Niels Høiby

Niels Høiby

Professor, No job title

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    ORCID: 0000-0002-1347-725X

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    1. Published

      Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis

      Dalbøge, C. S., Nielsen, X. C., Dalhoff, K., Alffenaar, J. W., Duno, M., Buchard, Anders, Uges, D. R. A., Jensen, A. G., Jürgens, G., Pressler, T., Johansen, H. K. & Høiby, Niels, Mar 2014, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 13, 2, p. 179-85 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Chronic pulmonary infection with Stenotrophomonas maltophilia and lung function in patients with cystic fibrosis

      Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 1 Sep 2011, In: Journal of Cystic Fibrosis. 10, 5, p. 318-25 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      A cohort study of the Copenhagen CF Centre eradication strategy against Staphylococcus aureus in patients with CF

      Dalbøge, C. S., Pressler, T., Høiby, Niels, Nielsen, Kim G. & Johansen, Helle Krogh, Jan 2013, In: Journal of Cystic Fibrosis. 12, 1, p. 42-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Chronic infection with Stenotrophomonas maltophilia in patients with cystic fibrosis at the Copenhagen CF centre

      Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 17 Jun 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    5. Published

      Effects of antibiotic treatment of Staphylococcus aureus infection in patients with cystic fibrosis at the Copenhagen CF centre

      Dalbøge, C. S., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    6. Published

      Activation of pulmonary and lymph node dendritic cells during chronic Pseudomonas aeruginosa lung infection in mice

      Damlund, D. S. M., Christophersen, L., Jensen, Peter Østrup, Alhede, M., Høiby, Niels & Moser, Claus Ernst, Jun 2016, In: APMIS - Journal of Pathology, Microbiology and Immunology. 124, 6, p. 500-507 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Upregulation of dendritic cells during chronic Pseudomonas aeruginosa lung infection in BALB/c mice

      Damlund, D. S. M., Jensen, Peter Østrup, Christophersen, L. J., Alhede, M., Høiby, Niels & Moser, Claus Ernst, Jun 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    8. Published

      Værnet. Den danske SS-læge i Buchenwald

      Davidsen-Nielsen, H., Høiby, Niels, Danielsen, N. & Rubin, J., 2002, Jyllands-Postens Forlag, JPBøger. 283 p.

      Research output: Book/Report › Book › Research

    9. Published

      Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus

      Döring, G., Conway, S., Heijerman, H. G. M., Hodson, M. E., Høiby, Niels, Smyth, A. & Touw, D. J., 2000, In: European Respiratory Journal. 16, p. 749-767

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Treatment of lung infection in patients with cystic fibrosis: current and future strategies

      Döring, G., Flume, P., Heijerman, H., Elborn, J. S. & Consensus Study Group, C. S. G., Dec 2012, In: Journal of Cystic Fibrosis. 11, 6, p. 461-479 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      A non-fatal case of invasive zygomycete (Lichtheimia corymbifera) infection in an allogeneic haematopoietic cell transplant recipient

      Eickhardt, S., Braendstrup, P., Clasen-Linde, E., Jensen, K. E., Alhede, M., Bjarnsholt, Thomas, Høiby, Niels, Vindeløv, L. & Moser, Claus Ernst, May 2013, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 121, 5, p. 456-9 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Autofluorescence in samples obtained from chronic biofilm infections – “all that glitters is not gold”

      Eickhardt-Dalbøge, S. R., Kragh, K. N., Schrøder, S., Poulsen, Steen Seier, Sillesen, Henrik, Givskov, Michael, Høiby, Niels, Bjarnsholt, Thomas & Alhede, M., 2015, In: Pathogens and Disease. 73, 4, 4 p., ftv012.

      Research output: Contribution to journal › Letter › Research › peer-review

    13. Published

      Prevention of biofilm formation in the soft tissue filler Aquamid

      Er, Ö., Kühl, Michael, Tvede, M., Høiby, Niels, Nielsen, A. K. & Bjarnsholt, Thomas, 2011.

      Research output: Contribution to conference › Poster › Research › peer-review

    14. Published

      PNA-based fluorescence in situ hybridization for identification of bacteria in clinical samples

      Fazli, M., Bjarnsholt, Thomas, Høiby, Niels, Givskov, Michael & Tolker-Nielsen, Tim, 2014, In: Methods in Molecular Biology. 1211, p. 261-71 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Phenotypic shift in Pseudomonas aeruginosa populations from cystic fibrosis lungs after 2-week antipseudomonal treatment

      Fernandez-Barat, L., Ciofu, Oana, Kragh, K. N., Pressler, T., Johansen, U., Motos, A., Torres, A. & Høiby, Niels, Mar 2017, In: Journal of Cystic Fibrosis. 16, 2, p. 222-229

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Biological Trojan horse: Antigen 43 provides specific bacterial uptake and survival in human neutrophils

      Fexby, S., Bjarnsholt, Thomas, Jensen, Peter Østrup, Roos, V., Høiby, Niels, Givskov, Michael & Klemm, P., 2006, In: Infection and Immunity. 75, 1, p. 30-4 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Typing of Pseudomonas aeruginosa strains in Norwegian cystic fibrosis patients.

      Fluge, G., Ojeniyi, B., Høiby, Niels, Digranes, A., Ciofu, Oana, Hunstad, E., Haanaes, O. C. & Storrøsten, O. T., 2001, In: Clinical Microbiology and Infection. 7, 5, p. 238-43 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

      Folkesson, A., Jelsbak, L., Yang, L., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels & Molin, S., Dec 2012, In: Nature Reviews. Microbiology. 10, 12, p. 841-851 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      A normally occurring staphylococcus antibody in human serum - Commentary

      Forsgren, A. & Høiby, Niels, 2007, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 115, 5, p. 540-541 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Effect of aerosolized rhDNase (Pulmozyme (R)) on pulmonary colonization in patients with cystic fibrosis

      Frederiksen, B., Pressler, T., Hansen, A., Koch, C. & Høiby, Niels, 2006, In: Acta Paediatrica. 95, 9, p. 1070-1074 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms

      Gade, P. A. V., Olsen, T. B., Jensen, Peter Østrup, Kolpen, Mette, Høiby, Niels, Henneberg, K. Å. & Sams, T., 2018, In: PLoS ONE. 13, 6, 16 p., e0198909.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis

      Garred, P., Pressler, T., Madsen, H. O., Frederiksen, B., Svejgaard, A., Høiby, Niels, Schwartz, M. & Koch, C., 1999, In: Journal of Clinical Investigation. 104, p. 431-437

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis

      Geisenberger, O., Givskov, Michael, Riedel, K., Høiby, Niels, Tümmler, B. & Eberl, L., 2000, In: F E M S Microbiology Letters. 184, 2, p. 273-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Production of N-acyl-L-homoserine lactones by Pseudomonas aeruginosa isolates from chronic lung infections associated with cystic fibrosis

      Geisenberger, O., Givskov, Michael, Riedel, K., Høiby, Niels, Tümmler, B. & Eberl, L., 2000, In: FEMS Microbiology Letters. 184, p. 273-278

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Induction of beta-lactamase production in Pseudomonas aeruginosa biofilm

      Giwercman, B., Jensen, E. T., Høiby, Niels, Kharazmi, A. & Costerton, J. W., 1991, In: Antimicrobial Agents and Chemotherapy. 35, 5, p. 1008-10 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Antibodies against chromosomal beta-lactamase.

      Giwercman, B., Rasmussen, J. W., Ciofu, Oana, Clemmentsen, I., Schumacher, H. & Høiby, Niels, 1994, In: Antimicrobial Agents and Chemotherapy. 38, 10, p. 2306-10 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Ventillation inhomogeneity correlates with airway colonization in patients with CF

      Green, K., Høiby, Niels, Gustafsson, P., Pressler, T. & Nielsen, K. G., 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    28. Published

      Towards diagnostic guidelines for biofilm-associated infections

      Hall-Stoodley, L., Stoodley, P., Kathju, S., Høiby, Niels, Moser, Claus Ernst, William Costerton, J., Moter, A. & Bjarnsholt, Thomas, Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 127-145 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Inflammation in Achromobacter xylosoxidans infected cystic fibrosis patients

      Hansen, C. R., Pressler, T., Nielsen, K. G., Jensen, Peter Østrup, Bjarnsholt, Thomas & Høiby, Niels, 1 Jan 2010, In: Journal of Cystic Fibrosis. 9, 1, p. 51-58 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Early aggressive eradication therapy for intermittent Pseudomonas aeruginosa airway colonization in cystic fibrosis patients: 15 years experience

      Hansen, C. R., Pressler, T. & Høiby, Niels, 2008, In: Journal of Cystic Fibrosis. 7, 6, p. 523-530 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Long-term, low-dose azithromycin treatment reduces the incidence but increases macrolide resistance in Staphylococcus aureus in Danish CF patients

      Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, H. K., 2008, In: Journal of Cystic Fibrosis. 8, 1, p. 58-62 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Survival of Achromobacter xylosoxidans infected CF patients is similar to survival found in Burkholderia multivorans infected CF patients

      Hansen, C. R., Pressler, T. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    33. Published

      Maintaining normal lung function in children with cystic fibrosis is possible with aggressive treatment regardless of Pseudomonas aeruginosa infections

      Hansen, C. R., Gilljam, M., Olesen, H. V., Høiby, Niels, Karpati, F., Johansson, E., Krantz, C., Skov, M., Pressler, T. & Lindblad, A., 2021, In: Acta Pædiatrica. 110, 9, p. 2607-2609 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

      Hansen, S. K., Rau, M. H., Johansen, Helle Krogh, Ciofu, Oana, Jelsbak, L., Yang, L., Folkesson, A., Jarmer, H. Ø., Aanæs, Kasper, von Buchwald, Christian, Høiby, Niels & Molin, S., 2012, In: I S M E Journal. 6, 1, p. 31-45

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies

      Hassett, D. J., Korfhagen, T. R., Irvin, R. T., Schurr, M. J., Sauer, K., Lau, G. W., Sutton, M. D., Yu, H. & Høiby, Niels, 1 Feb 2010, In: Expert Opinion On Therapeutic Targets. 14, 2, p. 117-30 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Hjertesygdomme

      Haunsø, S., Boesgaard, S., Bundsgaard, H., Bøtker, H. E., Carlsen, J., Clemmensen, P., Egeblad, H., Engstrøm, T., Grande, P., Hansen, H. S., Hassager, C., Høiby, N., Høilund-Carlsen, P. F., Kjeldsen, K., Køber, L., Larsen, M. L., Nordestgaard, B., Pedersen, A. K., Sigurd, B., Svendsen, J. H. & 2 others, Søndergaard, Lars & Sørensen, K., 2009, Medicinsk Kompendium. Schaffalitzky de Muckadell, O. B., Haunsø, S. & Vilstrup, H. (eds.). 17 ed. København: Nyt Nordisk Forlag Arnold Busck, p. 908-1216 309 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    37. Published

      Cellular responses of A549 alveolar epithelial cells to serially collected Pseudomonas aeruginosa from cystic fibrosis patients at different stages of pulmonary infection

      Hawdon, N. A., Aval, P. S., Barnes, R. J., Gravelle, S. K., Rosengren, J., Khan, S., Ciofu, Oana, Johansen, Helle Krogh, Høiby, Niels & Ulanova, M., 1 Jul 2010, In: FEMS Immunology and Medical Microbiology. 59, 2, p. 207-20 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: A European consensus

      Heijerman, H., Westerman, E., Conway, S., Touw, D., Döring, G., Høiby, Niels & consensus working group, C. W. G., 2009, In: Journal of Cystic Fibrosis. 8, 5, p. 295-315 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      High β-lactamase levels change the pharmacodynamics of β-lactam antibiotics in Pseudomonas aeruginosa biofilms

      Hengzhuang, W., Ciofu, Oana, Yang, L., Wu, H., Song, Z., Oliver, A. & Høiby, Niels, Jan 2013, In: Antimicrobial Agents and Chemotherapy. 57, 1, p. 196-204 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Optimization of colistin dosing regimen for cystic fibrosis patients with chronic Pseudomonas aeruginosa biofilm lung infections

      Hengzhuang, W., Green, K., Pressler, T., Skov, M., Katzenstein, T. L., Wu, X. & Høiby, Niels, 2019, In: Pediatric Pulmonology. 54, 5, p. 575-580

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Further Commentary

      Hengzhuang, W. & Høiby, Niels, 2020, In: Pediatric Pulmonology. 55, 1, 1 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    42. Published

      In vivo pharmacokinetics/pharmacodynamics of colistin and imipenem in Pseudomonas aeruginosa biofilm infection

      Hengzhuang, W., Wu, H., Ciofu, Oana, Song, Z. & Høiby, Niels, May 2012, In: Antimicrobial Agents and Chemotherapy. 56, 5, p. 2683-2690 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Pharmacokinetics and pharmacodynamics of antibiotics in biofilm infections of Pseudomonas aeruginosa in vitro and in vivo

      Hengzhuang, W., Høiby, Niels & Ciofu, Oana, 2014, In: Methods in molecular biology (Clifton, N.J.). 1147, p. 239-54 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Pharmacokinetics/pharmacodynamics of colistin and imipenem on mucoid and nonmucoid Pseudomonas aeruginosa biofilms

      Hengzhuang, W., Wu, H., Ciofu, Oana, Song, Z., Høiby, Niels & Wang, H., Sep 2011, In: Antimicrobial Agents and Chemotherapy. 55, 9, p. 4469-74 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Pharmacokinetics/Pharmacodynamics of Colistin and Imipenem on Mucoid and Nonmucoid Pseudomonas aeruginosa Biofilms

      Hengzhuang, W., Wu, H., Ciofu, Oana, Song, Z. & Høiby, Niels, 1 Sep 2011, In: Antimicrobial Agents and Chemotherapy. 55, 9, p. 4469-74 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      P. aeruginosa flow-cell biofilms are enhanced by repeated phage treatments but can be eradicated by phage-ciprofloxacin combination: —monitoring the phage–P. aeruginosa biofilms interactions

      Henriksen, K., Rørbo, N., Rybtke, Morten Levin, Martinet, M. G., Tolker-Nielsen, Tim, Høiby, Niels, Middelboe, Mathias & Ciofu, Oana, 2019, In: Pathogens and Disease. 77, 2, 11 p., ftz011.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound

      Hentzer, M., Riedel, K., Rasmussen, T. B., Heydorn, A., Andersen, Jens Bo, Parsek, M. R., Rice, S. A., Eberl, L., Molin, S., Høiby, Niels, Kjelleberg, S. & Givskov, Michael, 2002, In: Microbiology. 148, Pt 1, p. 87-102 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors

      Hentzer, M., Wu, H., Andersen, Jens Bo, Riedel, K., Rasmussen, T. B., Bagge, N., Kumar, N., Schembri, M. A., Song, Z., Kristoffersen, P., Manefield, M., Costerton, J. W., Molin, S., Eberl, L., Steinberg, P., Kjelleberg, S., Høiby, Niels & Givskov, Michael, 2003, In: EMBO Journal. 22, 15, p. 3803-15 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Små børn får hyppigt bihulebetaendelse

      Herløv-Nielsen, H. & Høiby, Niels, 29 Nov 2010, In: Ugeskrift for Laeger. 172, 48, p. 3320-5 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Colistin/Tobramycin combinations for killing of P. aeruginosa biofilms in cyxstic fibrosis- a pre-clinical and clinical in vivo study

      Herrmann, G., Wu, H., Song, Z., Wang, H., Høiby, Niels, Ulrich, M., Riethmöller, J. & Döring, G., 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

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