Peter Østrup Jensen
Associate Professor
Bacteriology
Blegdamsvej 3B, 2200 København N, 24 Bygning 24, Building: 24-1-14
Member of:
- 2024
- E-pub ahead of print
Bacterial aerobic respiration is a major consumer of oxygen in sputum from patients with acute lower respiratory tract infection
Jensen, Peter Østrup, Olsen, P., Dungu, A. M., Egelund, G. B., Jensen, A. V., Ravn, P., Lindegaard, Birgitte, Hertz, Frederik Boëtius, Bjarnsholt, Thomas, Faurholt-Jepsen, D. & Kolpen, Mette, 2024, (E-pub ahead of print) In: APMIS.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism
Adams, Yvonne, Clausen, Anne Skovsbo, Jensen, Peter Østrup, Lager, M., Wilhelmsson, P., Henningson, A. J., Lindgren, P. E., Faurholt-Jepsen, D., Mens, H., Kraiczy, P., Kragh, K. N., Bjarnsholt, Thomas, Kjær, Andreas, Lebech, Anne-Mette & Jensen, Anja Ramstedt, 2023, In: iScience. 26, 1, 105838.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
B-cell cytokine responses to Porphyromonas gingivalis in patients with periodontitis and healthy controls
Danielsen, Anne Katrine, Damgaard, Christian, Massarenti, Laura, Jensen, Peter Østrup, Hansen, Peter Riis, Holmstrup, Palle & Nielsen, Claus Henrik, 2023, In: Journal of Periodontology. 94, 8, p. 997-1007 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
“The standard procedure” for Investigation of Oral Neutrophils in Oral Diseases
Jensen, Peter Østrup, Rikvold, P. D., Larsen, Kristine Røn, Jørgensen, Mette Rose & Kragelund, C., 2023, In: International Journal of Dentistry. 2023, 6 p., 1308326.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antimicrobial resistance of Pseudomonas aeruginosa in a cystic fibrosis population after introduction of a novel cephalosporin/β-lactamase inhibitor combination
Katzenstein, T. L., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup, Pressler, T., Johansen, Helle Krogh & Kolpen, Mette, 2023, In: APMIS. 131, 8, p. 419-425Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperbaric oxygen therapy augments ciprofloxacin effect against Pseudomonas aeruginosa biofilm infected chronic wounds in a mouse model
Laulund, A. S., Schwartz, F. A., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Calum, Henrik Pierre, Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 5, 100100.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
The importance of understanding the infectious microenvironment
Bjarnsholt, Thomas, Whiteley, M., Rumbaugh, K. P., Stewart, P. S., Jensen, Peter Østrup & Frimodt-Møller, N., 2022, In: The Lancet Infectious Diseases. 22, 3, p. e88-e92Research output: Contribution to journal › Review › Research › peer-review
- Published
Tolerance and resistance of microbial biofilms
Ciofu, Oana, Moser, Claus Ernst, Jensen, Peter Østrup & Høiby, Niels, 2022, In: Nature Reviews Microbiology. 20, p. 621–635Research output: Contribution to journal › Review › Research › peer-review
- Published
Increased sputum lactate during oral glucose tolerance test in cystic fibrosis
Jensen, Peter Østrup, Nielsen, B. U., Kolpen, Mette, Pressler, T., Faurholt-Jepsen, D. & Mathiesen, I. H. M., 2022, In: APMIS. 130, 8, p. 535-539Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial biofilms predominate in both acute and chronic human lung infections
Kolpen, Mette, Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, P., Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: European Respiratory Journal. Supplement. 60, Suppl. 66, 4.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial biofilms predominate in both acute and chronic human lung infections
Kolpen, M., Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, Pernille, Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: Thorax. 77, p. 1015–1022Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endotracheal lactate reflects lower respiratory tract infections and inflammation in intubated patients
Kolpen, M., Dalby Sørensen, C., Faurholt-Jepsen, D., Hertz, Frederik Boëtius, Jensen, Peter Østrup & Bestle, Morten Heiberg, 2022, In: APMIS. 130, 8, p. 507-514Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence of biofilms in acute infections challenges a longstanding paradigm
Kolpen, M., Jensen, Peter Østrup, Faurholt-Jepsen, D. & Bjarnsholt, Thomas, 2022, In: Biofilm. 4, 100080.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis
Lerche, C. J., Schwartz, F., Pries-Heje, M. M., Fosbøl, E. L., Iversen, Kasper, Jensen, Peter Østrup, Høiby, Niels, Hyldegaard, Ole, Bundgård, Henning & Moser, Claus Ernst, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 805964.Research output: Contribution to journal › Review › Research › peer-review
- Published
The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment
Lichtenberg, Mads, Jakobsen, Tim Holm, Kühl, Michael, Kolpen, Mette, Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: FEMS Microbiology Reviews. 46, 5, 13 p., fuac018.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adaptive Immune Response to Mycobacterium abscessus Complex (MABSC) in Cystic Fibrosis and the Implications of Cross-Reactivity
Mauch, R. M., Jensen, Peter Østrup, Qvist, T., Kolpen, M., Moser, Claus Ernst, Pressler, T., Nolasco da Silva, M. T., Høiby, Niels & Copenhagen Study Group on Mycobacterial Infections in Cystic Fibrosis, C. S. G. O. M. I. I. C. F., 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 858398.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel Borrelia-specific real-time PCR assay is not suitable for diagnosing Lyme neuroborreliosis
Pedersen, Regitze Renee, Kragh, K. N., Fritz, Blaine Gabriel, Ørbæk, M., Jensen, Peter Østrup, Lebech, Anne-Mette & Bjarnsholt, Thomas, 2022, In: Ticks and Tick-borne Diseases. 13, 5, 101971.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment
Thomsen, K., Kobayashi, O., Kishi, K., Shirai, R., Jensen, Peter Østrup, Heydorn, A., Hentzer, M., Calum, Henrik Pierre, Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 7, p. 458-476Research output: Contribution to journal › Review › Research › peer-review
- Published
Immune Response to Biofilm Growing Pulmonary Pseudomonas aeruginosa Infection
Thomsen, K., Høiby, Niels, Jensen, Peter Østrup, Ciofu, Oana & Moser, Claus Ernst, 2022, In: Biomedicines. 10, 9, 2064.Research output: Contribution to journal › Review › Research › peer-review
- 2021
- Published
Catalase protects biofilm of Staphylococcus aureus against daptomycin activity
El Haj, C., Lichtenberg, Mads, Nielsen, K. L., Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: Antibiotics. 10, 5, 511.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperbaric oxygen treatment impacts oxidative stress markers in patients with necrotizing soft-tissue infection
Hedetoft, M., Jensen, Peter Østrup, Moser, Claus Ernst, Vinkel, J. & Hyldegaard, Ole, 2021, In: Journal of Investigative Medicine. 69, 7, p. 1330-1338Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Soluble ICAM-1 is modulated by hyperbaric oxygen treatment and correlates with disease severity and mortality in patients with necrotizing soft-tissue infection
Hedetoft, M., Moser, Claus Ernst, Jensen, Peter Østrup, Vinkel, J. & Hyldegaard, Ole, 2021, In: Journal of Applied Physiology. 130, 3, p. 729-736 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Misleading mental models: Ceci n’est pas un biofilm
Jensen, Peter Østrup & Rumbaugh, K., 2021, In: APMIS. 129, 10, p. 577-578 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa
Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, Morten Levin, Toyofuku, M., Nomura, N., Kolpen, Mette, Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune Responses to Pseudomonas aeruginosa Biofilm Infections
Moser, Claus Ernst, Jensen, Peter Østrup, Thomsen, K., Kolpen, M., Rybtke, Morten Levin, Lauland, A. S., Trøstrup, H. & Tolker-Nielsen, Tim, 2021, In: Frontiers in Immunology. 12, 625597.Research output: Contribution to journal › Review › Research › peer-review
- Published
Delayed neutrophil recruitment allows nascent Staphylococcus aureus biofilm formation and immune evasion
Pettygrove, B. A., Kratofil, R. M., Alhede, M., Jensen, Peter Østrup, Newton, M., Qvortrup, Klaus, Pallister, K. B., Bjarnsholt, Thomas, Kubes, P., Voyich, J. M. & Stewart, P. S., Aug 2021, In: Biomaterials. 275, 13 p., 120775.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Extracellular Polysaccharide Matrix of Pseudomonas aeruginosa Biofilms Is a Determinant of Polymorphonuclear Leukocyte Responses
Rybtke, Morten Levin, Jensen, Peter Østrup, Nielsen, Claus Henrik & Tolker-Nielsen, Tim, 2021, In: Infection and Immunity. 89, 1Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct contribution of hyperbaric oxygen therapy to human neutrophil function and antibiotic efficacy against Staphylococcus aureus
Schwartz, F. A., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Laulund, A. S., Woetmann, Anders , Høiby, Niels & Moser, Claus Ernst, 2021, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 129, 9, p. 566-573Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes
Alhede, M., Lorenz, M., Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, H. C., Bay, Lene & Bjarnsholt, Thomas, 2020, In: Medical Microbiology and Immunology. 209, p. 669–680Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The origin of extracellular DNA in bacterial biofilm infections in vivo
Alhede, M., Alhede, M., Qvortrup, Klaus, Kragh, K. N., Jensen, Peter Østrup, Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Pathogens and Disease. ftaa018.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human immune cell mobilization during exercise: effect of IL-6 receptor blockade
Bay, M. L., Heywood, S., Wedell-Neergaard, A. S., Schauer, T., Lehrskov, L. L., Christensen, R. H., Legård, G. E., Jensen, Peter Østrup, Krogh-Madsen, Rikke & Ellingsgaard, H., 2020, In: Experimental Physiology. 105, 12, p. 2086-2098 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology
Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653Research output: Contribution to journal › Journal article › Research › peer-review
- Published
64Cu-DOTATATE positron emission tomography (PET) of borrelia burgdorferi infection: In vivo imaging of macrophages in experimental model of lyme arthritis
Clausen, Anne Skovsbo, Ørbæk, M., Pedersen, Regitze Renee, Jensen, Peter Østrup, Lebech, Anne-Mette & Kjær, Andreas, 2020, In: Diagnostics. 10, 10, 11 p., 790.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lactobacillus rhamnosus strains of oral and vaginal origin show strong antifungal activity in vitro
Jørgensen, Mette Rose, Rikvold, P. T., Lichtenberg, Mads, Jensen, Peter Østrup, Kragelund, C. & Twetman, Svante, 2020, In: Journal of Oral Microbiology. 12, 1, 8 p., 1832832.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Staphylococcus aureus augments release of matrix metalloproteinase-8 from human polymorphonuclear leukocytes
Kirketerp-Møller, K., Bjarnsholt, Thomas, Jensen, Peter Østrup & Ågren, Magnus, 2020, In: Acta Dermato-Venereologica. 100, 15, p. 1-2 2 p., adv00232.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation
Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neutrophil count in sputum is associated with increased sputum glucose and sputum L-lactate in cystic fibrosis
Nielsen, B. U., Kolpen, M., Jensen, Peter Østrup, Katzenstein, T., Pressler, T., Ritz, C., Mathiesen, I. H. M. & Faurholt-Jepsen, D., 2020, In: P L o S One. 15, 9, 12 p., e0238524.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction
Bjarnsholt, Thomas, Jensen, Peter Østrup & Alhede, M., 2019, In: Pathogens and Disease. 77, 5, ftz052.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms
Crabbé, A., Jensen, Peter Østrup, Bjarnsholt, Thomas & Coenye, T., 2019, In: Trends in Microbiology. 27, 10, p. 850-863Research output: Contribution to journal › Review › Research › peer-review
- Published
ADDITION OF GLUCOSE PROVIDES MYCOBACTERIUM ABSCESSUS BIOFILM WITH PROTECTION AGAINST AMIKACIN
Demant, M., Kristensen, S., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup & Kolpen, M., 2019, In: Pediatric Pulmonology. 54, S2, p. S298-S299Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The inflamed sputum in lower respiratory tract infection: l-lactate levels are correlated to neutrophil accumulation
Fredman, G., Kolpen, Mette, Hertz, F. B., Petersen, P. T., Jensen, A. V., Baunbæk-Egelund, G., Ravn, Pernille, Jensen, Peter Østrup & Faurholt-Jepsen, Daniel, 2019, In: APMIS. 127, 2, p. 72-79Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air
Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-Jepsen, Daniel, Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxygen restriction generates difficult-to-culture p. Aeruginosa
Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Crone, S., Kragh, K. N., Kolpen, Mette, Sønderholm, M., Andersson, M., Koch, A., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2019, In: Frontiers in Microbiology. 10, AUG, 15 p., 1992.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis
Lerche, C. J., Christophersen, L. J., Goetze, J. P., Nielsen, P. R., Thomsen, K., Enevold, C., Høiby, Niels, Jensen, Peter Østrup, Bundgård, Henning & Moser, Claus Ernst, 2019, In: PLoS ONE. 14, 4, 16 p., e0215333.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Markers of bone turnover are reduced in patients with CF related diabetes; the role of glucose
Mathiesen, I. H., Hitz, Mette Friberg, Katzenstein, T. L., Oturai, P., Skov, M., Jørgensen, Niklas Rye, Jensen, Peter Østrup, Mikkelsen, C. R., Krogh-Madsen, Rikke, Pressler, T. & Faurholt-Jepsen, D., 2019, In: Journal of Cystic Fibrosis. 18, 3, p. 436-441Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic therapy as personalized medicine - general considerations and complicating factors
Moser, Claus Ernst, Lerche, C. J., Thomsen, K., Hartvig, T., Schierbeck, J., Jensen, Peter Østrup, Ciofu, Oana & Høiby, Niels, 2019, In: APMIS. 127, 5, p. 361-371Research output: Contribution to journal › Review › Research › peer-review
- Published
Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients
Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms
Gade, P. A. V., Olsen, T. B., Jensen, Peter Østrup, Kolpen, Mette, Høiby, Niels, Henneberg, K. Å. & Sams, T., 2018, In: PLoS ONE. 13, 6, 16 p., e0198909.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implants induce a new niche for microbiomes
Jakobsen, Tim Holm, Eickhardt, S. R., Gheorghe, Alexandra Gabriella, Stenqvist, C., Sønderholm, M., Stavnsberg, C., Jensen, Peter Østrup, Odgaard, Anders, Whiteley, M., Moser, Claus Ernst, Hvolris, J., Hougen, H. P. & Bjarnsholt, Thomas, 1 Aug 2018, In: APMIS - Journal of Pathology, Microbiology and Immunology. 126, 8, p. 685-692 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis
Mauch, R. M., Jensen, Peter Østrup, Moser, Claus Ernst, Levy, C. E. & Høiby, Niels, 2018, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17, 2, p. 143-152Research output: Contribution to journal › Review › Research › peer-review
- Published
Extracellular hydrogen peroxide measurements using a flow injection system in combination with microdialysis probes – potential and challenges
Moßhammer, Maria, Schrameyer, V., Jensen, Peter Østrup, Koren, K. & Kühl, Michael, 2018, In: Free Radical Biology & Medicine. 128, p. 111-123Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model
Sønderholm, M., Koren, K., Wangpraseurt, D., Jensen, Peter Østrup, Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas & Kühl, Michael, 2018, In: npj Biofilms and Microbiomes. 4, 11 p., 3.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor
Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Feb 2018, In: International Wound Journal. 15, 1, p. 123-132Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase
Damgaard, D., Bjørn, M. E., Jensen, Peter Østrup & Nielsen, Claus Henrik, Dec 2017, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 1203-1208 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of Oxygen Therapies in Wound Healing: Focus on Topical and Hyperbaric Oxygen Treatment
Gottrup, F., Dissemond, J., Baines, C., Frykberg, R., Jensen, Peter Østrup, Kot, J., Kröger, K. & Longobardi, P., 1 May 2017, In: Journal of Wound Care. 26, Sup5, p. S1-S43Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnosis of biofilm infections in cystic fibrosis patients
Høiby, Niels, Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup, Kolpen, Mette, Qvist, T., Aanæs, Kasper, Pressler, T., Skov, M. & Ciofu, Oana, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 339-343 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Microenvironmental characteristics and physiology of biofilms in chronic infections of CF patients are strongly affected by the host immune response
Jensen, Peter Østrup, Kolpen, Mette, Kragh, K. N. & Kühl, Michael, 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 276–288 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Probiotic Lactobacillus reuteri has antifungal effects on oral Candida species in vitro
Jørgensen, Mette Rose, Kragelund, C., Jensen, Peter Østrup, Keller, M. K. & Twetman, Svante, 2017, In: Journal of Oral Microbiology. 9, 1, 8 p., 1274582.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
O-2 AFFECTS THE ACTIVITY OF AMIKACIN ON MYCOBACTERIUM ABSCESSUS BIOFILM
Kolpen, M., Ravnholt, C., Qvist, T., Kragh, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, Sep 2017, In: Pediatric Pulmonology. 52, S47, p. S359-S360 379.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin
Kolpen, Mette, Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperbaric oxygen treatment augments tobramycin efficacy in experimental staphylococcus aureus endocarditis
Lerche, C. J., Christophersen, L. J., Kolpen, Mette, Nielsen, P. R., Trøstrup, H., Thomsen, K., Hyldegaard, Ole, Bundgård, Henning, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Antimicrobial Agents. 50, 3, p. 406-412Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilms and host response - helpful or harmful
Moser, Claus Ernst, Pedersen, H. T., Lerche, C. J., Kolpen, Mette, Line, L., Thomsen, K., Høiby, Niels & Jensen, Peter Østrup, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 320-338 19 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Heading for centennial anniversary and beyond
Norrild, B., Ralfkiaer, E., Bjarnsholt, Thomas & Jensen, Peter Østrup, Dec 2017, In: APMIS. 125, 12, p. 1133-1133Research output: Contribution to journal › Editorial › Research
- Published
Pseudomonas aeruginosa aggregate formation in an alginate bead model system exhibits In Vivo-like characteristics
Sønderholm, M., Kragh, K. N., Koren, K., Jakobsen, Tim Holm, Darch, S., Alhede, M., Jensen, Peter Østrup, Whiteley, M., Kühl, Michael & Bjarnsholt, Thomas, May 2017, In: Applied and Environmental Microbiology. 83, 9, 15 p., e00113-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The consequences of being in an infectious biofilm – microenvironmental conditions governing antibiotic tolerance
Sønderholm, M., Bjarnsholt, Thomas, Alhede, M., Kolpen, Mette, Jensen, Peter Østrup, Kühl, Michael & Kragh, K. N., 2017, In: International Journal of Molecular Sciences. 18, 12, 14 p., 2688.Research output: Contribution to journal › Review › Research › peer-review
- Published
Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines—implications for delayed wound closure?
Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Oct 2017, In: Pathogens and Disease. 75, 7, 10 p., ftx068.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds
Trøstrup, H., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Molecular Sciences. 18, 7, 13 p., 1359.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Diffusion retardation by binding of tobramycin in an alginate biofilm model
Cao, B., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Sneppen, Kim, Høiby, Niels, Moser, Claus Ernst & Sams, T., 21 Apr 2016, In: P L o S One. 11, 4, 11 p., e0153616.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of pulmonary and lymph node dendritic cells during chronic Pseudomonas aeruginosa lung infection in mice
Damlund, D. S. M., Christophersen, L., Jensen, Peter Østrup, Alhede, M., Høiby, Niels & Moser, Claus Ernst, Jun 2016, In: APMIS - Journal of Pathology, Microbiology and Immunology. 124, 6, p. 500-507 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions
Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment
Kolpen, Mette, Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Development of a rechargeable optical hydrogen peroxide sensor - sensor design and biological application
Koren, K., Jensen, Peter Østrup & Kühl, Michael, 2016, In: Analyst. 141, 14, p. 4332-4339 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of multicellular aggregates in biofilm formation
Kragh, K. N., Hutchison, J. B., Melaugh, G., Rodesney, C., Roberts, A. E. L., Irie, Y., Jensen, Peter Østrup, Diggle, S. P., Allen, R. J., Gordon, V. & Bjarnsholt, Thomas, 22 Mar 2016, In: mBio. 7, 2, 11 p., e00237-16.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incidence of Propionibacterium acnes in initially culture-negative thioglycollate broths: a prospective cohort study at a Danish University Hospital
Kvich, Lasse Andersson, Jensen, Peter Østrup, Justesen, U. S. & Bjarnsholt, Thomas, Nov 2016, In: Clinical Microbiology and Infection. 22, 11, p. 941-945Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model
Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils
Thomsen, K., Christophersen, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, Claus Ernst & Høiby, Niels, Jul 2016, In: Human Vaccines & Immunotherapeutics. 12, 7, p. 1690-1699 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Antibiofilm Properties of Acetic Acid
Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model
Cao, B., Christophersen, L., Thomsen, K., Sønderholm, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2015, In: The Journal of antimicrobial chemotherapy. 70, 7, p. 2057-2063 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients
Ciofu, Oana, Tolker-Nielsen, Tim, Jensen, Peter Østrup, Wang, H. & Høiby, Niels, 2015, In: Advanced Drug Delivery Reviews. 85, p. 7-23 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Denitrification by cystic fibrosis pathogens - Stenotrophomonas maltophilia is dormant in sputum
Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas, Line, L., Hansen, C. R., Dalbøge, C. S., Hansen, N., Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2015, In: International Journal of Medical Microbiology. 305, 1, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis
Lerche, C. J., Christophersen, L. J., Trøstrup, H., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Bundgaard, H., Høiby, Niels & Moser, C., 1 Dec 2015, In: European Journal of Clinical Microbiology & Infectious Diseases. 34, 12, p. 2349-2357 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study
Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils
Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Jul 2015, In: Infection and Immunity. 83, 7, p. 2686-2693 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Bactericidal effect of colistin on planktonic Pseudomonas aeruginosa is independent of hydroxyl radical formation
Brochmann, R. P., Toft, A., Ciofu, Oana, Briales, A., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, 2014, In: International Journal of Antimicrobial Agents. 43, 2, p. 140-147 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasmodium falciparum avoids change in erythrocytic surface expression of phagocytosis markers during inhibition of nitric oxide synthase activity
Hempel, C., Kohnke, H., Maretty, L., Jensen, Peter Østrup, Staalsø, Trine & Kurtzhals, Jørgen, Nov 2014, In: Molecular and Biochemical Parasitology. 198, 1, p. 29-36 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms
Jensen, Peter Østrup, Briales, A., Brochmann, R. P., Wang, H., Kragh, K. N., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Ciofu, Oana, 2014, In: Pathogens and Disease. 70, 3, p. 440-443 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exhaled breath analysis using electronic nose in cystic fibrosis and primary ciliary dyskinesia patients with chronic pulmonary infections
Joensen, O., Paff, T., Haarman, E. G., Skovgaard, I. M., Jensen, Peter Østrup, Bjarnsholt, Thomas & Nielsen, Kim G., 2014, In: PLOS ONE. 9, 12, p. 1-15 15 p., e115584.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nitric oxide production by polymorphonuclear leukocytes in infected cystic fibrosis sputum consumes oxygen
Kolpen, Mette, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Rickelt, L. F., Kühl, Michael, Hempel, C., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Clinical and Experimental Immunology. 177, 1, p. 310–319 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
Kolpen, Mette, Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Liengaard, L., Kharazmi, A., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: PLOS ONE. 9, 1, p. e84353 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymorphonuclear leukocytes restrict growth of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients
Kragh, K. N., Alhede, M., Jensen, Peter Østrup, Moser, Claus Ernst, Scheike, Thomas, Jacobsen, C. S., Poulsen, Steen Seier, Eickhardt-Sørensen, S. R., Trostrup, H., Christoffersen, L., Hougen, H. P., Rickelt, L. F., Kühl, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2014, In: Infection and Immunity. 82, 11, p. 4477-4486 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
Line, L., Alhede, M., Kolpen, Mette, Kühl, Michael, Ciofu, Oana, Bjarnsholt, Thomas, Moser, Claus Ernst, Toyofuku, M., Nomura, N., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Frontiers in Microbiology. 5, 11 p., 554.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
The in vivo biofilm
Bjarnsholt, Thomas, Alhede, M., Alhede, M., Eickhardt-Sørensen, S. R., Moser, Claus Ernst, Kühl, Michael, Jensen, Peter Østrup & Høiby, Niels, 2013, In: Trends in Microbiology. 21, 9, p. 466-474 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model
Cavanagh, J. P., Granslo, H. N., Fredheim, E. A., Christophersen, L., Jensen, Peter Østrup, Thomsen, K., van Gennip, M., Klingenberg, C., Flaegstad, T., Moser, Claus Ernst & Alhede, M., Sep 2013, In: The Journal of antimicrobial chemotherapy. 68, 9, p. 2106-10 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms
Chiang, W., Nilsson, M., Jensen, Peter Østrup, Høiby, Niels, Nielsen, T., Givskov, Michael & Tolker-Nielsen, Tim, May 2013, In: Antimicrobial Agents and Chemotherapy. 57, 5, p. 2352-61 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
Jakobsen, T. H., Hansen, M. A., Jensen, P. Ø., Hansen, L., Riber, L., Cockburn, A. P. I., Kolpen, M., Hansen, C. R., Ridderberg, W., Eickhardt-Sørensen, S. R., Hansen, M., Kerpedjiev, P., Alhede, M., Qvortrup, K., Burmølle, M., Moser, C. E., Kühl, M., Ciofu, O., Givskov, M., Sørensen, S. J. & 2 others, , 2013, In: P L o S One. 8, 7, 17 p., e68484.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors
Jakobsen, Tim Holm, Bjarnsholt, Thomas, Jensen, Peter Østrup, Givskov, Michael & Høiby, Niels, Jul 2013, In: Future Microbiology. 8, 7, p. 901-21 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sublethal ciprofloxacin treatment leads to rapid development of high-level ciprofloxacin resistance during long-term experimental evolution of Pseudomonas aeruginosa
Jørgensen, K. M., Wassermann, T., Jensen, Peter Østrup, Hengzuang, W., Molin, S., Høiby, Niels & Ciofu, Oana, Sep 2013, In: Antimicrobial Agents and Chemotherapy. 57, 9, p. 4215-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model
Trøstrup, H., Thomsen, K., Christophersen, L. J., Hougen, H. P., Bjarnsholt, Thomas, Jensen, Peter Østrup, Kirkby, N., Calum, H., Høiby, Niels & Moser, Claus Ernst, Mar 2013, In: Wound Repair and Regeneration. 21, 2, p. 292-299 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Bead-size directed distribution of Pseudomonas aeruginosa results in distinct inflammatory response in a mouse model of chronic lung infection
Christophersen, L. J., Trøstrup, H., Damlund, D. S. M., Bjarnsholt, Thomas, Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, 2012, In: Experimental and clinical endocrinology. 170, 2, p. 222-30 10 p., 170.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetical analysis of all Danish patients diagnosed with chronic granulomatous disease
Jakobsen, M. A., Katzenstein, T. L., Valerius, N. H., Roos, D., Fisker, N., Mogensen, T. H., Jensen, Peter Østrup & Barington, T., Nov 2012, In: Scandinavian Journal of Immunology. 76, 5, p. 505-11 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 20166228
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
Research output: Contribution to journal › Journal article › Research › peer-review
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2837
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
Research output: Contribution to journal › Journal article › Research › peer-review
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
Research output: Contribution to journal › Journal article › Research › peer-review
Published