Oana Ciofu

Oana Ciofu

Professor

Member of:

    ORCID: 0000-0001-5648-4858

    Publication year:
    All
    1 - 100 out of 118Page size: 100
    1. 1994
    2. Published

      Antibodies against chromosomal beta-lactamase.

      Giwercman, B., Rasmussen, J. W., Ciofu, Oana, Clemmentsen, I., Schumacher, H. & Høiby, Niels, 1994, In: Antimicrobial Agents and Chemotherapy. 38, 10, p. 2306-10 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Development of antibiotic resistance in Pseudomonas aeruginosa during two decades of antipseudomonal treatment at the Danish CF Center.

      Ciofu, Oana, Giwercman, B., Pedersen, S. S. & Høiby, Niels, 1994, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 102, 9, p. 674-80 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. 1995
    5. Published

      Antibodies against Pseudomonas aeruginosa chromosomal beta-lactamase inpatients with cystic fibrosis are markers of the development of resistance of P. aeruginosa to beta-lactams.

      Ciofu, Oana, Giwercman, B., Walter-Rasmussen, J., Pressler, T., Pedersen, S. S. & Høiby, Niels, 1995, In: Journal of Antimicrobial Chemotherapy. 35, 2, p. 295-304 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. 1996
    7. Published

      Meropenem in cystic fibrosis patients infected with resistant Pseudomonas aeruginosa or Burkholderia cepacia and with hypersensitivity to beta-lactam antibiotics.

      Ciofu, Oana, Jensen, T., Pressler, T., Johansen, Helle Krogh, Bender Koch, Christian & Høiby, Niels, 1996, In: Clinical Microbiology and Infection. 2, 2, p. 91-98 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Quantitative analysis of the IgG and IgG subclass immune responses to chromosomal Pseudomonas aeruginosa beta-lactamase in serum from patients with cystic fibrosis by western blotting and laser scanning densitometry.

      Petersen, T. D., Ciofu, Oana, Pressler, T., Giwercman, B., Pedersen, S. S. & Høiby, Niels, 1996, In: Thorax. 51, 7, p. 733-8 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Use of carbapenems and other antibiotics for pulmonary infections in patients with cystic fibrosis.

      Høiby, Niels, Ciofu, Oana, Jensen, T., Pressler, T., Johansen, Helle Krogh & Koch, C., 1996, In: Pediatric Infectious Disease Journal. 15, 8, p. 738-43 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. 1997
    11. Published

      Pseudomonas aeruginosa isolates from patients with cystic fibrosis have different beta-lactamase expression phenotypes but are homogeneous in the ampC-ampR genetic region.

      Campbell, J. I., Ciofu, Oana & Høiby, Niels, 1997, In: Antimicrobial Agents and Chemotherapy. 41, 6, p. 1380-4 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      The clonal antibody response to Pseudomonas aeruginosa heat shock protein is highly diverse in cystic fibrosis patients.

      Ulanova, M., Petersen, T. D., Ciofu, Oana, Jensen, P., Hahn-Zoric, M., Hanson, L. A. & Høiby, Niels, 1997, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 105, 6, p. 449-56 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      The influence of allotypes on the IgG subclass response to chromosomal beta-lactamase of Pseudomonas aeruginosa in cystic fibrosis patients.

      Ciofu, Oana, Pressler, T., Pandey, J. P. & Høiby, Niels, 1997, In: Clinical and Experimental Immunology. 108, 1, p. 88-94 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. 1999
    15. Published

      Avidity of anti-P aeruginosa antibodies during chronic infection in patients with cystic fibrosis.

      Ciofu, Oana, Petersen, T. D., Jensen, P. & Høiby, Niels, 1999, In: Thorax. 54, 2, p. 141-4 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.

      Mathee, K., Ciofu, Oana, Sternberg, C., Lindum, P. W., Campbell, J. I., Jensen, P., Johnsen, A. H., Givskov, Michael, Ohman, D. E., Molin, S., Høiby, Niels & Kharazmi, A., 1999, In: Microbiology. 145 ( Pt 6), p. 1349-57 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. 2000
    18. Published

      Chromosomal beta-lactamase is packaged into membrane vesicles and secreted from Pseudomonas aeruginosa.

      Ciofu, Oana, Beveridge, T. J., Kadurugamuwa, J., Walther-Rasmussen, J. & Høiby, Niels, 2000, In: Journal of Antimicrobial Chemotherapy. 45, 1, p. 9-13 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.

      Jalal, S., Ciofu, Oana, Høiby, Niels, Gotoh, N. & Wretlind, B., 2000, In: Antimicrobial Agents and Chemotherapy. 44, 3, p. 710-2 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Rapid development in vitro and in vivo of resistance to ceftazidime in biofilm-growing Pseudomonas aeruginosa due to chromosomal beta-lactamase

      Bagge, N., Ciofu, Oana, Skovgaard, Lene Theil & Høiby, Niels, Sep 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 9, p. 589-600 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. 2001
    22. Published

      Characterization of paired mucoid/non-mucoid Pseudomonas aeruginosa isolates from Danish cystic fibrosis patients: antibiotic resistance, beta-lactamase activity and RiboPrinting.

      Ciofu, Oana, Fussing, V., Bagge, N., Koch, C. & Høiby, Niels, 2001, In: Journal of Antimicrobial Chemotherapy. 48, 3, p. 391-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth.

      Høiby, Niels, Johansen, Helle Krogh, Moser, C., Song, Z., Ciofu, Oana & Kharazmi, A., 2001, In: Microbes and Infection. 3, 1, p. 23-35 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Typing of Pseudomonas aeruginosa strains in Norwegian cystic fibrosis patients.

      Fluge, G., Ojeniyi, B., Høiby, Niels, Digranes, A., Ciofu, Oana, Hunstad, E., Haanaes, O. C. & Storrøsten, O. T., 2001, In: Clinical Microbiology and Infection. 7, 5, p. 238-43 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. 2002
    26. Published

      Antibodies against beta-lactamase can improve ceftazidime treatment of lung infection with beta-lactam-resistant Pseudomonas aeruginosa in a rat model of chronic lung infection.

      Ciofu, Oana, Bagge, N. & Høiby, Niels, 2002, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 110, 12, p. 881-91 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD.

      Bagge, N., Ciofu, Oana, Hentzer, M., Campbell, J. I. A., Givskov, Michael & Høiby, Niels, 2002, In: Antimicrobial Agents and Chemotherapy. 46, 11, p. 3406-11 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. 2003
    29. Published

      Pseudomonas aeruginosa alginate is refractory to Th1 immune response and impedes host immune clearance in a mouse model of acute lung infection.

      Song, Z., Wu, H., Ciofu, Oana, Kong, K., Høiby, Niels, Rygaard, J., Kharazmi, A. & Mathee, K., 2003, In: Journal of Medical Microbiology. 52, Pt 9, p. 731-40 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Pseudomonas aeruginosa chromosomal beta-lactamase in patients with cystic fibrosis and chronic lung infection. Mechanism of antibiotic resistance and target of the humoral immune response.

      Ciofu, Oana, 2003, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 116, p. 1-47 46 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. 2004
    32. Published

      Dynamics and spatial distribution of beta-lactamase expression in Pseudomonas aeruginosa biofilms.

      Bagge, N., Hentzer, M., Andersen, Jens Bo, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1168-74 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production.

      Bagge, N., Schuster, M., Hentzer, M., Ciofu, Oana, Givskov, Michael, Greenberg, E. P. & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1175-87 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. 2005
    35. Published

      Heterogeneity of biofilms formed by nonmucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis.

      Lee, B., Haagensen, J. A. J., Ciofu, Oana, Andersen, Jens Bo, Høiby, Niels & Molin, S., 2005, In: Journal of Clinical Microbiology. 43, 10, p. 5247-55 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Immunisation in the current management of cystic fibrosis patients.

      Malfroot, A., Adam, G., Ciofu, Oana, Döring, G., Knoop, C., Lang, A. B., Van Damme, P., Dab, I., Bush, A. & European Cystic Fibrosis Society (ECFS) Vaccination Group, E. C. F. S. (. V. G., 2005, In: Journal of Cystic Fibrosis. 4, 2, p. 77-87 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis

      Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, 2005, In: Infection and Immunity. 73, 4, p. 2504-14 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Occurrence of hypermutable Pseudomonas aeruginosa in cystic fibrosis patients is associated with the oxidative stress caused by chronic lung inflammation.

      Ciofu, Oana, Riis, B., Pressler, T., Poulsen, Henrik Enghusen & Høiby, Niels, 2005, In: Antimicrobial Agents and Chemotherapy. 49, 6, p. 2276-82 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Erratum: Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis (Infection and Immunity (2005) 73, 4 (2504-2514))

      Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, Aug 2005, In: Infection and Immunity. 73, 8, p. 5290 1 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    40. 2007
    41. Published

      Cystic fibrosis: coping with resistance

      Ciofu, Oana, Høiby, Niels, Gould, I. M. & Meer, J. W. M. V. D., 2007, Antibiotic policies: fighting resistance. Springer, p. 149-174 25 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    42. Published

      Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.

      Høiby, Niels, Johansen, Helle Krogh, Ciofu, Oana, Jensen, Peter Østrup, Bjarnsholt, Thomas & Givskov, Michael, 2007, In: Ugeskrift for læger. 169, 48, p. 4163-6 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients.

      Jelsbak, L., Johansen, Helle Krogh, Frost, A., Thøgersen, R., Thomsen, Line Elnif, Ciofu, Oana, Yang, L., Haagensen, J. A. J., Høiby, Niels & Molin, S., 2007, In: Infection and Immunity. 75, 5, p. 2214-24 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. 2008
    45. Published

      A master of adaptation and survival strategies

      Høiby, Niels, Johansen, H. K., Moser, C., Ciofu, Oana & Rehm, B. H. A., 2008, Pseudomonas. Model Organism, Pathogen, Cell Factory. Weinheim: Wiley-VCH, Vol. 2. p. 25-44 19 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    46. Published

      Generel bakteriologi

      Høiby, Niels, Ciofu, Oana, Johansen, H. K., Andersen, L. P. & Skinhøj, P., 2008, Klinisk Mikrobiologi og Infektionsmedicin. 3rd ed. København: FADL's Forlag, Vol. 4. p. 21-107 86 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    47. Published

      Investigation of the algT operon sequence in mucoid and non-mucoid Pseudomonas aeruginosa isolates from 115 Scandinavian patients with cystic fibrosis and in 88 in vitro non-mucoid revertants.

      Ciofu, Oana, Lee, B., Johannesson, M., Hermansen, N. O., Meyer, P., Høiby, Niels & Scandinavian Cystic Fibrosis Study Consortium, S. C. F. S. C., 2008, In: Microbiology. 154, Pt 1, p. 103-13 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Maximum Likelihood based comparison of the specific growth rates for P. aeruginosa and four mutator strains.

      Philipsen, K. R., Christiansen, L. E., Mandsberg, L. F., Ciofu, Oana & Madsen, H., 2008, In: Journal of Microbiological Methods. 75, 3, p. 551-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients.

      Johansen, Helle Krogh, Moskowitz, S. M., Ciofu, Oana, Pressler, T. & Høiby, Niels, 2008, In: Journal of Cystic Fibrosis. 7, 5, p. 391-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. 2009
    51. Published

      Chromosomal mechanisms of aminoglycoside resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients

      Islam, S., Oh, H., Jalal, S., Karpati, F., Ciofu, Oana, Høiby, Niels & Wretlind, B., 2009, In: Clinical Microbiology and Infection. 15, 1, p. 60-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Novel experimental Pseudomonas aeruginosa infection model mimicking long-term host-pathogen interactions in cystic fibrosis.

      Moser, Claus Ernst, van Gennip, M., Bjarnsholt, Thomas, Jensen, P. Ø., Lee, B., Hougen, H. P., Calum, Henrik Pierre, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2009, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 117, p. 95-107 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Respiratory syncytial virus infection facilitates acute colonization of Pseudomonas aeruginosa in mice

      de Vrankrijker, A. M. M., Wolfs, T. F. W., Ciofu, Oana, Høiby, Niels, van der Ent, C. K., Poulsen, Steen Seier & Johansen, Helle Krogh, 2009, In: Journal of Medical Virology. 81, 12, p. 2096-103 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Sustainable plant production in a changing world - a cross Faculty research network at KU

      Strandmark, L. B., Schjoerring, Jan K., Christensen, Søren, Nybroe, O., Pedersen, J. G. T., Eilenberg, Jørgen, Munk, Lisa, Rønn, Regin, Ciofu, Oana, Bruun, Sander & Ørum, Jens Erik, 2009.

      Research output: Contribution to conference › Poster › Research

    55. Published

      Sustainable plant production in a changing world - formation of a cross-faculty network

      Strandmark, L. B., Schjoerring, Jan K., Christensen, Søren, Nybroe, O., Torp, J., Eilenberg, Jørgen, Munk, Lisa, Rønn, Regin, Ciofu, Oana, Bruun, Sander & Ørum, Jens Erik, 2009, In: IOP Conference Series: Earth and Environmental Science. 6, Session 34, 2 p., 342014.

      Research output: Contribution to journal › Conference abstract in journal › Research

    56. Published

      Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis

      Moser, C., Gennip, M. V., Bjarnsholt, Thomas, Jensen, Peter Østrup, Lee, B., Hougen, H. P., Calum, H., Ciofu, Oana, Givskov, Michael, Molin, S. & Høiby, Niels, 1 Feb 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 2, p. 95-107 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system

      Mandsberg, L. F., Ciofu, Oana, Kirkby, N., Christiansen, L. E., Poulsen, Henrik Enghusen, Høiby, Niels, Mandsberg, L. F., Ciofu, O., Kirkby, N., Christiansen, L. E., Poulsen, Henrik Enghusen & Høiby, N., 1 Jun 2009, In: Antimicrobial Agents and Chemotherapy. 53, 6, p. 2483-91 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Published

      Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa

      van Gennip, M., Moser, C., Hultqvist, Louise Dahl, Bjarnsholt, Thomas, Calum, H., Jensen, Peter Østrup, Christophersen, L., Hougen, H. P., Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Dec 2009, In: Journal of Antimicrobial Chemotherapy. 64, 6, p. 1241-50 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. 2010
    60. Published

      Antibiotic resistance of bacterial biofilms

      Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael, Molin, S. & Ciofu, Oana, 2010, In: International Journal of Antimicrobial Agents. 35, 4, p. 322-332 11 p.

      Research output: Contribution to journal › Review › Research › peer-review

    61. Published

      Antibiotic tolerance and resistance in biofilms.

      Ciofu, Oana & Tolker-Nielsen, Tim, 2010, Biofilm Infections. Bjarnsholt, T., Moser, C., Jensen, P. Ø. & Høiby, N. (eds.). New York, USA: Springer Publishing Company, p. 215-230 16 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    62. Published

      Genetic adaptation of Pseudomonas aeruginosa during chronic lung infection of patients with cystic fibrosis: strong and weak mutators with heterogeneous genetic backgrounds emerge in mucA and/or lasR mutants

      Ciofu, Oana, Mandsberg, L. F., Bjarnsholt, Thomas, Wassermann, T. & Høiby, Niels, 2010, In: Microbiology. 156, p. 1108-1119 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

      Kolpen, Mette, Hansen, C. R., Bjarnsholt, Thomas, Moser, C., Hultqvist, Louise Dahl, van Gennip, M., Ciofu, Oana, Mandsberg, L., Kharazmi, A., Döring, G., Givskov, Michael, Høiby, Niels & Jensen, Peter Østrup, 1 Jan 2010, In: Thorax. 65, 1, p. 57-62 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. Published

      Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Jakobsen, Tim Holm, Phipps, R., Nielsen, A. K., Rybtke, Morten Levin, Tolker-Nielsen, Tim, Givskov, Michael, Høiby, Niels, Ciofu, Oana & Scandinavian Cystic Fibrosis Study Consortium, S. C. F. S. C., 1 Jan 2010, In: PLoS ONE. 5, 4, p. e10115

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. Published

      Cellular responses of A549 alveolar epithelial cells to serially collected Pseudomonas aeruginosa from cystic fibrosis patients at different stages of pulmonary infection

      Hawdon, N. A., Aval, P. S., Barnes, R. J., Gravelle, S. K., Rosengren, J., Khan, S., Ciofu, Oana, Johansen, Helle Krogh, Høiby, Niels & Ulanova, M., 1 Jul 2010, In: FEMS Immunology and Medical Microbiology. 59, 2, p. 207-20 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. Published

      Pseudomonas aeruginosa biofilms in cystic fibrosis

      Høiby, Niels, Ciofu, Oana & Bjarnsholt, Thomas, 1 Nov 2010, In: Future Microbiology. 5, p. 1663-74 12 p.

      Research output: Contribution to journal › Review › Research › peer-review

    67. 2011
    68. Published

      Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients

      Høiby, Niels, Johansen, Helle Krogh, Moser, Claus Ernst, Ciofu, Oana, Jensen, Peter Østrup, Kolpen, Mette, Mandsberg, L., Givskov, Michael, Molin, S. & Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer, p. 167-184 18 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    69. Published

      Development of antibiotic resistance and up-regulation of the antimutator gene pfpI in mutator Pseudomonas aeruginosa due to inactivation of two DNA oxidative repair genes (mutY, mutM)

      Mandsberg, L. F., Maciá, M. D., Bergmann, K. R., Christiansen, L., Alhede, M., Kirkby, N., Høiby, Niels, Oliver, A. & Ciofu, Oana, 2011, In: F E M S Microbiology Letters. 324, 1, p. 28-37 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      Mucoid Pseudomonas aeruginosa isolates maintain the biofilm formation capacity and the gene expression profiles during the chronic lung infection of CF patients

      Lee, B., Schjerling, C. K., Kirkby, N., Hoffmann, N., Borup, R., Molin, S., Høiby, Niels & Ciofu, Oana, 2011, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 119, 4-5, p. 263-74 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. Published

      The clinical impact of bacterial biofilms

      Høiby, Niels, Ciofu, Oana, Johansen, Helle Krogh, Song, Z., Moser, Claus Ernst, Jensen, Peter Østrup, Molin, S., Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: International Journal of Oral Science. 3, 2, p. 55-65

      Research output: Contribution to journal › Journal article › Research › peer-review

    72. Published

      Evolutionary dynamics of bacteria in a human host environment

      Yang, L., Jelsbak, L., Marvig, R. L., Damkiær, S., Workman, C., Rau, M. H., Hansen, S. K., Folkesson, A., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels, Sommer, M. & Molin, S., 3 May 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 18, p. 7481-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    73. Published

      Pharmacokinetics/pharmacodynamics of colistin and imipenem on mucoid and nonmucoid Pseudomonas aeruginosa biofilms

      Hengzhuang, W., Wu, H., Ciofu, Oana, Song, Z., Høiby, Niels & Wang, H., Sep 2011, In: Antimicrobial Agents and Chemotherapy. 55, 9, p. 4469-74 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    74. Published

      Pharmacokinetics/Pharmacodynamics of Colistin and Imipenem on Mucoid and Nonmucoid Pseudomonas aeruginosa Biofilms

      Hengzhuang, W., Wu, H., Ciofu, Oana, Song, Z. & Høiby, Niels, 1 Sep 2011, In: Antimicrobial Agents and Chemotherapy. 55, 9, p. 4469-74 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    75. Published

      Antibiotic tolerance and resistance in biofilms

      Ciofu, Oana & Tolker-Nielsen, Tim, 1 Dec 2011, Biofilm Infections. Springer New York, p. 215-229 15 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    76. 2012
    77. Published

      Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

      Hansen, S. K., Rau, M. H., Johansen, Helle Krogh, Ciofu, Oana, Jelsbak, L., Yang, L., Folkesson, A., Jarmer, H. Ø., Aanæs, Kasper, von Buchwald, Christian, Høiby, Niels & Molin, S., 2012, In: I S M E Journal. 6, 1, p. 31-45

      Research output: Contribution to journal › Journal article › Research › peer-review

    78. Published

      Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in Guinea Pigs

      Jensen, Peter Østrup, Lykkesfeldt, Jens, Bjarnsholt, Thomas, Hougen, H. P., Høiby, Niels & Ciofu, Oana, 2012, In: Basic & Clinical Pharmacology & Toxicology. 110, 4, p. 353-358 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. Published

      In vivo pharmacokinetics/pharmacodynamics of colistin and imipenem in Pseudomonas aeruginosa biofilm infection

      Hengzhuang, W., Wu, H., Ciofu, Oana, Song, Z. & Høiby, Niels, May 2012, In: Antimicrobial Agents and Chemotherapy. 56, 5, p. 2683-2690 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    80. Published

      A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production

      Sautter, R., Ramos, D., Schneper, L., Ciofu, Oana, Wassermann, T., Koh, C., Heydorn, A., Hentzer, M., Høiby, Niels, Kharazmi, A., Molin, S., Devries, C. A., Ohman, D. E. & Mathee, K., 1 May 2012, In: Gene. 498, 2, p. 242-253 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. Published

      Initial Pseudomonas aeruginosa infection in patients with cystic fibrosis: characteristics of eradicated and persistent isolates

      Tramper-Stranders, G. A., van der Ent, C. K., Molin, S., Yang, L., Hansen, S. K., Rau, M. H., Ciofu, Oana, Johansen, Helle Krogh & Wolfs, T. F. W., Jun 2012, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 18, 6, p. 567-74 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    82. Published

      Phenotypes selected during chronic lung infection in cystic fibrosis patients: implications for the treatment of Pseudomonas aeruginosa biofilm infections

      Ciofu, Oana, Mandsberg, L. F., Wang, H. & Høiby, Niels, Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 215-225 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. Published

      Molecular epidemiology of chronic Pseudomonas aeruginosa airway infections in cystic fibrosis

      Cramer, N., Wiehlmann, L., Ciofu, Oana, Tamm, S., Høiby, Niels & Tümmler, B., Nov 2012, In: PLOS ONE. 7, 11, e50731.

      Research output: Contribution to journal › Journal article › Research › peer-review

    84. Published

      Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

      Folkesson, A., Jelsbak, L., Yang, L., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels & Molin, S., Dec 2012, In: Nature Reviews. Microbiology. 10, 12, p. 841-851 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    85. 2013
    86. Published

      Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes

      Jakobsen, T. H., Hansen, M. A., Jensen, P. Ø., Hansen, L., Riber, L., Cockburn, A. P. I., Kolpen, M., Hansen, C. R., Ridderberg, W., Eickhardt-Sørensen, S. R., Hansen, M., Kerpedjiev, P., Alhede, M., Qvortrup, K., Burmølle, M., Moser, C. E., Kühl, M., Ciofu, O., Givskov, M., Sørensen, S. J. & 2 others, Høiby, Niels & Bjarnsholt, Thomas, 2013, In: P L o S One. 8, 7, 17 p., e68484.

      Research output: Contribution to journal › Journal article › Research › peer-review

    87. Published

      Effect of long-term voluntary exercise wheel running on susceptibility to bacterial pulmonary infections in a mouse model

      van de Weert-van Leeuwen, P. B., de Vrankrijker, A. M. M., Fentz, J., Ciofu, Oana, Wojtaszewski, Jørgen F P, Arets, H. G. M., Hulzebos, H. J., van der Ent, C. K., Beekman, J. M. & Johansen, Helle Krogh, 2013, In: P L o S One. 8, 12, 7 p., e82869.

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. Published

      High β-lactamase levels change the pharmacodynamics of β-lactam antibiotics in Pseudomonas aeruginosa biofilms

      Hengzhuang, W., Ciofu, Oana, Yang, L., Wu, H., Song, Z., Oliver, A. & Høiby, Niels, Jan 2013, In: Antimicrobial Agents and Chemotherapy. 57, 1, p. 196-204 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. Published

      P. aeruginosa in the paranasal sinuses and transplanted lungs have similar adaptive mutations as isolates from chronically infected CF lungs

      Ciofu, Oana, Johansen, Helle Krogh, Aanæs, Kasper, Wassermann, T., Alhede, M., von Buchwald, Christian & Høiby, Niels, 8 Mar 2013, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 12, 6, p. 729-736 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    90. Published

      Respiratory bacterial infections in cystic fibrosis

      Ciofu, Oana, Hansen, C. R. & Høiby, Niels, May 2013, In: Current Opinion in Pulmonary Medicine. 19, 3, p. 251-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    91. Published

      Anvendelse af antibiotika i tandlægepraksis

      Larsen, Tove, Ciofu, Oana, Moesby, L., Kirkevang, L. & Havemose-Poulsen, A., Sep 2013, In: Tandlaegebladet. 117, 9, p. 718-729 12 p., 460.

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      Sublethal ciprofloxacin treatment leads to rapid development of high-level ciprofloxacin resistance during long-term experimental evolution of Pseudomonas aeruginosa

      Jørgensen, K. M., Wassermann, T., Jensen, Peter Østrup, Hengzuang, W., Molin, S., Høiby, Niels & Ciofu, Oana, Sep 2013, In: Antimicrobial Agents and Chemotherapy. 57, 9, p. 4215-21 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    93. Published

      Applying insights from biofilm biology to drug development - can a new approach be developed?

      Bjarnsholt, Thomas, Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Oct 2013, In: Nature Reviews. Drug Discovery. 12, 10, p. 791-808 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. 2014
    95. Published

      Antioxidant supplementation for lung disease in cystic fibrosis

      Ciofu, Oana & Lykkesfeldt, Jens, 2014, In: The Cochrane library. 2014, 8, 87 p., CD007020.

      Research output: Contribution to journal › Journal article › Research › peer-review

    96. Published

      Bactericidal effect of colistin on planktonic Pseudomonas aeruginosa is independent of hydroxyl radical formation

      Brochmann, R. P., Toft, A., Ciofu, Oana, Briales, A., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, 2014, In: International Journal of Antimicrobial Agents. 43, 2, p. 140-147 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    97. Published

      Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms

      Jensen, Peter Østrup, Briales, A., Brochmann, R. P., Wang, H., Kragh, K. N., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Ciofu, Oana, 2014, In: Pathogens and Disease. 70, 3, p. 440-443 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    98. Published

      Pharmacokinetics and pharmacodynamics of antibiotics in biofilm infections of Pseudomonas aeruginosa in vitro and in vivo

      Hengzhuang, W., Høiby, Niels & Ciofu, Oana, 2014, In: Methods in molecular biology (Clifton, N.J.). 1147, p. 239-54 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Published

      Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum

      Line, L., Alhede, M., Kolpen, Mette, Kühl, Michael, Ciofu, Oana, Bjarnsholt, Thomas, Moser, Claus Ernst, Toyofuku, M., Nomura, N., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Frontiers in Microbiology. 5, 11 p., 554.

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. 2015
    101. Published

      Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

      Ciofu, Oana, Tolker-Nielsen, Tim, Jensen, Peter Østrup, Wang, H. & Høiby, Niels, 2015, In: Advanced Drug Delivery Reviews. 85, p. 7-23 17 p.

      Research output: Contribution to journal › Review › Research › peer-review

    102. Published

      Chronic Infection with Pseudomonas aeruginosa in an animal model of oxidative stress: lessons for patients with cystic fibrosis

      Ciofu, Oana, 2015, Diet and Exercise in Cystic Fibrosis. Ross Watson, R. (ed.). London: Academic Press, p. 171-176

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    103. Published

      Kompendium i mikrobiologi og infektionsmedicin

      Høiby, N., Skinhøj, P., Andersen, Å. B., Andersen, Leif Percival, Arendrup, M. C., Christiansen, C. B., Ciofu, Oana, Gerstoft, Jan, Johansen, Helle Krogh, Kemp, M., Kurtzhals, Jørgen, Nielsen, L. P., Lyngsøe Svejgaard, E., Theander, Thor Grundtvig & Thomsen, Allan Randrup, 2015, 1. ed. FADL's Forlag.

      Research output: Book/Report › Book › Education

    104. Published

      The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

      Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    105. Published

      Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection

      Jorgensen, K. M., Wassermann, T., Johansen, Helle Krogh, Christiansen, L. E., Molin, S., Høiby, Niels & Ciofu, Oana, Jul 2015, In: Microbiology. 161, 7, p. 1447-1462 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    106. Published

      RE-SENSITIZATION OF ANOXIC PSEUDOMONAS AERUGINOSA BIOFILMS WITH RE-OXYGENATION USING HYPERBARIC OXYGEN TREATMENT

      Kolpen, Mette, Mousavi, N., Sams, T., Kragh, K. N., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, P. O., Oct 2015, In: Pediatric Pulmonology. 50, S41, p. 312-312 1 p., 322.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    107. Published

      Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients

      Marvig, R. L., Dolce, D., Sommer, L. M., Petersen, Bent, Ciofu, Oana, Campana, S., Molin, S., Taccetti, G. & Johansen, Helle Krogh, 19 Oct 2015, In: B M C Microbiology. 15, 13 p., 218.

      Research output: Contribution to journal › Journal article › Research › peer-review

    108. 2016
    109. Published

      Genome sequence of Pseudomonas aeruginosa strain DK1-NH57388A, a stable mucoid cystic fibrosis isolate

      Norman, A., Ciofu, Oana, Amador, C. I., Høiby, Niels & Jelsbak, L., 2016, In: Genome Announcements. 4, 1, e00008-16.

      Research output: Contribution to journal › Journal article › Research

    110. Published

      OligoG CF-5/20 disruption of mucoid Pseudomonas aeruginosa biofilm in a murine lung infection model

      Wang, H., Song, Z., Ciofu, Oana, Onsøyen, E., Rye, P. D. & Høiby, Niels, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 5, p. 2620-2626 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    111. Published

      Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment

      Kolpen, Mette, Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    112. Published

      Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions

      Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.

      Research output: Contribution to journal › Journal article › Research › peer-review

    113. Published

      The phenotypic evolution of pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin

      Wassermann, T., Jørgensen, K. M., Ivanyshyn, K., Bjarnsholt, Thomas, Hossein Khademi, S. M., Jelsbak, L., Høiby, Niels & Ciofu, Oana, 1 May 2016, In: Microbiology. 162, 5, p. 865-875 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    114. Published

      Proteome-wide antigen discovery of novel protective vaccine candidates against Staphylococcus aureus infection

      Rasmussen, K. J., Mattsson, A. H., Pilely, K., Asferg, C. A., Ciofu, Oana, Vitved, L., Koch, C. & Kemp, M., 31 Aug 2016, In: Vaccine. 34, 38, p. 4602-4609 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    115. 2017
    116. Published

      Phenotypic shift in Pseudomonas aeruginosa populations from cystic fibrosis lungs after 2-week antipseudomonal treatment

      Fernandez-Barat, L., Ciofu, Oana, Kragh, K. N., Pressler, T., Johansen, U., Motos, A., Torres, A. & Høiby, Niels, Mar 2017, In: Journal of Cystic Fibrosis. 16, 2, p. 222-229

      Research output: Contribution to journal › Journal article › Research › peer-review

    117. Published

      Real-Time Monitoring of nfxB Mutant Occurrence and Dynamics in Pseudomonas aeruginosa Biofilm Exposed to Subinhibitory Concentrations of Ciprofloxacin

      Zaborskytė, G., Andersen, Jens Bo, Kragh, K. N. & Ciofu, Oana, Mar 2017, In: Antimicrobial Agents and Chemotherapy. 61, 3, 14 p., e02292-16.

      Research output: Contribution to journal › Journal article › Research › peer-review

    118. Published

      Antibiotic treatment of biofilm infections

      Ciofu, Oana, Rojo-Molinero, E., Macià, M. D. & Oliver, A., Apr 2017, In: APMIS. 125, 4, p. 304-319 16 p.

      Research output: Contribution to journal › Review › Research › peer-review

    119. Published

      Diagnosis of biofilm infections in cystic fibrosis patients

      Høiby, Niels, Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup, Kolpen, Mette, Qvist, T., Aanæs, Kasper, Pressler, T., Skov, M. & Ciofu, Oana, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 339-343 5 p.

      Research output: Contribution to journal › Review › Research › peer-review

    120. Published

      Detection of multidrug-resistant bacteria in the occupied Palestinian territory: a cross-sectional study

      Sjolander, I., Hansen, F., Elmanama, A., Khayyat, R., Abu-Zant, A., Hussein, A., Abu Taha, A., Hammerum, A. M. & Ciofu, Oana, Aug 2017, In: Lancet Oncology. 390, S1, p. S12

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    121. Published

      Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin

      Kolpen, Mette, Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.

      Research output: Contribution to journal › Journal article › Research › peer-review

    122. 2018
    123. Published

      Adaptation of Pseudomonas aeruginosa to the chronic phenotype by mutations in the algTmucABD operon in isolates from Brazilian cystic fibrosis patients

      Caçador, N. C., Paulino da Costa Capizzani, C., Monteiro Marin Torres, L. A. G., Galetti, R., Ciofu, Oana, Lúcia da Costa Darini, A. & Høiby, Niels, 2018, In: PLoS ONE. 13, 11, 11 p., e0208013.

      Research output: Contribution to journal › Journal article › Research › peer-review

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