Michael Givskov
Professor
Bacteriology
Blegdamsvej 3B, 2200 København N, 22 Bygning 22, Building: 22-2-22
Member of:
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Pseudomonas aeruginosa Microcolonies in Coronary Thrombi from Patients with ST-Segment Elevation Myocardial Infarction
Hansen, G. M., Midjord-Belstrøm, Daniel, Nilsson, Carl Martin Peter, Helqvist, S., Nielsen, Claus Henrik, Holmstrup, Palle, Tolker-Nielsen, Tim, Givskov, Michael & Hansen, Peter Riis, 2016, In: P L o S One. 11, 12, 13 p., e0168771.Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes
Alhede, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Phipps, R. K., Moser, Claus Ernst, Christophersen, L., Hultqvist, Louise Dahl, van Gennip, M., Parsek, M., Høiby, Niels, Rasmussen, T. B. & Givskov, Michael, 2009, In: Microbiology. 155, 11, p. 3500-3508 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Auranofin inhibits virulence pathways in Pseudomonas aeruginosa
Yam, J. K. H., Tan, L. Z. W., Hong, Z., Salido, M. M. S., Woo, B. Y., Yong, A. M. H., Tan, C. A. Z., Li, S. F. Y., Yang, L., Givskov, Michael & Chng, S. S., 2023, In: Bioorganic and Medicinal Chemistry. 79, 117167.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro and in vivo generation and characterization of Pseudomonas aeruginosa biofilm-dispersed cells via c-di-GMP manipulation
Chua, S. L., Hultqvist, Louise Dahl, Yuan, M., Rybtke, Morten Levin, Nielsen, Thomas Eiland, Givskov, Michael, Tolker-Nielsen, Tim & Yang, L., Aug 2015, In: Nature Protocols (Print). 10, 8, p. 1165-80 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas aeruginosa Biofilm Infections: Community Structure, Antimicrobial Tolerance and Immune Response
Rybtke, Morten Levin, Hultqvist, Louise Dahl, Givskov, Michael & Tolker-Nielsen, Tim, 2015, In: Journal of Molecular Biology. 427, 23, p. 3628-3645Research output: Contribution to journal › Review › Research › peer-review
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Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients
Høiby, Niels, Johansen, Helle Krogh, Moser, Claus Ernst, Ciofu, Oana, Jensen, Peter Østrup, Kolpen, Mette, Mandsberg, L., Givskov, Michael, Molin, S. & Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer, p. 167-184 18 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Pseudomonas aeruginosa isolates co-incubated with Acanthamoeba castellanii exhibit phenotypes similar to chronic cystic fibrosis isolates
Leong, W., Lutz, C., Williams, J., Poh, Y. H., Ken Yee, B. Y., Chua, C., Rice, S. A., Givskov, Michael, Sanderson-Smith, M. & McDougald, D., 2020, bioRxiv, 49 p.Research output: Working paper › Preprint › Research
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Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent
Bjarnsholt, Thomas, Jensen, Peter Østrup, Burmølle, Mette, Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, Claus Ernst, Molin, S., Høiby, Niels & Givskov, Michael, Feb 2005, In: Microbiology. 151, Pt 2, p. 373-83 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Pseudomonas aeruginosa uses type III secretion system to kill biofilm-associated amoebae
Matz, C., Moreno, A. M., Alhede, M., Manefield, M., Hauser, A. R., Givskov, Michael & Kjelleberg, S., 2008, In: ISME Journal. 2, 8, p. 843-852 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination
Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.Research output: Contribution to journal › Journal article › Research › peer-review
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A Linker for the Solid-Phase Synthesis of Hydroxamic Acids and Identification of HDAC6 Inhibitors
Bang, C. G., Jensen, J. F., O'Hanlon Cohrt, E., Olsen, L. B., Siyum, S. G., Mortensen, K. T., Skovgaard, T., Berthelsen, J., Yang, L., Givskov, Michael, Qvortrup, K. & Nielsen, Thomas Eiland, Oct 2017, In: ACS Combinatorial Science. 19, 10, p. 657-669 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A broad range quorum sensing inhibitor working through sRNA inhibition
Jakobsen, Tim Holm, Warming, A. N., Vejborg, R. M., Moscoso, J. A., Stegger, M., Lorenzen, F., Rybtke, Morten Levin, Andersen, Jens Bo, Petersen, R., Andersen, P. S., Nielsen, Thomas Eiland, Tolker-Nielsen, Tim, Filloux, A., Ingmer, Hanne & Givskov, Michael, 2017, In: Scientific Reports. 7, 1, 12 p., 9857.Research output: Contribution to journal › Journal article › Research › peer-review
A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms
Allesen-Holm, M., Barken, K. B., Yang, L., Klausen, M., Webb, J. S., Kjelleberg, S., Molin, S., Givskov, Michael & Tolker-Nielsen, T., 2006, In: Molecular Microbiology. 59, 4, p. 1114-28 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A convenient procedure for the solid-phase synthesis of hydroxamic acids on PEGA resins
Nandurkar, N. S., Petersen, R., Qvortrup, K., Komnatnyy, V. V., Taveras, K. M., Le Quement, S. T., Frauenlob, R., Givskov, Michael & Nielsen, Thomas Eiland, 28 Dec 2011, In: Tetrahedron Letters. 52, 52, p. 7121-7124 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A genetic switch controls Pseudomonas aeruginosa surface colonization
Manner, C., Dias Teixeira, R., Saha, D., Kaczmarczyk, A., Zemp, R., Wyss, F., Jaeger, T., Laventie, B. J., Boyer, S., Malone, J. G., Qvortrup, K., Andersen, Jens Bo, Givskov, Michael, Tolker-Nielsen, Tim, Hiller, S., Drescher, K. & Jenal, U., 2023, In: Nature Microbiology. 8, p. 1520–1533Research output: Contribution to journal › Journal article › Research › peer-review
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A mariner transposon vector adapted for mutagenesis in oral streptococci
Nilsson, M., Christiansen, N., Høiby, Niels, Twetman, Svante, Givskov, Michael & Tolker-Nielsen, Tim, Jun 2014, In: MicrobiologyOpen. 3, 3, p. 333-40 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A mouse ear skin model to study the dynamics of innate immune responses against Staphylococcus aureus biofilms
Abdul Hamid, A. I., Nakusi, L., Givskov, Michael, Chang, Y. T., Marquès, C. & Gueirard, P., 2020, In: BMC Microbiology. 20, 1, 12 p., 22.Research output: Contribution to journal › Journal article › Research › peer-review
A novel and sensitive method for the quantification of N-3-oxoacyl homoserine lactones using gas chromatography-mass spectrometry: application to a model bacterial biofilm
Charlton, T. S., de Nys, R., Netting, A., Kumar, N., Hentzer, M., Givskov, Michael & Kjelleberg, S., 2000, In: Environmental Microbiology. 2, 5, p. 530-41 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A possible correlation between periodontitis and ischaemic heart disease
Hansen, G. M., Holmstrup, Palle, Tolker-Nielsen, Tim, Køllgaard, T., Nielsen, C. H., Givskov, Michael & Hansen, Peter Riis, 2014, In: Ugeskrift for Laeger.Research output: Contribution to journal › Journal article › Research › peer-review
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Absence of Bacteria on Coronary Angioplasty Balloons from Unselected Patients: Results with Use of a High Sensitivity Polymerase Chain Reaction Assay
Hansen, G. M., Nilsson, M., Nielsen, Claus Henrik, Holmstrup, Palle, Helqvist, S., Tolker-Nielsen, Tim, Givskov, Michael & Hansen, Peter Riis, 2015, In: PloS one. 10, 12, p. 1-11 11 p., e0145657.Research output: Contribution to journal › Journal article › Research › peer-review
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Acetic acid and a buffer
Bjarnsholt, Thomas, Givskov, Michael, P, H., Høiby, Niels, PO, J., HK, J. & K, K., 2010, Patent No. WO2009155931, 30 Jan 2010Research output: Patent
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Acquisition of resistance to carbapenem and macrolide-mediated quorum sensing inhibition by Pseudomonas aeruginosa via ICETn4371 6385
Ding, Y., Teo, J. W. P., Drautz-Moses, D. I., Schuster, S. C., Givskov, Michael & Yang, L., 2018, In: Communications Biology. 1, 10 p., 57.Research output: Contribution to journal › Journal article › Research › peer-review
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Adaptation to an Amoeba Host Leads to Pseudomonas aeruginosa Isolates with Attenuated Virulence
Leong, W., Poh, W. H., Williams, J., Lutz, C., Mozammel Hoque, M., Poh, Y. H., Yee, B. Y. K., Chua, C., Givskov, Michael, Sanderson-Smith, M., Rice, S. A. & McDougald, D., 2022, In: Applied and Environmental Microbiology. 88, 5, e02322.Research output: Contribution to journal › Journal article › Research › peer-review
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Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing
Jakobsen, Tim Holm, van Gennip, M., Phipps, R. K., Shanmugham, M. S., Hultqvist, Louise Dahl, Alhede, M., Skindersoe, M. E., Rasmussen, T. B., Friedrich, K., Uthe, F., Jensen, Peter Østrup, Moser, Claus Ernst, Nielsen, Kristian Fog, Eberl, L., Larsen, T. O., Tanner, D. A., Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., May 2012, In: Antimicrobial Agents and Chemotherapy. 56, 5, p. 2314-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Alginate overproduction affects Pseudomonas aeruginosa biofilm structure and function
Hentzer, M., Teitzel, G. M., Balzer, G. J., Heydorn, A., Molin, S., Givskov, Michael & Parsek, M. R., 2001, In: Journal of Bacteriology. 183, 18, p. 5395-401 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
An attractive surface: gram-negative bacterial biofilms
Schembri, M., Givskov, Michael & Klemm, P., 2002, In: Science Signaling. 2002, 132, p. re6Research output: Contribution to journal › Journal article › Research › peer-review
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An in vitro model of bacterial infections in wounds and other soft tissues
Werthén, M., Henriksson, L., Jensen, Peter Østrup, Sternberg, C., Givskov, Michael & Bjarnsholt, Thomas, 2010, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 118, 2, p. 156-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
An inhibitor of bacterial quorum sensing reduces mortalities caused by Vibriosis in rainbow trout (Oncorhynchus mykiss, Walbaum)
Rasch, M., Buch, C., Austin, B., Slierendrecht, W. J., Ekmann, K. S., Larsen, J. L., Johansen, C., Riedel, K., Eberl, L., Givskov, Michael & Gram, L., 2004, In: Systematic and Applied Microbiology. 27, 3, p. 350-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein
Schreiber, K., Boes, N., Eschbach, M., Jaensch, L., Wehland, J., Bjarnsholt, T., Givskov, Michael, Hentzer, M. & Schobert, M., 2006, In: Journal of Bacteriology. 188, 2, p. 659-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Analysis of the multimer resolution system encoded by the parCBA operon of broad-host-range plasmid RP4
Eberl, L., Kristensen, C. S., Givskov, Michael, Grohmann, E., Gerlitz, M. & Schwab, H., 1994, In: Molecular Microbiology. 12, 1, p. 131-41 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibiofilm Properties of Acetic Acid
Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibiotic and biosurfactant properties of cyclic lipopeptides produced by fluorescent Pseudomonas spp. from the sugar beet rhizosphere
Nielsen, T. H., Sørensen, D., Tobiasen, C., Andersen, Jens Bo, Christophersen, C., Givskov, Michael & Sørensen, J., 2002, In: Applied and Environmental Microbiology. 68, 7, p. 3416-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibiotic resistance of bacterial biofilms
Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael, Molin, S. & Ciofu, Oana, 2010, In: International Journal of Antimicrobial Agents. 35, 4, p. 322-332 11 p.Research output: Contribution to journal › Review › Research › peer-review
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Antibiotics inhibit tumor and disease activity in cutaneous T cell lymphoma
Lindahl, L. M., Willerslev-Olsen, A., Gjerdrum, L. M. R., Nielsen, P. R., Blümel, E., Rittig, A. H., Celis, P., Herpers, B., Becker, J. C., Stausbøl-Grøn, B., Wasik, M. A., Gluud, M., Fredholm, S., Buus, T. B., Johansen, C., Nastasi, C., Peiffer, L., Kubat, L., Bzorek, M., Eriksen, J. O. & 11 others, , 26 Sep 2019, In: Blood. 134, 13, p. 1072-1083Research output: Contribution to journal › Journal article › Research › peer-review
Application of molecular tools for in situ monitoring of bacterial growth activity
Molin, S. & Givskov, Michael, 1999, In: Environmental Microbiology. 1, 5, p. 383-91 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Applying insights from biofilm biology to drug development - can a new approach be developed?
Bjarnsholt, Thomas, Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Oct 2013, In: Nature Reviews. Drug Discovery. 12, 10, p. 791-808 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Associational Resistance to Predation by Protists in a Mixed Species Biofilm
Goh, Y. F., Røder, Henriette Lyng, Chan, S. H., Ismail, M. H., Madsen, Jonas Stenløkke, Lee, K. W. K., Sørensen, Søren Johannes, Givskov, Michael, Burmølle, Mette, Rice, S. A. & McDougald, D., 2023, In: Applied and Environmental Microbiology. 89, 2, 16 p., e0174122.Research output: Contribution to journal › Journal article › Research › peer-review
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Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors
Hentzer, M., Wu, H., Andersen, Jens Bo, Riedel, K., Rasmussen, T. B., Bagge, N., Kumar, N., Schembri, M. A., Song, Z., Kristoffersen, P., Manefield, M., Costerton, J. W., Molin, S., Eberl, L., Steinberg, P., Kjelleberg, S., Høiby, Niels & Givskov, Michael, 2003, In: EMBO Journal. 22, 15, p. 3803-15 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa
van Gennip, M., Moser, C., Hultqvist, Louise Dahl, Bjarnsholt, Thomas, Calum, H., Jensen, Peter Østrup, Christophersen, L., Hougen, H. P., Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Dec 2009, In: Journal of Antimicrobial Chemotherapy. 64, 6, p. 1241-50 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Autofluorescence in samples obtained from chronic biofilm infections – “all that glitters is not gold”
Eickhardt-Dalbøge, S. R., Kragh, K. N., Schrøder, S., Poulsen, Steen Seier, Sillesen, Henrik, Givskov, Michael, Høiby, Niels, Bjarnsholt, Thomas & Alhede, M., 2015, In: Pathogens and Disease. 73, 4, 4 p., ftv012.Research output: Contribution to journal › Letter › Research › peer-review
Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cftr(-/-) mice
Hoffmann, N., Lee, B., Hentzer, M., Rasmussen, T. B., Song, Z., Johansen, H. K., Givskov, Michael & Høiby, N., 2007, In: Antimicrobial Agents and Chemotherapy. 51, 10, p. 3677-87 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bacteria-triggered release of antimicrobial agents
Komnatnyy, V. V., Chiang, W., Tolker-Nielsen, Tim, Givskov, Michael & Nielsen, T. E., 7 Jan 2014, In: Angewandte Chemie (International ed. in English). 53, 2, p. 439-41 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes
Jakobsen, Tim Holm, Tolker-Nielsen, Tim & Givskov, Michael, Sep 2017, In: International Journal of Molecular Sciences. 18, 9, 27 p., 1970.Research output: Contribution to journal › Review › Research › peer-review
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Bacterial biofilm formation and treatment in soft tissue fillers
Alhede, M., Er, O., Eickhardt, S., Kragh, K., Alhede, M., Hultqvist, Louise Dahl, Poulsen, Steen Seier, Givskov, Michael, Christensen, L. H., Høiby, Niels, Tvede, M. & Bjarnsholt, Thomas, 30 Jan 2014, In: Pathogens and Disease. 70, p. 339-346 8 p.Research output: Contribution to journal › Journal article › Research
Bacterial biofilms: prokaryotic adventures in multicellularity
Webb, J. S., Givskov, Michael & Kjelleberg, S., 2003, In: Current Opinion in Microbiology. 6, 6, p. 578-85 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial genotoxins induce T cell senescence
Mathiasen, S. L., Gall Mas, Laura, Pateras, I. S., Theodorou, S. D. P., Namini, Martin Rich Javadi, Hansen, Morten Bagge, Martin, O. C. B., Vadivel, Chella Krishna, Ntostoglou, K., Butter, D., Givskov, Michael, Geisler, Carsten, Akbar, A. N., Gorgoulis, V. G., Frisan, T., Ødum, Niels & Krejsgaard, T., 2021, In: Cell Reports. 35, 10, 109220.Research output: Contribution to journal › Journal article › Research › peer-review
Bacterial signals and antagonists: the interaction between bacteria and higher organisms
Rice, S. A., Givskov, Michael, Steinberg, P. & Kjelleberg, S., 1999, In: Journal of Molecular Microbiology and Biotechnology. 1, 1, p. 23-31 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Beyond nutrition: health-promoting foods by quorum-sensing inhibition
Givskov, Michael, 2012, In: Future Microbiology. 7, 9, p. 1025-1028 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biofilm formation by Staphylococcus epidermidis on peritoneal dialysis catheters and the effects of extracellular products from Pseudomonas aeruginosa
Pihl, M., Arvidsson, A., Skepö, M., Nilsson, M., Givskov, Michael, Tolker-Nielsen, Tim, Svensäter, G. & Davies, J. R., Apr 2013, In: Pathogens and Disease. 67, 3, p. 192-198 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biofilms and type III secretion are not mutually exclusive in Pseudomonas aeruginosa
Mikkelsen, H., Bond, N. J., Skindersoe, M. E., Givskov, Michael, Lilley, K. S. & Welch, M., 2009, In: Microbiology. 155, Pt 3, p. 687-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections
Burmølle, Mette, Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, Preben, Tvede, M., Nyvad, B., Tolker-Nielsen, Tim, Givskov, Michael, Moser, Claus Ernst, Kirketerp-Møller, K., Johansen, Helle Krogh, Høiby, Niels, Jensen, Peter Østrup, Sørensen, Søren Johannes & Bjarnsholt, Thomas, 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.Research output: Contribution to journal › Review › Research › peer-review
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Biofilms of pathogenic nontuberculous mycobacteria targeted by new therapeutic approaches
Aung, T. T., Yam, J. K. H., Lin, S., Salleh, S. M., Givskov, Michael, Liu, S., Lwin, N. C., Yang, L. & Beuerman, R. W., 1 Jan 2016, In: Antimicrobial Agents and Chemotherapy. 60, 1, p. 24-35 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biological Trojan horse: Antigen 43 provides specific bacterial uptake and survival in human neutrophils
Fexby, S., Bjarnsholt, Thomas, Jensen, Peter Østrup, Roos, V., Høiby, Niels, Givskov, Michael & Klemm, P., 2006, In: Infection and Immunity. 75, 1, p. 30-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bursting the bubble on bacterial biofilms: a flow cell methodology
Crusz, S. A., Popat, R., Rybtke, Morten Levin, Cámara, M., Givskov, Michael, Tolker-Nielsen, Tim, Diggle, S. P. & Williams, P., 2012, In: Biofouling. 28, 8, p. 835-842 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C-di-GMP regulates Pseudomonas aeruginosa stress response to tellurite during both planktonic and biofilm modes of growth
Chua, S. L., Sivakumar, K., Rybtke, Morten Levin, Yuan, M., Andersen, Jens Bo, Nielsen, T. E., Givskov, Michael, Tolker-Nielsen, Tim, Cao, B., Kjelleberg, S. & Yang, L., 2015, In: Scientific Reports. 5, 13 p., 10052.Research output: Contribution to journal › Journal article › Research › peer-review
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C-di-GMP regulates antimicrobial peptide resistance in Pseudomonas aeruginosa
Chua, S. L., Tan, S. Y., Rybtke, Morten Levin, Chen, Y., Rice, S. A., Kjelleberg, S., Tolker-Nielsen, Tim, Yang, L. & Givskov, Michael, 2013, In: Antimicrobial Agents and Chemotherapy. 57, 5, p. 2066-2075 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CDy14: A novel biofilm probe targeting exopolysaccharide Psl
Kwon, H. Y., Kim, J. Y., Lee, J. Y., Yam, J. K. H., Hultqvist, Louise Dahl, Xu, W., Rybtke, Morten Levin, Tolker-Nielsen, Tim, Kim, J. J., Kang, N. Y., Yang, L., Park, S. J., Givskov, Michael & Chang, Y. T., 2018, In: Chemical Communications. 54, 84, p. 11865-11868 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Carbon starvation of Pseudomonas aeruginosa biofilms selects for dispersal insensitive mutants
Nair, H. A. S., Subramoni, S., Poh, W. H., Hasnuddin, N. T. B., Tay, M., Givskov, Michael, Tolker-Nielsen, Tim, Kjelleberg, S., McDougald, D. & Rice, S. A., 2021, In: BMC Microbiology. 21, 10 p., 255.Research output: Contribution to journal › Journal article › Research › peer-review
Cell death in Pseudomonas aeruginosa biofilm development
Webb, J. S., Thompson, L. S., James, S., Charlton, T., Tolker-Nielsen, T., Koch, B., Givskov, Michael & Kjelleberg, S., 2003, In: Journal of Bacteriology. 185, 15, p. 4585-92 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of TelE, a T7SS LXG Effector Exhibiting a Conserved C-Terminal Glycine Zipper Motif Required for Toxicity
Teh, W. K., Ding, Y., Gubellini, F., Filloux, A., Poyart, C., Givskov, Michael & Dramsi, S., 2023, In: Microbiology Spectrum. 11, 4, e0148123.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of a novel multidrug resistance plasmid pSGB23 isolated from Salmonella enterica subspecies enterica serovar Saintpaul
Ding, Y., Zwe, Y. H., Chin, S. F., Kohli, G. S., Drautz-Moses, D. I., Givskov, Michael, Schlundt, J., Schuster, S. C., Yuk, H. G. & Yang, L., 2018, In: Gut Pathogens. 10, 5 p., 20.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemical biology strategies for biofilm control
Yang, L. & Givskov, Michael, 1 Jan 2015, Microbial Biofilms. Wiley-Interscience, p. 363-372 10 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Chemical biology strategies for biofilm control
Yang, L. & Givskov, Michael, 2015, In: Microbiology Spectrum. 3, 4, 7 p., MB-0019-2015.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemical mediation of bacterial surface colonisation by secondary metabolites from the red alga Delisea pulchra
Maximilian, R., De Nys, R., Holmström, C., Gram, L., Givskov, Michael, Crass, K., Kjelleberg, S. A. & Steinberg, P. D., 1998, In: Aquatic Microbial Ecology. 15, 3, p. 233-246 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cholesterol crystals enhance TLR2-and TLR4-mediated pro-inflammatory cytokine responses of monocytes to the proatherogenic oral bacterium Porphyromonas gingivalis
Køllgaard, T. M. S., Enevold, Christian, Bendtzen, K., Hansen, Peter Riis, Givskov, Michael, Holmstrup, Palle & Nielsen, Claus Henrik, 24 Feb 2017, In: P L o S One. 12, 2, 14 p., 0172773.Research output: Contribution to journal › Journal article › Research › peer-review
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Clearance of Pseudomonas aeruginosa Foreign-Body Biofilm Infections through Reduction of the Cyclic Di-GMP Level in the Bacteria
Hultqvist, Louise Dahl, van Gennip, M., Rybtke, Morten Levin, Wu, H., Chiang, W., Alhede, M., Høiby, Niels, Nielsen, T., Givskov, Michael & Tolker-Nielsen, Tim, Aug 2013, In: Infection and Immunity. 81, 8, p. 2705-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Cloning and expression in Escherichia coli of the gene for extracellular phospholipase A1 from Serratia liquefaciens
Givskov, Michael, Olsen, L. & Molin, S., 1988, In: Journal of Bacteriology. 170, 12, p. 5855-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combating biofilms
Yang, L., Liu, Y., Wu, H., Song, Z., Høiby, Niels, Molin, S. & Givskov, Michael, 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 146–157Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combination Therapy Strategy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Suppressing Multiple Quorum Sensing Pathways of P. aeruginosa
Fong, J., Zhang, C., Yang, R., Boo, Z. Z., Tan, S. K., Nielsen, Thomas Eiland, Givskov, Michael, Liu, X., Bin, W., Su, H. & Yang, L., 1 Dec 2018, In: Scientific Reports. 8, 11 p., 1155.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combination of microscopic techniques reveals a comprehensive visual impression of biofilm structure and composition
Alhede, M., Qvortrup, Klaus, Liebrechts, R., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 335-342 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combining the Petasis 3-Component Reaction with Multiple Modes of Cyclization: A Build/Couple/Pair Strategy for the Synthesis of Densely Functionalized Small Molecules
Flagstad, T., Hansen, M. R., Le Quementt, S. T., Givskov, Michael & Nielsen, T. E., Jan 2015, In: A C S Combinatorial Science. 17, 1, p. 19-23 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Communication systems as targets for biological control
Kjelleberg, S. & Givskov, Michael, 2000, 1 ed. 1 p. (Environmental Microbiology).Research output: Book/Report › Book › Research
- Published
Comparative genomic analysis of malariamosquito vector-associated novel pathogen elizabethkingia anophelis
Teo, J., Tan, S., Liu, Y., Tay, M., Ding, Y., Li, Y., Kjelleberg, S., Givskov, Michael, Lin, R. T. P. & Yang, L., 2014, In: Genome Biology and Evolution. p. 1158–1165 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative genomic analysis of rapid evolution of an extreme-drug- resistant Acinetobacter baumannii clone
Tan, S., Chua, S. L., Liu, Y., Høiby, Niels, Andersen, L. P., Givskov, Michael, Song, Z. & Yang, L., 2013, In: Genome Biology and Evolution. p. 807–818Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative microarray analysis reveals that the core biofilm-associated transcriptome of Pseudomonas aeruginosa comprises relatively few genes
Patell, S., Gu, M., Davenport, P., Givskov, Michael, Waite, R. D. & Welch, M., Jun 2010, In: Environmental Microbiology Reports. 2, 3, p. 440-448 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative systems biology analysis to study the mode of action of the isothiocyanate compound Iberin on Pseudomonas aeruginosa
Tan, S. Y., Liu, Y., Chua, S. L., Vejborg, R. M., Jakobsen, Tim Holm, Chew, S. C., Li, Y., Nielsen, T. E., Tolker-Nielsen, Tim, Yang, L. & Givskov, Michael, Nov 2014, In: Antimicrobial Agents and Chemotherapy. 58, 11, p. 6648-59 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative transcriptomic analysis of the Burkholderia cepacia tyrosine kinase bceF mutant reveals a role in tolerance to stress, biofilm formation, and virulence
Ferreira, A. A., Silva, I. I., Oliveira, V. V., Becker, J. J., Givskov, Michael, Ryan, R. R., Fernandes, F. & Moreira, L. M., May 2013, In: Applied and Environmental Microbiology. 79, 9, p. 3009-3020 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complete Genome Sequence and Transcriptomic Analysis of the Novel Pathogen Elizabethkingia anophelis in Response to Oxidative Stress
Li, Y., Liu, Y., Chew, S. C., Tay, M., Salido, M. M. S., Teo, J., Lauro, F. M., Givskov, Michael & Yang, L., Jun 2015, In: Genome Biology and Evolution. 7, 6, p. 1676-1685 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
Jakobsen, T. H., Hansen, M. A., Jensen, P. Ø., Hansen, L., Riber, L., Cockburn, A. P. I., Kolpen, M., Hansen, C. R., Ridderberg, W., Eickhardt-Sørensen, S. R., Hansen, M., Kerpedjiev, P., Alhede, M., Qvortrup, K., Burmølle, M., Moser, C. E., Kühl, M., Ciofu, O., Givskov, M., Sørensen, S. J. & 2 others, , 2013, In: P L o S One. 8, 7, 17 p., e68484.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computer-aided identification of recognized drugs as Pseudomonas aeruginosa quorum-sensing inhibitors
Yang, L., Rybtke, Morten Levin, Jakobsen, Tim Holm, Hentzer, M., Bjarnsholt, Thomas, Givskov, Michael & Tolker-Nielsen, Tim, 2009, In: Antimicrobial Agents and Chemotherapy. 53, 6, p. 2432-43 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD.
Bagge, N., Ciofu, Oana, Hentzer, M., Campbell, J. I. A., Givskov, Michael & Høiby, Niels, 2002, In: Antimicrobial Agents and Chemotherapy. 46, 11, p. 3406-11 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Copy mutants of plasmid R1: effects of base pair substitutions in the copA gene on the replication control system
Givskov, Michael & Molin, S., 1984, In: Molecular and General Genetics MGG. 194, 1-2, p. 286-92 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cranberry (Vaccinium macrocarpon) oligosaccharides decrease biofilm formation by uropathogenic Escherichia coli
Sun, J., Marais, J. P. J., Khoo, C., LaPlante, K., Vejborg, R. M., Givskov, Michael, Tolker-Nielsen, Tim, Seeram, N. P. & Rowley, D. C., Aug 2015, In: Journal of Functional Foods. 17, p. 235-242 8 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Cyclic-di-GMP is required for corneal infection by Pseudomonas aeruginosa and modulates host immunity
Hoong Yam, J. K., Aung, T. T., Chua, S. L., Cheng, Y., Kohli, G. S., Zhou, J., Constancias, F., Liu, Y., Cai, Z., Santillan Salido, M. M., Drautz-Moses, D. I., Rice, S. A., Schuster, S. C., Wu, B., Kjelleberg, S., Tolker-Nielsen, Tim, Beuerman, R. W., Givskov, Michael & Yang, L., 2017, bioRxiv, 35 p.Research output: Working paper › Preprint › Research
Detection and inhibition of bacterial cell-cell communication
Rice, S. A., McDougald, D., Givskov, Michael & Kjelleberg, S., 2008, In: Methods in Molecular Biology. 431, p. 55-68 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of Bacteria by Fluorescence in Situ Hybridization in Culture-Negative Soft Tissue Filler Lesions
Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Givskov, Michael, Janssen, M. & Christensen, L. H., 2009, In: Dermatologic Surgery. 35 Suppl 2, p. 1620-1624 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of N-acyl-homoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa
Wu, H., Song, Z., Hentzer, M., Andersen, J. B., Heydorn, A., Mathee, K., Moser, C., Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146, p. 2481-2493Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa
Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Heydorn, A., Mathee, K., Moser, Claus Ernst, Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146 ( Pt 10), p. 2481-93 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of Pathogenic Biofilms with Bacterial Amyloid Targeting Fluorescent Probe, CDy11
Kim, J. Y., Sahu, S., Yau, Y. H., Wang, X., Shochat, S. G., Nielsen, P. H., Dueholm, M. S., Otzen, D. E., Lee, J., Delos Santos, M. M. S., Yam, J. K. H., Kang, N. Y., Park, S. J., Kwon, H., Seviour, T., Yang, L., Givskov, Michael & Chang, Y. T., 13 Jan 2016, In: Journal of the American Chemical Society. 138, 1, p. 402-407 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Differentiation of Serratia liquefaciens into swarm cells is controlled by the expression of the flhD master operon
Eberl, L., Christiansen, G., Molin, S. & Givskov, Michael, 1996, In: Journal of Bacteriology. 178, 2, p. 554-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of a quorum sensing modulator pharmacophore by 3D small-molecule microarray screening
Marsden, D. M., Nicholson, R. L., Skindersoe, M. E., Galloway, W. R. J. D., Sore, H. F., Givskov, Michael, Salmond, G. P. C., Ladlow, M., Welch, M. & Spring, D. R., 7 Dec 2010, In: Organic & Biomolecular Chemistry. 8, 23, p. 5313-23 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Discovery of novel antimycobacterial drug therapy in biofilm of pathogenic nontuberculous mycobacterial keratitis
Aung, T. T., Chor, W. H. J., Yam, J. K. H., Givskov, Michael, Yang, L. & Beuerman, R. W., 2017, In: Ocular Surface. 15, 4, p. 770-783 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dispersed cells represent a distinct stage in the transition from bacterial biofilm to planktonic lifestyles
Chua, S. L., Liu, Y., Yam, J. K. H., Chen, Y., Vejborg, R. M., Tan, B. G. C., Kjelleberg, S., Tolker-Nielsen, Tim, Givskov, Michael & Yang, L., 2014, In: Nature Communications. 5, p. 1-12 13 p., 4462.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through loss of the Rieske cytochrome bc1 sub-unit
Soh, E., Smith, F., Gimenez, M. R., Yang, L., Vejborg, R. M., Fletcher, M., Halliday, N., Bleves, S., Heeb, S., Camara, M., Givskov, Michael, Hardie, K. R., Tolker-Nielsen, Tim, Ize, B. & Williams, P., 2021, bioRxiv, 43 p.Research output: Working paper › Preprint › Research
- Published
Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through lack of the Rieske cytochrome bc1sub-unit
Soh, E. Y. C., Smith, F., Gimenez, M. R., Yang, L., Vejborg, R. M., Fletcher, M., Halliday, N., Bleves, S., Heeb, S., Cámara, M., Givskov, Michael, Hardie, K. R., Tolker-Nielsen, Tim, Ize, B. & Williams, P., 2021, In: PLOS Pathogens. 17, 8, 25 p., e1009425.Research output: Contribution to journal › Journal article › Research › peer-review
Distribution of bacterial growth activity in flow-chamber biofilms
Sternberg, C., Christensen, B. B., Johansen, T., Toftgaard Nielsen, A., Andersen, J. B., Givskov, Michael & Molin, S., 1999, In: Applied and Environmental Microbiology. 65, 9, p. 4108-17 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution, organization, and ecology of bacteria in chronic wounds
Kirketerp-Møller, K., Jensen, Peter Østrup, Fazli, M., Madsen, K. G., Pedersen, J., Moser, C., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Aug 2008, In: Journal of Clinical Microbiology. 46, 8, p. 2717-22 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disulfide Bond-Containing Ajoene Analogues As Novel Quorum Sensing Inhibitors of Pseudomonas aeruginosa
Fong, J., Yuan, M., Jakobsen, Tim Holm, Mortensen, K. T., Delos Santos, M. M. S., Chua, S. L., Yang, L., Tan, C. H., Nielsen, Thomas Eiland & Givskov, Michael, 12 Jan 2017, In: Journal of Medicinal Chemistry. 60, 1, p. 215-227Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Draft Genome Sequence of the Model Naphthalene-Utilizing Organism Pseudomonas putida OUS82
Tay, M., Roizman, D., Cohen, Y., Tolker-Nielsen, Tim, Givskov, Michael & Yang, L., 2014, In: Genome Announcements. 2, 1, p. 1 1 p., e01161-13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamics and spatial distribution of beta-lactamase expression in Pseudomonas aeruginosa biofilms.
Bagge, N., Hentzer, M., Andersen, Jens Bo, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1168-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5838523
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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C-di-GMP regulates Pseudomonas aeruginosa stress response to tellurite during both planktonic and biofilm modes of growth
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Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes
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