Niels Høiby
Professor, No job title
Bacteriology
Blegdamsvej 3B, 2200 København N, 24 Bygning 24, Building: 24-1-16
Member of:
- Published
Visualization of the in vivo interaction of a P. aeruginosa biofilm & the innate host cellular response
van Gennip, M., Christensen, L. D., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Visualization of in vivo biofilm developing on silicone implants and the interaction with the cellular response
van Gennip, M., Christensen, L., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo
van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Qvortrup, Klaus, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Aug 2012, In: Infection and Immunity. 80, 8, p. 2601-2607 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa
van Gennip, M., Moser, C., Hultqvist, Louise Dahl, Bjarnsholt, Thomas, Calum, H., Jensen, Peter Østrup, Christophersen, L., Hougen, H. P., Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Dec 2009, In: Journal of Antimicrobial Chemotherapy. 64, 6, p. 1241-50 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Respiratory syncytial virus infection facilitates acute colonization of Pseudomonas aeruginosa in mice
de Vrankrijker, A. M. M., Wolfs, T. F. W., Ciofu, Oana, Høiby, Niels, van der Ent, C. K., Poulsen, Steen Seier & Johansen, Helle Krogh, 2009, In: Journal of Medical Virology. 81, 12, p. 2096-103 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intranasal immunisation with conjugate vaccine protects mice from systemic and respiratory tract infection with Pseudomonas aeruginosa
Zuercher, A. W., Horn, M. P., Wu, H., Song, Z. J., Bundgaard, C. J., Johansen, Helle Krogh, Høiby, Niels, Marcus, P. & Lang, A. B., 2006, In: Vaccine. 24, 20, p. 4333-4342 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combination and nanotechnology based pharmaceutical strategies for combating respiratory bacterial biofilm infections
Zhang, L., Bera, H., Wang, H., Wang, J., Guo, Y., Shi, C., Cun, D., Moser, Claus Ernst, Høiby, Niels & Yang, Mingshi, 2022, In: International Journal of Pharmaceutics. 616, 121507.Research output: Contribution to journal › Review › Research › peer-review
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Polysaccharides serve as scaffold of biofilms formed by mucoid Pseudomonas aeruginosa
Yang, L., Hengzhuang, W., Wu, H., Damkiaer, S., Jochumsen, N., Song, Z., Givskov, Michael, Høiby, Niels & Molin, S., Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 366-376 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combating biofilms
Yang, L., Liu, Y., Wu, H., Song, Z., Høiby, Niels, Molin, S. & Givskov, Michael, 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 146–157Research output: Contribution to journal › Journal article › Research › peer-review
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Pattern differentiation in co-culture biofilms formed by Staphylococcus aureus and Pseudomonas aeruginosa
Yang, L., Liu, Y., Markussen, T., Høiby, Niels, Tolker-Nielsen, Tim & Molin, S., 1 Aug 2011, In: F E M S Immunology and Medical Microbiology. 62, 3, p. 339-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Current understanding of multi-species biofilms
Yang, L., Liu, Y., Wu, H., Høiby, Niels, Molin, S. & Song, Z., 1 Apr 2011, In: International Journal of Oral Science. 3, 2, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evolutionary dynamics of bacteria in a human host environment
Yang, L., Jelsbak, L., Marvig, R. L., Damkiær, S., Workman, C., Rau, M. H., Hansen, S. K., Folkesson, A., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels, Sommer, M. & Molin, S., 3 May 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 18, p. 7481-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data
Yang, L., Rau, M. H., Yang, L., Høiby, Niels, Molin, S. & Jelsbak, L., 1 Jan 2011, In: B M C Microbiology. 11, p. 184Research output: Contribution to journal › Journal article › Research › peer-review
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In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections
Yang, L., Haagensen, J. A., Jelsbak, L., Sternberg, C., Høiby, Niels, Molin, S. & Johansen, Helle Krogh, 2008, In: Journal of Bacteriology. 190, 8, p. 2767-2776 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Culture-dependent and -independent investigations of microbial diversity on urinary catheters
Xu, Y., Moser, Claus Ernst, Abu Al-Soud, W., Sørensen, Søren Johannes, Høiby, Niels, Nielsen, P. H. & Thomsen, T. R., 2012, In: Journal of Clinical Microbiology. 50, 12, p. 3901-3908 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipocalin 2 is protective against E. coli pneumonia
Wu, H., Santoni-Rugiu, E., Ralfkiaer, E., Porse, Bo Torben, Moser, Claus Ernst, Høiby, Niels, Borregaard, N. & Cowland, J. B., 2010, In: Respiratory research. 11, p. 96Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of ginseng on Pseudomonas aeruginosa motility and biofilm formation
Wu, H., Lee, B., Yang, L., Wang, H., Givskov, Michael, Molin, S., Høiby, Niels & Song, Z., 1 Jun 2011, In: F E M S Immunology and Medical Microbiology. 62, 1, p. 49-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ginseng affects motilities of Pseudomonas aeruginosa
Wu, H., Lee, B. L. R., Yang, L., Givskov, M. C., Molin, S., Høiby, Niels & Song, Z., 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Lipocalin 2 is protective against E. coli pneumonia
Wu, H., Santoni Rugiu, Eric, Ralfkiaer, E., Porse, Bo Torben, Moser, C., Høiby, Niels, Borregaard, N., Cowland, J. B., Wu, H., Santoni Rugiu, Eric, Ralfkiær, E., Porse, B. T., Moser, C. E., Høiby, N., Borregaard, N. & Cowland, J., 15 Jun 2010, In: Respiratory research (Online). 11, 96, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Strategies for combating bacterial biofilm infections
Wu, H., Moser, Claus Ernst, Wang, H., Høiby, Niels & Song, Z., 2015, In: International Journal of Oral Science. 7, 1, p. 1-7 7 p.Research output: Contribution to journal › Review › Research › peer-review
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Effects of Radix Ginseng on microbial infections: a narrative review
Wu, H., Høiby, Niels, Yang, L., Givskov, Michael & Song, Z., Apr 2014, In: Journal of Traditional Chinese Medicine. 34, 2, p. 227-233 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of antibiotic treatment and phagocyte infiltration on development of Pseudomonas aeruginosa biofilm—Insights from the application of a novel PF hydrogel model in vitro and in vivo
Wu, H., Song, L., Yam, J. K. H., Plotkin, M., Wang, H., Rybtke, Morten Levin, Seliktar, D., Kofidis, T., Høiby, Niels, Tolker-Nielsen, Tim, Song, Z. & Givskov, Michael, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 826450.Research output: Contribution to journal › Journal article › Research › peer-review
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Quorum sensing in Gram-negative bacteria
Wu, H., Song, Z., Høiby, Niels & Givskov, Michael, May 2004, In: Progress in Natural Science. 14, 5, p. 377-387 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of N-acyl-homoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa
Wu, H., Song, Z., Hentzer, M., Andersen, J. B., Heydorn, A., Mathee, K., Moser, C., Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146, p. 2481-2493Research output: Contribution to journal › Journal article › Research › peer-review
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Quorum sensing systems contribute to the severity of the lung infection of pseudomonas aeruginosa in rats
Wu, H., Song, Z. J., Givskov, Michael, Mathee, K., Rygaard, J. & Høiby, Niels, 1999, In: Pediatric Pulmonology. Suppl 19, p. 269-269Research output: Contribution to journal › Journal article › Research › peer-review
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The N-acyl-homoserine lactones from Pseudomonas aeruginosa can be monitored by green flourescent protein in vivo
Wu, H., Song, Z. J., Lindum, P. W., Moser, C., Givskov, Michael & Høiby, Niels, 1999, In: Netherlands Journal of Medicine. 54, p. 42-42Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas aeruginosa mutations in lasI and rhlI quorum sensing systems result in milder chronic lung infection
Wu, H., Song, Z., Givskov, Michael, Doring, G., Worlitzsch, D., Mathee, K., Rygaard, J. & Høiby, Niels, 2001, In: Microbiology. 147, Pt 5, p. 1105-1113 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa
Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Heydorn, A., Mathee, K., Moser, Claus Ernst, Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146 ( Pt 10), p. 2481-93 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice
Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Molin, S., Givskov, Michael & Høiby, Niels, 2004, In: Journal of Antimicrobial Chemotherapy. 53, 6, p. 1054-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct sequencing and RipSeq interpretation as a tool for identification of polymicrobial infections
Wolff, T. Y., Eickhardt, S., Björnsdottir, M. K., Moser, Claus Ernst, Bjarnsholt, Thomas, Høiby, Niels & Thomsen, T. R., Apr 2013, In: Journal of Clinical Microbiology. 51, 4, p. 1281-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of microbial diversity in endocarditis using cultivation-independent molecular techniques
Wolff, T. Y., Moser, Claus Ernst, Bundgaard, H., Høiby, Niels, Nielsen, P. H. & Thomsen, T. R., 26 Aug 2011, In: Scandinavian Journal of Infectious Diseases. 43, 11-12, p. 857-869Research output: Contribution to journal › Journal article › Research › peer-review
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The phenotypic evolution of pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin
Wassermann, T., Jørgensen, K. M., Ivanyshyn, K., Bjarnsholt, Thomas, Hossein Khademi, S. M., Jelsbak, L., Høiby, Niels & Ciofu, Oana, 1 May 2016, In: Microbiology. 162, 5, p. 865-875 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Imipenem shows time dependent killing of P aeruginosa PAO1 biofilm in vitro and in vivo
Wang, H., Wu, H., Song, Z. & Høiby, Niels, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Ciprofloxacin shows concentration-dependent killing of P. aeruginosa biofilm in vitro
Wang, H., Wu, H., Song, Z. & Høiby, Niels, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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OligoG CF-5/20 disruption of mucoid Pseudomonas aeruginosa biofilm in a murine lung infection model
Wang, H., Song, Z., Ciofu, Oana, Onsøyen, E., Rye, P. D. & Høiby, Niels, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 5, p. 2620-2626 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Colistin shows concentration-dependent killing of Pseudomonas aeruginosa biofilm in vitro
Wang, H., Wu, H., Song, Z. & Høiby, Niels, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Salmonella enterica serovar Typhi and S. Paratyphi A: need to expand the QRDR region?
Walther-Rasmussen, J. & Høiby, Niels, 2011, In: Epidemiology and Infection. 139, 8, p. 1281-1283 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Class a carbapenemases
Walther-Rasmussen, J. & Høiby, Niels, 2007, In: Journal of Antimicrobial Chemotherapy. 60, 3, p. 470-482 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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OXA-type carbapenemases
Walther-Rasmussen, J. & Høiby, Niels, 2006, In: Journal of Antimicrobial Chemotherapy. 57, 3, p. 373-383 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmid-borne AmpC beta-lactamase
Walter-Rasmussen, J. & Høiby, Niels, 2002, In: Canadian Journal of Microbiology. 48, p. 479-493Research output: Contribution to journal › Journal article › Research › peer-review
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Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes
Van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Phipps, R., Jensen, Peter Østrup, Christophersen, L., Pamp, S. J., Moser, C., Mikkelsen, P. J., Koh, A. Y., Tolker-Nielsen, Tim, Pier, G. B., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Jul 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 7, p. 537-46 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Relative contribution of Prevotella intermedia and Pseudomonas aeruginosa to lung pathology in airways of patients with cystic fibrosis
Ulrich, M., Beer, I., Braitmaier, P., Dierkes, M., Kummer, F., Krismer, B., Schumacher, U., Gräpler-Mainka, U., Riethmüller, J., Jensen, Peter Østrup, Bjarnsholt, Thomas, Høiby, Niels, Bellon, G. & Döring, G., 1 Nov 2010, In: Thorax. 65, 11, p. 978-984 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The clonal antibody response to Pseudomonas aeruginosa heat shock protein is highly diverse in cystic fibrosis patients.
Ulanova, M., Petersen, T. D., Ciofu, Oana, Jensen, P., Hahn-Zoric, M., Hanson, L. A. & Høiby, Niels, 1997, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 105, 6, p. 449-56 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Forekomst og behandling af Clostridium difficile-associeret diarre
Tvede, M. & Høiby, Niels, 2006, In: Ugeskrift for læger. 168, 26-32, p. 2579-2580 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kittelbogen medicin.dk
Tvede, M. & Høiby, Niels, 2007, In: Ugeskrift for læger. 169, 35, p. 2904-Research output: Contribution to journal › Journal article › Research › peer-review
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Antibiotika resistens hos E. coli isoleret fra raske normalpersoner
Tvede, M., Høiby, Niels, Agerholm Larsen, L., Raben, A. & Astrup, A., 2001, In: Ugeskrift for læger. 163, 36, p. 4868-4871 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor
Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Feb 2018, In: International Wound Journal. 15, 1, p. 123-132Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model
Trøstrup, H., Thomsen, K., Christophersen, L. J., Hougen, H. P., Bjarnsholt, Thomas, Jensen, Peter Østrup, Kirkby, N., Calum, H., Høiby, Niels & Moser, Claus Ernst, Mar 2013, In: Wound Repair and Regeneration. 21, 2, p. 292-299 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds
Trøstrup, H., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Molecular Sciences. 18, 7, 13 p., 1359.Research output: Contribution to journal › Journal article › Research › peer-review
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S100A8/A9 is an important host defence mediator in neuropathic foot ulcers in patients with type 2 diabetes mellitus
Trøstrup, H., Holstein, P., Christophersen, L., Jørgensen, B., Karlsmark, Tonny, Høiby, Niels, Moser, Claus Ernst & Ågren, Magnus, 1 Jul 2016, In: Archives of Dermatological Research. 308, 5, p. 347-355 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8427
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
Research output: Contribution to journal › Journal article › Research › peer-review
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