Niels Høiby

Niels Høiby

Professor, No job title

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    ORCID: 0000-0002-1347-725X

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    1. Published

      In vivo demonstration of Pseudomonas aeruginosa biofilms as independent pharmacological microcompartments

      Christophersen, L., Schwartz, F. A., Lerche, C. J., Svanekjær, T., Kragh, K. N., Laulund, A. S., Thomsen, K., Henneberg, K. Å., Sams, T., Høiby, Niels & Moser, Claus Ernst, 2020, In: Journal of Cystic Fibrosis. 19, 6, p. 996-1003

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      In vivo evolution of antimicrobial resistance in a biofilm model of Pseudomonas aeruginosa lung infection

      Higazy, Doaa Mohamed Mohamed E, Pham, A. D., van Hasselt, C., Høiby, Niels, Jelsbak, L., Moser, Claus Ernst & Ciofu, Oana, 2024, In: The ISME Journal. 18, 1

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      In vivo pharmacokinetics/pharmacodynamics of colistin and imipenem in Pseudomonas aeruginosa biofilm infection

      Hengzhuang, W., Wu, H., Ciofu, Oana, Song, Z. & Høiby, Niels, May 2012, In: Antimicrobial Agents and Chemotherapy. 56, 5, p. 2683-2690 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes

      Van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Phipps, R., Jensen, Peter Østrup, Christophersen, L., Pamp, S. J., Moser, C., Mikkelsen, P. J., Koh, A. Y., Tolker-Nielsen, Tim, Pier, G. B., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Jul 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 7, p. 537-46 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions

      Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Increased serum concentration of G-CSF in cystic fibrosis patients with chronic Pseudomonas aeruginosa pneumonia

      Jensen, Peter Østrup, Moser, Claus Ernst, Kharazmi, A., Presler, T., Koch, C. & Høiby, Niels, Aug 2006, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 5, 3, p. 145-51 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Increased severity of chronic Pseudomonas aeruginosa biofilm infection in the smaller airways of BALB/c mice

      Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    8. Published

      Increased severity of chronic Pseuomonas aeruginosa biofilm infection in the smaller airways of BALB/C mice

      Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 0 p.

      Research output: Contribution to conference › Poster › Research › peer-review

    9. Published

      Individual pharmacokinetic variation leads to underdosing of ciprofloxacin in some cystic fibrosis patients

      Schultz, A. N. Ø., Høiby, Niels, Nielsen, X. C., Pressler, T., Dalhoff, Kim, Duno, M., Buchard, Anders, Johansen, H. K., Wang, H. & Dalbøge, C. S., Mar 2017, In: Pediatric Pulmonology. 52, 3, p. 319-323 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Induction of beta-lactamase production in Pseudomonas aeruginosa biofilm

      Giwercman, B., Jensen, E. T., Høiby, Niels, Kharazmi, A. & Costerton, J. W., 1991, In: Antimicrobial Agents and Chemotherapy. 35, 5, p. 1008-10 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Induction of oxidative burst response in human neutrophils by immune complexes made in vitro of lipopolysaccharide and hyperimmune serum from chronically infected patients

      Kronborg, Gitte, Fomsgaard, A., Jensen, E. T., Kharazmi, A. & Høiby, Niels, 1993, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 101, 11, p. 887-94 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Infection control in cystic fibrosis: Practical recommendations for the hospital, clinic and social settings

      Saiman, L., MacDonald, N., Burns, J. L., Høiby, Niels, Speert, D. & Weber, D., 2000, In: American Journal of Infection Control. 28, p. 381-385

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Infektiøs endokardit

      Kjeldsen, K., Høiby, Niels, Egeblad, H., Muckadell, O. B. S. D., Haunsoe, S. & Vilstrup, H., 2009, Medicinsk Kompendium. 17th ed. København: Dansk Sygeplejeråd, p. 1047-1057 10 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    14. Published

      Inflammation in Achromobacter xylosoxidans infected cystic fibrosis patients

      Hansen, C. R., Pressler, T., Nielsen, K. G., Jensen, Peter Østrup, Bjarnsholt, Thomas & Høiby, Niels, 1 Jan 2010, In: Journal of Cystic Fibrosis. 9, 1, p. 51-58 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Influence of antidrug antibodies on plectasin efficacy and pharmacokinetics

      Brinch, K. S., Frimodt-Møller, N., Høiby, Niels & Kristensen, H., 2009, In: Antimicrobial Agents and Chemotherapy. 53, 11, p. 4794-800 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Influenza

      Høiby, Niels, 2010

      Research output: Other contribution › Net publication - Internet publication › Research

    17. Published

      Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: A European consensus

      Heijerman, H., Westerman, E., Conway, S., Touw, D., Döring, G., Høiby, Niels & consensus working group, C. W. G., 2009, In: Journal of Cystic Fibrosis. 8, 5, p. 295-315 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound

      Hentzer, M., Riedel, K., Rasmussen, T. B., Heydorn, A., Andersen, Jens Bo, Parsek, M. R., Rice, S. A., Eberl, L., Molin, S., Høiby, Niels, Kjelleberg, S. & Givskov, Michael, 2002, In: Microbiology. 148, Pt 1, p. 87-102 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo

      van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Qvortrup, Klaus, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Aug 2012, In: Infection and Immunity. 80, 8, p. 2601-2607 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control

      Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 2010, In: Expert Reviews in Molecular Medicine. 12, p. e11 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Interferon-gamma (IFN-gamma) treatment decreases the inflammatory response in chronic Pseudomonas aeruginosa pneumonia in rats

      Johansen, Helle Krogh, Hougen, H. P., Rygaard, J. & Høiby, Niels, 1996, In: Clinical and Experimental Immunology. 103, 2, p. 212-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin

      Brinch, K. S., Tulkens, P. M., Van Bambeke, F., Frimodt-Møller, N., Høiby, Niels & Kristensen, H., 1 Aug 2010, In: Journal of Antimicrobial Chemotherapy. 65, 8, p. 1720-4 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Intranasal immunisation with conjugate vaccine protects mice from systemic and respiratory tract infection with Pseudomonas aeruginosa

      Zuercher, A. W., Horn, M. P., Wu, H., Song, Z. J., Bundgaard, C. J., Johansen, Helle Krogh, Høiby, Niels, Marcus, P. & Lang, A. B., 2006, In: Vaccine. 24, 20, p. 4333-4342 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Investigation of the algT operon sequence in mucoid and non-mucoid Pseudomonas aeruginosa isolates from 115 Scandinavian patients with cystic fibrosis and in 88 in vitro non-mucoid revertants.

      Ciofu, Oana, Lee, B., Johannesson, M., Hermansen, N. O., Meyer, P., Høiby, Niels & Scandinavian Cystic Fibrosis Study Consortium, S. C. F. S. C., 2008, In: Microbiology. 154, Pt 1, p. 103-13 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Is repeated antibiotic prescription following treatment with sulfonamide or pivmecillinam a valid method for assessment of therapeutic failure in urinary infection?

      Høiby, Niels, 2003, In: Ugeskrift for læger. 165(45), p. 4316-4317

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Isolation measures for prevention of infection with respiratory pathogens in cystic fibrosis: a systematic review?

      Høiby, Niels & Johansen, Helle Krogh, 2007, In: Journal of Hospital Infection. 65, 4, p. 374-375 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Itraconazole treatment of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis

      Skov, M., Høiby, Niels & Koch, C., 2002, In: Allergy. European Journal of Allergy and Clinical Immunology. 57, p. 723-728

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Kai Adolf Jensen, professor i almindelig patologi

      Høiby, Niels, 2016, In: Bibliotek for Laeger. 208, 4, p. 344-361

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Kan man stole på urinmikroskopi og dyrkning, der er udført i almen praksis? Debatindlæg vedr. artikel af Bjerrum et al

      Høiby, Niels & Tvede, M., 2002, In: Ugeskrift for læger. 164, p. 2931-2932

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Kan miltbrand smitte fra patient til patient?

      Høiby, Niels, 2001, In: Ugeskrift for læger. 163, p. 6606-6607

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Kernikterus og sulfamethizolbehandling

      Høiby, Niels, 2006, In: Ugeskrift for læger. 168, 13, p. 1349-1350 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Kittelbogen medicin.dk

      Tvede, M. & Høiby, Niels, 2007, In: Ugeskrift for læger. 169, 35, p. 2904-

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Klinisk Mikrobiologi og Infektionsmedicin

      Høiby, Niels & Skinhøj, P., 2008, København: FADL's Forlag. 563 p.

      Research output: Book/Report › Book › Research › peer-review

    34. Published

      Klinisk bakteriologi, infektionshygiejne og antibiotikabehandling

      Johansen, H. K., Andersen, L. P., Skinhoj, P., Høiby, Niels & Johansen, Helle Krogh, 2008, Klinisk Mikrobiologi og Infektionsmedicin. 3rd ed. København: FADL's Forlag, Vol. 6. p. 223-298 75 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    35. Published

      Klinisk mikrobiologi og infektionsmedicin - almen del

      Høiby, Niels & Skinhøj, P., 2009, København: FADL's Forlag. 114 p.

      Research output: Book/Report › Book › Research › peer-review

    36. Published

      Kolera i Danmark--et importeret sygdomstilfoelde

      Lange, Kai, Pedersen, K. M., Nielsen, S. E. & Høiby, Niels, 17 Apr 1995, In: Ugeskrift for Laeger. 157, 16, p. 2325-6 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Korte træk af mikrobiologiens historie

      Høiby, Niels & Skinhøj, P., 2008, Klinisk Mikrobiologi og Infektionsmedicin. København: FADL's Forlag, Vol. 1. p. 1-4 3 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    38. Published

      Lack of the Major Multifunctional Catalase KatA in Pseudomonas aeruginosa Accelerates Evolution of Antibiotic Resistance in Ciprofloxacin-Treated Biofilms

      Ahmed, M. N., Porse, A., Abdelsamad, A., Sommer, M., Høiby, Niels & Ciofu, Oana, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 10, 12 p., e00766-19.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Lactoferricin-inspired peptide AMC-109 augments the effect of ciprofloxacin against Pseudomonas aeruginosa biofilm in chronic murine wounds

      Laulund, A. S., Schwartz, F. A., Christophersen, L., Høiby, Niels, Svendsen, J. S. M., Stensen, W., Thomsen, K., Cavanagh, J. P. & Moser, Claus Ernst, 2022, In: Journal of Global Antimicrobial Resistance. 29, p. 185-193 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Lipocalin 2 is protective against E. coli pneumonia

      Wu, H., Santoni-Rugiu, E., Ralfkiaer, E., Porse, Bo Torben, Moser, Claus Ernst, Høiby, Niels, Borregaard, N. & Cowland, J. B., 2010, In: Respiratory research. 11, p. 96

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Lipocalin 2 is protective against E. coli pneumonia

      Wu, H., Santoni Rugiu, Eric, Ralfkiaer, E., Porse, Bo Torben, Moser, C., Høiby, Niels, Borregaard, N., Cowland, J. B., Wu, H., Santoni Rugiu, Eric, Ralfkiær, E., Porse, B. T., Moser, C. E., Høiby, N., Borregaard, N. & Cowland, J., 15 Jun 2010, In: Respiratory research (Online). 11, 96, 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Listerias følsomhed for penicillin, ampicillin, piperacillin og meropenem. Hvad er den bedste behandling?

      Knudsen, J. D., Østergaard, C. & Høiby, Niels, 2002, In: Nyt om Mikrobiologi. 59, p. 6-9

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Long-term, low-dose azithromycin treatment reduces the incidence but increases macrolide resistance in Staphylococcus aureus in Danish CF patients

      Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, H. K., 2008, In: Journal of Cystic Fibrosis. 8, 1, p. 58-62 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Louis Pasteur and the birth of microbiology in Denmark

      Høiby, Niels, 2024, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 132, 1, p. 43-52

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Trøstrup, H., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Bundgaard, H., Høiby, Niels & Moser, C., 1 Dec 2015, In: European Journal of Clinical Microbiology & Infectious Diseases. 34, 12, p. 2349-2357 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Læger mistænkeliggøres på et tyndt grundlag

      Høiby, Niels, 29 Jan 2010, In: Dagens Medicin. 3, 29

      Research output: Contribution to journal › Comment/debate › Communication

    47. Published

      Lægevidenskabens og Pandoras æsker

      Høiby, Niels, 2002, Humaniora og sundhedsvidenskab. p. 98-118

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    48. Published

      Løgn og frygt i det syge hus

      Høiby, Niels, 2002, In: Ekstra Bladet. 25-10-2002, p. -

      Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication

    49. Published

      Maintaining normal lung function in children with cystic fibrosis is possible with aggressive treatment regardless of Pseudomonas aeruginosa infections

      Hansen, C. R., Gilljam, M., Olesen, H. V., Høiby, Niels, Karpati, F., Johansson, E., Krantz, C., Skov, M., Pressler, T. & Lindblad, A., 2021, In: Acta Pædiatrica. 110, 9, p. 2607-2609 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Mannan-binding lectin is a determinant of survival in infective endocarditis

      Tran, C. T., Kjeldsen, K. E., Haunsø, Stig, Høiby, Niels, Johansen, Helle Krogh & Christiansen, M., 2007, In: Clinical and Experimental Immunology. 148, 1, p. 101-105 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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