Thomas Bjarnsholt
Professor
Bacteriology
Nørre Allé 14
2200 København N
- 2024
- Published
Bacterial micro-aggregates as inoculum in animal models of implant-associated infections
Hartmann, Katrine Top, Lund Nielsen, R., Mikkelsen, F. C., Aalbæk, Bent, Lichtenberg, Mads, Jakobsen, Tim Holm, Bjarnsholt, Thomas, Kvich, Lasse Andersson, Ingmer, Hanne, Odgaard, Anders, Jensen, Henrik Elvang & Jensen, Louise Kruse, Jun 2024, In: Biofilm. 7, 12 p., 100200.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Antibiotic implant irrigation and deep infection: A retrospective study of 1508 patients undergoing breast reconstruction with implants
Hemmingsen, Mathilde Nejrup, Bennedsen, A. K., Kullab, R. B., Weltz, T. K., Ørholt, M., Norlin, C. B., Kalstrup, J., Bredgaard, R., Sørensen, Søren Johannes, Bjarnsholt, Thomas, Hølmich, Lisbet Rosenkrantz, Damsgaard, T. E., Vester-Glowinski, Peter Viktor & Herly, Mikkel, 2024, (E-pub ahead of print) In: Plastic and Reconstructive Surgery. 26 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Bacterial aerobic respiration is a major consumer of oxygen in sputum from patients with acute lower respiratory tract infection
Jensen, Peter Østrup, Olsen, P., Dungu, A. M., Egelund, G. B., Jensen, A. V., Ravn, P., Lindegaard, Birgitte, Hertz, Frederik Boëtius, Bjarnsholt, Thomas, Faurholt-Jepsen, D. & Kolpen, Mette, 2024, (E-pub ahead of print) In: APMIS.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilms and core pathogens shape the tumor microenvironment and immune phenotype in colorectal cancer
Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Zschach, Henrike, Terkelsen, Thilde Bagger, Raskov, H., Høst-Rasmussen, K., Jakobsen, M. R., Gheorghe, Alexandra Gabriella, Gögenur, Ismail & Bjarnsholt, Thomas, 2024, In: Gut Microbes. 16, 1, 2350156.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Centennial celebrations of the Danish Pasteur Society
Høiby, Niels & Bjarnsholt, Thomas, 2024, In: APMIS. 132, 1, p. 3Research output: Contribution to journal › Editorial › Research
- E-pub ahead of print
Eradication of Staphylococcus aureus in Implant-Associated Osteomyelitis by an Injectable in situ-Forming Depot Antibiotics Delivery System
Fuglsang-Madsen, A. J., Henriksen, Nicole Lind, Chávez, E. S., Kvich, Lasse Andersson, Birch, Julie Knippel Melsted, Hartmann, Katrine Top, Eriksen, Thomas, Bjarnsholt, Thomas, Gottlieb, Hans, Andresen, T. L., Jensen, Louise Kruse, Henriksen, J. R. & Hansen, A. E., 2024, (E-pub ahead of print) In: The Journal of Infectious Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of Pseudomonas aeruginosa quorum sensing by chemical induction of the MexEF-oprN efflux pump
Kristensen, Rasmus, Andersen, Jens Bo, Rybtke, Morten Levin, Jansen, C. U., Fritz, Blaine Gabriel, Kiilerich, R. O., Uhd, J., Bjarnsholt, Thomas, Qvortrup, K., Tolker-Nielsen, Tim, Givskov, Michael & Jakobsen, Tim Holm, 2024, In: Antimicrobial Agents and Chemotherapy. 68, 2Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel sampling technique maintaining the two-dimensional organization of microbes during cultivation from chronic wounds: The Imprint method
Iversen, A. K. S., Fritz, Blaine Gabriel, Hansen, M. J., Kirketerp-Møller, K., Jakobsen, Tim Holm, Bjarnsholt, Thomas & Lichtenberg, Mads, 2024, In: APMIS. 132, p. 210-220Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictive metagenomic analysis identifies specific bacterial metabolic pathways in hidradenitis suppurativa tunnels
Ring, H. C., Thorsen, J., Lilje, B., Bay, Lene, Bjarnsholt, Thomas, Fuursted, K., Saunte, Ditte Marie, Jemec, Gregor & Thomsen, Simon Francis, 2024, In: Journal of the European Academy of Dermatology and Venereology. 38, 1, p. e63-e65Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
RNA-sequencing of paired tape-strips and skin biopsies in atopic dermatitis reveals key differences
Fritz, Blaine Gabriel, Halling, A. S., Diaz-Pines Cort, Isabel, Christensen, M. O., Rønnstad, A. T. M., Olesen, C. M., Knudgaard, M. H., Zachariae, Claus, Heegaard, Steffen, Thyssen, Jacob Pontoppidan & Bjarnsholt, Thomas, 2024, In: Allergy: European Journal of Allergy and Clinical Immunology. p. 1548-1559Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Single cells and bacterial biofilm populations in chronic wound infections
Lichtenberg, Mads, Kirketerp-Møller, K., Kvich, Lasse Andersson, Christensen, Mads Holm, Fritz, Blaine Gabriel, Jakobsen, Tim Holm & Bjarnsholt, Thomas, 2024, (E-pub ahead of print) In: APMIS.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
What is slough? Defining the proteomic and microbial composition of slough and its implications for wound healing
Townsend, E. C., Cheong, J. Z. A., Radzietza, M., Fritz, Blaine Gabriel, Malone, M., Bjarnsholt, Thomas, Ousey, K., Swanson, T., Schultz, G., Gibson, A. L. F. & Kalan, L. R., 2024, (E-pub ahead of print) In: Wound Repair and Regeneration.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism
Adams, Yvonne, Clausen, Anne Skovsbo, Jensen, Peter Østrup, Lager, M., Wilhelmsson, P., Henningson, A. J., Lindgren, P. E., Faurholt-Jepsen, D., Mens, H., Kraiczy, P., Kragh, K. N., Bjarnsholt, Thomas, Kjær, Andreas, Lebech, Anne-Mette & Jensen, Anja Ramstedt, 2023, In: iScience. 26, 1, 105838.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A collagen-based layered chronic wound biofilm model for testing antimicrobial wound products
Thaarup, Ida Clement, Lichtenberg, Mads, Nørgaard, K. T. H., Xu, Y., Lorenzen, J., Thomsen, T. R. & Bjarnsholt, Thomas, 2023, In: Wound Repair and Regeneration. 31, 4, p. 500-515Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A simplified bacterial community found within the epidermis than at the epidermal surface of atopic dermatitis patients and healthy controls
Barnes, Christopher James, Asplund, M., Clausen, M., Rasmussen, Linett, Olesen, C. M., Yüksel, Y. T., Andersen, P. S., Litman, Thomas, Holmstrøm, K., Bay, Lene, Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Agner, Tove & Hansen, Anders Johannes, 2023, In: BMC Microbiology. 23, 12 p., 273.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adaptation of Pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor C-30 during experimental evolution requires multiple genotypic and phenotypic changes
Bové, M., Kolpen, Mette, Lichtenberg, Mads, Bjarnsholt, Thomas & Coenye, T., 2023, In: Microbiology (United Kingdom). 169, 1, 001278.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilm formation on endovascular aneurysm repair (EVAR) grafts- a proof of concept in vitro model
Sunnerhagen, T., Schwartz, F., Christophersen, L., Bjarnsholt, Thomas, Qvortrup, Klaus, Eldrup, Nikolaj, Vogt, K. & Moser, Claus Ernst, 2023, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 29, 12, p. 1600.e1-1600.e6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebral abscesses with odontogenic origin: a population-based cohort study
Jespersen, Frederik Viktor Bang, Hansen, S. U., Jensen, Simon Storgård, Omland, L. H., Helweg-Larsen, J., Bjarnsholt, Thomas, Nielsen, Claus Henrik, Ziebell, M., Bodilsen, J. & Markvart, Merete, 2023, In: Clinical Oral Investigations. 27, 7, p. 3639-364Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of patients with odontogenic necrotizing soft tissue infections in the head and neck area: A retrospective analysis
Hansen, S. U., Jespersen, Frederik Viktor Bang, Markvart, Merete, Hyldegaard, Ole, Plaschke, Christina Caroline, Bjarnsholt, Thomas, Nielsen, Claus Henrik & Jensen, Simon Storgård, 2023, In: Acta Odontologica Scandinavica. 82, 1, p. 40-47Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of pig skin microbiome and appraisal as an in vivo subcutaneous injection model
Wareham-Mathiassen, S., Pinto Glenting, V., Bay, Lene, Allesen-Holm, M., Bengtsson, H. & Bjarnsholt, Thomas, 2023, In: Laboratory Animals. 57, 2, p. 304-318Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Defining the temporal relationship between the skin microbiome, immune response and skin barrier function during flare and resolution of atopic dermatitis: protocol of a Danish intervention study
Rønnstad, A. T. M., Bay, Lene, Ruge, I. F., Halling, A., Fritz, Blaine Gabriel, Jakaša, I., Luiten, R., Kezic, S., Thomsen, Simon Francis, Bjarnsholt, Thomas & Thyssen, Jacob Pontoppidan, 2023, In: BMJ Open. 13, 2, 8 p., e068395.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct 16S/18S rRNA Gene PCR Followed by Sanger Sequencing as a Clinical Diagnostic Tool for Detection of Bacterial and Fungal Infections: a Systematic Review and Meta-Analysis
Drevinek, P., Hollweck, R., Lorenz, M. G., Lustig, M. & Bjarnsholt, Thomas, 2023, In: Journal of clinical microbiology. 61, 9, e0033823.Research output: Contribution to journal › Review › Research › peer-review
- Published
E-cadherin and aquaporin-3 are downregulated in wound edges of human chronic wounds
Ernstsen, C. V., Riishede, A., Iversen, A. K. S., Bay, Lene, Bjarnsholt, Thomas & Nejsum, L. N., 2023, In: APMIS. 131, 8, p. 403-409Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endolysin Inhibits Skin Colonization by Patient-Derived Staphylococcus Aureus and Malignant T-Cell Activation in Cutaneous T-Cell Lymphoma
Pallesen, E. M. H., Gluud, M., Vadivel, C. K., Buus, T. B., de Rooij, B., Zeng, Z., Ahmad, S., Willerslev-Olsen, A., Röhrig, C., Kamstrup, M. R., Bay, L., Lindahl, L., Krejsgaard, T., Geisler, C., Bonefeld, C. M., Iversen, L., Woetmann, A., Koralov, S. B., Bjarnsholt, T., Frieling, J. & 2 others, , 2023, In: Journal of Investigative Dermatology. 143, 9, p. 1757-1769 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbial Primer: In vivo biofilm
Rumbaugh, K. P. & Bjarnsholt, Thomas, 2023, In: Microbiology (United Kingdom). 169, 12, 5 p., 001407.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacokinetics of Locally Applied Antibiotic Prophylaxis for Implant-Based Breast Reconstruction
Hemmingsen, Mathilde Nejrup, Bennedsen, A. K., Kullab, R. B., Norlin, C. B., Ørholt, M., Larsen, A., Bue, M., Lichtenberg, Mads, Hertz, Frederik Boëtius, Damsgaard, T. E., Vester-Glowinski, Peter Viktor, Sørensen, Søren Johannes, Bjarnsholt, Thomas & Herly, Mikkel, 2023, In: JAMA network open. 6, 12, 11 p., E2348414.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protocol to assess metabolic activity of Pseudomonas aeruginosa by measuring heat flow using isothermal calorimetry
Beilharz, K., Kragh, K. N., Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Tolker-Nielsen, Tim, Bjarnsholt, Thomas & Lichtenberg, Mads, 2023, In: STAR Protocols. 4, 2, 102269.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced Skin Microbiome Diversity in Infancy Is Associated with Increased Risk of Atopic Dermatitis in High-Risk Children
Halling, A. S., Fritz, Blaine Gabriel, Gerner, T., Rinnov, M. R., Bay, Lene, Knudgaard, M. H., Ravn, N. H., Trautner, S., Ruge, I. F., Olesen, C., Díiaz-Pinées Cort, I., Skov, Lone, Sørensen, N., Møller Rønnstad, A. T., Thomsen, Simon Francis, Egeberg, Alexander, Jakasa, I., Kezic, S., Bjarnsholt, Thomas & Thyssen, Jacob Pontoppidan, 2023, In: Journal of Investigative Dermatology. 143, 10, p. 2030-2038 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rethinking the Inoculum Used in Animal Models of Implant-Associated Osteomyelitis – The Formation and Application of Bacterial Aggregates
Hartmann, Katrine Top, Nielsen, R. L., Mikkelsen, F. C., Ingmer, Hanne, Kvich, Lasse Andersson, Aalbæk, Bent, Odgaard, Anders, Jensen, Henrik Elvang, Lichtenberg, Mads, Bjarnsholt, Thomas & Jensen, Louise Kruse, 2023, p. 59. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
What's in a name? Characteristics of clinical biofilms
Lichtenberg, Mads, Coenye, T., Parsek, M. R., Bjarnsholt, Thomas & Jakobsen, Tim Holm, 2023, In: FEMS Microbiology Reviews. 47, 5, p. 1-8 fuad050.Research output: Contribution to journal › Review › Research › peer-review
- 2022
- Published
A novel Borrelia-specific real-time PCR assay is not suitable for diagnosing Lyme neuroborreliosis
Pedersen, Regitze Renee, Kragh, K. N., Fritz, Blaine Gabriel, Ørbæk, M., Jensen, Peter Østrup, Lebech, Anne-Mette & Bjarnsholt, Thomas, 2022, In: Ticks and Tick-borne Diseases. 13, 5, 101971.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
APMIS 2022 focus issue on human microbiome in disease and pathology
Bjarnsholt, Thomas, Ralfkiaer, U. & Malone, M., 2022, In: APMIS. 130, 12, p. 689 1 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Amplicon sequencing demonstrates comparable follicular mycobiomes in patients with hidradenitis suppurativa compared with healthy controls
Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Egeberg, Alexander, Ingham, Andreas, Vedel Nielsen, H., Frew, J. W., Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 7, p. e580-e583 4 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Bacterial biofilms predominate in both acute and chronic human lung infections
Kolpen, M., Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, Pernille, Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: Thorax. 77, p. 1015–1022Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial biofilms predominate in both acute and chronic human lung infections
Kolpen, Mette, Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, P., Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: European Respiratory Journal. Supplement. 60, Suppl. 66, 4.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilm Survival Strategies in Chronic Wounds
Thaarup, Ida Clement, Iversen, A. K. S., Lichtenberg, Mads, Bjarnsholt, Thomas & Jakobsen, Tim Holm, 2022, In: Microorganisms. 10, 4, 775.Research output: Contribution to journal › Review › Research › peer-review
- Published
Biofilm antimicrobial susceptibility through an experimental evolutionary lens
Coenye, T., Bové, M. & Bjarnsholt, Thomas, 2022, In: npj Biofilms and Microbiomes. 8, 82.Research output: Contribution to journal › Review › Research › peer-review
- Published
Cyclic-di-GMP signaling controls metabolic activity in Pseudomonas aeruginosa
Lichtenberg, Mads, Kragh, K. N., Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2022, In: Cell Reports. 41, 3, p. 111515 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Establishing a consensus on wound infection definitions
Haesler, E., Swanson, T., Ousey, K., Larsen, D., Carville, K., Bjarnsholt, Thomas & Haesler, P., 2022, In: Journal of Wound Care. 31, S12, p. S48-S59Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IWII Wound Infection in Clinical Practice consensus document: 2022 update
Swanson, T., Ousey, K., Haesler, E., Bjarnsholt, Thomas, Carville, K., Idensohn, P., Kalan, L., Keast, D. H., Larsen, D., Percival, S., Schultz, G., Sussman, G., Waters, N. & Weir, D., 2022, In: Journal of Wound Care. 31, S12, p. S10-S21Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Injection site microflora in persons with diabetes: why needle reuse is not associated with increased infections?
Wareham-Mathiassen, S., Bay, Lene, Glenting, V. P., Fatima, N., Bengtsson, H. & Bjarnsholt, Thomas, 2022, In: APMIS. 130, 7, p. 404-416 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inoculum Concentration Influences Pseudomonas aeruginosa Phenotype and Biofilm Architecture
Lichtenberg, Mads, Kvich, Lasse Andersson, Larsen, S. L. B., Jakobsen, Tim Holm & Bjarnsholt, Thomas, 2022, In: Microbiology Spectrum. 10, 6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of the mechanism and chemistry underlying Staphylococcus aureus' ability to inhibit Pseudomonas aeruginosa growth in vitro
Kvich, Lasse Andersson, Crone, S. G., Christensen, M. H., Lima, R. D. C. L., Alhede, M., Alhede, M., Stærk, Dan & Bjarnsholt, Thomas, 2022, In: Journal of Bacteriology. 204, 11, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mucoid Pseudomonas aeruginosa Can Produce Calcium-Gelled Biofilms Independent of the Matrix Components Psl and CdrA
Jacobs, H. M., O'Neal, L., Lopatto, E., Wozniak, D. J., Bjarnsholt, Thomas & Parsek, M. R., 2022, In: Journal of Bacteriology. 204, 5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence of biofilms in acute infections challenges a longstanding paradigm
Kolpen, M., Jensen, Peter Østrup, Faurholt-Jepsen, D. & Bjarnsholt, Thomas, 2022, In: Biofilm. 4, 100080.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probiotics in hidradenitis suppurativa: a potential treatment option?
Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Clinical and Experimental Dermatology. 47, 1, p. 139-141 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: protocol for a randomised, double-blind, placebo-controlled trial (The BREAST-AB trial)
Hemmingsen, M. N., Larsen, A., Weltz, T. K., Ørholt, M., Wiberg, S., Bennedsen, A. K., Bille, C., Carstensen, L. F., Jensen, L. T., Bredgaard, R., Koudahl, V., Schmidt, Volker-Jürgen, Vester-Glowinski, Peter Viktor, Hølmich, Lisbet Rosenkrantz, Sørensen, Søren Johannes, Bjarnsholt, Thomas, Damsgaard, Tine M Engberg & Herly, Mikkel, 2022, In: BMJ Open. 12, 9, p. e058697Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Combination of Low-Frequency Ultrasound and Antibiotics Improves the Killing of In Vitro Staphylococcus aureus and Pseudomonas aeruginosa Biofilms
Kvich, Lasse Andersson, Christensen, M. H., Pierchala, M. K., Astafiev, K., Lou-Moeller, R. & Bjarnsholt, Thomas, 2022, In: Antibiotics. 11, 11, 1494.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The biofilm life cycle: expanding the conceptual model of biofilm formation
Sauer, K., Stoodley, P., Goeres, D. M., Hall-Stoodley, L., Burmølle, Mette, Stewart, P. S. & Bjarnsholt, Thomas, 2022, In: Nature Reviews Microbiology. 20, 10, p. 608-620 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The gut microbiota can orchestrate the signaling pathways in colorectal cancer
Bennedsen, A. L. B., Furbo, S., Bjarnsholt, Thomas, Raskov, H., Gögenur, Ismail & Kvich, Lasse Andersson, 2022, In: APMIS. 130, 3, p. 121-139 19 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The importance of understanding the infectious microenvironment
Bjarnsholt, Thomas, Whiteley, M., Rumbaugh, K. P., Stewart, P. S., Jensen, Peter Østrup & Frimodt-Møller, N., 2022, In: The Lancet Infectious Diseases. 22, 3, p. e88-e92Research output: Contribution to journal › Review › Research › peer-review
- Published
The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment
Lichtenberg, Mads, Jakobsen, Tim Holm, Kühl, Michael, Kolpen, Mette, Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: FEMS Microbiology Reviews. 46, 5, 13 p., fuac018.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic Fingerprint of Bacterial Infection in Lower Extremity Ulcers
Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Nielsen, C. H., Kirketerp-Møller, K., Malone, M. & Bjarnsholt, Thomas, 2022, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 130, 8, p. 524-534Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of implant-associated osteomyelitis with injectable in situ-forming depot drug delivery system
Fuglsang-Madsen, A., Henriksen, Nicole Lind, Kvich, Lasse Andersson, Birch, Julie Knippel Melsted, Hartmann, Katrine Top, Bjarnsholt, Thomas, Andresen, T. L., Jensen, Louise Kruse, Henriksen, J. R. & Hansen, A. E., 2022.Research output: Contribution to conference › Conference abstract for conference › Communication
- 2021
- Published
Delayed neutrophil recruitment allows nascent Staphylococcus aureus biofilm formation and immune evasion
Pettygrove, B. A., Kratofil, R. M., Alhede, M., Jensen, Peter Østrup, Newton, M., Qvortrup, Klaus, Pallister, K. B., Bjarnsholt, Thomas, Kubes, P., Voyich, J. M. & Stewart, P. S., Aug 2021, In: Biomaterials. 275, 13 p., 120775.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel chronic wound biofilm model sustaining coexistence of Pseudomonas aeruginosa and Staphylococcus aureus suitable for testing of antibiofilm effect of antimicrobial solutions and wound dressings
Chen, X., Lorenzen, J., Xu, Y., Jonikaite, M., Thaarup, Ida Clement, Bjarnsholt, Thomas, Kirketerp-Møller, K. & Thomsen, T. R., 2021, In: Wound Repair and Regeneration. 29, 5, p. 820-829Research output: Contribution to journal › Journal article › Research › peer-review
- Published
APMIS pandemic editorial
Bjarnsholt, Thomas & Calum, Henrik Pierre, 2021, In: APMIS: Acta Pathologica, Microbiologica et Immunologica Scandinavica. 129, 7, p. 319 1 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
- Published
Biofilm and equine limb wounds
Jørgensen, Elin , Bjarnsholt, Thomas & Jacobsen, Stine, 2021, In: Animals. 11, 10, 2825.Research output: Contribution to journal › Review › Research › peer-review
- Published
Biofilms can act as plasmid reserves in the absence of plasmid specific selection
Røder, Henriette Lyng, Trivedi, Urvish, Russel, J., Kragh, K. N., Herschend, J., Thalsø-Madsen, I., Tolker-Nielsen, Tim, Bjarnsholt, Thomas, Burmølle, Mette & Madsen, Jonas Stenløkke, 2021, In: npj Biofilms and Microbiomes. 7, 6 p., 78.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Catalase protects biofilm of Staphylococcus aureus against daptomycin activity
El Haj, C., Lichtenberg, Mads, Nielsen, K. L., Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: Antibiotics. 10, 5, 511.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Current in vitro biofilm-infected chronic wound models for developing new treatment possibilities
Thaarup, Ida Clement & Bjarnsholt, Thomas, 2021, In: Advances in Wound Care. 10, 2, p. 91-102 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamics of skin microbiota in shoulder surgery infections
Fatima, N., Bjarnsholt, Thomas & Bay, Lene, 2021, In: APMIS. 129, 12, p. 665-674Research output: Contribution to journal › Review › Research › peer-review
- Published
Measuring enzymatic degradation of degradable starch microspheres using confocal laser scanning microscopy
Thaarup, Ida Clement, Gummesson, C. & Bjarnsholt, Thomas, 2021, In: Acta Biomaterialia. 131, p. 464-471Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa
Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, Morten Levin, Toyofuku, M., Nomura, N., Kolpen, Mette, Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptidoglycan-Binding Anchor Is a Pseudomonas aeruginosa OmpA Family Lipoprotein With Importance for Outer Membrane Vesicles, Biofilms, and the Periplasmic Shape
Paulsson, M., Kragh, K. N., Su, Y. C., Sandblad, L., Singh, B., Bjarnsholt, Thomas & Riesbeck, K., 2021, In: Frontiers in Microbiology. 12, 639582.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sampling challenges in diagnosis of chronic bacterial infections
Jakobsen, Tim Holm, Xu, Y., Bay, Lene, Schønheyder, H. C., Jakobsen, T., Bjarnsholt, Thomas & Thomsen, T. R., 2021, In: Journal of Medical Microbiology. 70, 3Research output: Contribution to journal › Review › Research › peer-review
- Published
The discovery of bacterial biofilm in patients with muscle invasive bladder cancer
Nadler, N., Kvich, Lasse Andersson, Bjarnsholt, Thomas, Jensen, J. B., Gögenur, Ismail & Azawi, Nessn H., 2021, In: APMIS. 129, 5, p. 265-270Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of mental models on the treatment and research of chronic infections due to biofilms
Bjarnsholt, Thomas, Mastroianni, E., Kirketerp-Møller, K., Stewart, P. S., Mähr, A. M., Domínguez Cabañes, A. & Nørager, R., 2021, In: APMIS. 129, 10, p. 598-606Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Staphylococcus aureus augments release of matrix metalloproteinase-8 from human polymorphonuclear leukocytes
Kirketerp-Møller, K., Bjarnsholt, Thomas, Jensen, Peter Østrup & Ågren, Magnus, 2020, In: Acta Dermato-Venereologica. 100, 15, p. 1-2 2 p., adv00232.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic susceptibility of cystic fibrosis lung microbiome members in a multispecies biofilm
Vandeplassche, E., Sass, A., Ostyn, L., Burmølle, Mette, Kragh, K. N., Bjarnsholt, Thomas, Coenye, T. & Crabbé, A., 2020, In: Biofilm. 2, 9 p., 100031.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes
Alhede, M., Lorenz, M., Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, H. C., Bay, Lene & Bjarnsholt, Thomas, 2020, In: Medical Microbiology and Immunology. 209, p. 669–680Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation
Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Copper-Silver alloy coated door handles as a potential antibacterial strategy in clinical settings
Ciacotich, N., Kvich, Lasse Andersson, Sanford, N., Wolcott, J., Bjarnsholt, Thomas & Gram, L., 2020, In: Coatings. 10, 8, 9 p., 790.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do Mixed-Species Biofilms Dominate in Chronic Infections? Need for in situ Visualization of Bacterial Organization
Kvich, Lasse Andersson, Burmølle, Mette, Bjarnsholt, Thomas & Lichtenberg, Mads, 2020, In: Frontiers in Cellular and Infection Microbiology. 10, 12 p., 396.Research output: Contribution to journal › Review › Research › peer-review
- Published
Does an Antimicrobial Incision Drape Prevent Intraoperative Contamination? A Randomized Controlled Trial of 1187 Patients
Hesselvig, A. B., Arpi, M., Madsen, F., Bjarnsholt, Thomas, Odgaard, Anders & ICON Study Group, I. S. G., 2020, In: Clinical Orthopaedics and Related Research. 478, 5, p. 1007-1015Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology
Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eradication of biofilms on tympanostomy tubes with acetic acid treatment: an in vitro study
Kjeldsen, M., Homøe, Preben, Nielsen, Anne Kirstine, Crone, S., Nørskov Kragh, K. & Bjarnsholt, Thomas, 2020, In: APMIS. 128, 6, p. 445-450Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histologic changes and gene expression patterns in biopsy specimens from bacteria-inoculated and noninoculated excisional body and limb wounds in horses healing by second intention
Jørgensen, Elin , Hjerpe, F. B., Hougen, H. P., Bjarnsholt, Thomas, Berg, Lise Charlotte & Jacobsen, Stine, 2020, In: American Journal of Veterinary Research. 81, 3, p. 276-284 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Minimum information guideline for spectrophotometric and fluorometric methods to assess biofilm formation in microplates
Allkja, J., Bjarnsholt, Thomas, Coenye, T., Cos, P., Fallarero, A., Harrison, J. J., Lopes, S. P., Oliver, A., Pereira, M. O., Ramage, G., Shirtliff, M. E., Stoodley, P., Webb, J. S., Zaat, S. A. J., Goeres, D. M. & Azevedo, N. F., 2020, In: Biofilm. 2, 8 p., 100010.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathogenic CD8+ epidermis-resident memory T cells displace dendritic epidermal T cells in allergic dermatitis
Ø Gadsbøll, A., Jee, Mia Hamilton, Funch, Anders Boutrup, Alhede, M., Mraz, Veronika, Weber, Julie Friis, Callender, L. A., Carroll, E. C., Bjarnsholt, Thomas, Woetmann, Anders , Ødum, Niels, Thomsen, Allan Randrup, Johansen, Jeanne Duus, Henson, S. M., Geisler, Carsten & Bonefeld, Charlotte Menne, 2020, In: The Journal of Investigative Dermatology. 140, 4, p. 806-815.e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathological and microbiological impact of a gentamicin-loaded biocomposite following limited or extensive debridement in a porcine model of osteomyelitis
Blirup-Plum, Sophie Amalie, Bjarnsholt, Thomas, Jensen, Henrik Elvang, Kragh, K. N., Aalbæk, Bent, Gottlieb, Hans, Bue, M. & Jensen, Louise Kruse, 2020, In: Bone and Joint Research. 9, 7, p. 394-401 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictive Metagenomic Analysis Reveals a Role of Cutaneous Dysbiosis in the Development of Hidradenitis Suppurativa
Ring, H. C., Thorsen, Jonathan Jan Ilve, Jørgensen, A. H., Bay, Lene, Bjarnsholt, Thomas, Fuursted, K., Thomsen, Simon Francis & Jemec, Gregor, 2020, In: Journal of Investigative Dermatology. 140, 7, p. 1473-1476Research output: Contribution to journal › Letter › Research › peer-review
- Published
Risk factors for chronic biofilm-related infection associated with implanted medical devices
Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Clinical Microbiology and Infection. 26, 8, p. 1034-1038Research output: Contribution to journal › Review › Research › peer-review
- Published
The efficacy of topical agents used in wounds for managing chronic biofilm infections: A systematic review
Schwarzer, S., James, G. A., Goeres, D., Bjarnsholt, Thomas, Vickery, K., Percival, S. L., Stoodley, P., Schultz, G., Jensen, S. O. & Malone, M., 2020, In: Journal of Infection. 80, 3, p. 261-270Research output: Contribution to journal › Review › Research › peer-review
- Published
The environmental occurrence of Pseudomonas aeruginosa
Crone, S., Vives-Flórez, M., Kvich, Lasse Andersson, Saunders, A. M., Malone, M., Nicolaisen, Mette Haubjerg, Martínez-García, E., Rojas-Acosta, C., Catalina Gomez-Puerto, M., Calum, Henrik Pierre, Whiteley, M., Kolter, R. & Bjarnsholt, Thomas, 2020, In: APMIS. 128, 3, p. 220-231Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The future of biofilm research – Report on the ‘2019 Biofilm Bash’
Coenye, T., Kjellerup, B., Stoodley, P. & Bjarnsholt, Thomas, 2020, In: Biofilm. 2, 9 p., 100012.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
The origin of extracellular DNA in bacterial biofilm infections in vivo
Alhede, M., Alhede, M., Qvortrup, Klaus, Kragh, K. N., Jensen, Peter Østrup, Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Pathogens and Disease. ftaa018.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The zone model: A conceptual model for understanding the microenvironment of chronic wound infection
Kirketerp-Møller, K., Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Wound Repair and Regeneration. 28, 5, p. 593-599Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Universal Dermal Microbiome in Human Skin
Bay, Lene, Barnes, Christopher James, Fritz, Blaine Gabriel, Thorsen, Jonathan Jan Ilve, Restrup, M. E. M., Rasmussen, Linett, Sørensen, J. K., Hesselvig, A. B., Odgaard, Anders, Hansen, Anders Johannes & Bjarnsholt, Thomas, 2020, In: mBio. 11, 1, 13 p., e02945-19.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Extensive debridement is fundamental for the success of an absorbable gentamicin loaded bio-composite
Jensen, Louise Kruse, Blirup-Plum, Sophie Amalie, Aalbæk, Bent, Bjarnsholt, Thomas, Kragh, K. N., Gottlieb, H., Bue, M. & Jensen, Henrik Elvang, 12 Sep 2019.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
An equine wound model to study effects of bacterial aggregates on wound healing
Jørgensen, Elin , Bay, Lene, Skovgaard, Lene Theil, Bjarnsholt, Thomas & Jacobsen, Stine, 2019, In: Advances in Wound Care. 8, 10, p. 487-498Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of proximal bone margins in diabetic foot osteomyelitis by conventional culture, DNA sequencing and microscopy
Malone, M., Fritz, Blaine Gabriel, Vickery, K., Schwarzer, S., Sharma, V., Biggs, N., Radzieta, M., Jeffries, T. T., Dickson, H. G., Jensen, S. O. & Bjarnsholt, Thomas, 2019, In: APMIS. 127, 10, p. 660-670 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms
Crabbé, A., Jensen, Peter Østrup, Bjarnsholt, Thomas & Coenye, T., 2019, In: Trends in Microbiology. 27, 10, p. 850-863Research output: Contribution to journal › Review › Research › peer-review
- Published
Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth
Høiby, Niels, Henneberg, K. Å., Wang, H., Stavnsbjerg, Camilla, Bjarnsholt, Thomas, Ciofu, Oana, Johansen, U. R. & Sams, T., 2019, In: International Journal of Antimicrobial Agents. 53, 5, p. 564-573Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients
Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air
Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-Jepsen, Daniel, Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Situ Monitoring of the Antibacterial Activity of a Copper-Silver Alloy Using Confocal Laser Scanning Microscopy and pH Microsensors
Ciacotich, N., Kragh, K. N., Lichtenberg, Mads, Tesdorpf, J. E., Bjarnsholt, Thomas & Gram, L., 2019, In: Global Challenges. 3, 11, 9 p., 1900044.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo gentamicin susceptibility test for prevention of bacterial biofilms in bone tissue and on implants
Jensen, Louise Kruse, Bjarnsholt, Thomas, Kragh, K. N., Aalbæk, Bent, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie, Pankoke, K., Petersen, A. & Jensen, Henrik Elvang, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 2, 10 p., e01889-18.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Into the well—A close look at the complex structures of a microtiter biofilm and the crystal violet assay
Kragh, K. N., Alhede, M., Kvich, Lasse Andersson & Bjarnsholt, Thomas, 2019, In: Biofilm. 1, 9 p., 100006.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9755066
Most downloads
-
2988
downloads
Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2839
downloads
Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1920
downloads
Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
Research output: Contribution to journal › Journal article › Research › peer-review
Published