Peter Østrup Jensen
Associate Professor
Bacteriology
Blegdamsvej 3B, 2200 København N, 24 Bygning 24, Building: 24-1-14
Member of:
- Published
Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis
Aanæs, Kasper, Rickelt, L. F., Johansen, Helle Krogh, von Buchwald, Christian, Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2011, In: Journal of Cystic Fibrosis. 10, 2, p. 114-120 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism
Adams, Yvonne, Clausen, Anne Skovsbo, Jensen, Peter Østrup, Lager, M., Wilhelmsson, P., Henningson, A. J., Lindgren, P. E., Faurholt-Jepsen, D., Mens, H., Kraiczy, P., Kragh, K. N., Bjarnsholt, Thomas, Kjær, Andreas, Lebech, Anne-Mette & Jensen, Anja Ramstedt, 2023, In: iScience. 26, 1, 105838.Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes
Alhede, M., Lorenz, M., Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, H. C., Bay, Lene & Bjarnsholt, Thomas, 2020, In: Medical Microbiology and Immunology. 209, p. 669–680Research output: Contribution to journal › Journal article › Research › peer-review
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The origin of extracellular DNA in bacterial biofilm infections in vivo
Alhede, M., Alhede, M., Qvortrup, Klaus, Kragh, K. N., Jensen, Peter Østrup, Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Pathogens and Disease. ftaa018.Research output: Contribution to journal › Journal article › Research › peer-review
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Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm
Alhede, M., Kragh, K. N., Qvortrup, Klaus, Allesen-Holm, M., van Gennip, M., Hultqvist, Louise Dahl, Jensen, Peter Østrup, Nielsen, A. K., Parsek, M., Wozniak, D., Molin, S., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2011, In: P L o S One. 6, 11, p. e27943Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes
Alhede, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Phipps, R. K., Moser, Claus Ernst, Christophersen, L., Hultqvist, Louise Dahl, van Gennip, M., Parsek, M., Høiby, Niels, Rasmussen, T. B. & Givskov, Michael, 2009, In: Microbiology. 155, 11, p. 3500-3508 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human immune cell mobilization during exercise: effect of IL-6 receptor blockade
Bay, M. L., Heywood, S., Wedell-Neergaard, A. S., Schauer, T., Lehrskov, L. L., Christensen, R. H., Legård, G. E., Jensen, Peter Østrup, Krogh-Madsen, Rikke & Ellingsgaard, H., 2020, In: Experimental Physiology. 105, 12, p. 2086-2098 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lactate in cystic fibrosis sputum
Bensel, T., Stotz, M., Borneff-Lipp, M., Wollschläger, B., Wienke, A., Taccetti, G., Campana, S., Meyer, K. C., Jensen, Peter Østrup, Lechner, U., Ulrich, M., Döring, G. & Worlitzsch, D., 2011, In: Journal of Cystic Fibrosis. 10, 1, p. 37-44 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect
Bjarnsholt, Thomas, van Gennip, M., Jakobsen, Tim Holm, Hultqvist, Louise Dahl, Jensen, Peter Østrup & Givskov, Michael, 2010, In: Nature Protocols (Print Edition). 5, 2, p. 282-93 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients
Bjarnsholt, Thomas, Jensen, Peter Østrup, Jakobsen, Tim Holm, Phipps, R., Nielsen, A. K., Rybtke, Morten Levin, Tolker-Nielsen, Tim, Givskov, Michael, Høiby, Niels, Ciofu, Oana & Scandinavian Cystic Fibrosis Study Consortium, S. C. F. S. C., 1 Jan 2010, In: PLoS ONE. 5, 4, p. e10115Research output: Contribution to journal › Journal article › Research › peer-review
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Why chronic wounds will not heal: a novel hypothesis
Bjarnsholt, Thomas, Kirketerp-Møller, K., Jensen, Peter Østrup, Madsen, K. G., Phipps, R. K., Krogfelt, K., Høiby, Niels & Givskov, Michael, 2008, In: Wound Repair and Regeneration. 16, 1, p. 2-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent
Bjarnsholt, Thomas, Jensen, Peter Østrup, Burmølle, Mette, Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, Claus Ernst, Molin, S., Høiby, Niels & Givskov, Michael, Feb 2005, In: Microbiology. 151, Pt 2, p. 373-83 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Silver against Pseudomonas aeruginosa biofilms
Bjarnsholt, Thomas, Kirketerp-Møller, K., Kristiansen, S., Phipps, R., Nielsen, A. K., Jensen, Peter Østrup, Høiby, Niels & Givskov, Michael, 2007, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 115, 8, p. 921-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The importance of understanding the infectious microenvironment
Bjarnsholt, Thomas, Whiteley, M., Rumbaugh, K. P., Stewart, P. S., Jensen, Peter Østrup & Frimodt-Møller, N., 2022, In: The Lancet Infectious Diseases. 22, 3, p. e88-e92Research output: Contribution to journal › Review › Research › peer-review
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The in vivo biofilm
Bjarnsholt, Thomas, Alhede, M., Alhede, M., Eickhardt-Sørensen, S. R., Moser, Claus Ernst, Kühl, Michael, Jensen, Peter Østrup & Høiby, Niels, 2013, In: Trends in Microbiology. 21, 9, p. 466-474 9 p.Research output: Contribution to journal › Review › Research › peer-review
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Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction
Bjarnsholt, Thomas, Jensen, Peter Østrup & Alhede, M., 2019, In: Pathogens and Disease. 77, 5, ftz052.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibiofilm Properties of Acetic Acid
Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients
Bjarnsholt, Thomas, Jensen, Peter Østrup, Fiandaca, M. J., Pedersen, J., Hansen, C. R., Andersen, C. B., Pressler, T., Givskov, Michael & Høiby, Niels, 1 Jun 2009, In: Pediatric Pulmonology. 44, 6, p. 547-58 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple roles of Pseudomonas aeruginosa TBCF10839 PilY1 in motility, transport and infection
Bohn, Y. T., Brandes, G., Rakhimova, E., Horatzek, S., Salunkhe, P., Munder, A., van Barneveld, A., Jordan, D., Bredenbruch, F., Häussler, S., Riedel, K., Eberl, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, C., Høiby, Niels, Tümmler, B. & Wiehlmann, L., 2008, In: Molecular Microbiology. 71, 3, p. 730-47 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bactericidal effect of colistin on planktonic Pseudomonas aeruginosa is independent of hydroxyl radical formation
Brochmann, R. P., Toft, A., Ciofu, Oana, Briales, A., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, 2014, In: International Journal of Antimicrobial Agents. 43, 2, p. 140-147 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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S-phase induction by interleukin-6 followed by chemotherapy in patients with chronic lymphocytic leukemia and non-Hodgkin's lymphoma
Brown, Peter de Nully, Diamant, M., Jensen, Peter Østrup, Geisler, C. H., Mortensen, B. T. & Nissen, N. I., Jul 1999, In: Leukemia and Lymphoma. 34, 3-4, p. 325-33 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections
Burmølle, Mette, Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, Preben, Tvede, M., Nyvad, B., Tolker-Nielsen, Tim, Givskov, Michael, Moser, Claus Ernst, Kirketerp-Møller, K., Johansen, Helle Krogh, Høiby, Niels, Jensen, Peter Østrup, Sørensen, Søren Johannes & Bjarnsholt, Thomas, 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.Research output: Contribution to journal › Review › Research › peer-review
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Cytokine and surface receptor diversity of NK cells in resistant C3H/HeN and susceptible BALB/c mice with chronic Pseudomonas aeruginosa lung infection
Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Shirai, R. & Høiby, Niels, Sep 2003, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 111, 9, p. 891-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Thermal injury induces impaired function in polymorphonuclear neutrophil granulocytes and reduced control of burn wound infection
Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Christoffersen, L., Damlund, D. S. M., Alhede, M., Bjarnsholt, Thomas, Hougen, H. P., Givskov, Michael, Jacobsen, G. K. & Høiby, Niels, 2008, In: Clinical and Experimental Immunology. 156, 1, p. 102-110 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology
Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653Research output: Contribution to journal › Journal article › Research › peer-review
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Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model
Cao, B., Christophersen, L., Thomsen, K., Sønderholm, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2015, In: The Journal of antimicrobial chemotherapy. 70, 7, p. 2057-2063 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Diffusion retardation by binding of tobramycin in an alginate biofilm model
Cao, B., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Sneppen, Kim, Høiby, Niels, Moser, Claus Ernst & Sams, T., 21 Apr 2016, In: P L o S One. 11, 4, 11 p., e0153616.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model
Cavanagh, J. P., Granslo, H. N., Fredheim, E. A., Christophersen, L., Jensen, Peter Østrup, Thomsen, K., van Gennip, M., Klingenberg, C., Flaegstad, T., Moser, Claus Ernst & Alhede, M., Sep 2013, In: The Journal of antimicrobial chemotherapy. 68, 9, p. 2106-10 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms
Chiang, W., Nilsson, M., Jensen, Peter Østrup, Høiby, Niels, Nielsen, T., Givskov, Michael & Tolker-Nielsen, Tim, May 2013, In: Antimicrobial Agents and Chemotherapy. 57, 5, p. 2352-61 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model
Hultqvist, Louise Dahl, Moser, C., Jensen, Peter Østrup, Rasmussen, T. B., Christophersen, L., Kjelleberg, S., Kumar, N., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2007, In: Microbiology. 153, Pt 7, p. 2312-20 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bead-size directed distribution of Pseudomonas aeruginosa results in distinct inflammatory response in a mouse model of chronic lung infection
Christophersen, L. J., Trøstrup, H., Damlund, D. S. M., Bjarnsholt, Thomas, Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, 2012, In: Experimental and clinical endocrinology. 170, 2, p. 222-30 10 p., 170.Research output: Contribution to journal › Journal article › Research › peer-review
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Tolerance and resistance of microbial biofilms
Ciofu, Oana, Moser, Claus Ernst, Jensen, Peter Østrup & Høiby, Niels, 2022, In: Nature Reviews Microbiology. 20, p. 621–635Research output: Contribution to journal › Review › Research › peer-review
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Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients
Ciofu, Oana, Tolker-Nielsen, Tim, Jensen, Peter Østrup, Wang, H. & Høiby, Niels, 2015, In: Advanced Drug Delivery Reviews. 85, p. 7-23 17 p.Research output: Contribution to journal › Review › Research › peer-review
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64Cu-DOTATATE positron emission tomography (PET) of borrelia burgdorferi infection: In vivo imaging of macrophages in experimental model of lyme arthritis
Clausen, Anne Skovsbo, Ørbæk, M., Pedersen, Regitze Renee, Jensen, Peter Østrup, Lebech, Anne-Mette & Kjær, Andreas, 2020, In: Diagnostics. 10, 10, 11 p., 790.Research output: Contribution to journal › Journal article › Research › peer-review
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Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms
Crabbé, A., Jensen, Peter Østrup, Bjarnsholt, Thomas & Coenye, T., 2019, In: Trends in Microbiology. 27, 10, p. 850-863Research output: Contribution to journal › Review › Research › peer-review
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Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase
Damgaard, D., Bjørn, M. E., Jensen, Peter Østrup & Nielsen, Claus Henrik, Dec 2017, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 1203-1208 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activation of pulmonary and lymph node dendritic cells during chronic Pseudomonas aeruginosa lung infection in mice
Damlund, D. S. M., Christophersen, L., Jensen, Peter Østrup, Alhede, M., Høiby, Niels & Moser, Claus Ernst, Jun 2016, In: APMIS - Journal of Pathology, Microbiology and Immunology. 124, 6, p. 500-507 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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B-cell cytokine responses to Porphyromonas gingivalis in patients with periodontitis and healthy controls
Danielsen, Anne Katrine, Damgaard, Christian, Massarenti, Laura, Jensen, Peter Østrup, Hansen, Peter Riis, Holmstrup, Palle & Nielsen, Claus Henrik, 2023, In: Journal of Periodontology. 94, 8, p. 997-1007 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ADDITION OF GLUCOSE PROVIDES MYCOBACTERIUM ABSCESSUS BIOFILM WITH PROTECTION AGAINST AMIKACIN
Demant, M., Kristensen, S., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup & Kolpen, M., 2019, In: Pediatric Pulmonology. 54, S2, p. S298-S299Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Catalase protects biofilm of Staphylococcus aureus against daptomycin activity
El Haj, C., Lichtenberg, Mads, Nielsen, K. L., Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: Antibiotics. 10, 5, 511.Research output: Contribution to journal › Journal article › Research › peer-review
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Biological Trojan horse: Antigen 43 provides specific bacterial uptake and survival in human neutrophils
Fexby, S., Bjarnsholt, Thomas, Jensen, Peter Østrup, Roos, V., Høiby, Niels, Givskov, Michael & Klemm, P., 2006, In: Infection and Immunity. 75, 1, p. 30-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The inflamed sputum in lower respiratory tract infection: l-lactate levels are correlated to neutrophil accumulation
Fredman, G., Kolpen, Mette, Hertz, F. B., Petersen, P. T., Jensen, A. V., Baunbæk-Egelund, G., Ravn, Pernille, Jensen, Peter Østrup & Faurholt-Jepsen, Daniel, 2019, In: APMIS. 127, 2, p. 72-79Research output: Contribution to journal › Journal article › Research › peer-review
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Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms
Gade, P. A. V., Olsen, T. B., Jensen, Peter Østrup, Kolpen, Mette, Høiby, Niels, Henneberg, K. Å. & Sams, T., 2018, In: PLoS ONE. 13, 6, 16 p., e0198909.Research output: Contribution to journal › Journal article › Research › peer-review
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Use of Oxygen Therapies in Wound Healing: Focus on Topical and Hyperbaric Oxygen Treatment
Gottrup, F., Dissemond, J., Baines, C., Frykberg, R., Jensen, Peter Østrup, Kot, J., Kröger, K. & Longobardi, P., 1 May 2017, In: Journal of Wound Care. 26, Sup5, p. S1-S43Research output: Contribution to journal › Journal article › Research › peer-review
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Inflammation in Achromobacter xylosoxidans infected cystic fibrosis patients
Hansen, C. R., Pressler, T., Nielsen, K. G., Jensen, Peter Østrup, Bjarnsholt, Thomas & Høiby, Niels, 1 Jan 2010, In: Journal of Cystic Fibrosis. 9, 1, p. 51-58 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Soluble ICAM-1 is modulated by hyperbaric oxygen treatment and correlates with disease severity and mortality in patients with necrotizing soft-tissue infection
Hedetoft, M., Moser, Claus Ernst, Jensen, Peter Østrup, Vinkel, J. & Hyldegaard, Ole, 2021, In: Journal of Applied Physiology. 130, 3, p. 729-736 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperbaric oxygen treatment impacts oxidative stress markers in patients with necrotizing soft-tissue infection
Hedetoft, M., Jensen, Peter Østrup, Moser, Claus Ernst, Vinkel, J. & Hyldegaard, Ole, 2021, In: Journal of Investigative Medicine. 69, 7, p. 1330-1338Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum avoids change in erythrocytic surface expression of phagocytosis markers during inhibition of nitric oxide synthase activity
Hempel, C., Kohnke, H., Maretty, L., Jensen, Peter Østrup, Staalsø, Trine & Kurtzhals, Jørgen, Nov 2014, In: Molecular and Biochemical Parasitology. 198, 1, p. 29-36 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Erratum: Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis (Infection and Immunity (2005) 73, 4 (2504-2514))
Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, Aug 2005, In: Infection and Immunity. 73, 8, p. 5290 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis
Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, 2005, In: Infection and Immunity. 73, 4, p. 2504-14 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 20166228
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
Research output: Contribution to journal › Journal article › Research › peer-review
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