, Claus Ernst, Lerche, C. J., Thomsen, K., Hartvig, T., Schierbeck, J., Jensen, Peter Østrup, Ciofu, Oana & Høiby, Niels, 2019, In: APMIS. 127, 5, p. 361-371Research output: Contribution to journal › Review › Research › peer-review
- Published
Editorial comment
Moser, Claus Ernst, Song, Z. & Høiby, Niels, 2019, In: APMIS. 127, 5, 1 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients
Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibody response against Mycobacterium avium complex in cystic fibrosis patients measured by a novel IgG ELISA test
Ravnholt, C., Qvist, T., Kolpen, M., Pressler, T., Skov, M. & Høiby, Niels, 2019, In: Journal of Cystic Fibrosis. 18, 4, p. 516-521Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Evolution of Antibiotic Resistance in Biofilm and Planktonic Pseudomonas aeruginosa Populations Exposed to Subinhibitory Levels of Ciprofloxacin
Ahmed, M. N. A., Porse, A., Sommer, M., Høiby, Niels & Ciofu, Oana, 1 Aug 2018, In: Antimicrobial Agents and Chemotherapy. 62, 8, 12 p., e00320-18.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study
Alanin, M. C., Pressler, T., Aanæs, Kasper, Ekstrøm, Claus Thorn, Skov, M., Johansen, Helle Krogh, Nielsen, Kim G., von Buchwald, Christian & Høiby, Niels, 2018, In: Health Services Research. 1, 8, 5 p., e52.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adaptation of Pseudomonas aeruginosa to the chronic phenotype by mutations in the algTmucABD operon in isolates from Brazilian cystic fibrosis patients
Caçador, N. C., Paulino da Costa Capizzani, C., Monteiro Marin Torres, L. A. G., Galetti, R., Ciofu, Oana, Lúcia da Costa Darini, A. & Høiby, Niels, 2018, In: PLoS ONE. 13, 11, 11 p., e0208013.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms
Gade, P. A. V., Olsen, T. B., Jensen, Peter Østrup, Kolpen, Mette, Høiby, Niels, Henneberg, K. Å. & Sams, T., 2018, In: PLoS ONE. 13, 6, 16 p., e0198909.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IgG avidity to Pseudomonas aeruginosa over the course of chronic lung biofilm infection in cystic fibrosis
Mauch, R. M., Nørregaard, L. L., Ciofu, Oana, Levy, C. E. & Høiby, Niels, 2018, In: Journal of Cystic Fibrosis. 17, 3, p. 356-359Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis
Mauch, R. M., Jensen, Peter Østrup, Moser, Claus Ernst, Levy, C. E. & Høiby, Niels, 2018, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17, 2, p. 143-152Research output: Contribution to journal › Review › Research › peer-review
- Published
Next generation microbiology and cystic fibrosis diagnostics: are we there yet?
Moser, Claus Ernst, Thomsen, T. R. & Høiby, Niels, 2018, In: Current Opinion in Pulmonary Medicine. 24, 6, p. 599-605Research output: Contribution to journal › Review › Research › peer-review
- Published
The importance of early diagnosis of Mycobacterium abscessus complex in patients with cystic fibrosis
Ravnholt, C., Kolpen, M., Skov, M., Moser, C., Katzenstein, T. L., Pressler, T., Høiby, Niels & Qvist, T., 2018, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 126, 12, p. 885-891 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A systematic review of studies on the faecal microbiota in anorexia nervosa: future research may need to include microbiota from the small intestine
Schwensen, H. F., Kan, C., Treasure, J., Høiby, Niels & Sjögren, M., 2018, In: Eating and Weight Disorders. 23, 4, p. 399-418Research output: Contribution to journal › Review › Research › peer-review
- Published
Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor
Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Feb 2018, In: International Wound Journal. 15, 1, p. 123-132Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia
Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, Kim G., Johansen, Helle Krogh & von Buchwald, Christian, Mar 2017, In: International Forum of Allergy Rhinology. 7, 3, p. 240-247Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phenotypic shift in Pseudomonas aeruginosa populations from cystic fibrosis lungs after 2-week antipseudomonal treatment
Fernandez-Barat, L., Ciofu, Oana, Kragh, K. N., Pressler, T., Johansen, U., Motos, A., Torres, A. & Høiby, Niels, Mar 2017, In: Journal of Cystic Fibrosis. 16, 2, p. 222-229Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A short history of microbial biofilms and biofilm infections
Høiby, Niels, Apr 2017, In: APMIS. 125, 4, p. 272-275 4 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Diagnosis of biofilm infections in cystic fibrosis patients
Høiby, Niels, Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup, Kolpen, Mette, Qvist, T., Aanæs, Kasper, Pressler, T., Skov, M. & Ciofu, Oana, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 339-343 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Experimental Pseudomonas aeruginosa mediated rhino sinusitis in mink
Kirkeby, Svend, Hammer, Anne Sofie Vedsted, Høiby, Niels & Salomonsen, C. M., May 2017, In: International Journal of Pediatric Otorhinolaryngology. 96, p. 156-163 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
O-2 AFFECTS THE ACTIVITY OF AMIKACIN ON MYCOBACTERIUM ABSCESSUS BIOFILM
Kolpen, M., Ravnholt, C., Qvist, T., Kragh, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, Sep 2017, In: Pediatric Pulmonology. 52, S47, p. S359-S360 379.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin
Kolpen, Mette, Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperbaric oxygen treatment augments tobramycin efficacy in experimental staphylococcus aureus endocarditis
Lerche, C. J., Christophersen, L. J., Kolpen, Mette, Nielsen, P. R., Trøstrup, H., Thomsen, K., Hyldegaard, Ole, Bundgård, Henning, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Antimicrobial Agents. 50, 3, p. 406-412Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretory IgA response against Pseudomonas aeruginosa in the upper airways and the link with chronic lung infection in cystic fibrosis
Mauch, R. M., Rossi, C. L., Aiello, T. B., Ribeiro, J. D., Ribeiro, A. F., Høiby, Niels & Levy, C. E., 2017, In: Pathogens and Disease. 75, 6, 4 p., ftx069.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilms and host response - helpful or harmful
Moser, Claus Ernst, Pedersen, H. T., Lerche, C. J., Kolpen, Mette, Line, L., Thomsen, K., Høiby, Niels & Jensen, Peter Østrup, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 320-338 19 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Sinus bacteriology in patients with cystic fibrosis or primary ciliary dyskinesia: A systematic review
Møller, M. E., Alanin, M. C., Grønhøj, C., Aanæs, Kasper, Høiby, Niels & von Buchwald, Christian, 2017, In: American Journal of Rhinology and Allergy. 31, 5, p. 293-298 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Evaluation of a bovine antibody test for diagnosing Mycobacterium avium complex in patients with cystic fibrosis
Qvist, T., Pressler, T., Katzenstein, T. L., Høiby, Niels & Collins, M. T., Jan 2017, In: Pediatric Pulmonology. 52, 1, p. 34-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Individual pharmacokinetic variation leads to underdosing of ciprofloxacin in some cystic fibrosis patients
Schultz, A. N. Ø., Høiby, Niels, Nielsen, X. C., Pressler, T., Dalhoff, Kim, Duno, M., Buchard, Anders, Johansen, H. K., Wang, H. & Dalbøge, C. S., Mar 2017, In: Pediatric Pulmonology. 52, 3, p. 319-323 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic urinary tract infections in patients with spinal cord lesions – biofilm infection with need for long-term antibiotic treatment
Tofte, N., Nielsen, A. C. Y., Trøstrup, H., Andersen, C. B., Von Linstow, M., Hansen, B., Biering-Sørensen, Fin, Høiby, Niels & Moser, Claus Ernst, Apr 2017, In: APMIS. 125, 4, p. 385-391 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines—implications for delayed wound closure?
Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Oct 2017, In: Pathogens and Disease. 75, 7, 10 p., ftx068.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds
Trøstrup, H., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Molecular Sciences. 18, 7, 13 p., 1359.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Sinus surgery postpones chronic gram-negative lung infection: Cohort study of 106 patients with cystic fibrosis
Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G., Taylor-Robinson, D., Waldmann, E., Johansen, Helle Krogh & von Buchwald, Christian, 2016, In: Rhinology. 54, 3, p. 206-213 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diffusion retardation by binding of tobramycin in an alginate biofilm model
Cao, B., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Sneppen, Kim, Høiby, Niels, Moser, Claus Ernst & Sams, T., 21 Apr 2016, In: P L o S One. 11, 4, 11 p., e0153616.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of pulmonary and lymph node dendritic cells during chronic Pseudomonas aeruginosa lung infection in mice
Damlund, D. S. M., Christophersen, L., Jensen, Peter Østrup, Alhede, M., Høiby, Niels & Moser, Claus Ernst, Jun 2016, In: APMIS - Journal of Pathology, Microbiology and Immunology. 124, 6, p. 500-507 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kai Adolf Jensen, professor i almindelig patologi
Høiby, Niels, 2016, In: Bibliotek for Laeger. 208, 4, p. 344-361Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions
Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment
Kolpen, Mette, Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Forøget renal udskillelse af antibiotika kan resultere i underdosering ved sepsis
Moser, Claus Ernst, Hartvig, T., Schierbeck, J. & Høiby, Niels, 2016, In: Ugeskrift for Laeger. 178, p. 2-6 5 p., V05150426.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New technology markedly improves hand-hygiene performance among healthcare workers after restroom visits
Møller-Sørensen, H., Korshin, A., Mogensen, T. & Høiby, Niels, Apr 2016, In: Journal of Hospital Infection. 92, 4, p. 337-339 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The dlt genes play a role in antimicrobial tolerance of Streptococcus mutans biofilms
Nilsson, Carl Martin Peter, Rybtke, Morten Levin, Givskov, Michael, Høiby, Niels, Twetman, Svante & Tolker-Nielsen, Tim, Sep 2016, In: International Journal of Antimicrobial Agents. 48, 3, p. 298–304Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome sequence of Pseudomonas aeruginosa strain DK1-NH57388A, a stable mucoid cystic fibrosis isolate
Norman, A., Ciofu, Oana, Amador, C. I., Høiby, Niels & Jelsbak, L., 2016, In: Genome Announcements. 4, 1, e00008-16.Research output: Contribution to journal › Journal article › Research
- Published
Bacterial evolution in PCD and CF patients follows the same mutational steps
Sommer, L. M., Alanin, M. C., Marvig, R. L., Nielsen, Kim G., Høiby, Niels, von Buchwald, Christian, Molin, S. & Johansen, Helle Krogh, 2016, In: Scientific Reports. 6, 8 p., 28732.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The phagocytic fitness of leucopatches may impact the healing of chronic wounds
Thomsen, K., Trøstrup, H., Christophersen, L., Lundquist, R., Høiby, Niels & Moser, Claus Ernst, 2016, In: Clinical and Experimental Immunology. 184, 3, p. 368-77 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model
Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils
Thomsen, K., Christophersen, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, Claus Ernst & Høiby, Niels, Jul 2016, In: Human Vaccines & Immunotherapeutics. 12, 7, p. 1690-1699 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Animal models of chronic wound care: the application of biofilms in clinical research
Trøstrup, H., Thomsen, K., Calum, Henrik Pierre, Høiby, Niels & Moser, Claus Ernst, 2016, In: Chronic Wound Care Management and Research. 3, p. 123-132 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
S100A8/A9 is an important host defence mediator in neuropathic foot ulcers in patients with type 2 diabetes mellitus
Trøstrup, H., Holstein, P., Christophersen, L., Jørgensen, B., Karlsmark, Tonny, Høiby, Niels, Moser, Claus Ernst & Ågren, Magnus, 1 Jul 2016, In: Archives of Dermatological Research. 308, 5, p. 347-355 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
OligoG CF-5/20 disruption of mucoid Pseudomonas aeruginosa biofilm in a murine lung infection model
Wang, H., Song, Z., Ciofu, Oana, Onsøyen, E., Rye, P. D. & Høiby, Niels, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 5, p. 2620-2626 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The phenotypic evolution of pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin
Wassermann, T., Jørgensen, K. M., Ivanyshyn, K., Bjarnsholt, Thomas, Hossein Khademi, S. M., Jelsbak, L., Høiby, Niels & Ciofu, Oana, 1 May 2016, In: Microbiology. 162, 5, p. 865-875 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia
Alanin, M. C., Nielsen, K. G., von Buchwald, Christian, Skov, M., Aanæs, Kasper, Høiby, Niels & Johansen, Helle Krogh, Dec 2015, In: Clinical Microbiology and Infection. 21, 12, p. 1093.e1–1093.e7 7 p., 1093.e.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia
Alanin, M. C., Johansen, Helle Krogh, Aanaes, K., Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G. & von Buchwald, Christian, Jan 2015, In: Acta Oto-Laryngologica. 135, 1, p. 58-63 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiofilm Properties of Acetic Acid
Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model
Cao, B., Christophersen, L., Thomsen, K., Sønderholm, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2015, In: The Journal of antimicrobial chemotherapy. 70, 7, p. 2057-2063 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients
Ciofu, Oana, Tolker-Nielsen, Tim, Jensen, Peter Østrup, Wang, H. & Høiby, Niels, 2015, In: Advanced Drug Delivery Reviews. 85, p. 7-23 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Autofluorescence in samples obtained from chronic biofilm infections – “all that glitters is not gold”
Eickhardt-Dalbøge, S. R., Kragh, K. N., Schrøder, S., Poulsen, Steen Seier, Sillesen, Henrik, Givskov, Michael, Høiby, Niels, Bjarnsholt, Thomas & Alhede, M., 2015, In: Pathogens and Disease. 73, 4, 4 p., ftv012.Research output: Contribution to journal › Letter › Research › peer-review
- Published
ESCMID guideline for the diagnosis and treatment of biofilm infections 2014
Høiby, Niels, Bjarnsholt, Thomas, Moser, C., Bassi, G. L., Coenye, T., Donelli, G., Hall-Stoodley, L., Holá, V., Imbert, C., Kirketerp-Møller, K., Lebeaux, D., Oliver, A., Ullmann, A. J., Williams, C. & ESCMID Study Group for Biofilms (ESGB) and Consulting External Expert Werner Zimmerli, E. S. G. F. B. (. A. C. E. E. W. Z., 14 Jan 2015, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 21, Suppl. 1, p. s1-s25 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection
Jorgensen, K. M., Wassermann, T., Johansen, Helle Krogh, Christiansen, L. E., Molin, S., Høiby, Niels & Ciofu, Oana, Jul 2015, In: Microbiology. 161, 7, p. 1447-1462 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8427
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
Research output: Contribution to journal › Journal article › Research › peer-review
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2836
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
Research output: Contribution to journal › Journal article › Research › peer-review
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
Research output: Contribution to journal › Journal article › Research › peer-review
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