Niels Høiby

Niels Høiby

Professor, No job title

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    ORCID: 0000-0002-1347-725X

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    1. Published

      Visualization of the in vivo interaction of a P. aeruginosa biofilm & the innate host cellular response

      van Gennip, M., Christensen, L. D., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    2. Published

      Visualization of in vivo biofilm developing on silicone implants and the interaction with the cellular response

      van Gennip, M., Christensen, L., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    3. Published

      Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo

      van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Qvortrup, Klaus, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Aug 2012, In: Infection and Immunity. 80, 8, p. 2601-2607 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa

      van Gennip, M., Moser, C., Hultqvist, Louise Dahl, Bjarnsholt, Thomas, Calum, H., Jensen, Peter Østrup, Christophersen, L., Hougen, H. P., Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Dec 2009, In: Journal of Antimicrobial Chemotherapy. 64, 6, p. 1241-50 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Respiratory syncytial virus infection facilitates acute colonization of Pseudomonas aeruginosa in mice

      de Vrankrijker, A. M. M., Wolfs, T. F. W., Ciofu, Oana, Høiby, Niels, van der Ent, C. K., Poulsen, Steen Seier & Johansen, Helle Krogh, 2009, In: Journal of Medical Virology. 81, 12, p. 2096-103 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Intranasal immunisation with conjugate vaccine protects mice from systemic and respiratory tract infection with Pseudomonas aeruginosa

      Zuercher, A. W., Horn, M. P., Wu, H., Song, Z. J., Bundgaard, C. J., Johansen, Helle Krogh, Høiby, Niels, Marcus, P. & Lang, A. B., 2006, In: Vaccine. 24, 20, p. 4333-4342 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Combination and nanotechnology based pharmaceutical strategies for combating respiratory bacterial biofilm infections

      Zhang, L., Bera, H., Wang, H., Wang, J., Guo, Y., Shi, C., Cun, D., Moser, Claus Ernst, Høiby, Niels & Yang, Mingshi, 2022, In: International Journal of Pharmaceutics. 616, 121507.

      Research output: Contribution to journal › Review › Research › peer-review

    8. Published

      Polysaccharides serve as scaffold of biofilms formed by mucoid Pseudomonas aeruginosa

      Yang, L., Hengzhuang, W., Wu, H., Damkiaer, S., Jochumsen, N., Song, Z., Givskov, Michael, Høiby, Niels & Molin, S., Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 366-376 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Combating biofilms

      Yang, L., Liu, Y., Wu, H., Song, Z., Høiby, Niels, Molin, S. & Givskov, Michael, 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 146–157

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Pattern differentiation in co-culture biofilms formed by Staphylococcus aureus and Pseudomonas aeruginosa

      Yang, L., Liu, Y., Markussen, T., Høiby, Niels, Tolker-Nielsen, Tim & Molin, S., 1 Aug 2011, In: F E M S Immunology and Medical Microbiology. 62, 3, p. 339-47 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Current understanding of multi-species biofilms

      Yang, L., Liu, Y., Wu, H., Høiby, Niels, Molin, S. & Song, Z., 1 Apr 2011, In: International Journal of Oral Science. 3, 2, p. 74-81 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Evolutionary dynamics of bacteria in a human host environment

      Yang, L., Jelsbak, L., Marvig, R. L., Damkiær, S., Workman, C., Rau, M. H., Hansen, S. K., Folkesson, A., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels, Sommer, M. & Molin, S., 3 May 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 18, p. 7481-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data

      Yang, L., Rau, M. H., Yang, L., Høiby, Niels, Molin, S. & Jelsbak, L., 1 Jan 2011, In: B M C Microbiology. 11, p. 184

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections

      Yang, L., Haagensen, J. A., Jelsbak, L., Sternberg, C., Høiby, Niels, Molin, S. & Johansen, Helle Krogh, 2008, In: Journal of Bacteriology. 190, 8, p. 2767-2776 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Culture-dependent and -independent investigations of microbial diversity on urinary catheters

      Xu, Y., Moser, Claus Ernst, Abu Al-Soud, W., Sørensen, Søren Johannes, Høiby, Niels, Nielsen, P. H. & Thomsen, T. R., 2012, In: Journal of Clinical Microbiology. 50, 12, p. 3901-3908 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Lipocalin 2 is protective against E. coli pneumonia

      Wu, H., Santoni-Rugiu, E., Ralfkiaer, E., Porse, Bo Torben, Moser, Claus Ernst, Høiby, Niels, Borregaard, N. & Cowland, J. B., 2010, In: Respiratory research. 11, p. 96

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Effects of ginseng on Pseudomonas aeruginosa motility and biofilm formation

      Wu, H., Lee, B., Yang, L., Wang, H., Givskov, Michael, Molin, S., Høiby, Niels & Song, Z., 1 Jun 2011, In: F E M S Immunology and Medical Microbiology. 62, 1, p. 49-56 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Ginseng affects motilities of Pseudomonas aeruginosa

      Wu, H., Lee, B. L. R., Yang, L., Givskov, M. C., Molin, S., Høiby, Niels & Song, Z., 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    19. Published

      Lipocalin 2 is protective against E. coli pneumonia

      Wu, H., Santoni Rugiu, Eric, Ralfkiaer, E., Porse, Bo Torben, Moser, C., Høiby, Niels, Borregaard, N., Cowland, J. B., Wu, H., Santoni Rugiu, Eric, Ralfkiær, E., Porse, B. T., Moser, C. E., Høiby, N., Borregaard, N. & Cowland, J., 15 Jun 2010, In: Respiratory research (Online). 11, 96, 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Strategies for combating bacterial biofilm infections

      Wu, H., Moser, Claus Ernst, Wang, H., Høiby, Niels & Song, Z., 2015, In: International Journal of Oral Science. 7, 1, p. 1-7 7 p.

      Research output: Contribution to journal › Review › Research › peer-review

    21. Published

      Effects of Radix Ginseng on microbial infections: a narrative review

      Wu, H., Høiby, Niels, Yang, L., Givskov, Michael & Song, Z., Apr 2014, In: Journal of Traditional Chinese Medicine. 34, 2, p. 227-233 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Effects of antibiotic treatment and phagocyte infiltration on development of Pseudomonas aeruginosa biofilm—Insights from the application of a novel PF hydrogel model in vitro and in vivo

      Wu, H., Song, L., Yam, J. K. H., Plotkin, M., Wang, H., Rybtke, Morten Levin, Seliktar, D., Kofidis, T., Høiby, Niels, Tolker-Nielsen, Tim, Song, Z. & Givskov, Michael, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 826450.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Quorum sensing in Gram-negative bacteria

      Wu, H., Song, Z., Høiby, Niels & Givskov, Michael, May 2004, In: Progress in Natural Science. 14, 5, p. 377-387 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Detection of N-acyl-homoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa

      Wu, H., Song, Z., Hentzer, M., Andersen, J. B., Heydorn, A., Mathee, K., Moser, C., Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146, p. 2481-2493

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Quorum sensing systems contribute to the severity of the lung infection of pseudomonas aeruginosa in rats

      Wu, H., Song, Z. J., Givskov, Michael, Mathee, K., Rygaard, J. & Høiby, Niels, 1999, In: Pediatric Pulmonology. Suppl 19, p. 269-269

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      The N-acyl-homoserine lactones from Pseudomonas aeruginosa can be monitored by green flourescent protein in vivo

      Wu, H., Song, Z. J., Lindum, P. W., Moser, C., Givskov, Michael & Høiby, Niels, 1999, In: Netherlands Journal of Medicine. 54, p. 42-42

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Pseudomonas aeruginosa mutations in lasI and rhlI quorum sensing systems result in milder chronic lung infection

      Wu, H., Song, Z., Givskov, Michael, Doring, G., Worlitzsch, D., Mathee, K., Rygaard, J. & Høiby, Niels, 2001, In: Microbiology. 147, Pt 5, p. 1105-1113 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa

      Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Heydorn, A., Mathee, K., Moser, Claus Ernst, Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146 ( Pt 10), p. 2481-93 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice

      Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Molin, S., Givskov, Michael & Høiby, Niels, 2004, In: Journal of Antimicrobial Chemotherapy. 53, 6, p. 1054-61 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Direct sequencing and RipSeq interpretation as a tool for identification of polymicrobial infections

      Wolff, T. Y., Eickhardt, S., Björnsdottir, M. K., Moser, Claus Ernst, Bjarnsholt, Thomas, Høiby, Niels & Thomsen, T. R., Apr 2013, In: Journal of Clinical Microbiology. 51, 4, p. 1281-4 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Detection of microbial diversity in endocarditis using cultivation-independent molecular techniques

      Wolff, T. Y., Moser, Claus Ernst, Bundgaard, H., Høiby, Niels, Nielsen, P. H. & Thomsen, T. R., 26 Aug 2011, In: Scandinavian Journal of Infectious Diseases. 43, 11-12, p. 857-869

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      The phenotypic evolution of pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin

      Wassermann, T., Jørgensen, K. M., Ivanyshyn, K., Bjarnsholt, Thomas, Hossein Khademi, S. M., Jelsbak, L., Høiby, Niels & Ciofu, Oana, 1 May 2016, In: Microbiology. 162, 5, p. 865-875 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Imipenem shows time dependent killing of P aeruginosa PAO1 biofilm in vitro and in vivo

      Wang, H., Wu, H., Song, Z. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    34. Published

      Ciprofloxacin shows concentration-dependent killing of P. aeruginosa biofilm in vitro

      Wang, H., Wu, H., Song, Z. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    35. Published

      OligoG CF-5/20 disruption of mucoid Pseudomonas aeruginosa biofilm in a murine lung infection model

      Wang, H., Song, Z., Ciofu, Oana, Onsøyen, E., Rye, P. D. & Høiby, Niels, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 5, p. 2620-2626 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Colistin shows concentration-dependent killing of Pseudomonas aeruginosa biofilm in vitro

      Wang, H., Wu, H., Song, Z. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    37. Published

      Salmonella enterica serovar Typhi and S. Paratyphi A: need to expand the QRDR region?

      Walther-Rasmussen, J. & Høiby, Niels, 2011, In: Epidemiology and Infection. 139, 8, p. 1281-1283 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Class a carbapenemases

      Walther-Rasmussen, J. & Høiby, Niels, 2007, In: Journal of Antimicrobial Chemotherapy. 60, 3, p. 470-482 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      OXA-type carbapenemases

      Walther-Rasmussen, J. & Høiby, Niels, 2006, In: Journal of Antimicrobial Chemotherapy. 57, 3, p. 373-383 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Plasmid-borne AmpC beta-lactamase

      Walter-Rasmussen, J. & Høiby, Niels, 2002, In: Canadian Journal of Microbiology. 48, p. 479-493

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes

      Van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Phipps, R., Jensen, Peter Østrup, Christophersen, L., Pamp, S. J., Moser, C., Mikkelsen, P. J., Koh, A. Y., Tolker-Nielsen, Tim, Pier, G. B., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Jul 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 7, p. 537-46 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Relative contribution of Prevotella intermedia and Pseudomonas aeruginosa to lung pathology in airways of patients with cystic fibrosis

      Ulrich, M., Beer, I., Braitmaier, P., Dierkes, M., Kummer, F., Krismer, B., Schumacher, U., Gräpler-Mainka, U., Riethmüller, J., Jensen, Peter Østrup, Bjarnsholt, Thomas, Høiby, Niels, Bellon, G. & Döring, G., 1 Nov 2010, In: Thorax. 65, 11, p. 978-984 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      The clonal antibody response to Pseudomonas aeruginosa heat shock protein is highly diverse in cystic fibrosis patients.

      Ulanova, M., Petersen, T. D., Ciofu, Oana, Jensen, P., Hahn-Zoric, M., Hanson, L. A. & Høiby, Niels, 1997, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 105, 6, p. 449-56 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Forekomst og behandling af Clostridium difficile-associeret diarre

      Tvede, M. & Høiby, Niels, 2006, In: Ugeskrift for læger. 168, 26-32, p. 2579-2580 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Kittelbogen medicin.dk

      Tvede, M. & Høiby, Niels, 2007, In: Ugeskrift for læger. 169, 35, p. 2904-

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Antibiotika resistens hos E. coli isoleret fra raske normalpersoner

      Tvede, M., Høiby, Niels, Agerholm Larsen, L., Raben, A. & Astrup, A., 2001, In: Ugeskrift for læger. 163, 36, p. 4868-4871 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor

      Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Feb 2018, In: International Wound Journal. 15, 1, p. 123-132

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model

      Trøstrup, H., Thomsen, K., Christophersen, L. J., Hougen, H. P., Bjarnsholt, Thomas, Jensen, Peter Østrup, Kirkby, N., Calum, H., Høiby, Niels & Moser, Claus Ernst, Mar 2013, In: Wound Repair and Regeneration. 21, 2, p. 292-299 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds

      Trøstrup, H., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Molecular Sciences. 18, 7, 13 p., 1359.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      S100A8/A9 is an important host defence mediator in neuropathic foot ulcers in patients with type 2 diabetes mellitus

      Trøstrup, H., Holstein, P., Christophersen, L., Jørgensen, B., Karlsmark, Tonny, Høiby, Niels, Moser, Claus Ernst & Ågren, Magnus, 1 Jul 2016, In: Archives of Dermatological Research. 308, 5, p. 347-355 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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