Niels Høiby

Niels Høiby

Professor, No job title

Member of:


    1. Published

      Visualization of the in vivo interaction of a P. aeruginosa biofilm & the innate host cellular response

      van Gennip, M., Christensen, L. D., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    2. Published

      Visualization of in vivo biofilm developing on silicone implants and the interaction with the cellular response

      van Gennip, M., Christensen, L., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    3. Published

      Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo

      van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Qvortrup, Klaus, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Aug 2012, In: Infection and Immunity. 80, 8, p. 2601-2607 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa

      van Gennip, M., Moser, C., Hultqvist, Louise Dahl, Bjarnsholt, Thomas, Calum, H., Jensen, Peter Østrup, Christophersen, L., Hougen, H. P., Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Dec 2009, In: Journal of Antimicrobial Chemotherapy. 64, 6, p. 1241-50 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Respiratory syncytial virus infection facilitates acute colonization of Pseudomonas aeruginosa in mice

      de Vrankrijker, A. M. M., Wolfs, T. F. W., Ciofu, Oana, Høiby, Niels, van der Ent, C. K., Poulsen, Steen Seier & Johansen, Helle Krogh, 2009, In: Journal of Medical Virology. 81, 12, p. 2096-103 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Intranasal immunisation with conjugate vaccine protects mice from systemic and respiratory tract infection with Pseudomonas aeruginosa

      Zuercher, A. W., Horn, M. P., Wu, H., Song, Z. J., Bundgaard, C. J., Johansen, Helle Krogh, Høiby, Niels, Marcus, P. & Lang, A. B., 2006, In: Vaccine. 24, 20, p. 4333-4342 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Combination and nanotechnology based pharmaceutical strategies for combating respiratory bacterial biofilm infections

      Zhang, L., Bera, H., Wang, H., Wang, J., Guo, Y., Shi, C., Cun, D., Moser, Claus Ernst, Høiby, Niels & Yang, Mingshi, 2022, In: International Journal of Pharmaceutics. 616, 121507.

      Research output: Contribution to journalReviewResearchpeer-review

    8. Published

      Polysaccharides serve as scaffold of biofilms formed by mucoid Pseudomonas aeruginosa

      Yang, L., Hengzhuang, W., Wu, H., Damkiaer, S., Jochumsen, N., Song, Z., Givskov, Michael, Høiby, Niels & Molin, S., Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 366-376 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Combating biofilms

      Yang, L., Liu, Y., Wu, H., Song, Z., Høiby, Niels, Molin, S. & Givskov, Michael, 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 146–157

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Pattern differentiation in co-culture biofilms formed by Staphylococcus aureus and Pseudomonas aeruginosa

      Yang, L., Liu, Y., Markussen, T., Høiby, Niels, Tolker-Nielsen, Tim & Molin, S., 1 Aug 2011, In: F E M S Immunology and Medical Microbiology. 62, 3, p. 339-47 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Current understanding of multi-species biofilms

      Yang, L., Liu, Y., Wu, H., Høiby, Niels, Molin, S. & Song, Z., 1 Apr 2011, In: International Journal of Oral Science. 3, 2, p. 74-81 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Evolutionary dynamics of bacteria in a human host environment

      Yang, L., Jelsbak, L., Marvig, R. L., Damkiær, S., Workman, C., Rau, M. H., Hansen, S. K., Folkesson, A., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels, Sommer, M. & Molin, S., 3 May 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 18, p. 7481-6 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data

      Yang, L., Rau, M. H., Yang, L., Høiby, Niels, Molin, S. & Jelsbak, L., 1 Jan 2011, In: B M C Microbiology. 11, p. 184

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections

      Yang, L., Haagensen, J. A., Jelsbak, L., Sternberg, C., Høiby, Niels, Molin, S. & Johansen, Helle Krogh, 2008, In: Journal of Bacteriology. 190, 8, p. 2767-2776 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Culture-dependent and -independent investigations of microbial diversity on urinary catheters

      Xu, Y., Moser, Claus Ernst, Abu Al-Soud, W., Sørensen, Søren Johannes, Høiby, Niels, Nielsen, P. H. & Thomsen, T. R., 2012, In: Journal of Clinical Microbiology. 50, 12, p. 3901-3908 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Lipocalin 2 is protective against E. coli pneumonia

      Wu, H., Santoni-Rugiu, E., Ralfkiaer, E., Porse, Bo Torben, Moser, Claus Ernst, Høiby, Niels, Borregaard, N. & Cowland, J. B., 2010, In: Respiratory research. 11, p. 96

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Effects of ginseng on Pseudomonas aeruginosa motility and biofilm formation

      Wu, H., Lee, B., Yang, L., Wang, H., Givskov, Michael, Molin, S., Høiby, Niels & Song, Z., 1 Jun 2011, In: F E M S Immunology and Medical Microbiology. 62, 1, p. 49-56 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Ginseng affects motilities of Pseudomonas aeruginosa

      Wu, H., Lee, B. L. R., Yang, L., Givskov, M. C., Molin, S., Høiby, Niels & Song, Z., 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    19. Published

      Lipocalin 2 is protective against E. coli pneumonia

      Wu, H., Santoni Rugiu, Eric, Ralfkiaer, E., Porse, Bo Torben, Moser, C., Høiby, Niels, Borregaard, N., Cowland, J. B., Wu, H., Santoni Rugiu, Eric, Ralfkiær, E., Porse, B. T., Moser, C. E., Høiby, N., Borregaard, N. & Cowland, J., 15 Jun 2010, In: Respiratory research (Online). 11, 96, 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Strategies for combating bacterial biofilm infections

      Wu, H., Moser, Claus Ernst, Wang, H., Høiby, Niels & Song, Z., 2015, In: International Journal of Oral Science. 7, 1, p. 1-7 7 p.

      Research output: Contribution to journalReviewResearchpeer-review

    21. Published

      Effects of Radix Ginseng on microbial infections: a narrative review

      Wu, H., Høiby, Niels, Yang, L., Givskov, Michael & Song, Z., Apr 2014, In: Journal of Traditional Chinese Medicine. 34, 2, p. 227-233 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Effects of antibiotic treatment and phagocyte infiltration on development of Pseudomonas aeruginosa biofilm—Insights from the application of a novel PF hydrogel model in vitro and in vivo

      Wu, H., Song, L., Yam, J. K. H., Plotkin, M., Wang, H., Rybtke, Morten Levin, Seliktar, D., Kofidis, T., Høiby, Niels, Tolker-Nielsen, Tim, Song, Z. & Givskov, Michael, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 826450.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Quorum sensing in Gram-negative bacteria

      Wu, H., Song, Z., Høiby, Niels & Givskov, Michael, May 2004, In: Progress in Natural Science. 14, 5, p. 377-387 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Detection of N-acyl-homoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa

      Wu, H., Song, Z., Hentzer, M., Andersen, J. B., Heydorn, A., Mathee, K., Moser, C., Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146, p. 2481-2493

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Quorum sensing systems contribute to the severity of the lung infection of pseudomonas aeruginosa in rats

      Wu, H., Song, Z. J., Givskov, Michael, Mathee, K., Rygaard, J. & Høiby, Niels, 1999, In: Pediatric Pulmonology. Suppl 19, p. 269-269

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      The N-acyl-homoserine lactones from Pseudomonas aeruginosa can be monitored by green flourescent protein in vivo

      Wu, H., Song, Z. J., Lindum, P. W., Moser, C., Givskov, Michael & Høiby, Niels, 1999, In: Netherlands Journal of Medicine. 54, p. 42-42

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Pseudomonas aeruginosa mutations in lasI and rhlI quorum sensing systems result in milder chronic lung infection

      Wu, H., Song, Z., Givskov, Michael, Doring, G., Worlitzsch, D., Mathee, K., Rygaard, J. & Høiby, Niels, 2001, In: Microbiology. 147, Pt 5, p. 1105-1113 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa

      Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Heydorn, A., Mathee, K., Moser, Claus Ernst, Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146 ( Pt 10), p. 2481-93 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice

      Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Molin, S., Givskov, Michael & Høiby, Niels, 2004, In: Journal of Antimicrobial Chemotherapy. 53, 6, p. 1054-61 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Direct sequencing and RipSeq interpretation as a tool for identification of polymicrobial infections

      Wolff, T. Y., Eickhardt, S., Björnsdottir, M. K., Moser, Claus Ernst, Bjarnsholt, Thomas, Høiby, Niels & Thomsen, T. R., Apr 2013, In: Journal of Clinical Microbiology. 51, 4, p. 1281-4 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Detection of microbial diversity in endocarditis using cultivation-independent molecular techniques

      Wolff, T. Y., Moser, Claus Ernst, Bundgaard, H., Høiby, Niels, Nielsen, P. H. & Thomsen, T. R., 26 Aug 2011, In: Scandinavian Journal of Infectious Diseases. 43, 11-12, p. 857-869

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      The phenotypic evolution of pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin

      Wassermann, T., Jørgensen, K. M., Ivanyshyn, K., Bjarnsholt, Thomas, Hossein Khademi, S. M., Jelsbak, L., Høiby, Niels & Ciofu, Oana, 1 May 2016, In: Microbiology. 162, 5, p. 865-875 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Imipenem shows time dependent killing of P aeruginosa PAO1 biofilm in vitro and in vivo

      Wang, H., Wu, H., Song, Z. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    34. Published

      Ciprofloxacin shows concentration-dependent killing of P. aeruginosa biofilm in vitro

      Wang, H., Wu, H., Song, Z. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    35. Published

      OligoG CF-5/20 disruption of mucoid Pseudomonas aeruginosa biofilm in a murine lung infection model

      Wang, H., Song, Z., Ciofu, Oana, Onsøyen, E., Rye, P. D. & Høiby, Niels, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 5, p. 2620-2626 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Colistin shows concentration-dependent killing of Pseudomonas aeruginosa biofilm in vitro

      Wang, H., Wu, H., Song, Z. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    37. Published

      Salmonella enterica serovar Typhi and S. Paratyphi A: need to expand the QRDR region?

      Walther-Rasmussen, J. & Høiby, Niels, 2011, In: Epidemiology and Infection. 139, 8, p. 1281-1283 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Class a carbapenemases

      Walther-Rasmussen, J. & Høiby, Niels, 2007, In: Journal of Antimicrobial Chemotherapy. 60, 3, p. 470-482 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      OXA-type carbapenemases

      Walther-Rasmussen, J. & Høiby, Niels, 2006, In: Journal of Antimicrobial Chemotherapy. 57, 3, p. 373-383 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Plasmid-borne AmpC beta-lactamase

      Walter-Rasmussen, J. & Høiby, Niels, 2002, In: Canadian Journal of Microbiology. 48, p. 479-493

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes

      Van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Phipps, R., Jensen, Peter Østrup, Christophersen, L., Pamp, S. J., Moser, C., Mikkelsen, P. J., Koh, A. Y., Tolker-Nielsen, Tim, Pier, G. B., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Jul 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 7, p. 537-46 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Relative contribution of Prevotella intermedia and Pseudomonas aeruginosa to lung pathology in airways of patients with cystic fibrosis

      Ulrich, M., Beer, I., Braitmaier, P., Dierkes, M., Kummer, F., Krismer, B., Schumacher, U., Gräpler-Mainka, U., Riethmüller, J., Jensen, Peter Østrup, Bjarnsholt, Thomas, Høiby, Niels, Bellon, G. & Döring, G., 1 Nov 2010, In: Thorax. 65, 11, p. 978-984 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      The clonal antibody response to Pseudomonas aeruginosa heat shock protein is highly diverse in cystic fibrosis patients.

      Ulanova, M., Petersen, T. D., Ciofu, Oana, Jensen, P., Hahn-Zoric, M., Hanson, L. A. & Høiby, Niels, 1997, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 105, 6, p. 449-56 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Forekomst og behandling af Clostridium difficile-associeret diarre

      Tvede, M. & Høiby, Niels, 2006, In: Ugeskrift for læger. 168, 26-32, p. 2579-2580 1 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Kittelbogen medicin.dk

      Tvede, M. & Høiby, Niels, 2007, In: Ugeskrift for læger. 169, 35, p. 2904-

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Antibiotika resistens hos E. coli isoleret fra raske normalpersoner

      Tvede, M., Høiby, Niels, Agerholm Larsen, L., Raben, A. & Astrup, A., 2001, In: Ugeskrift for læger. 163, 36, p. 4868-4871 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor

      Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Feb 2018, In: International Wound Journal. 15, 1, p. 123-132

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Animal models of chronic wound care: the application of biofilms in clinical research

      Trøstrup, H., Thomsen, K., Calum, Henrik Pierre, Høiby, Niels & Moser, Claus Ernst, 2016, In: Chronic Wound Care Management and Research. 3, p. 123-132 10 p.

      Research output: Contribution to journalReviewResearchpeer-review

    49. Published

      Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines—implications for delayed wound closure?

      Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Oct 2017, In: Pathogens and Disease. 75, 7, 10 p., ftx068.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model

      Trøstrup, H., Thomsen, K., Christophersen, L. J., Hougen, H. P., Bjarnsholt, Thomas, Jensen, Peter Østrup, Kirkby, N., Calum, H., Høiby, Niels & Moser, Claus Ernst, Mar 2013, In: Wound Repair and Regeneration. 21, 2, p. 292-299 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds

      Trøstrup, H., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Molecular Sciences. 18, 7, 13 p., 1359.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      S100A8/A9 is an important host defence mediator in neuropathic foot ulcers in patients with type 2 diabetes mellitus

      Trøstrup, H., Holstein, P., Christophersen, L., Jørgensen, B., Karlsmark, Tonny, Høiby, Niels, Moser, Claus Ernst & Ågren, Magnus, 1 Jul 2016, In: Archives of Dermatological Research. 308, 5, p. 347-355 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      S100A8/A9 WOUND FLUID LEVELS ARE REDUCED IN NON-HEALING VENOUS LEG ULCERS COMPARED WITH NEUROPATHIC FOOT ULCERS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

      Trostrup, H., Laursen, A. C., Holstein, P., Christophersen, L., Jorgensen, B., Karlsmark, Tonny, Høiby, Niels, Moser, Claus Ernst & Agren, M. S., 2015, In: Wound Repair and Regeneration. 23, 4, p. A31-A31 1 p.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    54. Published

      PSEUDOMONAS AERUGINOSA BIOFILM INFECTION SUPPRESSES LOCAL HOST RESPONSE IN BURN WOUNDS

      Trostrup, H., Lerche, C. J., Christophersen, L., Thomsen, K., Jensen, P. O., Høiby, Niels & Moser, Claus Ernst, 2015, In: Wound Repair and Regeneration. 23, 4, p. A31-A31 1 p.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    55. Published

      Mannan-binding lectin is a determinant of survival in infective endocarditis

      Tran, C. T., Kjeldsen, K. E., Haunsø, Stig, Høiby, Niels, Johansen, Helle Krogh & Christiansen, M., 2007, In: Clinical and Experimental Immunology. 148, 1, p. 101-105 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. Published

      Pseudomonas aeruginosa diversity in distinct paediatric patient groups

      Tramper-Stranders, G. A., Ent, C. K. V. D., Wolfs, T. F., Kimpen, J. L., Fleer, A., Johansen, U., Høiby, Niels & Johansen, Helle Krogh, 2008, In: Clinical Microbiology and Infection. 14, 10, p. 935-941 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. Published

      Extracellular DNA and F-actin as targets in antibiofilm cystic fibrosis therapy

      Tolker-Nielsen, Tim & Høiby, Niels, 2009, In: Future Microbiology. 4, p. 645-7 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Chronic urinary tract infections in patients with spinal cord lesions – biofilm infection with need for long-term antibiotic treatment

      Tofte, N., Nielsen, A. C. Y., Trøstrup, H., Andersen, C. B., Von Linstow, M., Hansen, B., Biering-Sørensen, Fin, Høiby, Niels & Moser, Claus Ernst, Apr 2017, In: APMIS. 125, 4, p. 385-391 7 p.

      Research output: Contribution to journalReviewResearchpeer-review

    59. Published

      Immune Response to Biofilm Growing Pulmonary Pseudomonas aeruginosa Infection

      Thomsen, K., Høiby, Niels, Jensen, Peter Østrup, Ciofu, Oana & Moser, Claus Ernst, 2022, In: Biomedicines. 10, 9, 2064.

      Research output: Contribution to journalReviewResearchpeer-review

    60. Published

      Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils

      Thomsen, K., Christophersen, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, Claus Ernst & Høiby, Niels, Jul 2016, In: Human Vaccines & Immunotherapeutics. 12, 7, p. 1690-1699 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    61. Published

      Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

      Thomsen, K., Kobayashi, O., Kishi, K., Shirai, R., Jensen, Peter Østrup, Heydorn, A., Hentzer, M., Calum, Henrik Pierre, Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 7, p. 458-476

      Research output: Contribution to journalReviewResearchpeer-review

    62. Published

      Azithromycin potentiates avian IgY effect against Pseudomonas aeruginosa in a murine pulmonary infection model

      Thomsen, K., Christophersen, L., Lerche, C. J., Holmgaard, D. B., Calum, Henrik Pierre, Høiby, Niels & Moser, Claus Ernst, 2021, In: International Journal of Antimicrobial Agents. 57, 1, 106213.

      Research output: Contribution to journalJournal articleResearchpeer-review

    63. Published

      Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils

      Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Jul 2015, In: Infection and Immunity. 83, 7, p. 2686-2693 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    64. Published

      Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model

      Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    65. Published

      The phagocytic fitness of leucopatches may impact the healing of chronic wounds

      Thomsen, K., Trøstrup, H., Christophersen, L., Lundquist, R., Høiby, Niels & Moser, Claus Ernst, 2016, In: Clinical and Experimental Immunology. 184, 3, p. 368-77 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    66. Published

      Comparative genomic analysis of rapid evolution of an extreme-drug- resistant Acinetobacter baumannii clone

      Tan, S., Chua, S. L., Liu, Y., Høiby, Niels, Andersen, L. P., Givskov, Michael, Song, Z. & Yang, L., 2013, In: Genome Biology and Evolution. p. 807–818

      Research output: Contribution to journalJournal articleResearchpeer-review

    67. Published

      Acetic acid and a buffer

      Bjarnsholt, Thomas, Givskov, Michael, P, H., Høiby, Niels, PO, J., HK, J. & K, K., 2010, Patent No. WO2009155931, 30 Jan 2010

      Research output: Patent

    68. Published

      Pseudomonas aeruginosa alginate is refractory to Th1 immune response and impedes host immune clearance in a mouse model of acute lung infection.

      Song, Z., Wu, H., Ciofu, Oana, Kong, K., Høiby, Niels, Rygaard, J., Kharazmi, A. & Mathee, K., 2003, In: Journal of Medical Microbiology. 52, Pt 9, p. 731-40 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    69. Published

      Prosthesis infections after orthopedic joint replacement: the possible role of bacterial biofilms

      Song, Z., Borgwardt, L., Høiby, Niels, Wu, H., Sørensen, T. S. & Borgwardt, A., 7 Jun 2013, In: Orthopedic Reviews. 5, 2, p. 65-71 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    70. Published

      Activation of the immune defence in blood and lung after ginseng treatment in a rat model with chronic Pseudomonas aeruginosa pneumonia

      Song, Z. J., Wu, H., Kharazmi, A., Faber, V., Moser, C., Johansen, Helle Krogh & Høiby, Niels, 1999, In: Netherlands Journal of Medicine. 54, p. 70-70

      Research output: Contribution to journalJournal articleResearchpeer-review

    71. Published

      Gerimax Ginseng regulates both humoral and cellular immunity during chronic Pseudomonas aeruginosa lung infection

      Song, Z. J., Wu, H., Mathee, K., Høiby, Niels & Kharazmi, A., 2002, In: Journal of Alternative & Complementary Medicine. 8, p. 459-466

      Research output: Contribution to journalJournal articleResearchpeer-review

    72. Published

      Effects of Radix angelicae sinensis and Shuanghuanglian on a rat model of chronic Pseudomonas aeruginosa pneumonia

      Song, Z. J., Johansen, Helle Krogh, Moser, C., Faber, V., Kharazmi, A., Rygaard, J. & Høiby, Niels, 2000, In: Chinese Medical Sciences Journal. 15(2), p. 83-88

      Research output: Contribution to journalJournal articleResearchpeer-review

    73. Published

      Cytokine modulating effect of ginseng treatment in a mouse model of Pseudomonas aeruginosa lung infection

      Song, Z. J., Moser, C., Wu, H., Faber, V., Kharazmi, A. & Høiby, Niels, 1999, In: Pediatr Pulmonol. Suppl 19, p. 269-269

      Research output: Contribution to journalJournal articleResearchpeer-review

    74. Published

      Immunomodulatory properties of ginseng. Effects on P. aeruginosa lung infection

      Song, Z. J., Kharazmi, A., Wu, H., Moser, C., Johansen, Helle Krogh, Faber, V. & Høiby, Niels, 1999, In: Clinical Microbiology and Infection. 5, p. 537-538

      Research output: Contribution to journalJournal articleResearchpeer-review

    75. Published

      Ginseng modulerer immunresponset via påvirkning af cytokinproduktionen

      Song, Z., Moser, C., Wu, H., Larsen, M. W., Johansen, Helle Krogh, Faber, V., Kharazmi, A. & Høiby, Niels, 2005, In: Ugeskrift for læger. 167, p. 3054-3056

      Research output: Contribution to journalJournal articleResearchpeer-review

    76. Published

      Effect of ginseng treatment on neutrophil chemiluminescence and IgG subclasses in a rat model of chronic Pseudomonas aeruginosa pneumonia

      Song, Z., Kharazmi, A., Wu, H., Moser, C., Johansen, Helle Krogh, Faber, V., Rygaard, J. & Høiby, Niels, 1998, In: Clinical and Vaccine Immunology. 5, p. 882-887

      Research output: Contribution to journalJournal articleResearchpeer-review

    77. Published

      Panax ginseng has anti-infective activity against opportunistic pathogen Pseudomonas aeruginosa by inhibiting quorum sensing, a bacterial communication process critical for establishing infection

      Song, Z., Kong, K. F., Wu, H., Maricic, N., Ramalingam, B., Priestap, H., Schneper, L., Quirke, J. M. E., Høiby, Niels & Mathee, K., 1 Nov 2010, In: Phytomedicine. 17, 13, p. 1040-6 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    78. Published

      Ginseng treatment reduces bacterial load and lung pathology in chronic Pseudomonas aeruginosa pneumonia in rats

      Song, Z., Johansen, H. K., Faber, V., Moser, C., Kharazmi, A., Rygaard, J. & Høiby, Niels, 1997, In: Antimicrobial Agents and Chemotherapy. 41, 5, p. 961-4 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    79. Published

      Bacterial evolution in PCD and CF patients follows the same mutational steps

      Sommer, L. M., Alanin, M. C., Marvig, R. L., Nielsen, Kim G., Høiby, Niels, von Buchwald, Christian, Molin, S. & Johansen, Helle Krogh, 2016, In: Scientific Reports. 6, 8 p., 28732.

      Research output: Contribution to journalJournal articleResearchpeer-review

    80. Published

      The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

      Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    81. Published

      Specific IgG subclass antibody pattern to Aspergillus fumigatus in patients with cystic fibrosis with allergic bronchopulmonary aspergillosis (ABPA)

      Skov, M., Pressler, T. T., Jensen, H. E., Høiby, Niels & Koch, C., 1999, In: Thorax. 54(1), p. 44-50

      Research output: Contribution to journalJournal articleResearchpeer-review

    82. Published

      Itraconazole treatment of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis

      Skov, M., Høiby, Niels & Koch, C., 2002, In: Allergy. European Journal of Allergy and Clinical Immunology. 57, p. 723-728

      Research output: Contribution to journalJournal articleResearchpeer-review

    83. Published

      Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa

      Skindersoe, M. E., Alhede, M., Phipps, R., Yang, L., Jensen, P. O., Rasmussen, T. B., Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 1 Oct 2008, In: Antimicrobial Agents and Chemotherapy. 52, 10, p. 3648-63 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    84. Published

      Pseudomonas aeruginosa antibody response in cystic fibrosis decreases rapidly following lung transplantation

      Schwensen, H. F., Moser, Claus Ernst, Perch, Michael, Pressler, T. & Høiby, Niels, 2020, In: Journal of Cystic Fibrosis. 19, 4, p. 587-594

      Research output: Contribution to journalJournal articleResearchpeer-review

    85. Published

      A systematic review of studies on the faecal microbiota in anorexia nervosa: future research may need to include microbiota from the small intestine

      Schwensen, H. F., Kan, C., Treasure, J., Høiby, Niels & Sjögren, M., 2018, In: Eating and Weight Disorders. 23, 4, p. 399-418

      Research output: Contribution to journalReviewResearchpeer-review

    86. Published

      Novel human in vitro vegetation simulation model for infective endocarditis

      Schwartz, F. A., Christophersen, L., Laulund, A. S., Lundquist, R., Lerche, C., Rude Nielsen, P., Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2021, In: APMIS. 129, 11, p. 653-662 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    87. Published

      Distinct contribution of hyperbaric oxygen therapy to human neutrophil function and antibiotic efficacy against Staphylococcus aureus

      Schwartz, F. A., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Laulund, A. S., Woetmann, Anders , Høiby, Niels & Moser, Claus Ernst, 2021, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 129, 9, p. 566-573

      Research output: Contribution to journalJournal articleResearchpeer-review

    88. Published

      Chicken IgY reduces the risk of Pseudomonas aeruginosa urinary tract infections in a murine model

      Schwartz, F. A., Christophersen, L., Thomsen, K., Baekdal, S., Pals Bendixen, M., Jørgensen, M., Bull Rasmussen, I. K., Laulund, A. S., Høiby, Niels & Moser, Claus Ernst, 2022, In: Frontiers in Microbiology. 13, 988386.

      Research output: Contribution to journalJournal articleResearchpeer-review

    89. Published

      Dynamics of a Staphylococcus aureus infective endocarditis simulation model

      Schwartz, F. A., Nielsen, L., Struve Andersen, J., Bock, M., Christophersen, L., Sunnerhagen, T., Lerche, C. J., Bay, Lene, Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 8, p. 515-523

      Research output: Contribution to journalJournal articleResearchpeer-review

    90. Published

      Individual pharmacokinetic variation leads to underdosing of ciprofloxacin in some cystic fibrosis patients

      Schultz, A. N. Ø., Høiby, Niels, Nielsen, X. C., Pressler, T., Dalhoff, Kim, Duno, M., Buchard, Anders, Johansen, H. K., Wang, H. & Dalbøge, C. S., Mar 2017, In: Pediatric Pulmonology. 52, 3, p. 319-323 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    91. Published

      C3 polymorphism in a Danish cystic fibrosis population and its possible association with antibody response

      Schiøtz, P. O., Høiby, Niels, Morling, Niels & Sørensen, H., 1978, In: Human Heredity. 28, 4, p. 293-300 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    92. Published

      A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production

      Sautter, R., Ramos, D., Schneper, L., Ciofu, Oana, Wassermann, T., Koh, C., Heydorn, A., Hentzer, M., Høiby, Niels, Kharazmi, A., Molin, S., Devries, C. A., Ohman, D. E. & Mathee, K., 1 May 2012, In: Gene. 498, 2, p. 242-253 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    93. Published

      Typing of Pseudomonas aeruginosa from hemorrhagic pneumonia in mink (Neovison vison)

      Salomonsen, C. M., Themudo, G. E., Jelsbak, L., Molin, S., Høiby, Niels & Hammer, Anne Sofie Vedsted, 2013, In: Veterinary Microbiology. 163, 1-2, p. 103-109 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    94. Published

      Effect of infectious dose and season on development of hemorrhagic pneumonia in mink caused by Pseudomonas aeruginosa

      Salomonsen, C. M., Chriél, M., Jensen, T. H., Rangstrup-Christensen, L., Høiby, Niels & Hammer, Anne Sofie Vedsted, 2013, In: Canadian Journal of Veterinary Research. 77, 3, p. 221-225 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    95. Published

      Infection control in cystic fibrosis: Practical recommendations for the hospital, clinic and social settings

      Saiman, L., MacDonald, N., Burns, J. L., Høiby, Niels, Speert, D. & Weber, D., 2000, In: American Journal of Infection Control. 28, p. 381-385

      Research output: Contribution to journalJournal articleResearchpeer-review

    96. Published

      Chronic infection with Achromobacter xylosoxidans in cystic fibrosis patients; a retrospective case control study

      Rønne Hansen, C., Pressler, T., Høiby, Niels & Gormsen, M., 2006, In: Journal of Cystic Fibrosis. 5, 4, p. 245-51 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    97. Published

      The implication of Pseudomonas aeruginosa biofilms in infections

      Rybtke, Morten Levin, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: Inflammation & Allergy - Drug Targets. 10, 2, p. 141-57 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    98. Published

      The LapG protein plays a role in Pseudomonas aeruginosa biofilm formation by controlling the presence of the CdrA adhesin on the cell surface

      Rybtke, Morten Levin, Berthelsen, J., Yang, L., Høiby, Niels, Givskov, Michael & Tolker-Nielsen, Tim, Dec 2015, In: MicrobiologyOpen. 4, 6, p. 917-930 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    99. Published

      True microbiota involved in chronic lung infection of cystic fibrosis patients found by culturing and 16S rRNA gene analysis

      Rudkjøbing, V. B., Thomsen, T. R., Alhede, M., Kragh, K. N., Nielsen, P. H., Johansen, U., Givskov, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2011, In: Journal of Clinical Microbiology. 49, 12, p. 4352-5 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    100. Published

      The microorganisms in chronically infected end-stage and non-end-stage cystic fibrosis patients

      Rudkjøbing, V. B., Thomsen, T. R., Alhede, M., Kragh, K. N., Nielsen, P. H., Johansen, U. R., Givskov, Michael, Høiby, Niels & Bjarnsholt, Thomas, Jul 2011, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 236-244 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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