Oana Ciofu
Professor
Bacteriology
Blegdamsvej 3B, 2200 København N, 24 Bygning 24, Building: 24-1-10
Member of:
- 1994
- Published
Antibodies against chromosomal beta-lactamase.
Giwercman, B., Rasmussen, J. W., Ciofu, Oana, Clemmentsen, I., Schumacher, H. & Høiby, Niels, 1994, In: Antimicrobial Agents and Chemotherapy. 38, 10, p. 2306-10 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of antibiotic resistance in Pseudomonas aeruginosa during two decades of antipseudomonal treatment at the Danish CF Center.
Ciofu, Oana, Giwercman, B., Pedersen, S. S. & Høiby, Niels, 1994, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 102, 9, p. 674-80 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Antibodies against Pseudomonas aeruginosa chromosomal beta-lactamase inpatients with cystic fibrosis are markers of the development of resistance of P. aeruginosa to beta-lactams.
Ciofu, Oana, Giwercman, B., Walter-Rasmussen, J., Pressler, T., Pedersen, S. S. & Høiby, Niels, 1995, In: Journal of Antimicrobial Chemotherapy. 35, 2, p. 295-304 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
Meropenem in cystic fibrosis patients infected with resistant Pseudomonas aeruginosa or Burkholderia cepacia and with hypersensitivity to beta-lactam antibiotics.
Ciofu, Oana, Jensen, T., Pressler, T., Johansen, Helle Krogh, Bender Koch, Christian & Høiby, Niels, 1996, In: Clinical Microbiology and Infection. 2, 2, p. 91-98 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative analysis of the IgG and IgG subclass immune responses to chromosomal Pseudomonas aeruginosa beta-lactamase in serum from patients with cystic fibrosis by western blotting and laser scanning densitometry.
Petersen, T. D., Ciofu, Oana, Pressler, T., Giwercman, B., Pedersen, S. S. & Høiby, Niels, 1996, In: Thorax. 51, 7, p. 733-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of carbapenems and other antibiotics for pulmonary infections in patients with cystic fibrosis.
Høiby, Niels, Ciofu, Oana, Jensen, T., Pressler, T., Johansen, Helle Krogh & Koch, C., 1996, In: Pediatric Infectious Disease Journal. 15, 8, p. 738-43 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Pseudomonas aeruginosa isolates from patients with cystic fibrosis have different beta-lactamase expression phenotypes but are homogeneous in the ampC-ampR genetic region.
Campbell, J. I., Ciofu, Oana & Høiby, Niels, 1997, In: Antimicrobial Agents and Chemotherapy. 41, 6, p. 1380-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The clonal antibody response to Pseudomonas aeruginosa heat shock protein is highly diverse in cystic fibrosis patients.
Ulanova, M., Petersen, T. D., Ciofu, Oana, Jensen, P., Hahn-Zoric, M., Hanson, L. A. & Høiby, Niels, 1997, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 105, 6, p. 449-56 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of allotypes on the IgG subclass response to chromosomal beta-lactamase of Pseudomonas aeruginosa in cystic fibrosis patients.
Ciofu, Oana, Pressler, T., Pandey, J. P. & Høiby, Niels, 1997, In: Clinical and Experimental Immunology. 108, 1, p. 88-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Avidity of anti-P aeruginosa antibodies during chronic infection in patients with cystic fibrosis.
Ciofu, Oana, Petersen, T. D., Jensen, P. & Høiby, Niels, 1999, In: Thorax. 54, 2, p. 141-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.
Mathee, K., Ciofu, Oana, Sternberg, C., Lindum, P. W., Campbell, J. I., Jensen, P., Johnsen, A. H., Givskov, Michael, Ohman, D. E., Molin, S., Høiby, Niels & Kharazmi, A., 1999, In: Microbiology. 145 ( Pt 6), p. 1349-57 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Chromosomal beta-lactamase is packaged into membrane vesicles and secreted from Pseudomonas aeruginosa.
Ciofu, Oana, Beveridge, T. J., Kadurugamuwa, J., Walther-Rasmussen, J. & Høiby, Niels, 2000, In: Journal of Antimicrobial Chemotherapy. 45, 1, p. 9-13 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.
Jalal, S., Ciofu, Oana, Høiby, Niels, Gotoh, N. & Wretlind, B., 2000, In: Antimicrobial Agents and Chemotherapy. 44, 3, p. 710-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid development in vitro and in vivo of resistance to ceftazidime in biofilm-growing Pseudomonas aeruginosa due to chromosomal beta-lactamase
Bagge, N., Ciofu, Oana, Skovgaard, Lene Theil & Høiby, Niels, Sep 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 9, p. 589-600 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Characterization of paired mucoid/non-mucoid Pseudomonas aeruginosa isolates from Danish cystic fibrosis patients: antibiotic resistance, beta-lactamase activity and RiboPrinting.
Ciofu, Oana, Fussing, V., Bagge, N., Koch, C. & Høiby, Niels, 2001, In: Journal of Antimicrobial Chemotherapy. 48, 3, p. 391-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth.
Høiby, Niels, Johansen, Helle Krogh, Moser, C., Song, Z., Ciofu, Oana & Kharazmi, A., 2001, In: Microbes and Infection. 3, 1, p. 23-35 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Typing of Pseudomonas aeruginosa strains in Norwegian cystic fibrosis patients.
Fluge, G., Ojeniyi, B., Høiby, Niels, Digranes, A., Ciofu, Oana, Hunstad, E., Haanaes, O. C. & Storrøsten, O. T., 2001, In: Clinical Microbiology and Infection. 7, 5, p. 238-43 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Antibodies against beta-lactamase can improve ceftazidime treatment of lung infection with beta-lactam-resistant Pseudomonas aeruginosa in a rat model of chronic lung infection.
Ciofu, Oana, Bagge, N. & Høiby, Niels, 2002, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 110, 12, p. 881-91 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD.
Bagge, N., Ciofu, Oana, Hentzer, M., Campbell, J. I. A., Givskov, Michael & Høiby, Niels, 2002, In: Antimicrobial Agents and Chemotherapy. 46, 11, p. 3406-11 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Pseudomonas aeruginosa alginate is refractory to Th1 immune response and impedes host immune clearance in a mouse model of acute lung infection.
Song, Z., Wu, H., Ciofu, Oana, Kong, K., Høiby, Niels, Rygaard, J., Kharazmi, A. & Mathee, K., 2003, In: Journal of Medical Microbiology. 52, Pt 9, p. 731-40 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa chromosomal beta-lactamase in patients with cystic fibrosis and chronic lung infection. Mechanism of antibiotic resistance and target of the humoral immune response.
Ciofu, Oana, 2003, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 116, p. 1-47 46 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Dynamics and spatial distribution of beta-lactamase expression in Pseudomonas aeruginosa biofilms.
Bagge, N., Hentzer, M., Andersen, Jens Bo, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1168-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production.
Bagge, N., Schuster, M., Hentzer, M., Ciofu, Oana, Givskov, Michael, Greenberg, E. P. & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1175-87 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Heterogeneity of biofilms formed by nonmucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis.
Lee, B., Haagensen, J. A. J., Ciofu, Oana, Andersen, Jens Bo, Høiby, Niels & Molin, S., 2005, In: Journal of Clinical Microbiology. 43, 10, p. 5247-55 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunisation in the current management of cystic fibrosis patients.
Malfroot, A., Adam, G., Ciofu, Oana, Döring, G., Knoop, C., Lang, A. B., Van Damme, P., Dab, I., Bush, A. & European Cystic Fibrosis Society (ECFS) Vaccination Group, E. C. F. S. (. V. G., 2005, In: Journal of Cystic Fibrosis. 4, 2, p. 77-87 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis
Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, 2005, In: Infection and Immunity. 73, 4, p. 2504-14 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Occurrence of hypermutable Pseudomonas aeruginosa in cystic fibrosis patients is associated with the oxidative stress caused by chronic lung inflammation.
Ciofu, Oana, Riis, B., Pressler, T., Poulsen, Henrik Enghusen & Høiby, Niels, 2005, In: Antimicrobial Agents and Chemotherapy. 49, 6, p. 2276-82 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum: Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis (Infection and Immunity (2005) 73, 4 (2504-2514))
Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, Aug 2005, In: Infection and Immunity. 73, 8, p. 5290 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2007
- Published
Cystic fibrosis: coping with resistance
Ciofu, Oana, Høiby, Niels, Gould, I. M. & Meer, J. W. M. V. D., 2007, Antibiotic policies: fighting resistance. Springer, p. 149-174 25 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.
Høiby, Niels, Johansen, Helle Krogh, Ciofu, Oana, Jensen, Peter Østrup, Bjarnsholt, Thomas & Givskov, Michael, 2007, In: Ugeskrift for læger. 169, 48, p. 4163-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients.
Jelsbak, L., Johansen, Helle Krogh, Frost, A., Thøgersen, R., Thomsen, Line Elnif, Ciofu, Oana, Yang, L., Haagensen, J. A. J., Høiby, Niels & Molin, S., 2007, In: Infection and Immunity. 75, 5, p. 2214-24 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
A master of adaptation and survival strategies
Høiby, Niels, Johansen, H. K., Moser, C., Ciofu, Oana & Rehm, B. H. A., 2008, Pseudomonas. Model Organism, Pathogen, Cell Factory. Weinheim: Wiley-VCH, Vol. 2. p. 25-44 19 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Generel bakteriologi
Høiby, Niels, Ciofu, Oana, Johansen, H. K., Andersen, L. P. & Skinhøj, P., 2008, Klinisk Mikrobiologi og Infektionsmedicin. 3rd ed. København: FADL's Forlag, Vol. 4. p. 21-107 86 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Investigation of the algT operon sequence in mucoid and non-mucoid Pseudomonas aeruginosa isolates from 115 Scandinavian patients with cystic fibrosis and in 88 in vitro non-mucoid revertants.
Ciofu, Oana, Lee, B., Johannesson, M., Hermansen, N. O., Meyer, P., Høiby, Niels & Scandinavian Cystic Fibrosis Study Consortium, S. C. F. S. C., 2008, In: Microbiology. 154, Pt 1, p. 103-13 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maximum Likelihood based comparison of the specific growth rates for P. aeruginosa and four mutator strains.
Philipsen, K. R., Christiansen, L. E., Mandsberg, L. F., Ciofu, Oana & Madsen, H., 2008, In: Journal of Microbiological Methods. 75, 3, p. 551-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients.
Johansen, Helle Krogh, Moskowitz, S. M., Ciofu, Oana, Pressler, T. & Høiby, Niels, 2008, In: Journal of Cystic Fibrosis. 7, 5, p. 391-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Chromosomal mechanisms of aminoglycoside resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients
Islam, S., Oh, H., Jalal, S., Karpati, F., Ciofu, Oana, Høiby, Niels & Wretlind, B., 2009, In: Clinical Microbiology and Infection. 15, 1, p. 60-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel experimental Pseudomonas aeruginosa infection model mimicking long-term host-pathogen interactions in cystic fibrosis.
Moser, Claus Ernst, van Gennip, M., Bjarnsholt, Thomas, Jensen, P. Ø., Lee, B., Hougen, H. P., Calum, Henrik Pierre, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2009, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 117, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Respiratory syncytial virus infection facilitates acute colonization of Pseudomonas aeruginosa in mice
de Vrankrijker, A. M. M., Wolfs, T. F. W., Ciofu, Oana, Høiby, Niels, van der Ent, C. K., Poulsen, Steen Seier & Johansen, Helle Krogh, 2009, In: Journal of Medical Virology. 81, 12, p. 2096-103 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustainable plant production in a changing world - a cross Faculty research network at KU
Strandmark, L. B., Schjoerring, Jan K., Christensen, Søren, Nybroe, O., Pedersen, J. G. T., Eilenberg, Jørgen, Munk, Lisa, Rønn, Regin, Ciofu, Oana, Bruun, Sander & Ørum, Jens Erik, 2009.Research output: Contribution to conference › Poster › Research
- Published
Sustainable plant production in a changing world - formation of a cross-faculty network
Strandmark, L. B., Schjoerring, Jan K., Christensen, Søren, Nybroe, O., Torp, J., Eilenberg, Jørgen, Munk, Lisa, Rønn, Regin, Ciofu, Oana, Bruun, Sander & Ørum, Jens Erik, 2009, In: IOP Conference Series: Earth and Environmental Science. 6, Session 34, 2 p., 342014.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis
Moser, C., Gennip, M. V., Bjarnsholt, Thomas, Jensen, Peter Østrup, Lee, B., Hougen, H. P., Calum, H., Ciofu, Oana, Givskov, Michael, Molin, S. & Høiby, Niels, 1 Feb 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 2, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system
Mandsberg, L. F., Ciofu, Oana, Kirkby, N., Christiansen, L. E., Poulsen, Henrik Enghusen, Høiby, Niels, Mandsberg, L. F., Ciofu, O., Kirkby, N., Christiansen, L. E., Poulsen, Henrik Enghusen & Høiby, N., 1 Jun 2009, In: Antimicrobial Agents and Chemotherapy. 53, 6, p. 2483-91 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa
van Gennip, M., Moser, C., Hultqvist, Louise Dahl, Bjarnsholt, Thomas, Calum, H., Jensen, Peter Østrup, Christophersen, L., Hougen, H. P., Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Dec 2009, In: Journal of Antimicrobial Chemotherapy. 64, 6, p. 1241-50 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Antibiotic resistance of bacterial biofilms
Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael, Molin, S. & Ciofu, Oana, 2010, In: International Journal of Antimicrobial Agents. 35, 4, p. 322-332 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Antibiotic tolerance and resistance in biofilms.
Ciofu, Oana & Tolker-Nielsen, Tim, 2010, Biofilm Infections. Bjarnsholt, T., Moser, C., Jensen, P. Ø. & Høiby, N. (eds.). New York, USA: Springer Publishing Company, p. 215-230 16 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Genetic adaptation of Pseudomonas aeruginosa during chronic lung infection of patients with cystic fibrosis: strong and weak mutators with heterogeneous genetic backgrounds emerge in mucA and/or lasR mutants
Ciofu, Oana, Mandsberg, L. F., Bjarnsholt, Thomas, Wassermann, T. & Høiby, Niels, 2010, In: Microbiology. 156, p. 1108-1119 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis
Kolpen, Mette, Hansen, C. R., Bjarnsholt, Thomas, Moser, C., Hultqvist, Louise Dahl, van Gennip, M., Ciofu, Oana, Mandsberg, L., Kharazmi, A., Döring, G., Givskov, Michael, Høiby, Niels & Jensen, Peter Østrup, 1 Jan 2010, In: Thorax. 65, 1, p. 57-62 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients
Bjarnsholt, Thomas, Jensen, Peter Østrup, Jakobsen, Tim Holm, Phipps, R., Nielsen, A. K., Rybtke, Morten Levin, Tolker-Nielsen, Tim, Givskov, Michael, Høiby, Niels, Ciofu, Oana & Scandinavian Cystic Fibrosis Study Consortium, S. C. F. S. C., 1 Jan 2010, In: PLoS ONE. 5, 4, p. e10115Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular responses of A549 alveolar epithelial cells to serially collected Pseudomonas aeruginosa from cystic fibrosis patients at different stages of pulmonary infection
Hawdon, N. A., Aval, P. S., Barnes, R. J., Gravelle, S. K., Rosengren, J., Khan, S., Ciofu, Oana, Johansen, Helle Krogh, Høiby, Niels & Ulanova, M., 1 Jul 2010, In: FEMS Immunology and Medical Microbiology. 59, 2, p. 207-20 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
Research output: Contribution to journal › Journal article › Research › peer-review
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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Effect of long-term voluntary exercise wheel running on susceptibility to bacterial pulmonary infections in a mouse model
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