Thomas Bjarnsholt
Professor
Bacteriology
Nørre Allé 14
2200 København N
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Antimicrobials and Non-Healing Wounds. Evidence, controversies and suggestions-key messages
Gottrup, F., Apelqvist, J., Bjarnsholt, Thomas, Cooper, R., Moore, Z., Peters, E. J. G. & Probst, S., 2014, In: Journal of Wound Care. 23, 10, p. 477-8, 480, 482 4 p.Research output: Contribution to journal › Journal article › Research
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Establishing a consensus on wound infection definitions
Haesler, E., Swanson, T., Ousey, K., Larsen, D., Carville, K., Bjarnsholt, Thomas & Haesler, P., 2022, In: Journal of Wound Care. 31, S12, p. S48-S59Research output: Contribution to journal › Journal article › Research › peer-review
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Towards diagnostic guidelines for biofilm-associated infections
Hall-Stoodley, L., Stoodley, P., Kathju, S., Høiby, Niels, Moser, Claus Ernst, William Costerton, J., Moter, A. & Bjarnsholt, Thomas, Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 127-145 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduced Skin Microbiome Diversity in Infancy Is Associated with Increased Risk of Atopic Dermatitis in High-Risk Children
Halling, A. S., Fritz, Blaine Gabriel, Gerner, T., Rinnov, M. R., Bay, Lene, Knudgaard, M. H., Ravn, N. H., Trautner, S., Ruge, I. F., Olesen, C., Díiaz-Pinées Cort, I., Skov, Lone, Sørensen, N., Møller Rønnstad, A. T., Thomsen, Simon Francis, Egeberg, Alexander, Jakasa, I., Kezic, S., Bjarnsholt, Thomas & Thyssen, Jacob Pontoppidan, 2023, In: Journal of Investigative Dermatology. 143, 10, p. 2030-2038 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inflammation in Achromobacter xylosoxidans infected cystic fibrosis patients
Hansen, C. R., Pressler, T., Nielsen, K. G., Jensen, Peter Østrup, Bjarnsholt, Thomas & Høiby, Niels, 1 Jan 2010, In: Journal of Cystic Fibrosis. 9, 1, p. 51-58 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of patients with odontogenic necrotizing soft tissue infections in the head and neck area: A retrospective analysis
Hansen, S. U., Jespersen, Frederik Viktor Bang, Markvart, Merete, Hyldegaard, Ole, Plaschke, Christina Caroline, Bjarnsholt, Thomas, Nielsen, Claus Henrik & Jensen, Simon Storgård, 2023, In: Acta Odontologica Scandinavica. 82, 1, p. 40-47Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Antibiotic implant irrigation and deep infection: A retrospective study of 1508 patients undergoing breast reconstruction with implants
Hemmingsen, Mathilde Nejrup, Bennedsen, A. K., Kullab, R. B., Weltz, T. K., Ørholt, M., Norlin, C. B., Kalstrup, J., Bredgaard, R., Sørensen, Søren Johannes, Bjarnsholt, Thomas, Hølmich, Lisbet Rosenkrantz, Damsgaard, T. E., Vester-Glowinski, Peter Viktor & Herly, Mikkel, 2024, (E-pub ahead of print) In: Plastic and Reconstructive Surgery. 26 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: protocol for a randomised, double-blind, placebo-controlled trial (The BREAST-AB trial)
Hemmingsen, M. N., Larsen, A., Weltz, T. K., Ørholt, M., Wiberg, S., Bennedsen, A. K., Bille, C., Carstensen, L. F., Jensen, L. T., Bredgaard, R., Koudahl, V., Schmidt, Volker-Jürgen, Vester-Glowinski, Peter Viktor, Hølmich, Lisbet Rosenkrantz, Sørensen, Søren Johannes, Bjarnsholt, Thomas, Damsgaard, Tine M Engberg & Herly, Mikkel, 2022, In: BMJ Open. 12, 9, p. e058697Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacokinetics of Locally Applied Antibiotic Prophylaxis for Implant-Based Breast Reconstruction
Hemmingsen, Mathilde Nejrup, Bennedsen, A. K., Kullab, R. B., Norlin, C. B., Ørholt, M., Larsen, A., Bue, M., Lichtenberg, Mads, Hertz, Frederik Boëtius, Damsgaard, T. E., Vester-Glowinski, Peter Viktor, Sørensen, Søren Johannes, Bjarnsholt, Thomas & Herly, Mikkel, 2023, In: JAMA network open. 6, 12, 11 p., E2348414.Research output: Contribution to journal › Journal article › Research › peer-review
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Does an Antimicrobial Incision Drape Prevent Intraoperative Contamination? A Randomized Controlled Trial of 1187 Patients
Hesselvig, A. B., Arpi, M., Madsen, F., Bjarnsholt, Thomas, Odgaard, Anders & ICON Study Group, I. S. G., 2020, In: Clinical Orthopaedics and Related Research. 478, 5, p. 1007-1015Research output: Contribution to journal › Journal article › Research › peer-review
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Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media
Homøe, Preben, Bjarnsholt, Thomas, Wessman, M., Sørensen, H. C. F. & Johansen, Helle Krogh, 1 Oct 2009, In: European Archives of Oto-Rhino-Laryngology. 266, 10, p. 1533-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorom sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model.
Hultqvist, Louise Dahl, van Gennip, M., Jakobsen, Tim Holm, Alhede, M., Hougen, H. P., Høiby, Niels, Bjarnsholt, Thomas & Givskov, Michael, 2012, In: Journal of Antimicrobial Chemotherapy. 67, 5, p. 1198-1206 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The interaction pattern of murine serum ficolin-A with microorganisms
Hummelshøj, T., Ma, Y. J., Munthe-Fog, L., Bjarnsholt, Thomas, Moser, Claus Ernst, Skjødt, Mikkel-Ole, Romani, L., Fujita, T., Endo, Y. & Garred, P., 2012, In: P L o S One. 7, 5, p. 1-12 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Success rate of split-thickness skin grafting of chronic venous leg ulcers depends on the presence of Pseudomonas aeruginosa: a retrospective study
Høgsberg, T., Bjarnsholt, Thomas, Thomsen, J. S. & Kirketerp-Møller, K., 2011, In: P L o S One. 6, 5, p. e20492Research output: Contribution to journal › Journal article › Research › peer-review
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Success rate of split-thickness skin grafting of chronic venous leg ulcers depends on the presence of Pseudomonas aeruginosa: a retrospective study
Høgsberg, T., Bjarnsholt, Thomas, Thomsen, J. S. & Kirketerp-Møller, K., 1 Jan 2011, In: P L o S One. 6, 5, p. e20492Research output: Contribution to journal › Journal article › Research › peer-review
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ESCMID guideline for the diagnosis and treatment of biofilm infections 2014
Høiby, Niels, Bjarnsholt, Thomas, Moser, C., Bassi, G. L., Coenye, T., Donelli, G., Hall-Stoodley, L., Holá, V., Imbert, C., Kirketerp-Møller, K., Lebeaux, D., Oliver, A., Ullmann, A. J., Williams, C. & ESCMID Study Group for Biofilms (ESGB) and Consulting External Expert Werner Zimmerli, E. S. G. F. B. (. A. C. E. E. W. Z., 14 Jan 2015, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 21, Suppl. 1, p. s1-s25 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibiotic resistance of bacterial biofilms
Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael, Molin, S. & Ciofu, Oana, 2010, In: International Journal of Antimicrobial Agents. 35, 4, p. 322-332 11 p.Research output: Contribution to journal › Review › Research › peer-review
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The clinical impact of bacterial biofilms
Høiby, Niels, Ciofu, Oana, Johansen, Helle Krogh, Song, Z., Moser, Claus Ernst, Jensen, Peter Østrup, Molin, S., Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: International Journal of Oral Science. 3, 2, p. 55-65Research output: Contribution to journal › Journal article › Research › peer-review
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Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.
Høiby, Niels, Johansen, Helle Krogh, Ciofu, Oana, Jensen, Peter Østrup, Bjarnsholt, Thomas & Givskov, Michael, 2007, In: Ugeskrift for læger. 169, 48, p. 4163-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth
Høiby, Niels, Henneberg, K. Å., Wang, H., Stavnsbjerg, Camilla, Bjarnsholt, Thomas, Ciofu, Oana, Johansen, U. R. & Sams, T., 2019, In: International Journal of Antimicrobial Agents. 53, 5, p. 564-573Research output: Contribution to journal › Journal article › Research › peer-review
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Centennial celebrations of the Danish Pasteur Society
Høiby, Niels & Bjarnsholt, Thomas, 2024, In: APMIS. 132, 1, p. 3Research output: Contribution to journal › Editorial › Research
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Diagnosis of biofilm infections in cystic fibrosis patients
Høiby, Niels, Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup, Kolpen, Mette, Qvist, T., Aanæs, Kasper, Pressler, T., Skov, M. & Ciofu, Oana, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 339-343 5 p.Research output: Contribution to journal › Review › Research › peer-review
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Pseudomonas aeruginosa biofilms in cystic fibrosis
Høiby, Niels, Ciofu, Oana & Bjarnsholt, Thomas, 1 Nov 2010, In: Future Microbiology. 5, p. 1663-74 12 p.Research output: Contribution to journal › Review › Research › peer-review
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The Pseudomonas aeruginosa PSL polysaccharide is a social but noncheatable trait in biofilms
Irie, Y., Roberts, A. E. L., Kragh, K. N., Gordon, V. D., Hutchison, J., Allen, R. J., Melaugh, G., Bjarnsholt, Thomas, West, S. A. & Diggle, S. P., 2017, In: mBio. 8, 3, 13 p., e00374-17.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Novel sampling technique maintaining the two-dimensional organization of microbes during cultivation from chronic wounds: The Imprint method
Iversen, A. K. S., Fritz, Blaine Gabriel, Hansen, M. J., Kirketerp-Møller, K., Jakobsen, Tim Holm, Bjarnsholt, Thomas & Lichtenberg, Mads, 2024, (E-pub ahead of print) In: APMIS.Research output: Contribution to journal › Journal article › Research › peer-review
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Mucoid Pseudomonas aeruginosa Can Produce Calcium-Gelled Biofilms Independent of the Matrix Components Psl and CdrA
Jacobs, H. M., O'Neal, L., Lopatto, E., Wozniak, D. J., Bjarnsholt, Thomas & Parsek, M. R., 2022, In: Journal of Bacteriology. 204, 5Research output: Contribution to journal › Journal article › Research › peer-review
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Implants induce a new niche for microbiomes
Jakobsen, Tim Holm, Eickhardt, S. R., Gheorghe, Alexandra Gabriella, Stenqvist, C., Sønderholm, M., Stavnsberg, C., Jensen, Peter Østrup, Odgaard, Anders, Whiteley, M., Moser, Claus Ernst, Hvolris, J., Hougen, H. P. & Bjarnsholt, Thomas, 1 Aug 2018, In: APMIS - Journal of Pathology, Microbiology and Immunology. 126, 8, p. 685-692 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sampling challenges in diagnosis of chronic bacterial infections
Jakobsen, Tim Holm, Xu, Y., Bay, Lene, Schønheyder, H. C., Jakobsen, T., Bjarnsholt, Thomas & Thomsen, T. R., 2021, In: Journal of Medical Microbiology. 70, 3Research output: Contribution to journal › Review › Research › peer-review
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
Jakobsen, T. H., Hansen, M. A., Jensen, P. Ø., Hansen, L., Riber, L., Cockburn, A. P. I., Kolpen, M., Hansen, C. R., Ridderberg, W., Eickhardt-Sørensen, S. R., Hansen, M., Kerpedjiev, P., Alhede, M., Qvortrup, K., Burmølle, M., Moser, C. E., Kühl, M., Ciofu, O., Givskov, M., Sørensen, S. J. & 2 others, , 2013, In: P L o S One. 8, 7, 17 p., e68484.Research output: Contribution to journal › Journal article › Research › peer-review
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Qualitative and quantitative determination of quorum sensing inhibition in vitro
Jakobsen, Tim Holm, van Gennip, M., Hultqvist, Louise Dahl, Bjarnsholt, Thomas & Givskov, Michael, 1 Jan 2011, In: Methods in Molecular Biology. 692, 3, p. 253-263 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors
Jakobsen, Tim Holm, Bjarnsholt, Thomas, Jensen, Peter Østrup, Givskov, Michael & Høiby, Niels, Jul 2013, In: Future Microbiology. 8, 7, p. 901-21 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa
Jakobsen, Tim Holm, Bragason, S. K., Phipps, R. K., Hultqvist, Louise Dahl, van Gennip, M., Alhede, M., Skindersoe, M., Larsen, T. O., Høiby, Niels, Bjarnsholt, Thomas & Givskov, Michael, 2012, In: Applied and Environmental Microbiology. 78, 7, p. 2410-2421 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing
Jakobsen, Tim Holm, van Gennip, M., Phipps, R. K., Shanmugham, M. S., Hultqvist, Louise Dahl, Alhede, M., Skindersoe, M. E., Rasmussen, T. B., Friedrich, K., Uthe, F., Jensen, Peter Østrup, Moser, Claus Ernst, Nielsen, Kristian Fog, Eberl, L., Larsen, T. O., Tanner, D. A., Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., May 2012, In: Antimicrobial Agents and Chemotherapy. 56, 5, p. 2314-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fluorescence in situ hybridization for the tissue detection of bacterial pathogens associated with porcine infections.
Jensen, Henrik Elvang, Jensen, Louise Kruse, Barington, Kristiane, Pors, S. E., Bjarnsholt, Thomas & Boye, M., 2015, In: Methods in Molecular Biology. 1247, p. 219-134 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Symposium i Danmarks Mikrobiologiske Selskab
Jensen, L. B., Bjarnsholt, Thomas & Jacobsen, C. S., 2012, In: Ugeskrift for Laeger. 174, 12, p. 790 1 p.Research output: Contribution to journal › Journal article › Research
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Combined Staining Techniques for Demonstration of Staphylococcus aureus Biofilm in Routine Histopathology
Jensen, Louise Kruse, Henriksen, Nicole Lind, Bjarnsholt, Thomas, Kragh, K. N. & Jensen, Henrik Elvang, 2018, In: Journal of Bone and Joint Infection. 3, 1, p. 27-36Research output: Contribution to journal › Journal article › Research › peer-review
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Novel porcine model of implant-associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response
Jensen, Louise Kruse, Koch, J., Dich-Jørgensen, K., Aalbæk, Bent, Petersen, A., Fuursted, K., Bjarnsholt, Thomas, Kragh, K. N., Tøtterup, M., Bue, M., Hanberg, P., Søballe, K., Heegaard, P. M. H. & Jensen, Henrik Elvang, 2017, In: Journal of Orthopaedic Research. 35, 10, p. 2211–2221Research output: Contribution to journal › Journal article › Research › peer-review
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Specific antibodies to Staphylococcus aureus biofilm are present in serum from pigs with osteomyelitis
Jensen, Louise Kruse, Jensen, Henrik Elvang, Koch, J., Bjarnsholt, Thomas, Eickhardt-Dalbøge, S. R. & Shirtliff, M., 2015, In: In Vivo. 29, p. 555-560 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early implant-associated osteomyelitis results in a peri-implanted bacterial reservoir
Jensen, Louise Kruse, Koch, J., Aalbæk, Bent, Moodley, Arshnee, Bjarnsholt, Thomas, Kragh, K. N., Petersen, A. & Jensen, Henrik Elvang, Jan 2017, In: APMIS - Journal of Pathology, Microbiology and Immunology. 125, 1, p. 38-45 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo gentamicin susceptibility test for prevention of bacterial biofilms in bone tissue and on implants
Jensen, Louise Kruse, Bjarnsholt, Thomas, Kragh, K. N., Aalbæk, Bent, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie, Pankoke, K., Petersen, A. & Jensen, Henrik Elvang, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 2, 10 p., e01889-18.Research output: Contribution to journal › Journal article › Research › peer-review
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Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air
Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-Jepsen, Daniel, Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.Research output: Contribution to journal › Journal article › Research › peer-review
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Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in Guinea Pigs
Jensen, Peter Østrup, Lykkesfeldt, Jens, Bjarnsholt, Thomas, Hougen, H. P., Høiby, Niels & Ciofu, Oana, 2012, In: Basic & Clinical Pharmacology & Toxicology. 110, 4, p. 353-358 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Bacterial aerobic respiration is a major consumer of oxygen in sputum from patients with acute lower respiratory tract infection
Jensen, Peter Østrup, Olsen, P., Dungu, A. M., Egelund, G. B., Jensen, A. V., Ravn, P., Lindegaard, Birgitte, Hertz, Frederik Boëtius, Bjarnsholt, Thomas, Faurholt-Jepsen, D. & Kolpen, Mette, 2024, (E-pub ahead of print) In: APMIS.Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa
Jensen, Peter Østrup, Bjarnsholt, Thomas, Phipps, R., Rasmussen, T. B., Calum, H., Christoffersen, L., Moser, C., Williams, P., Pressler, T., Givskov, Michael & Høiby, Niels, 2007, In: Microbiology. 153, Pt 5, p. 1329-38 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms
Jensen, Peter Østrup, Briales, A., Brochmann, R. P., Wang, H., Kragh, K. N., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Ciofu, Oana, 2014, In: Pathogens and Disease. 70, 3, p. 440-443 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The immune system vs. Pseudomonas aeruginosa biofilms
Jensen, Peter Østrup, Givskov, Michael, Bjarnsholt, Thomas & Moser, C., 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 292-305 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?
Jensen, Ramon Gordon, Johansen, Helle Krogh, Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R. & Homøe, Preben, Jul 2017, In: European Archives of Oto-Rhino-Laryngology. 274, 7, p. 2741-2747 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cerebral abscesses with odontogenic origin: a population-based cohort study
Jespersen, Frederik Viktor Bang, Hansen, S. U., Jensen, Simon Storgård, Omland, L. H., Helweg-Larsen, J., Bjarnsholt, Thomas, Nielsen, Claus Henrik, Ziebell, M., Bodilsen, J. & Markvart, Merete, 2023, In: Clinical Oral Investigations. 27, 7, p. 3639-364Research output: Contribution to journal › Journal article › Research › peer-review
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Exhaled breath analysis using electronic nose in cystic fibrosis and primary ciliary dyskinesia patients with chronic pulmonary infections
Joensen, O., Paff, T., Haarman, E. G., Skovgaard, I. M., Jensen, Peter Østrup, Bjarnsholt, Thomas & Nielsen, Kim G., 2014, In: PLOS ONE. 9, 12, p. 1-15 15 p., e115584.Research output: Contribution to journal › Journal article › Research › peer-review
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Understanding the microbiome of diabetic foot osteomyelitis: insights from molecular and microscopic approaches
Johani, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Lipsky, B. A., Jensen, S. O., Yang, M., Dean, A., Hu, H., Vickery, K. & Malone, M., 2019, In: Clinical Microbiology and Infection. 25, 3, p. 332-339Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9755066
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
Research output: Contribution to journal › Journal article › Research › peer-review
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
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