Michael Givskov
Professor
Bacteriology
Blegdamsvej 3B, 2200 København N, 22 Bygning 22, Building: 22-2-22
Member of:
- 2008
- Published
The Pseudomonas aeruginosa autoinducer dodecanoyl-homoserine lactone inhibits the putrescine synthesis in human cells
Kristiansen, S., Bjarnsholt, Thomas, Adeltoft, D., Ifversen, P. & Givskov, Michael, 2008, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 116, 5, p. 361-371 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thermal injury induces impaired function in polymorphonuclear neutrophil granulocytes and reduced control of burn wound infection
Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Christoffersen, L., Damlund, D. S. M., Alhede, M., Bjarnsholt, Thomas, Hougen, H. P., Givskov, Michael, Jacobsen, G. K. & Høiby, Niels, 2008, In: Clinical and Experimental Immunology. 156, 1, p. 102-110 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Why chronic wounds will not heal: a novel hypothesis
Bjarnsholt, Thomas, Kirketerp-Møller, K., Jensen, Peter Østrup, Madsen, K. G., Phipps, R. K., Krogfelt, K., Høiby, Niels & Givskov, Michael, 2008, In: Wound Repair and Regeneration. 16, 1, p. 2-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Microbiological aspects of phyllosoma rearing of the ornate rock lobster Panulirus ornatus
Bourne, D., Høj, L., Webster, N., Payne, M., Skindersøe, M., Givskov, Michael & Hall, M., 22 Aug 2007, In: Aquaculture. 268, 1-4 SPEC. ISS., p. 274-287 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cftr(-/-) mice
Hoffmann, N., Lee, B., Hentzer, M., Rasmussen, T. B., Song, Z., Johansen, H. K., Givskov, Michael & Høiby, N., 2007, In: Antimicrobial Agents and Chemotherapy. 51, 10, p. 3677-87 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effects of iron on DNA release and biofilm development by Pseudomonas aeruginosa
Yang, L., Barken, K. B., Skindersoe, M. E., Christensen, A. B., Givskov, Michael & Tolker-Nielsen, T., 2007, In: Microbiology. 153, Pt 5, p. 1318-28 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.
Høiby, Niels, Johansen, Helle Krogh, Ciofu, Oana, Jensen, Peter Østrup, Bjarnsholt, Thomas & Givskov, Michael, 2007, In: Ugeskrift for læger. 169, 48, p. 4163-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model
Hultqvist, Louise Dahl, Moser, C., Jensen, Peter Østrup, Rasmussen, T. B., Christophersen, L., Kjelleberg, S., Kumar, N., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2007, In: Microbiology. 153, Pt 7, p. 2312-20 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Profiling acylated homoserine lactones in Yersinia ruckeri and influence of exogenous acyl homoserine lactones and known quorum-sensing inhibitors on protease production
Kastbjerg, V. G., Nielsen, K. F., Dalsgaard, I., Rasch, M., Bruhn, J. B., Givskov, Michael & Gram, L., 2007, In: Journal of Applied Microbiology. 102, 2, p. 363-74 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing antagonism from marine organisms
Skindersoe, M. E., Ettinger-Epstein, P., Rasmussen, T. B., Bjarnsholt, T., de Nys, R. & Givskov, Michael, 2007, In: Marine Biotechnology. 10, 1, p. 56-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quorum sensing antagonism from marine organisms
Skindersoe, M. E., Ettinger-Epstein, P., Rasmussen, T. B., Bjarnsholt, Thomas, de Nys, R. & Givskov, Michael, 2007, In: Marine Biotechnology. 10, 1, p. 56-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing in Serratia
Van Houdt, R., Givskov, Michael & Michiels, C. W., 2007, In: FEMS Microbiology Reviews. 31, 4, p. 407-24 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing signals are produced by Aeromonas salmonicida and quorum sensing inhibitors can reduce production of a potential virulence factor
Rasch, M., Kastbjerg, V. G., Bruhn, J. B., Dalsgaard, I., Givskov, Michael & Gram, L., 2007, In: Diseases of Aquatic Organisms. 78, 2, p. 105-13 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens
Bjarnsholt, T. & Givskov, Michael, 2007, In: Philosophical Transactions of the Royal Society of London. Biological Sciences. 362, 1483, p. 1213-22 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum-sensing regulation of adhesion in Serratia marcescens MG1 is surface dependent
Labbate, M., Zhu, H., Thung, L., Bandara, R., Larsen, M. R., Willcox, M. D. P., Givskov, Michael, Rice, S. A. & Kjelleberg, S., 2007, In: Journal of Bacteriology. 189, 7, p. 2702-11 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa
Jensen, Peter Østrup, Bjarnsholt, Thomas, Phipps, R., Rasmussen, T. B., Calum, H., Christoffersen, L., Moser, C., Williams, P., Pressler, T., Givskov, Michael & Høiby, Niels, 2007, In: Microbiology. 153, Pt 5, p. 1329-38 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Silver against Pseudomonas aeruginosa biofilms
Bjarnsholt, Thomas, Kirketerp-Møller, K., Kristiansen, S., Phipps, R., Nielsen, A. K., Jensen, Peter Østrup, Høiby, Niels & Givskov, Michael, 2007, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 115, 8, p. 921-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Well-known quorum sensing inhibitors do not affect bacterial quorum sensing-regulated bean sprout spoilage
Rasch, M., Rasmussen, T. B., Andersen, J. B., Persson, T., Nielsen, J., Givskov, Michael & Gram, L., 2007, In: Journal of Applied Microbiology. 102, 3, p. 826-37 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms
Allesen-Holm, M., Barken, K. B., Yang, L., Klausen, M., Webb, J. S., Kjelleberg, S., Molin, S., Givskov, Michael & Tolker-Nielsen, T., 2006, In: Molecular Microbiology. 59, 4, p. 1114-28 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein
Schreiber, K., Boes, N., Eschbach, M., Jaensch, L., Wehland, J., Bjarnsholt, T., Givskov, Michael, Hentzer, M. & Schobert, M., 2006, In: Journal of Bacteriology. 188, 2, p. 659-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biological Trojan horse: Antigen 43 provides specific bacterial uptake and survival in human neutrophils
Fexby, S., Bjarnsholt, Thomas, Jensen, Peter Østrup, Roos, V., Høiby, Niels, Givskov, Michael & Klemm, P., 2006, In: Infection and Immunity. 75, 1, p. 30-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Expedient total synthesis of pyrrothine natural products and analogs
Hjelmgaard, T., Givskov, Michael & Nielsen, J., 2006, In: Organic & Biomolecular Chemistry. 5, 2, p. 344-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Furanones
de Nys, R., Givskov, Michael, Kumar, N., Kjelleberg, S. & Steinberg, P. D., 2006, In: Progress in Molecular and Subcellular Biology. 42, p. 55-86 31 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing inhibitors: a bargain of effects
Rasmussen, T. B. & Givskov, Michael, 2006, In: Microbiology. 152, Pt 4, p. 895-904 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum-sensing inhibitors as anti-pathogenic drugs
Rasmussen, T. B. & Givskov, Michael, 2006, In: International Journal of Medical Microbiology. 296, 2-3, p. 149-61 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional
Shrout, J. D., Chopp, D. L., Just, C. L., Hentzer, M., Givskov, Michael & Parsek, M. R., 2006, In: Molecular Microbiology. 62, 5, p. 1264-77 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Erratum: Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis (Infection and Immunity (2005) 73, 4 (2504-2514))
Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, Aug 2005, In: Infection and Immunity. 73, 8, p. 5290 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent
Bjarnsholt, Thomas, Jensen, Peter Østrup, Burmølle, Mette, Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, Claus Ernst, Molin, S., Høiby, Niels & Givskov, Michael, Feb 2005, In: Microbiology. 151, Pt 2, p. 373-83 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Enhancer-binding proteins with a forkhead-associated domain and the sigma54 regulon in Myxococcus xanthus fruiting body development
Jelsbak, L., Givskov, Michael & Kaiser, D., 2005, In: Proceedings of the National Academy of Science of the United States of America. 102, 8, p. 3010-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudo-monas aeruginosa infections.
Bjarnsholt, Thomas, Jensen, P. Ø., Rasmussen, T. B., Christoffersen, L., Calum, Henrik Pierre, Hentzer, M., Hougen, H. P., Rygaard, J., Moser, Claus Ernst, Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: F E M S Microbiology. 151, p. 3873-3880 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections
Bjarnsholt, T., Jensen, P. Ø., Rasmussen, T. B., Christophersen, L., Calum, H., Hentzer, M., Hougen, H., Rygaard, J., Moser, C., Eberl, L., Høiby, N. & Givskov, Michael, 2005, In: Microbiology. 151, Pt 12, p. 3873-80 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identity and effects of quorum-sensing inhibitors produced by Penicillium species
Rasmussen, T. B., Skindersoe, M. E., Bjarnsholt, T., Phipps, R. K., Christensen, K. B., Jensen, Peter Østrup, Andersen, Jens Bo, Koch, B., Larsen, T. O., Hentzer, M., Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: Microbiology. 151, Pt 5, p. 1325-40 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of bacterial quorum-sensing signals in spoilage of bean sprouts
Rasch, M., Andersen, Jens Bo, Nielsen, K. F., Flodgaard, L. R., Christensen, Henrik, Givskov, Michael & Gram, L., 2005, In: Applied and Environmental Microbiology. 71, 6, p. 3321-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Nonbioluminescent strains of Photobacterium phosphoreum produce the cell-to-cell communication signal N-(3-Hydroxyoctanoyl)homoserine lactone
Flodgaard, L. R., Dalgaard, P., Andersen, Jens Bo, Nielsen, K. F., Givskov, Michael & Gram, L., 2005, In: Applied and Environmental Microbiology. 71, 4, p. 2113-20 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model
Bragonzi, A., Worlitzsch, D., Pier, G. B., Timpert, P., Ulrich, M., Hentzer, M., Andersen, Jens Bo, Givskov, Michael, Conese, M. & Doring, G., 2005, In: Journal of Infectious Diseases. 192, 3, p. 410-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis
Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, 2005, In: Infection and Immunity. 73, 4, p. 2504-14 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing inhibition: targeting chemical communication in gram-negative bacteria
Persson, T., Givskov, Michael & Nielsen, J., 2005, In: Current Medicinal Chemistry. 12, 26, p. 3103-15 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector
Rasmussen, T. B., Bjarnsholt, T., Skindersoe, M. E., Hentzer, M., Kristoffersen, P., Köte, M., Nielsen, J., Eberl, L. & Givskov, Michael, 2005, In: Journal of Bacteriology. 187, 5, p. 1799-814 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
The LuxR receptor: the sites of interaction with quorum-sensing signals and inhibitors
Koch, B., Liljefors, T., Persson, T., Nielsen, J., Kjelleberg, S. & Givskov, Michael, 2005, In: Microbiology. 151, Pt 11, p. 3589-602 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome analysis of Pseudomonas aeruginosa biofilm development: Anaerobic respiration and iron limitation
Hentzer, M., Eberl, L. & Givskov, Michael, 2005, In: Biofilms. 2, 1, p. 37-61 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Quorum sensing in Gram-negative bacteria
Wu, H., Song, Z., Høiby, Niels & Givskov, Michael, May 2004, In: Progress in Natural Science. 14, 5, p. 377-387 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
An inhibitor of bacterial quorum sensing reduces mortalities caused by Vibriosis in rainbow trout (Oncorhynchus mykiss, Walbaum)
Rasch, M., Buch, C., Austin, B., Slierendrecht, W. J., Ekmann, K. S., Larsen, J. L., Johansen, C., Riedel, K., Eberl, L., Givskov, Michael & Gram, L., 2004, In: Systematic and Applied Microbiology. 27, 3, p. 350-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamics and spatial distribution of beta-lactamase expression in Pseudomonas aeruginosa biofilms.
Bagge, N., Hentzer, M., Andersen, Jens Bo, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1168-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effects of quorum-sensing on immunoglobulin G responses in a rat model of chronic lung infection with Pseudomonas aeruginosa
Wu, H., Song, Z., Givskov, Michael & Høiby, N., 2004, In: Microbes and Infection. 6, 1, p. 34-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Phosphorus limitation enhances biofilm formation of the plant pathogen Agrobacterium tumefaciens through the PhoR-PhoB regulatory system
Danhorn, T., Hentzer, M., Givskov, Michael, Parsek, M. R. & Fuqua, C., 2004, In: Journal of Bacteriology. 186, 14, p. 4492-501 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Presence of acylated homoserine lactones (AHLs) and AHL-producing bacteria in meat and potential role of AHL in spoilage of meat
Bruhn, J. B., Christensen, A. B., Flodgaard, L. R., Nielsen, K. F., Larsen, T. O., Givskov, Michael & Gram, L., 2004, In: Applied and Environmental Microbiology. 70, 7, p. 4293-302 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production.
Bagge, N., Schuster, M., Hentzer, M., Ciofu, Oana, Givskov, Michael, Greenberg, E. P. & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1175-87 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Pseudomonas aeruginosa with lasI quorum-sensing deficiency during corneal infection
Zhu, H., Bandara, R., Conibear, T. C. R., Thuruthyil, S. J., Rice, S. A., Kjelleberg, S., Givskov, Michael & Willcox, M. D. P., 2004, In: Investigative Ophthalmology & Visual Science. 45, 6, p. 1897-903 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1
Labbate, M., Queck, S. Y., Koh, K. S., Rice, S. A., Givskov, Michael & Kjelleberg, S., 2004, In: Journal of Bacteriology. 186, 3, p. 692-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Rational design and synthesis of new quorum-sensing inhibitors derived from acylated homoserine lactones and natural products from garlic
Persson, T., Hansen, T. H., Rasmussen, T. B., Skindersø, M. E., Givskov, Michael & Nielsen, J., 2004, In: Organic & Biomolecular Chemistry. 3, 2, p. 253-62 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice
Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Molin, S., Givskov, Michael & Høiby, Niels, 2004, In: Journal of Antimicrobial Chemotherapy. 53, 6, p. 1054-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors
Hentzer, M., Wu, H., Andersen, Jens Bo, Riedel, K., Rasmussen, T. B., Bagge, N., Kumar, N., Schembri, M. A., Song, Z., Kristoffersen, P., Manefield, M., Costerton, J. W., Molin, S., Eberl, L., Steinberg, P., Kjelleberg, S., Høiby, Niels & Givskov, Michael, 2003, In: EMBO Journal. 22, 15, p. 3803-15 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Bacterial biofilms: prokaryotic adventures in multicellularity
Webb, J. S., Givskov, Michael & Kjelleberg, S., 2003, In: Current Opinion in Microbiology. 6, 6, p. 578-85 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Cell death in Pseudomonas aeruginosa biofilm development
Webb, J. S., Thompson, L. S., James, S., Charlton, T., Tolker-Nielsen, T., Koch, B., Givskov, Michael & Kjelleberg, S., 2003, In: Journal of Bacteriology. 185, 15, p. 4585-92 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification and characterization of a GDSL esterase gene located proximal to the swr quorum-sensing system of Serratia liquefaciens MG1
Riedel, K., Talker-Huiber, D., Givskov, Michael, Schwab, H. & Eberl, L., 2003, In: Applied and Environmental Microbiology. 69, 7, p. 3901-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics
Arevalo-Ferro, C., Hentzer, M., Reil, G., Görg, A., Kjelleberg, S., Givskov, Michael, Riedel, K. & Eberl, L., 2003, In: Environmental Microbiology. 5, 12, p. 1350-69 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
Influence of food preservation parameters and associated microbiota on production rate, profile and stability of acylated homoserine lactones from food-derived Enterobacteriaceae
Ravn Flodgaard, L., Christensen, A. B., Molin, S., Givskov, Michael & Gram, L., 2003, In: International Journal of Food Microbiology. 84, 2, p. 145-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections
Hentzer, M. & Givskov, Michael, 2003, In: Journal of Clinical Investigation. 112, 9, p. 1300-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing : a novel target for the treatment of biofilm infections
Hentzer, M., Eberl, L., Nielsen, J. & Givskov, Michael, 2003, In: BioDrugs. 17, 4, p. 241-50 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum-sensing-directed protein expression in Serratia proteamaculans B5a
Christensen, A. B., Riedel, K., Eberl, L., Flodgaard, L. R., Molin, S., Gram, L. & Givskov, Michael, 2003, In: Microbiology. 149, Pt 2, p. 471-83 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Surface motility in Pseudomonas sp. DSS73 is required for efficient biological containment of the root-pathogenic microfungi Rhizoctonia solani and Pythium ultimum
Andersen, Jens Bo, Koch, B., Nielsen, T. H., Sørensen, D., Hansen, M., Nybroe, O., Christophersen, C., Sørensen, J., Molin, S. & Givskov, Michael, 2003, In: Microbiology. 149, Pt 1, p. 37-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis of furanone-based natural product analogues with quorum sensing antagonist activity
Hjelmgaard, T., Persson, T., Rasmussen, T. B., Givskov, Michael & Nielsen, J., 2003, In: Bioorganic & Medicinal Chemistry. 11, 15, p. 3261-71 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers
Olsen, J. A., Severinsen, R., Rasmussen, T. B., Hentzer, M., Givskov, Michael, Nielsen, J. & Nielsen, J., 11 Feb 2002, In: Bioorganic and Medicinal Chemistry Letters. 12, 3, p. 325-328 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
An attractive surface: gram-negative bacterial biofilms
Schembri, M., Givskov, Michael & Klemm, P., 2002, In: Science Signaling. 2002, 132, p. re6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic and biosurfactant properties of cyclic lipopeptides produced by fluorescent Pseudomonas spp. from the sugar beet rhizosphere
Nielsen, T. H., Sørensen, D., Tobiasen, C., Andersen, Jens Bo, Christophersen, C., Givskov, Michael & Sørensen, J., 2002, In: Applied and Environmental Microbiology. 68, 7, p. 3416-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD.
Bagge, N., Ciofu, Oana, Hentzer, M., Campbell, J. I. A., Givskov, Michael & Høiby, Niels, 2002, In: Antimicrobial Agents and Chemotherapy. 46, 11, p. 3406-11 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Food spoilage--interactions between food spoilage bacteria
Gram, L., Ravn, L., Rasch, M., Bruhn, J. B., Christensen, A. B. & Givskov, Michael, 2002, In: International Journal of Food Microbiology. 78, 1-2, p. 79-97 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
Genetic analysis of functions involved in the late stages of biofilm development in Burkholderia cepacia H111
Huber, B., Riedel, K., Köthe, M., Givskov, Michael, Molin, S. & Eberl, L., 2002, In: Molecular Microbiology. 46, 2, p. 411-26 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover
Manefield, M., Rasmussen, T. B., Henzter, M., Andersen, Jens Bo, Steinberg, P., Kjelleberg, S. & Givskov, Michael, 2002, In: Microbiology. 148, Pt 4, p. 1119-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification and characterization of an N-acylhomoserine lactone-dependent quorum-sensing system in Pseudomonas putida strain IsoF
Steidle, A., Allesen-Holm, M., Riedel, K., Berg, G., Givskov, Michael, Molin, S. & Eberl, L., 2002, In: Applied and Environmental Microbiology. 68, 12, p. 6371-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound
Hentzer, M., Riedel, K., Rasmussen, T. B., Heydorn, A., Andersen, Jens Bo, Parsek, M. R., Rice, S. A., Eberl, L., Molin, S., Høiby, Niels, Kjelleberg, S. & Givskov, Michael, 2002, In: Microbiology. 148, Pt 1, p. 87-102 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Lipopeptide production in Pseudomonas sp. strain DSS73 is regulated by components of sugar beet seed exudate via the Gac two-component regulatory system
Koch, B., Nielsen, T. H., Sørensen, D., Andersen, J. B., Christophersen, C., Molin, S., Givskov, Michael, Sørensen, J. & Nybroe, O., 2002, In: Applied and Environmental Microbiology. 68, 9, p. 4509-16 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Lysophosphatidic acid inhibition of the accumulation of Pseudomonas aeruginosa PAO1 alginate, pyoverdin, elastase and LasA
Laux, D. C., Corson, J. M., Givskov, Michael, Hentzer, M., Møller, A., Wosencroft, K. A., Olson, J. C., Krogfelt, K. A., Goldberg, J. B. & Cohen, P., 2002, In: Microbiology. 148, Pt 6, p. 1709-23 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative effects of medium hardness and nutrient availability on the swarming motility of Serratia liquefaciens
Bees, M. A., Andresén, P., Mosekilde, E. & Givskov, Michael, 2002, In: Bulletin of Mathematical Biology. 64, 3, p. 565-87 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers
Olsen, J. A., Severinsen, R. E., Rasmussen, T. B., Hentzer, M., Givskov, Michael & Nielsen, J., 2002, In: Bioorganic & Medicinal Chemistry Letters. 12, 3, p. 325-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting quorum sensing for treatment of chronic bacterial biofilm infections
Hentzer, M., Givskov, Michael & Parsek, M. R., 2002, In: Laboratory Medicine. 33, 4, p. 295-306 12 p.Research output: Contribution to journal › Review › Research › peer-review
The identification of a tetracycline resistance gene tet(M), on a Tn916-like transposon, in the Bacillus cereus group
Agersø, Y., Jensen, L. B., Givskov, Michael & Roberts, M. C., 2002, In: FEMS Microbiology Letters. 214, 2, p. 251-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
Alginate overproduction affects Pseudomonas aeruginosa biofilm structure and function
Hentzer, M., Teitzel, G. M., Balzer, G. J., Heydorn, A., Molin, S., Givskov, Michael & Parsek, M. R., 2001, In: Journal of Bacteriology. 183, 18, p. 5395-401 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Genetic and chemical tools for investigating signaling processes in biofilms
Charlton, T., Givskov, Michael, deNys, R., Andersen, Jens Bo, Hentzer, M., Rice, S. & Kjelleberg, S., 2001, In: Methods in Enzymology. 336, p. 108-28 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
Halogenated furanones from the red alga, Delisea pulchra, inhibit carbapenem antibiotic synthesis and exoenzyme virulence factor production in the phytopathogen Erwinia carotovora
Manefield, M., Welch, M., Givskov, Michael, Salmond, G. P. & Kjelleberg, S., 2001, In: F E M S Microbiology Letters. 205, 1, p. 131-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Methods for detecting acylated homoserine lactones produced by Gram-negative bacteria and their application in studies of AHL-production kinetics
Ravn, L., Christensen, A. B., Molin, S., Givskov, Michael & Gram, L., 2001, In: Journal of Microbiological Methods. 44, 3, p. 239-51 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
N-acyl homoserinelactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms
Riedel, K., Mentzer, M., Geisenberger, O., Huber, B., Steidle, A., Wu, H., Høiby, Niels, Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, p. 3249-3262Research output: Contribution to journal › Journal article › Research › peer-review
N-acyl-L-homoserine lactone-mediated regulation of the lip secretion system in Serratia liquefaciens MG1
Riedel, K., Ohnesorg, T., Krogfelt, K. A., Hansen, T. S., Omori, K., Givskov, Michael & Eberl, L., 2001, In: Journal of Bacteriology. 183, 5, p. 1805-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms
Riedel, K., Hentzer, M., Geisenberger, O., Huber, B., Steidle, A., Wu, H., Høiby, Niels, Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, Pt 12, p. 3249-62 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa mutations in lasI and rhlI quorum sensing systems result in milder chronic lung infection
Wu, H., Song, Z., Givskov, Michael, Doring, G., Worlitzsch, D., Mathee, K., Rygaard, J. & Høiby, Niels, 2001, In: Microbiology. 147, Pt 5, p. 1105-1113 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility
Huber, B., Riedel, K., Hentzer, M., Heydorn, A., Gotschlich, A., Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, Pt 9, p. 2517-28 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Visualization of N-acylhomoserine lactone-mediated cell-cell communication between bacteria colonizing the tomato rhizosphere
Steidle, A., Sigl, K., Schuhegger, R., Ihring, A., Schmid, M., Gantner, S., Stoffels, M., Riedel, K., Givskov, Michael, Hartmann, A., Langebartels, C. & Eberl, L., 2001, In: Applied and Environmental Microbiology. 67, 12, p. 5761-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
gfp-based N-acyl homoserine-lactone sensor systems for detection of bacterial communication
Andersen, J. B., Heydorn, A., Hentzer, M., Eberl, L., Geisenberger, O., Christensen, B. B., Molin, S. & Givskov, Michael, 2001, In: Applied and Environmental Microbiology. 67, 2, p. 575-85 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
A novel and sensitive method for the quantification of N-3-oxoacyl homoserine lactones using gas chromatography-mass spectrometry: application to a model bacterial biofilm
Charlton, T. S., de Nys, R., Netting, A., Kumar, N., Hentzer, M., Givskov, Michael & Kjelleberg, S., 2000, In: Environmental Microbiology. 2, 5, p. 530-41 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Communication systems as targets for biological control
Kjelleberg, S. & Givskov, Michael, 2000, 1 ed. 1 p. (Environmental Microbiology).Research output: Book/Report › Book › Research
- Published
Detection of N-acyl-homoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa
Wu, H., Song, Z., Hentzer, M., Andersen, J. B., Heydorn, A., Mathee, K., Moser, C., Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146, p. 2481-2493Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa
Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Heydorn, A., Mathee, K., Moser, Claus Ernst, Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146 ( Pt 10), p. 2481-93 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Experimental reproducibility in flow-chamber biofilms
Heydorn, A., Ersbøll, B. K., Hentzer, M., Parsek, M. R., Givskov, Michael & Molin, S., 2000, In: Microbiology. 146 ( Pt 10), p. 2409-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How Delisea pulchra furanones affect quorum sensing and swarming motility in Serratia liquefaciens MG1
Rasmussen, T. B., Manefield, M., Andersen, Jens Bo, Eberl, L., Anthoni, U., Christophersen, C., Steinberg, P., Kjelleberg, S. & Givskov, Michael, 2000, In: Microbiology. 146 Pt 12, p. 3237-44 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of gltB abolishes expression of the assimilatory nitrate reductase gene (nasB) in Pseudomonas putida KT2442
Eberl, L., Ammendola, A., Rothballer, M. H., Givskov, Michael, Sternberg, C., Kilstrup, M., Schleifer, K. H. & Molin, S., 2000, In: Journal of Bacteriology. 182, 12, p. 3368-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis
Geisenberger, O., Givskov, Michael, Riedel, K., Høiby, Niels, Tümmler, B. & Eberl, L., 2000, In: F E M S Microbiology Letters. 184, 2, p. 273-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Production of N-acyl-L-homoserine lactones by Pseudomonas aeruginosa isolates from chronic lung infections associated with cystic fibrosis
Geisenberger, O., Givskov, Michael, Riedel, K., Høiby, Niels, Tümmler, B. & Eberl, L., 2000, In: FEMS Microbiology Letters. 184, p. 273-278Research output: Contribution to journal › Journal article › Research › peer-review
Quantification of biofilm structures by the novel computer program COMSTAT
Heydorn, A., Nielsen, A. T., Hentzer, M., Sternberg, C., Givskov, Michael, Ersbøll, B. K. & Molin, S., 2000, In: Microbiology. 146 ( Pt 10), p. 2395-407 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
The interaction of thin-film flow, bacterial swarming and cell differentiation in colonies of Serratia liquefaciens
Bees, M. A., Andresén, P., Mosekilde, E. & Givskov, Michael, 2000, In: Journal of Mathematical Biology. 40, 1, p. 27-63 37 p.Research output: Contribution to journal › Journal article › Research › peer-review
rpoS gene function is a disadvantage for Escherichia coli BJ4 during competitive colonization of the mouse large intestine
Krogfelt, K. A., Hjulgaard, M., Sørensen, K., Cohen, P. & Givskov, Michael, 2000, In: Infection and Immunity. 68, 5, p. 2518-24 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5838523
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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C-di-GMP regulates Pseudomonas aeruginosa stress response to tellurite during both planktonic and biofilm modes of growth
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Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes
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